3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (Hydroxymethylglutaricaciduria)
3-hydroxy-3-methylglutaryl coenzyme A synthase
Synthesis and Degradation of Ketone Bodies
Succinyl-CoA:3-ketoacid-coenzyme A transferase
Acetoacetic acid + Hydrogen Ion + NADH ↔ (R)-3-Hydroxybutyric acid + NAD
2 Acetyl-CoA ↔ Acetoacetyl-CoA + Coenzyme A
Acetoacetyl-CoA + Succinic acid ↔ Acetoacetic acid + Succinyl-CoA
3-Hydroxy-3-methylglutaryl-CoA → Acetoacetic acid + Acetyl-CoA
Acetoacetyl-CoA + Acetyl-CoA + Water → 3-Hydroxy-3-methylglutaryl-CoA + Coenzyme A