Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/ChEBI CHEBI 83813
type: UnificationXref
id: CHEBI: 83813
db: ChEBI

a 2-oxo carboxylate
type: SmallMolecule
cellular location: Chloroplast
entity reference: a 2-oxo carboxylate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Glucosinolate biosynthesis from homomethionine
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110190
pathway component: SubPathwayInteraction110190
name: SubPathway

3-isopropylmalate dehydratase small subunit 1
type: ProteinReference
xref: Reference/UniProt Q9ZW84
organism: Arabidopsis thaliana

Aliphatic glucosinolate biosynthesis, side chain elongation cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway110191
pathway component: SubPathwayInteraction110191
name: SubPathway

Hydrogen Ion
type: SmallMolecule
cellular location: Chloroplast
entity reference: Hydrogen Ion

Compound/PW C000721 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Protein/11179 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-isopropylmalate dehydratase large subunit
stoichiometric coefficient: 1.0

Compound/Generic553 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: a proteinogenic amino acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6137
type: UnificationXref
id: 6137
db: PubChem-compound

Reference/PubChem-compound 473
type: UnificationXref
id: 473
db: PubChem-compound

Compound/PW C040034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

a proteinogenic amino acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: a proteinogenic amino acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Compound/Generic553 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: a proteinogenic amino acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C17210
type: UnificationXref
id: C17210
db: KEGG Compound

Reference/KEGG Compound C17211
type: UnificationXref
id: C17211
db: KEGG Compound

Reference/KEGG Compound C17212
type: UnificationXref
id: C17212
db: KEGG Compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C000548
type: ChemicalStructure
structure format: SMILES
structure data: CSCC[C@H](N)C(O)=O

Compound/PW C000940 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/PubChem-compound 90659289
type: UnificationXref
id: 90659289
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0009507
type: UnificationXref
id: GO:0009507
db: GENE ONTOLOGY

Reference/UniProt Q9M401
type: UnificationXref
id: Q9M401
db: UniProt

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

a 2-oxo carboxylate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00161

a proteinogenic amino acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 83813

Compound/PW C104712 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-[(2'-methylsulfanyl)ethyl]malate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

L-homomethionine
type: SmallMolecule
entity reference: L-homomethionine
name: SubPathwayInput

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW122497
type: UnificationXref
id: PW122497
db: PathWhiz

Reference/KEGG Compound C17213
type: UnificationXref
id: C17213
db: KEGG Compound

Reference/PubChem-compound 122164863
type: UnificationXref
id: 122164863
db: PubChem-compound

Protein/22818 Chloroplast/Stoichiometry/2.0
type: Stoichiometry
physical entity: 3-isopropylmalate dehydrogenase 1, chloroplastic
stoichiometric coefficient: 2.0

3-isopropylmalate dehydratase large subunit
type: ProteinReference
xref: Reference/UniProt Q94AR8
organism: Arabidopsis thaliana

2-[(2'-methylsulfanyl)ethyl]maleate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-[(2'-methylsulfanyl)ethyl]maleate

Branched-chain-amino-acid aminotransferase 3, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9M401
organism: Arabidopsis thaliana

Reference/PubChem-compound 25203687
type: UnificationXref
id: 25203687
db: PubChem-compound

Carbon dioxide
type: SmallMolecule
cellular location: Chloroplast
entity reference: Carbon dioxide

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

3-isopropylmalate dehydratase small subunit 1
type: Protein
cellular location: Chloroplast
entity reference: 3-isopropylmalate dehydratase small subunit 1

Reference/HMDB HMDB0000696
type: UnificationXref
id: HMDB0000696
db: HMDB

3-[(2'-methylsulfanyl)ethyl]malate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 3-[(2'-methylsulfanyl)ethyl]malate

5-(methylsulfanyl)-2-oxopentanoate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 5-(methylsulfanyl)-2-oxopentanoate

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

NAD
type: SmallMolecule
cellular location: Chloroplast
entity reference: NAD

a proteinogenic amino acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: a proteinogenic amino acid

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/HMDB HMDB0001553
type: UnificationXref
id: HMDB0001553
db: HMDB

Compound/PW C001099 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

ReactionCatalysis169907
type: Catalysis
controller: 3-isopropylmalate dehydrogenase 1, chloroplastic
controlled: 1.1.1.85
control type: ACTIVATION

ReactionCatalysis169905
type: Catalysis
controller: Branched-chain-amino-acid aminotransferase 3, chloroplastic
controlled: Reaction180051
control type: ACTIVATION

Reference/ChEBI CHEBI 134631
type: UnificationXref
id: CHEBI:134631
db: ChEBI

Compound/Generic552 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: a 2-oxo carboxylate
stoichiometric coefficient: 1.0

ReactionCatalysis169903
type: Catalysis
controller: 2-(n'-methylthio)alkylmalate dehydratase
controlled: 4.2.1.33
control type: ACTIVATION

ReactionCatalysis169902
type: Catalysis
controller: 2-(n'-methylthio)alkylmalate dehydratase
controlled: 4.2.1.33
control type: ACTIVATION

ReactionCatalysis169901
type: Catalysis
controller: Methylthioalkylmalate synthase 3, chloroplastic
controlled: 2.3.3.17
control type: ACTIVATION

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H28N7O14P2
molecular weight: 664.11694
structure: ChemicalStructure/PW C000721

Methionine aminotransferase BCAT4
type: Protein
cellular location: Cytoplasm
entity reference: Methionine aminotransferase BCAT4

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Compound/PW C104715 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-homomethionine
stoichiometric coefficient: 1.0

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/UniProt Q9LE06
type: UnificationXref
id: Q9LE06
db: UniProt

Compound/PW C000548 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Methionine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 123131525
type: UnificationXref
id: 123131525
db: PubChem-compound

a 2-oxo carboxylate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: a 2-oxo carboxylate

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Acetyl-CoA
type: SmallMolecule
cellular location: Chloroplast
entity reference: Acetyl-CoA

Reference/PubChem-compound 25203353
type: UnificationXref
id: 25203353
db: PubChem-compound

Reference/BioCyc MET
type: UnificationXref
id: MET
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Water
type: SmallMolecule
cellular location: Chloroplast
entity reference: Water

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/UniProt Q94AR8
type: UnificationXref
id: Q94AR8
db: UniProt

Reference/ChemSpider 460
type: UnificationXref
id: 460
db: ChemSpider

Reference/UniProt Q9FMT1
type: UnificationXref
id: Q9FMT1
db: UniProt

Reference/UniProt Q9FN52
type: UnificationXref
id: Q9FN52
db: UniProt

L-Methionine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000696
xref: Reference/ChEBI CHEBI 16643
xref: Reference/KEGG Compound C00073
xref: Reference/CAS 63-68-3
xref: Reference/BioCyc MET
xref: Reference/PubChem-compound 6137
xref: Reference/ChemSpider 5907
chemical formula: C5H11NO2S
molecular weight: 149.05106
structure: ChemicalStructure/PW C000548

Compound/PW C104713 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate
stoichiometric coefficient: 1.0

Methylthioalkylmalate synthase 3, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Methylthioalkylmalate synthase 3, chloroplastic

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Compound/PW C001195 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Oxo-4-methylthiobutanoic acid
stoichiometric coefficient: 1.0

NADH
type: SmallMolecule
cellular location: Chloroplast
entity reference: NADH

Reaction180050
type: BiochemicalReaction
participant stoichiometry: Compound/PW C104713 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104714 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: 5-(methylsulfanyl)-2-oxopentanoate
right: Carbon dioxide
spontaneous: true
left: Hydrogen Ion
left: 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate
name: 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate + Hydrogen Ion → 5-(methylsulfanyl)-2-oxopentanoate + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Protein/11779 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-isopropylmalate dehydratase small subunit 1
stoichiometric coefficient: 1.0

Reaction180051
type: BiochemicalReaction
participant stoichiometry: Compound/Generic552 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104715 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/Generic553 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104714 Chloroplast/Stoichiometry/1.0
right: L-homomethionine
right: a 2-oxo carboxylate
spontaneous: false
left: a proteinogenic amino acid
left: 5-(methylsulfanyl)-2-oxopentanoate
name: 5-(methylsulfanyl)-2-oxopentanoate + a proteinogenic amino acid ↔ L-homomethionine + a 2-oxo carboxylate
conversion direction: REVERSIBLE

Reference/UniProt Q9ZW84
type: UnificationXref
id: Q9ZW84
db: UniProt

4.2.1.33
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104716 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104712 Chloroplast/Stoichiometry/1.0
right: 3-[(2'-methylsulfanyl)ethyl]malate
spontaneous: false
EC number: 4.2.1.33
left: Water
left: 2-[(2'-methylsulfanyl)ethyl]maleate
name: 2-[(2'-methylsulfanyl)ethyl]maleate + Water ↔ 3-[(2'-methylsulfanyl)ethyl]malate
conversion direction: REVERSIBLE

4.2.1.33
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104711 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104716 Chloroplast/Stoichiometry/1.0
right: Water
right: 2-[(2'-methylsulfanyl)ethyl]maleate
spontaneous: false
EC number: 4.2.1.33
left: 2-[(2'-methylsulfanyl)ethyl]malate
name: 2-[(2'-methylsulfanyl)ethyl]malate ↔ 2-[(2'-methylsulfanyl)ethyl]maleate + Water
conversion direction: REVERSIBLE

Branched-chain-amino-acid aminotransferase 3, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Branched-chain-amino-acid aminotransferase 3, chloroplastic

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

1.1.1.85
type: BiochemicalReaction
participant stoichiometry: Compound/PW C104713 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104712 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: Hydrogen Ion
right: NADH
right: 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate
spontaneous: false
EC number: 1.1.1.85
left: 3-[(2'-methylsulfanyl)ethyl]malate
left: NAD
name: 3-[(2'-methylsulfanyl)ethyl]malate + NAD → 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/PubChem-compound 25203496
type: UnificationXref
id: 25203496
db: PubChem-compound

Compound/PW C001420 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

2-(n'-methylthio)alkylmalate dehydratase
type: Complex
component stoichiometry: Protein/11179 Chloroplast/Stoichiometry/1.0
component stoichiometry: Protein/11779 Chloroplast/Stoichiometry/1.0
cellular location: Chloroplast
component: 3-isopropylmalate dehydratase small subunit 1
component: 3-isopropylmalate dehydratase large subunit

3-isopropylmalate dehydrogenase 1, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: 3-isopropylmalate dehydrogenase 1, chloroplastic

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

2.3.3.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C104711 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001195 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: 2-[(2'-methylsulfanyl)ethyl]malate
right: Hydrogen Ion
right: Coenzyme A
spontaneous: false
EC number: 2.3.3.17
left: Acetyl-CoA
left: Water
left: 2-Oxo-4-methylthiobutanoic acid
name: 2-Oxo-4-methylthiobutanoic acid + Acetyl-CoA + Water → 2-[(2'-methylsulfanyl)ethyl]malate + Coenzyme A + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

3-isopropylmalate dehydrogenase 1, chloroplastic
type: Complex
component stoichiometry: Protein/22818 Chloroplast/Stoichiometry/2.0
cellular location: Chloroplast
component: 3-isopropylmalate dehydrogenase 1, chloroplastic

2.6.1.88
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001195 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000548 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic553 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/Generic552 Cytoplasm/Stoichiometry/1.0
right: 2-Oxo-4-methylthiobutanoic acid
right: a proteinogenic amino acid
spontaneous: false
EC number: 2.6.1.88
left: a 2-oxo carboxylate
left: L-Methionine
name: L-Methionine + a 2-oxo carboxylate → 2-Oxo-4-methylthiobutanoic acid + a proteinogenic amino acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C104711
type: ChemicalStructure
structure format: SMILES
structure data: CSCCC(O)(CC([O-])=O)C([O-])=O

3-isopropylmalate dehydratase large subunit
type: Protein
cellular location: Chloroplast
entity reference: 3-isopropylmalate dehydratase large subunit

ChemicalStructure/PW C104713
type: ChemicalStructure
structure format: SMILES
structure data: CSCCC(C([O-])=O)C(=O)C([O-])=O

ChemicalStructure/PW C104712
type: ChemicalStructure
structure format: SMILES
structure data: CSCCC(C(O)C([O-])=O)C([O-])=O

ChemicalStructure/PW C104715
type: ChemicalStructure
structure format: SMILES
structure data: CSCCC[C@H]([N+])C([O-])=O

ChemicalStructure/PW C104714
type: ChemicalStructure
structure format: SMILES
structure data: CSCCCC(=O)C([O-])=O

Reference/BioCyc CPD-479
type: UnificationXref
id: CPD-479
db: BioCyc

ChemicalStructure/PW C104716
type: ChemicalStructure
structure format: SMILES
structure data: CSCC\C(=C\C([O-])=O)C([O-])=O

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

2-Oxo-4-methylthiobutanoic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 2-Oxo-4-methylthiobutanoic acid

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Compound/PW C001195 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Oxo-4-methylthiobutanoic acid
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Compound/Generic552 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: a 2-oxo carboxylate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

L-Methionine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Methionine

Reference/CAS 63-68-3
type: UnificationXref
id: 63-68-3
db: CAS

Reference/ChemSpider 5907
type: UnificationXref
id: 5907
db: ChemSpider

Reference/ChEBI CHEBI 16643
type: UnificationXref
id: CHEBI:16643
db: ChEBI

ReactionCatalysis169899
type: Catalysis
controller: Methionine aminotransferase BCAT4
controlled: 2.6.1.88
control type: ACTIVATION

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C001144 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

2-Oxo-4-methylthiobutanoic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001553
xref: Reference/KEGG Compound C01180
xref: Reference/BioCyc CPD-479
xref: Reference/CAS 583-92-6
xref: Reference/ChEBI CHEBI 33574
xref: Reference/ChemSpider 460
xref: Reference/PubChem-compound 473
chemical formula: C5H8O3S
molecular weight: 148.01941
structure: ChemicalStructure/PW C001195

Reference/KEGG Compound C00073
type: UnificationXref
id: C00073
db: KEGG Compound

Reference/SMPDB SMP0121204
type: UnificationXref
id: SMP0121204
db: SMPDB

L-homomethionine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 134631
xref: Reference/PubChem-compound 90659289
xref: Reference/KEGG Compound C17213
chemical formula: C6H10NO2S
molecular weight: 160.04323
structure: ChemicalStructure/PW C104715

2-[(2'-methylsulfanyl)ethyl]maleate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 122164863
chemical formula: C7H8O4S
molecular weight: 188.01543
structure: ChemicalStructure/PW C104716

2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 123131525
chemical formula: C7H8O5S
molecular weight: 204.01035
structure: ChemicalStructure/PW C104713

5-(methylsulfanyl)-2-oxopentanoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58815
xref: Reference/KEGG Compound C17211
xref: Reference/PubChem-compound 25203687
chemical formula: C6H9O3S
molecular weight: 161.02779
structure: ChemicalStructure/PW C104714

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

2-[(2'-methylsulfanyl)ethyl]malate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C17210
xref: Reference/ChEBI CHEBI 58816
xref: Reference/PubChem-compound 25203353
chemical formula: C7H10O5S
molecular weight: 206.02599
structure: ChemicalStructure/PW C104711

3-[(2'-methylsulfanyl)ethyl]malate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C17212
xref: Reference/PubChem-compound 25203496
xref: Reference/ChEBI CHEBI 133497
chemical formula: C7H10O5S
molecular weight: 206.02599
structure: ChemicalStructure/PW C104712

L-homomethionine
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-homomethionine

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

2-[(2'-methylsulfanyl)ethyl]malate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-[(2'-methylsulfanyl)ethyl]malate

Reference/CAS 583-92-6
type: UnificationXref
id: 583-92-6
db: CAS

2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-[2-(methylsulfanyl)ethyl]-3-oxobutanedioate

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Chloroplast
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0009507

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Compound/PW C104714 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-(methylsulfanyl)-2-oxopentanoate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 58815
type: UnificationXref
id: CHEBI:58815
db: ChEBI

Reference/KEGG Compound C01180
type: UnificationXref
id: C01180
db: KEGG Compound

Compound/PW C104711 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-[(2'-methylsulfanyl)ethyl]malate
stoichiometric coefficient: 1.0

SubPathwayInteraction110191
type: Interaction
name: SubPathway110191Reaction
name: SubPathwayReaction
participant: L-homomethionine

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

SubPathwayInteraction110190
type: Interaction
name: SubPathwayReaction
name: SubPathway110190Reaction
participant: L-homomethionine

Compound/PW C001316 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 58816
type: UnificationXref
id: CHEBI:58816
db: ChEBI

ChemicalStructure/PW C001195
type: ChemicalStructure
structure format: SMILES
structure data: CSCCC(=O)C(O)=O

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/ChEBI CHEBI 33574
type: UnificationXref
id: CHEBI:33574
db: ChEBI

Reference/KEGG Compound C00161
type: UnificationXref
id: C00161
db: KEGG Compound

Coenzyme A
type: SmallMolecule
cellular location: Chloroplast
entity reference: Coenzyme A

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

2-Oxo-4-methylthiobutanoic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: 2-Oxo-4-methylthiobutanoic acid

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

L-Homomethionine Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/2124970
pathway order: PathwayEnzymeReaction/2124981
pathway order: PathwayEnzymeReaction/2124982
pathway order: PathwayEnzymeReaction/2124953
pathway order: PathwaySubPathway/110191
pathway order: PathwayEnzymeReaction/2124967
pathway order: PathwaySubPathway/110190
pathway order: PathwayEnzymeReaction/2124977
pathway order: PathwayEnzymeReaction/2124979
pathway component: ReactionCatalysis169905
pathway component: ReactionCatalysis169903
pathway component: ReactionCatalysis169902
pathway component: ReactionCatalysis169901
pathway component: 4.2.1.33
pathway component: ReactionCatalysis169899
pathway component: 1.1.1.85
pathway component: Glucosinolate biosynthesis from homomethionine
pathway component: Aliphatic glucosinolate biosynthesis, side chain elongation cycle
pathway component: 2.3.3.17
pathway component: 2.6.1.88
pathway component: Reaction180050
pathway component: ReactionCatalysis169907
pathway component: Reaction180051
xref: Reference/PathWhiz PW122497
xref: Reference/SMPDB SMP0121204
organism: Arabidopsis thaliana

Methylthioalkylmalate synthase 3, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9FN52
organism: Arabidopsis thaliana

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

3-isopropylmalate dehydrogenase 1, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9FMT1
organism: Arabidopsis thaliana

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Methionine aminotransferase BCAT4
type: ProteinReference
xref: Reference/UniProt Q9LE06
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/ChEBI CHEBI 133497
type: UnificationXref
id: CHEBI:133497
db: ChEBI

Compound/PW C104716 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-[(2'-methylsulfanyl)ethyl]maleate
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS