Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/PubChem-compound 6262
type: UnificationXref
id: 6262
db: PubChem-compound

Citrulline
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Citrulline

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/ChemSpider 127983
type: UnificationXref
id: 127983
db: ChemSpider

Reference/ChEBI CHEBI 16134
type: UnificationXref
id: CHEBI:16134
db: ChEBI

L-Aspartic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Aspartic acid

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Reference/CAS 110-17-8
type: UnificationXref
id: 110-17-8
db: CAS

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00327
type: UnificationXref
id: C00327
db: KEGG Compound

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Citrate cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110090
pathway component: SubPathwayInteraction110090
name: SubPathway

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc OXALACETIC ACID
type: UnificationXref
id: OXALACETIC_ACID
db: BioCyc

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003378
type: UnificationXref
id: HMDB0003378
db: HMDB

Compound/PW C001065 Cytoplasm/Stoichiometry/4.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 4.0

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Compound/PW C000035/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/UniProt Q6PH54
type: UnificationXref
id: Q6PH54
db: UniProt

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Reference/ChemSpider 1143
type: UnificationXref
id: 1143
db: ChemSpider

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

Excretion
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110099
pathway component: SubPathwayInteraction110099
name: SubPathway

Reference/BioCyc UREA
type: UnificationXref
id: UREA
db: BioCyc

Nitrogen metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110093
pathway component: SubPathwayInteraction110093
name: SubPathway

Pyrimidine metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110094
pathway component: SubPathwayInteraction110094
name: SubPathway

Alanine, aspartate and glutamate metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110095
pathway component: SubPathwayInteraction110095
name: SubPathway

Citrate cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110096
pathway component: SubPathwayInteraction110096
name: SubPathway

Arginine and proline metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110097
pathway component: SubPathwayInteraction110097
name: SubPathway

D-arginine and D-ornithine metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110098
pathway component: SubPathwayInteraction110098
name: SubPathway

Reference/TAXONOMY 7955
type: UnificationXref
id: 7955
db: TAXONOMY

L-Glutamic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Glutamic acid

Reference/BioCyc ARG
type: UnificationXref
id: ARG
db: BioCyc

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Adenosine monophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine monophosphate

Reference/ChemSpider 5735
type: UnificationXref
id: 5735
db: ChemSpider

Reference/BioCyc L-CITRULLINE
type: UnificationXref
id: L-CITRULLINE
db: BioCyc

Reference/SMPDB SMP0121169
type: UnificationXref
id: SMP0121169
db: SMPDB

Reference/ChEBI CHEBI 16480
type: UnificationXref
id: CHEBI:16480
db: ChEBI

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Reference/ChemSpider 945
type: UnificationXref
id: 945
db: ChemSpider

Reference/PubChem-compound 16950
type: UnificationXref
id: 16950
db: PubChem-compound

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Compound/PW C000035 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/HMDB HMDB0001096
type: UnificationXref
id: HMDB0001096
db: HMDB

Compound/PW C000088 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Carbamoyl phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 278
xref: Reference/BioCyc CARBAMOYL-P
xref: Reference/ChemSpider 272
xref: Reference/HMDB HMDB0001096
xref: Reference/CAS 590-55-6
xref: Reference/KEGG Compound C00169
xref: Reference/ChEBI CHEBI 17672
chemical formula: CH4NO5P
molecular weight: 140.98271
structure: ChemicalStructure/PW C000862

Compound/PW C000143 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 3.0

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Urea
type: SmallMolecule
cellular location: Extracellular Matrix
entity reference: Urea

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Compound/PW C000500/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/BioCyc L-ALPHA-ALANINE
type: UnificationXref
id: L-ALPHA-ALANINE
db: BioCyc

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00122
type: UnificationXref
id: C00122
db: KEGG Compound

Reference/CAS 56-41-7
type: UnificationXref
id: 56-41-7
db: CAS

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

N-Acetyl-L-glutamic acid
type: SmallMolecule
entity reference: N-Acetyl-L-glutamic acid

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

NADP
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NADP

Fumaric acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Fumaric acid

Transport10352
type: Transport
participant stoichiometry: Compound/PW C000200 Extracellular Matrix/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000200 Cytoplasm/Stoichiometry/1.0
right: Urea
spontaneous: true
left: Urea
name: Urea (→) Transport: Danio rerio, Cell, Cytoplasm to Danio rerio, Cell, Extracellular Matrix
conversion direction: REVERSIBLE

Phosphate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Phosphate

Carbamoyl phosphate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Carbamoyl phosphate

Citrulline
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00327
xref: Reference/CAS 372-75-8
xref: Reference/ChEBI CHEBI 16349
xref: Reference/PubChem-compound 6992098
xref: Reference/BioCyc L-CITRULLINE
xref: Reference/HMDB HMDB0000904
xref: Reference/ChemSpider 9367
chemical formula: C6H13N3O3
molecular weight: 175.09569
structure: ChemicalStructure/PW C000723

Reference/CAS 372-75-8
type: UnificationXref
id: 372-75-8
db: CAS

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C03406
type: UnificationXref
id: C03406
db: KEGG Compound

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/HMDB HMDB0000904
type: UnificationXref
id: HMDB0000904
db: HMDB

Reference/KEGG Compound C00014
type: UnificationXref
id: C00014
db: KEGG Compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/CAS 10102-43-9
type: UnificationXref
id: 10102-43-9
db: CAS

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Arginine Biosynthesis
type: Pathway
pathway order: PathwaySubPathway/110099
pathway order: PathwaySubPathway/110098
pathway order: PathwaySubPathway/110097
pathway order: PathwaySubPathway/110096
pathway order: PathwaySubPathway/110095
pathway order: PathwaySubPathway/110094
pathway order: PathwaySubPathway/110093
pathway order: PathwaySubPathway/110090
pathway order: PathwayEnzymeReaction/2124391
pathway order: PathwayEnzymeReaction/2124393
pathway order: PathwayEnzymeReaction/2124396
pathway order: PathwayEnzymeReaction/2124398
pathway order: PathwayEnzymeReaction/2124397
pathway order: PathwayEnzymeReaction/2124400
pathway order: PathwayEnzymeReaction/2124399
pathway order: PathwayEnzymeReaction/2124410
pathway order: PathwayEnzymeReaction/2124413
pathway order: PathwayEnzymeReaction/2124415
pathway order: PathwayEnzymeReaction/2124403
pathway order: PathwayTransport/2124417
pathway order: PathwayEnzymeReaction/2124407
pathway component: 3.5.3.1
pathway component: TransportCatalysis1521
pathway component: Reaction179742
pathway component: 6.3.4.5
pathway component: ReactionCatalysis169626
pathway component: ReactionCatalysis169625
pathway component: ReactionCatalysis169624
pathway component: ReactionCatalysis169621
pathway component: ReactionCatalysis169620
pathway component: Excretion
pathway component: Nitrogen metabolism
pathway component: Pyrimidine metabolism
pathway component: Alanine, aspartate and glutamate metabolism
pathway component: Citrate cycle
pathway component: Arginine and proline metabolism
pathway component: D-arginine and D-ornithine metabolism
pathway component: ReactionCatalysis169619
pathway component: 2.3.1.1
pathway component: Reaction179732
pathway component: ReactionCatalysis169618
pathway component: Reaction179731
pathway component: ReactionCatalysis169617
pathway component: ReactionCatalysis169616
pathway component: Reaction179737
pathway component: ReactionCatalysis169615
pathway component: ReactionCatalysis169614
pathway component: 6.3.1.2
pathway component: ReactionCatalysis169613
pathway component: Reaction179735
pathway component: Reaction179734
pathway component: Transport10352
pathway component: 1.14.13.39
pathway component: Reaction179738
xref: Reference/PathWhiz PW122457
xref: Reference/SMPDB SMP0121169
organism: Danio rerio

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

L-Glutamine
type: SmallMolecule
entity reference: L-Glutamine

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Carbamoyl phosphate
type: SmallMolecule
entity reference: Carbamoyl phosphate
name: SubPathwayOutput
name: SubPathwayInput

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/UniProt Q1LWI2
type: UnificationXref
id: Q1LWI2
db: UniProt

Aspartate aminotransferase
type: ProteinReference
xref: Reference/UniProt Q7ZWF5
organism: Danio rerio

Compound/PW C040034 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 3.0

Compound/PW C000888/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-L-glutamic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 9367
type: UnificationXref
id: 9367
db: ChemSpider

Reference/KEGG Compound C00036
type: UnificationXref
id: C00036
db: KEGG Compound

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000134
type: UnificationXref
id: HMDB0000134
db: HMDB

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/KEGG Compound C00041
type: UnificationXref
id: C00041
db: KEGG Compound

Adenosine diphosphate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Nitric oxide synthase
type: ProteinReference
xref: Reference/UniProt A7WK81
organism: Danio rerio

Argininosuccinate synthase
type: ProteinReference
xref: Reference/UniProt Q66I24
organism: Danio rerio

Glutaminase a
type: ProteinReference
xref: Reference/UniProt Q1LWI2
organism: Danio rerio

Glutamine synthetase
type: ProteinReference
xref: Reference/UniProt Q7T2P7
organism: Danio rerio

Carbamoyl-phosphate synthase 1, mitochondrial
type: ProteinReference
organism: Danio rerio

Ornithine carbamoyltransferase
type: ProteinReference
xref: Reference/UniProt E9QHD9
organism: Danio rerio

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Si:ch211-217a12.1
type: ProteinReference
organism: Danio rerio

Reference/KEGG Compound C00169
type: UnificationXref
id: C00169
db: KEGG Compound

N-acetylglutamate synthase, mitochondrial
type: ProteinReference
xref: Reference/UniProt E7FCP8
organism: Danio rerio

Glutamate dehydrogenase 1a
type: ProteinReference
xref: Reference/UniProt Q6NZ29
organism: Danio rerio

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Urea
type: SmallMolecule
entity reference: Urea
name: SubPathwayInput

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Urea
type: SmallMoleculeReference
xref: Reference/BioCyc UREA
xref: Reference/CAS 57-13-6
xref: Reference/KEGG Compound C00086
xref: Reference/HMDB HMDB0000294
xref: Reference/ChemSpider 1143
xref: Reference/PubChem-compound 1176
xref: Reference/ChEBI CHEBI 16199
chemical formula: CH4N2O
molecular weight: 60.032364
structure: ChemicalStructure/PW C000200

Reference/ChemSpider 10197150
type: UnificationXref
id: 10197150
db: ChemSpider

Oxoglutaric acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Oxoglutaric acid

N-Acetyl-L-glutamic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00624
xref: Reference/ChEBI CHEBI 12575
xref: Reference/HMDB HMDB0001138
xref: Reference/BioCyc ACETYL-GLU
xref: Reference/CAS 1188-37-0
xref: Reference/PubChem-compound 185
xref: Reference/ChemSpider 180
chemical formula: C7H11NO5
molecular weight: 189.06372
structure: ChemicalStructure/PW C000888

Reference/BioCyc FUM
type: UnificationXref
id: FUM
db: BioCyc

ChemicalStructure/PW C000148
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CC(=O)C(O)=O

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Argininosuccinate lyase
type: ProteinReference
xref: Reference/UniProt Q7SY44
organism: Danio rerio

Reference/ChEBI CHEBI 18012
type: UnificationXref
id: CHEBI:18012
db: ChEBI

Arginase
type: ProteinReference
xref: Reference/UniProt Q6PH54
organism: Danio rerio

Reference/ChEBI CHEBI 16199
type: UnificationXref
id: CHEBI:16199
db: ChEBI

Urea transporter
type: ProteinReference
xref: Reference/UniProt Q533H0

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

ChemicalStructure/PW C000396
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCCNC(N)=N)C(O)=O

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00062
type: UnificationXref
id: C00062
db: KEGG Compound

ChemicalStructure/PW C000036
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc AMMONIA
type: UnificationXref
id: AMMONIA
db: BioCyc

ChemicalStructure/PW C000035
type: ChemicalStructure
structure format: SMILES
structure data: N

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/CAS 590-55-6
type: UnificationXref
id: 590-55-6
db: CAS

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Argininosuccinate synthase
type: Protein
cellular location: Cytoplasm
entity reference: Argininosuccinate synthase

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Nitric oxide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0003378
xref: Reference/CAS 10102-43-9
xref: Reference/PubChem-compound 145068
xref: Reference/ChEBI CHEBI 16480
xref: Reference/ChemSpider 127983
xref: Reference/KEGG Compound C00533
xref: Reference/BioCyc NITRIC-OXIDE
chemical formula: NO
molecular weight: 29.997988
structure: ChemicalStructure/PW C001867

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/CAS 2387-71-5
type: UnificationXref
id: 2387-71-5
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/HMDB HMDB0001138
type: UnificationXref
id: HMDB0001138
db: HMDB

Reference/HMDB HMDB0000161
type: UnificationXref
id: HMDB0000161
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

L-Alanine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00041
xref: Reference/ChemSpider 5735
xref: Reference/ChEBI CHEBI 16977
xref: Reference/BioCyc L-ALPHA-ALANINE
xref: Reference/HMDB HMDB0000161
xref: Reference/CAS 56-41-7
xref: Reference/PubChem-compound 5950
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C000105

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/KEGG Compound C00077
type: UnificationXref
id: C00077
db: KEGG Compound

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Compound/PW C000105/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Alanine
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid
name: SubPathwayOutput

Reference/HMDB HMDB0000051
type: UnificationXref
id: HMDB0000051
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0000052
type: UnificationXref
id: HMDB0000052
db: HMDB

Reference/HMDB HMDB0000294
type: UnificationXref
id: HMDB0000294
db: HMDB

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Compound/PW C001316 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00086
type: UnificationXref
id: C00086
db: KEGG Compound

Reference/GENE ONTOLOGY GO 0031012
type: UnificationXref
id: GO:0031012
db: GENE ONTOLOGY

L-Aspartic acid
type: SmallMolecule
entity reference: L-Aspartic acid
name: SubPathwayInput

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

Oxalacetic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Oxalacetic acid

Arginase
type: Protein
cellular location: Cytoplasm
entity reference: Arginase

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

ReactionCatalysis169626
type: Catalysis
controller: Arginase
controlled: 3.5.3.1
control type: ACTIVATION

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

ReactionCatalysis169625
type: Catalysis
controller: Argininosuccinate lyase
controlled: Reaction179742
control type: ACTIVATION

Reference/UniProt Q6NZ29
type: UnificationXref
id: Q6NZ29
db: UniProt

ReactionCatalysis169624
type: Catalysis
controller: Argininosuccinate synthase
controlled: 6.3.4.5
control type: ACTIVATION

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

ReactionCatalysis169621
type: Catalysis
controller: Nitric oxide synthase
controlled: 1.14.13.39
control type: ACTIVATION

ReactionCatalysis169620
type: Catalysis
controller: Ornithine carbamoyltransferase
controlled: Reaction179738
control type: ACTIVATION

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Argininosuccinic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Argininosuccinic acid

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Compound/PW C000095 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

ReactionCatalysis169619
type: Catalysis
controller: Carbamoyl-phosphate synthase 1, mitochondrial
controlled: Reaction179737
control type: ACTIVATION

ReactionCatalysis169618
type: Catalysis
controller: Glutamine synthetase
controlled: 6.3.1.2
control type: ACTIVATION

ReactionCatalysis169617
type: Catalysis
controller: Glutaminase a
controlled: Reaction179735
control type: ACTIVATION

ReactionCatalysis169616
type: Catalysis
controller: Glutamate dehydrogenase 1a
controlled: Reaction179734
control type: ACTIVATION

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

ReactionCatalysis169615
type: Catalysis
controller: N-acetylglutamate synthase, mitochondrial
controlled: 2.3.1.1
control type: ACTIVATION

ReactionCatalysis169614
type: Catalysis
controller: Si:ch211-217a12.1
controlled: Reaction179732
control type: ACTIVATION

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

ReactionCatalysis169613
type: Catalysis
controller: Aspartate aminotransferase
controlled: Reaction179731
control type: ACTIVATION

L-Alanine
type: SmallMolecule
entity reference: L-Alanine

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

Compound/PW C000140 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ornithine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 970
type: UnificationXref
id: 970
db: PubChem-compound

ChemicalStructure/PW C000088
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)\C=C\C(O)=O

Reference/PathWhiz PW122457
type: UnificationXref
id: PW122457
db: PathWhiz

Compound/PW C000200 Extracellular Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: Urea
stoichiometric coefficient: 1.0

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChEBI CHEBI 12575
type: UnificationXref
id: CHEBI:12575
db: ChEBI

Oxalacetic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000223
xref: Reference/CAS 328-42-7
xref: Reference/ChEBI CHEBI 30744
xref: Reference/BioCyc OXALACETIC ACID
xref: Reference/ChemSpider 945
xref: Reference/PubChem-compound 970
xref: Reference/KEGG Compound C00036
chemical formula: C4H4O5
molecular weight: 132.00587
structure: ChemicalStructure/PW C000148

Argininosuccinate lyase
type: Protein
cellular location: Cytoplasm
entity reference: Argininosuccinate lyase

Compound/PW C000200 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Urea
stoichiometric coefficient: 1.0

NADH
type: SmallMolecule
entity reference: NADH

Compound/PW C000123 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 21883788
type: UnificationXref
id: 21883788
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Nitric oxide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Nitric oxide

Argininosuccinic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C03406
xref: Reference/ChemSpider 16059
xref: Reference/HMDB HMDB0000052
xref: Reference/PubChem-compound 16950
xref: Reference/CAS 2387-71-5
xref: Reference/ChEBI CHEBI 15682
chemical formula: C10H18N4O6
molecular weight: 290.12262
structure: ChemicalStructure/PW C000036

Ammonia
type: SmallMoleculeReference
xref: Reference/BioCyc AMMONIA
xref: Reference/CAS 7664-41-7
xref: Reference/HMDB HMDB0000051
xref: Reference/PubChem-compound 222
xref: Reference/KEGG Compound C00014
xref: Reference/ChEBI CHEBI 16134
xref: Reference/ChemSpider 217
chemical formula: H3N
molecular weight: 17.026548
structure: ChemicalStructure/PW C000035

Reference/CAS 57-13-6
type: UnificationXref
id: 57-13-6
db: CAS

L-Arginine
type: SmallMoleculeReference
xref: Reference/BioCyc ARG
xref: Reference/ChEBI CHEBI 16467
xref: Reference/CAS 74-79-3
xref: Reference/KEGG Compound C00062
xref: Reference/ChemSpider 6082
xref: Reference/PubChem-compound 28782
xref: Reference/HMDB HMDB0000517
chemical formula: C6H14N4O2
molecular weight: 174.11168
structure: ChemicalStructure/PW C000396

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Compound/PW C000723 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Citrulline
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6992098
type: UnificationXref
id: 6992098
db: PubChem-compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/UniProt Q7T2P7
type: UnificationXref
id: Q7T2P7
db: UniProt

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Compound/PW C000123 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Citrulline
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Citrulline

L-Aspartic acid
type: SmallMolecule
cellular location: Mitochondrion
entity reference: L-Aspartic acid

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Ammonia
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Ammonia

Reference/UniProt Q7ZWF5
type: UnificationXref
id: Q7ZWF5
db: UniProt

Reference/CAS 328-42-7
type: UnificationXref
id: 328-42-7
db: CAS

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/ChEBI CHEBI 15729
type: UnificationXref
id: CHEBI:15729
db: ChEBI

Reference/UniProt Q66I24
type: UnificationXref
id: Q66I24
db: UniProt

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Ammonia
type: SmallMolecule
entity reference: Ammonia

L-Arginine
type: SmallMolecule
entity reference: L-Arginine
name: SubPathwayInput

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/ChemSpider 272
type: UnificationXref
id: 272
db: ChemSpider

Ornithine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Ornithine

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/CAS 70-26-8
type: UnificationXref
id: 70-26-8
db: CAS

Aspartate aminotransferase
type: Protein
cellular location: Mitochondrion
entity reference: Aspartate aminotransferase

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 6026
type: UnificationXref
id: 6026
db: ChemSpider

Compound/PW C000862 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbamoyl phosphate
stoichiometric coefficient: 1.0

Urea transporter
type: Protein
entity reference: Urea transporter

Ornithine
type: SmallMolecule
entity reference: Ornithine
name: SubPathwayInput

Adenosine triphosphate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Adenosine triphosphate

ChemicalStructure/PW C000200
type: ChemicalStructure
structure format: SMILES
structure data: NC(N)=O

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Ornithine
type: SmallMoleculeReference
xref: Reference/CAS 70-26-8
xref: Reference/HMDB HMDB0000214
xref: Reference/PubChem-compound 6262
xref: Reference/KEGG Compound C00077
xref: Reference/BioCyc L-ORNITHINE
xref: Reference/ChemSpider 6026
xref: Reference/ChEBI CHEBI 15729
chemical formula: C5H12N2O2
molecular weight: 132.08987
structure: ChemicalStructure/PW C000140

Reference/UniProt E9QHD9
type: UnificationXref
id: E9QHD9
db: UniProt

TransportCatalysis1521
type: Catalysis
controller: Urea transporter
controlled: Transport10352
control type: ACTIVATION

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/ChEBI CHEBI 16977
type: UnificationXref
id: CHEBI:16977
db: ChEBI

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Compound/PW C001867 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Nitric oxide
stoichiometric coefficient: 2.0

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Reference/ChemSpider 217
type: UnificationXref
id: 217
db: ChemSpider

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Glutaminase a
type: Protein
entity reference: Glutaminase a

Glutamate dehydrogenase 1a
type: Protein
entity reference: Glutamate dehydrogenase 1a

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Water
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Water

N-acetylglutamate synthase, mitochondrial
type: Protein
entity reference: N-acetylglutamate synthase, mitochondrial

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Si:ch211-217a12.1
type: Protein
entity reference: Si:ch211-217a12.1

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/HMDB HMDB0000214
type: UnificationXref
id: HMDB0000214
db: HMDB

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Glutamine synthetase
type: Protein
entity reference: Glutamine synthetase

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Ornithine
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Ornithine

Reference/UniProt Q533H0
type: UnificationXref
id: Q533H0
db: UniProt

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc ACETYL-GLU
type: UnificationXref
id: ACETYL-GLU
db: BioCyc

Compound/PW C000723 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Citrulline
stoichiometric coefficient: 3.0

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Reference/HMDB HMDB0000223
type: UnificationXref
id: HMDB0000223
db: HMDB

ChemicalStructure/PW C000140
type: ChemicalStructure
structure format: SMILES
structure data: NCCC[C@H](N)C(O)=O

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Fumaric acid
type: SmallMolecule
entity reference: Fumaric acid
name: SubPathwayInput

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 7664-41-7
type: UnificationXref
id: 7664-41-7
db: CAS

Fumaric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000134
xref: Reference/ChemSpider 10197150
xref: Reference/CAS 110-17-8
xref: Reference/PubChem-compound 21883788
xref: Reference/KEGG Compound C00122
xref: Reference/BioCyc FUM
xref: Reference/ChEBI CHEBI 18012
chemical formula: C4H4O4
molecular weight: 116.010956
structure: ChemicalStructure/PW C000088

Oxygen
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Oxygen

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

ChemicalStructure/PW C000105
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](N)C(O)=O

Reference/PubChem-compound 5950
type: UnificationXref
id: 5950
db: PubChem-compound

Reference/PubChem-compound 222
type: UnificationXref
id: 222
db: PubChem-compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/ChemSpider 6082
type: UnificationXref
id: 6082
db: ChemSpider

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/CAS 1188-37-0
type: UnificationXref
id: 1188-37-0
db: CAS

Nitric oxide synthase
type: Protein
cellular location: Cytoplasm
entity reference: Nitric oxide synthase

Compound/PW C000140 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ornithine
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Compound/PW C001034 Mitochondrion/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 2.0

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 16059
type: UnificationXref
id: 16059
db: ChemSpider

3.5.3.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000396 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000140 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000200 Cytoplasm/Stoichiometry/1.0
right: Ornithine
right: Urea
spontaneous: false
EC number: 3.5.3.1
left: L-Arginine
left: Water
name: L-Arginine + Water → Ornithine + Urea
conversion direction: LEFT_TO_RIGHT

Reaction179742
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000036 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000396 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088 Cytoplasm/Stoichiometry/1.0
right: Fumaric acid
right: L-Arginine
spontaneous: false
left: Argininosuccinic acid
name: Argininosuccinic acid → Fumaric acid + L-Arginine
conversion direction: LEFT_TO_RIGHT

6.3.4.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000036 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000723 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000123 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032 Cytoplasm/Stoichiometry/1.0
right: Adenosine monophosphate
right: Argininosuccinic acid
right: Pyrophosphate
spontaneous: false
EC number: 6.3.4.5
left: L-Aspartic acid
left: Citrulline
left: Adenosine triphosphate
name: Adenosine triphosphate + Citrulline + L-Aspartic acid → Adenosine monophosphate + Argininosuccinic acid + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000723
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCCNC(N)=O)C(O)=O

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/ChEBI CHEBI 15682
type: UnificationXref
id: CHEBI:15682
db: ChEBI

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Compound/PW C000146 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 3.0

Compound/PW C000396 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Arginine
stoichiometric coefficient: 1.0

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Urea
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Urea

2.3.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000888/Stoichiometry/1.0
right: Coenzyme A
right: N-Acetyl-L-glutamic acid
spontaneous: false
EC number: 2.3.1.1
left: L-Glutamic acid
left: Acetyl-CoA
name: Acetyl-CoA + L-Glutamic acid → Coenzyme A + N-Acetyl-L-glutamic acid
conversion direction: LEFT_TO_RIGHT

Reaction179732
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000105/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
right: L-Glutamic acid
right: Pyruvic acid
spontaneous: false
left: Oxoglutaric acid
left: L-Alanine
name: L-Alanine + Oxoglutaric acid → L-Glutamic acid + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reaction179731
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000148 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Mitochondrion/Stoichiometry/1.0
right: L-Glutamic acid
right: Oxalacetic acid
spontaneous: false
left: L-Aspartic acid
left: Oxoglutaric acid
name: L-Aspartic acid + Oxoglutaric acid → L-Glutamic acid + Oxalacetic acid
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc CARBAMOYL-P
type: UnificationXref
id: CARBAMOYL-P
db: BioCyc

Reaction179737
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001034 Mitochondrion/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001316 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Mitochondrion/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000035 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000862 Mitochondrion/Stoichiometry/1.0
right: Carbamoyl phosphate
right: Adenosine diphosphate
right: Phosphate
spontaneous: false
left: Carbon dioxide
left: Adenosine triphosphate
left: Ammonia
left: Water
name: 2 Adenosine triphosphate + Ammonia + Carbon dioxide + Water → 2 Adenosine diphosphate + Carbamoyl phosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

6.3.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035/Stoichiometry/1.0
right: Adenosine diphosphate
right: L-Glutamine
right: Phosphate
spontaneous: false
EC number: 6.3.1.2
left: L-Glutamic acid
left: Ammonia
left: Adenosine triphosphate
name: Adenosine triphosphate + Ammonia + L-Glutamic acid → Adenosine diphosphate + L-Glutamine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reaction179735
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035/Stoichiometry/1.0
right: L-Glutamic acid
right: Ammonia
spontaneous: false
left: Water
left: L-Glutamine
name: L-Glutamine + Water → Ammonia + L-Glutamic acid
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reaction179734
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035/Stoichiometry/1.0
right: NADH
right: Oxoglutaric acid
right: Ammonia
right: Hydrogen Ion
spontaneous: false
left: L-Glutamic acid
left: Water
left: NAD
name: L-Glutamic acid + NAD + Water ↔ Ammonia + Hydrogen Ion + NADH + Oxoglutaric acid
conversion direction: REVERSIBLE

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Compound/PW C000134 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/BioCyc NITRIC-OXIDE
type: UnificationXref
id: NITRIC-OXIDE
db: BioCyc

Carbon dioxide
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Carbon dioxide

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C000862
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)OP(O)(O)=O

Danio rerio
type: BioSource
xref: Reference/TAXONOMY 7955

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

1.14.13.39
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C000396 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001065 Cytoplasm/Stoichiometry/4.0
participant stoichiometry: Compound/PW C000143 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C001867 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000723 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/4.0
right: Citrulline
right: Water
right: Nitric oxide
right: NADP
spontaneous: false
EC number: 1.14.13.39
left: Oxygen
left: Hydrogen Ion
left: L-Arginine
left: NADPH
name: 3 Hydrogen Ion + 2 L-Arginine + 3 NADPH + 4 Oxygen ↔ 3 Citrulline + 3 NADP + 2 Nitric oxide + 4 Water
conversion direction: REVERSIBLE

Reaction179738
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000723 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000140 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000862 Mitochondrion/Stoichiometry/1.0
right: Phosphate
right: Citrulline
spontaneous: false
left: Carbamoyl phosphate
left: Ornithine
name: Carbamoyl phosphate + Ornithine → Citrulline + Phosphate
conversion direction: LEFT_TO_RIGHT

NADPH
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NADPH

Compound/PW C000036 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Argininosuccinic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C000396 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: L-Arginine
stoichiometric coefficient: 2.0

Reference/PubChem-compound 28782
type: UnificationXref
id: 28782
db: PubChem-compound

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/KEGG Compound C00624
type: UnificationXref
id: C00624
db: KEGG Compound

L-Arginine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Arginine

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/PubChem-compound 145068
type: UnificationXref
id: 145068
db: PubChem-compound

ChemicalStructure/PW C000888
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)N[C@@H](CCC(O)=O)C(O)=O

Reference/UniProt Q7SY44
type: UnificationXref
id: Q7SY44
db: UniProt

Compound/PW C001420 Cytoplasm/Stoichiometry/4.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 4.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1176
type: UnificationXref
id: 1176
db: PubChem-compound

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Compound/PW C000032 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/PubChem-compound 278
type: UnificationXref
id: 278
db: PubChem-compound

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/ChEBI CHEBI 16467
type: UnificationXref
id: CHEBI:16467
db: ChEBI

Reference/ChEBI CHEBI 16349
type: UnificationXref
id: CHEBI:16349
db: ChEBI

ChemicalStructure/PW C001867
type: ChemicalStructure
structure format: SMILES
structure data: [N]=O

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Compound/PW C000723 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Citrulline
stoichiometric coefficient: 1.0

Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17672
type: UnificationXref
id: CHEBI:17672
db: ChEBI

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/ChEBI CHEBI 30744
type: UnificationXref
id: CHEBI:30744
db: ChEBI

Compound/PW C000414 Mitochondrion/Stoichiometry/2.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 2.0

Carbamoyl-phosphate synthase 1, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Carbamoyl-phosphate synthase 1, mitochondrial

Ornithine carbamoyltransferase
type: Protein
cellular location: Mitochondrion
entity reference: Ornithine carbamoyltransferase

Compound/PW C000148 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxalacetic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 185
type: UnificationXref
id: 185
db: PubChem-compound

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

Compound/PW C001104 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00533
type: UnificationXref
id: C00533
db: KEGG Compound

SubPathwayInteraction110099
type: Interaction
name: SubPathwayReaction
name: SubPathway110099Reaction
participant: Urea

SubPathwayInteraction110098
type: Interaction
name: SubPathway110098Reaction
name: SubPathwayReaction
participant: Ornithine
participant: L-Arginine

SubPathwayInteraction110097
type: Interaction
name: SubPathway110097Reaction
name: SubPathwayReaction
participant: L-Arginine

Reference/UniProt A7WK81
type: UnificationXref
id: A7WK81
db: UniProt

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/CAS 74-79-3
type: UnificationXref
id: 74-79-3
db: CAS

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/HMDB HMDB0000517
type: UnificationXref
id: HMDB0000517
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

SubPathwayInteraction110096
type: Interaction
name: SubPathwayReaction
name: SubPathway110096Reaction
participant: Fumaric acid

Extracellular Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0031012

SubPathwayInteraction110095
type: Interaction
name: SubPathway110095Reaction
name: SubPathwayReaction
participant: L-Aspartic acid

SubPathwayInteraction110094
type: Interaction
name: SubPathwayReaction
name: SubPathway110094Reaction
participant: Carbamoyl phosphate

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

SubPathwayInteraction110093
type: Interaction
name: SubPathway110093Reaction
name: SubPathwayReaction
participant: Carbamoyl phosphate

Reference/UniProt E7FCP8
type: UnificationXref
id: E7FCP8
db: UniProt

SubPathwayInteraction110090
type: Interaction
name: SubPathwayReaction
name: SubPathway110090Reaction
participant: Oxoglutaric acid

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/BioCyc L-ORNITHINE
type: UnificationXref
id: L-ORNITHINE
db: BioCyc

Reference/ChemSpider 180
type: UnificationXref
id: 180
db: ChemSpider