Isonicotinoyl radical + NADP → Isonicotinoyl-NADP adduct
Isonicotinoyl radical + NAD → Isonicotinoyl-NAD adduct
Isoniazid + Pyruvic acid → Isoniazid pyruvate + Water
Isoniazid + Oxoglutaric acid → Isoniazid α-ketoglutaric acid + Water
Glycine + Isonicotinic acid → Isonicotinylglycine
Acetyl-CoA + Isoniazid → Acetylisoniazid + Coenzyme A
Isoniazid + Water → Hydrazine + Isonicotinic acid
Hydrogen peroxide + Isoniazid → Diimine + Isonicotinoyl radical + 2 Water
Acetyl-CoA + Hydrazine → Acetylhydrazine + Coenzyme A
Glutathione + Hepatotoxins → R-S-Glutathione
Acetylhydrazine + Hydrogen Ion + NADPH + Oxygen → Hepatotoxins + NADP + Water
Acetyl-CoA + Acetylhydrazine → Coenzyme A + Diacetylhydrazine
Acetylisoniazid + Water → Acetylhydrazine + Isonicotinic acid