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Tyrosine- protein kinase Fyn Activated CDC42 kinase 1 B cell linker B cell linker Ras-related protein Rap-1b Ras-related protein Rap-1b Proto-oncogene vav SHC- transforming protein 1 Rap guanine nucleotide exchange factor 2 GRB2-related adapter protein Tyrosine- protein kinase Fyn 1- phosphatidylinositol 4,5- bisphosphate phosphodiesterase gamma-1 Protein kinase C alpha type Protein kinase C beta type Calmodulin Calmodulin Calmodulin Serine/threonine- protein phosphatase 2B catalytic subunit alpha isoform Serine/threonine- protein phosphatase 2B catalytic subunit alpha isoform Serine/threonine- protein phosphatase 2B catalytic subunit alpha isoform ETS translocation variant 1 RAF proto-oncogene serine/threonine- protein kinase Dual specificity mitogen- activated protein kinase kinase 6 Mitogen- activated protein kinase 1 Transcription factor AP-1 Proto-oncogene c-Fos Ras-related C3 botulinum toxin substrate 1 Aurora kinase A Mitogen- activated protein kinase 13 ORAI calcium release- activated calcium modulator 1 ORAI calcium release- activated calcium modulator 1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 B-cell antigen receptor complex- associated protein alpha chain CD79b molecule Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 Nuclear factor of activated T-cells, cytoplasmic 1 Diacylglycerol Ca+ Ca+ H2O Phosphatidylinositol 4,5- bisphosphate Inositol 1,4,5- trisphosphate Pi Ca+ Phosphate Phosphate Phosphate Guanosine triphosphate Guanosine diphosphate Phosphate ion Phosphate Phosphate Phosphate Phosphate Calcium Phosphate Phosphate Phosphate Pi Pi B-cell receptor B cell ontogeny; autoimmunity; energy; immune response; Ig Production; GC formation endoplasmic reticulum Nucleus Cytoplasm Extracellular
Nucleus FYN TNK2 BLNK BLNK RAP1B RAP1B VAV1 SHC1 RAPGEF2 GRAP FYN PLCG1 PRKCA PRKCB CALM CALM CALM PPP3CA PPP3CA PPP3CA ETV1 RAF1 MAP2K6 MAPK1 JUN FOS RAC1 AURKA MAPK13 ORAI1 ORAI1 NFATC1 NFATC1 NFATC1 NFATC1 CD79A CD79B NFATC1 NFATC1 NFATC1 NFATC1 Diacylglycerol Calcium Calcium Water Phosphatidylinositol 4,5- bisphosphate Inositol 1,4,5- trisphosphate Phosphate Calcium Phosphate Phosphate B-cell receptor
FYN TNK2 BLNK BLNK RAP1B RAP1B VAV1 SHC1 RAPGEF2 GRAP FYN PLCG1 PRKCA PRKCB CALM CALM CALM PPP3CA PPP3CA PPP3CA ETV1 RAF1 MAP2K6 MAPK1 JUN FOS RAC1 AURKA MAPK13 ORAI1 ORAI1 NFATC1 NFATC1 NFATC1 NFATC1 CD79A CD79B NFATC1 NFATC1 NFATC1 NFATC1 Diacylg Ca+ Ca+ H2O P45P Inotp Pi Ca+ Pi Pi Pi GTP GDP PhosIon Pi Pi Pi Pi Ca2+ Pi Pi Pi Pi Pi BCR B cell ontogeny; autoimmunity; energy; immune response; Ig Production; GC formation endoplasmic reticulum Nucleus Cytoplasm Extracellular
Nucleus FYN TNK2 BLNK BLNK RAP1B RAP1B VAV1 SHC1 RAPGEF2 GRAP FYN PLCG1 PRKCA PRKCB CALM CALM CALM PPP3CA PPP3CA PPP3CA ETV1 RAF1 MAP2K6 MAPK1 JUN FOS RAC1 AURKA MAPK13 ORAI1 ORAI1 NFATC1 NFATC1 NFATC1 NFATC1 CD79A CD79B NFATC1 NFATC1 NFATC1 NFATC1 Diacylg Ca2+ Ca2+ H2O P45P Inotp Pi Ca2+ Pi Pi BCR