Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 35452
type: UnificationXref
id: CHEBI:35452
db: ChEBI

ReactionCatalysis176944
type: Catalysis
controller: Phosphomannomutase/phosphoglucomutase
controlled: 5.4.2.2
control type: ACTIVATION

Glucose-1-phosphate thymidylyltransferase
type: Protein
cellular location: Cytoplasm
entity reference: Glucose-1-phosphate thymidylyltransferase

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C000143 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/UniProt Q51559
type: UnificationXref
id: Q51559
db: UniProt

(3R)-3-Hydroxyacyl-[acyl-carrier protein]
type: Protein
cellular location: Inner Membrane
entity reference: (3R)-3-Hydroxyacyl-[acyl-carrier protein]

Rhamnosyltransferase 2
type: Protein
cellular location: Inner Membrane
entity reference: Rhamnosyltransferase 2

Reference/UniProt Q9HU24
type: UnificationXref
id: Q9HU24
db: UniProt

ChemicalStructure/PW C042658
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00688
type: UnificationXref
id: C00688
db: KEGG Compound

Reference/UniProt Q9HU23
type: UnificationXref
id: Q9HU23
db: UniProt

Glucose 1-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Glucose 1-phosphate

Reference/UniProt Q9HU22
type: UnificationXref
id: Q9HU22
db: UniProt

Reference/UniProt Q9HU21
type: UnificationXref
id: Q9HU21
db: UniProt

(3R)-3-Hydroxyacyl-[acyl-carrier protein]
type: ProteinReference
xref: Reference/KEGG Compound C01271
organism: BiologicalState189

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Compound/Generic582 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Di-rhamnolipid
stoichiometric coefficient: 1.0

Compound/Generic580 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: (3R)-(3-Hydroxyalkanoyloxy)alkanoate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00459
type: UnificationXref
id: C00459
db: KEGG Compound

Reference/ChemSpider 388455
type: UnificationXref
id: 388455
db: ChemSpider

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/ChemSpider 5743
type: UnificationXref
id: 5743
db: ChemSpider

Reference/CAS 365-08-2
type: UnificationXref
id: 365-08-2
db: CAS

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/HMDB HMDB0001401
type: UnificationXref
id: HMDB0001401
db: HMDB

Reference/PubChem-compound 64968
type: UnificationXref
id: 64968
db: PubChem-compound

Compound/PW C001035 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine 5'-triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439975
type: UnificationXref
id: 439975
db: PubChem-compound

ChemicalStructure/PW C001083
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00229
type: UnificationXref
id: C00229
db: KEGG Compound

Reference/PathWhiz PW002458
type: UnificationXref
id: PW002458
db: PathWhiz

Reference/PubChem-compound 164628
type: UnificationXref
id: 164628
db: PubChem-compound

Reference/ChemSpider 58493
type: UnificationXref
id: 58493
db: ChemSpider

Reference/KEGG Compound C00103
type: UnificationXref
id: C00103
db: KEGG Compound

ChemicalStructure/PW C002734
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Reference/PubChem-compound 439165
type: UnificationXref
id: 439165
db: PubChem-compound

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Compound/PW C001083 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucose 6-phosphate
stoichiometric coefficient: 1.0

Fatty Acid Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway112543
pathway component: SubPathwayInteraction112543
xref: Reference/SMPDB SMP0002360
xref: Reference/PathWhiz PW002458
name: SubPathway

Compound/PW C001024 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-D-glucose
stoichiometric coefficient: 1.0

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Mono-rhamnolipid
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Mono-rhamnolipid

[Acyl-carrier protein]
type: Protein
cellular location: Inner Membrane
entity reference: [Acyl-carrier protein]

Reference/ChemSpider 144320
type: UnificationXref
id: 144320
db: ChemSpider

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

dTDP
type: SmallMoleculeReference
xref: Reference/CAS 491-97-4
xref: Reference/ChemSpider 144320
xref: Reference/PubChem-compound 164628
xref: Reference/KEGG Compound C00363
xref: Reference/ChEBI CHEBI 18075
xref: Reference/HMDB HMDB0001274
xref: Reference/BioCyc TDP
chemical formula: C10H16N2O11P2
molecular weight: 402.02292
structure: ChemicalStructure/PW C000987

Reference/CAS 59-56-3
type: UnificationXref
id: 59-56-3
db: CAS

Reference/ChemSpider 388311
type: UnificationXref
id: 388311
db: ChemSpider

Rhamnosyltransferase chain B
type: ProteinReference
xref: Reference/UniProt Q9HYD1
organism: BiologicalState189

Rhamnosyltransferase 2
type: ProteinReference
xref: Reference/UniProt Q9I4K5
organism: BiologicalState189

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: dTDP-4-dehydro-6-deoxy-D-glucose

dTDP-4-dehydrorhamnose reductase
type: ProteinReference
xref: Reference/UniProt Q9HU23
organism: Pseudomonas aeruginosa

Compound/PW C000146 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

3-(3-Hydroxydecanoyloxy)decanoate synthase
type: ProteinReference
xref: Reference/UniProt Q51559
organism: BiologicalState189

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

dTDP-4-dehydrorhamnose 3,5-epimerase
type: ProteinReference
xref: Reference/UniProt Q9HU21
organism: Pseudomonas aeruginosa

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00363
type: UnificationXref
id: C00363
db: KEGG Compound

Reference/ChEBI CHEBI 35248
type: UnificationXref
id: CHEBI:35248
db: ChEBI

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/HMDB HMDB0060081
type: UnificationXref
id: HMDB0060081
db: HMDB

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/UniProt Q9I4K5
type: UnificationXref
id: Q9I4K5
db: UniProt

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

NADP
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NADP

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis176997
type: Catalysis
controller: Rhamnosyltransferase 2
controlled: 2.4.1.-
control type: ACTIVATION

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

dTDP-D-glucose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: dTDP-D-glucose

ReactionCatalysis176993
type: Catalysis
controller: dTDP-4-dehydrorhamnose 3,5-epimerase
controlled: 5.1.3.13
control type: ACTIVATION

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis176995
type: Catalysis
controller: 3-(3-Hydroxydecanoyloxy)decanoate synthase
controlled: 2.3.1.-
control type: ACTIVATION

Reference/BioCyc GLC-1-P
type: UnificationXref
id: GLC-1-P
db: BioCyc

ReactionCatalysis176996
type: Catalysis
controller: Rhamnosyltransferase chain B
controlled: 2.4.1.-
control type: ACTIVATION

ReactionCatalysis176992
type: Catalysis
controller: Glucose-1-phosphate thymidylyltransferase
controlled: 2.7.7.24
control type: ACTIVATION

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

[Acyl-carrier protein]
type: ProteinReference
xref: Reference/KEGG Compound C00229
organism: BiologicalState189

(3R)-(3-Hydroxyalkanoyloxy)alkanoate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: (3R)-(3-Hydroxyalkanoyloxy)alkanoate

Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/BioCyc TDP
type: UnificationXref
id: TDP
db: BioCyc

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/SMPDB SMP0002360
type: UnificationXref
id: SMP0002360
db: SMPDB

Reference/PubChem-compound 5958
type: UnificationXref
id: 5958
db: PubChem-compound

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

dTDP-D-glucose
type: SmallMoleculeReference
xref: Reference/ChemSpider 388455
xref: Reference/KEGG Compound C00842
xref: Reference/PubChem-compound 439324
xref: Reference/HMDB HMDB0001328
xref: Reference/CAS 2196-62-5
xref: Reference/ChEBI CHEBI 35248
xref: Reference/BioCyc DTDP-D-GLUCOSE
chemical formula: C16H26N2O16P2
molecular weight: 564.07574
structure: ChemicalStructure/PW C001024

Reference/HMDB HMDB0001328
type: UnificationXref
id: HMDB0001328
db: HMDB

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/UniProt Q9HYD1
type: UnificationXref
id: Q9HYD1
db: UniProt

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

ChemicalStructure/PW C001207
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P26276
type: UnificationXref
id: P26276
db: UniProt

dTDP-β-L-rhamnose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: dTDP-β-L-rhamnose

SubPathwayInteraction112543
type: Interaction
name: SubPathwayReaction
name: SubPathway112543Reaction
participant: (3R)-3-Hydroxyacyl-[acyl-carrier protein]

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Thymidine 5'-triphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00459
xref: Reference/CAS 365-08-2
xref: Reference/ChEBI CHEBI 18077
xref: Reference/ChemSpider 58493
xref: Reference/PubChem-compound 64968
xref: Reference/HMDB HMDB0001342
xref: Reference/BioCyc TTP
chemical formula: C10H17N2O14P3
molecular weight: 481.98926
structure: ChemicalStructure/PW C001035

dTDP-glucose 4,6-dehydratase
type: Protein
cellular location: Cytoplasm
entity reference: dTDP-glucose 4,6-dehydratase

dTDP-4-dehydro-β-L-rhamnose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 45868
xref: Reference/KEGG Compound C00688
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C044520

Reference/BioCyc TTP
type: UnificationXref
id: TTP
db: BioCyc

Reference/ChemSpider 388998
type: UnificationXref
id: 388998
db: ChemSpider

dTDP-4-dehydro-β-L-rhamnose
type: SmallMolecule
cellular location: Cytoplasm
entity reference: dTDP-4-dehydro-β-L-rhamnose

Reference/HMDB HMDB0001586
type: UnificationXref
id: HMDB0001586
db: HMDB

ChemicalStructure/PW C001024
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00092
xref: Reference/BioCyc GLC-6-P
xref: Reference/HMDB HMDB0001401
xref: Reference/PubChem-compound 5958
xref: Reference/ChemSpider 5743
xref: Reference/CAS 56-73-5
xref: Reference/ChEBI CHEBI 4170
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001083

Reference/HMDB HMDB0001342
type: UnificationXref
id: HMDB0001342
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0006354
type: UnificationXref
id: HMDB0006354
db: HMDB

Compound/PW C000987 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00842
type: UnificationXref
id: C00842
db: KEGG Compound

1.1.1.133
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002734 Cytoplasm/Stoichiometry/1.0
right: dTDP-β-L-rhamnose
right: NADP
spontaneous: false
EC number: 1.1.1.133
left: Hydrogen Ion
left: dTDP-4-dehydro-β-L-rhamnose
left: NADPH
name: Hydrogen Ion + NADPH + dTDP-4-dehydro-β-L-rhamnose → NADP + dTDP-β-L-rhamnose
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C03319
type: UnificationXref
id: C03319
db: KEGG Compound

dTDP-β-L-rhamnose
type: SmallMoleculeReference
xref: Reference/CAS 2147-59-3
xref: Reference/KEGG Compound C03319
xref: Reference/ChemSpider 388998
xref: Reference/ChEBI CHEBI 35452
xref: Reference/PubChem-compound 439975
xref: Reference/BioCyc DTDP-RHAMNOSE
xref: Reference/HMDB HMDB0006354
chemical formula: C16H26N2O15P2
molecular weight: 548.0809
structure: ChemicalStructure/PW C002734

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/BioCyc DTDP-RHAMNOSE
type: UnificationXref
id: DTDP-RHAMNOSE
db: BioCyc

ChemicalStructure/PW C001035
type: ChemicalStructure
structure format: SMILES

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

dTDP-4-dehydrorhamnose 3,5-epimerase
type: Protein
cellular location: Cytoplasm
entity reference: dTDP-4-dehydrorhamnose 3,5-epimerase

NADPH
type: SmallMolecule
cellular location: Cytoplasm
entity reference: NADPH

Compound/PW C044520 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-β-L-rhamnose
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

Reference/ChEBI CHEBI 16077
type: UnificationXref
id: CHEBI:16077
db: ChEBI

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Phosphomannomutase/phosphoglucomutase
type: ProteinReference
xref: Reference/UniProt P26276
organism: Pseudomonas aeruginosa

Reference/ChEBI CHEBI 4170
type: UnificationXref
id: CHEBI:4170
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

2.7.7.24
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001035 Cytoplasm/Stoichiometry/1.0
right: dTDP-D-glucose
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.24
left: Glucose 1-phosphate
left: Thymidine 5'-triphosphate
name: Glucose 1-phosphate + Thymidine 5'-triphosphate → Pyrophosphate + dTDP-D-glucose
conversion direction: LEFT_TO_RIGHT

5.1.3.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042658 Cytoplasm/Stoichiometry/1.0
right: dTDP-4-dehydro-β-L-rhamnose
spontaneous: false
EC number: 5.1.3.13
left: dTDP-4-dehydro-6-deoxy-D-glucose
name: dTDP-4-dehydro-6-deoxy-D-glucose ↔ dTDP-4-dehydro-β-L-rhamnose
conversion direction: REVERSIBLE

Compound/PW C002734 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-β-L-rhamnose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01271
type: UnificationXref
id: C01271
db: KEGG Compound

Reference/SMPDB SMP0122304
type: UnificationXref
id: SMP0122304
db: SMPDB

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060081
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C042658

dTDP-glucose 4,6-dehydratase
type: ProteinReference
xref: Reference/UniProt Q9HU24
organism: Pseudomonas aeruginosa

Reference/BioCyc DTDP-D-GLUCOSE
type: UnificationXref
id: DTDP-D-GLUCOSE
db: BioCyc

Reference/PathWhiz PW123614
type: UnificationXref
id: PW123614
db: PathWhiz

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Reference/BioCyc GLC-6-P
type: UnificationXref
id: GLC-6-P
db: BioCyc

Glucose-1-phosphate thymidylyltransferase
type: ProteinReference
xref: Reference/UniProt Q9HU22
organism: Pseudomonas aeruginosa

Reference/PubChem-compound 439324
type: UnificationXref
id: 439324
db: PubChem-compound

dTDP
type: SmallMolecule
cellular location: Inner Membrane
entity reference: dTDP

Compound/Generic581 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Mono-rhamnolipid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Rhamnolipid Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/2169009
pathway order: PathwayEnzymeReaction/2169010
pathway order: PathwayEnzymeReaction/2169013
pathway order: PathwayEnzymeReaction/2457543
pathway order: PathwayEnzymeReaction/2169012
pathway order: PathwayEnzymeReaction/2457542
pathway order: PathwayEnzymeReaction/2169011
pathway order: PathwayEnzymeReaction/2457541
pathway order: PathwaySubPathway/112543
pathway component: 1.1.1.133
pathway component: ReactionCatalysis173638
pathway component: ReactionCatalysis176907
pathway component: ReactionCatalysis176997
pathway component: ReactionCatalysis176944
pathway component: 2.7.7.24
pathway component: 5.1.3.13
pathway component: ReactionCatalysis176993
pathway component: ReactionCatalysis176995
pathway component: ReactionCatalysis176996
pathway component: Fatty Acid Biosynthesis
pathway component: ReactionCatalysis176992
pathway component: 2.3.1.-
pathway component: Reaction187052
pathway component: 2.4.1.-
pathway component: 5.4.2.2
xref: Reference/SMPDB SMP0122304
xref: Reference/PathWhiz PW123614
organism: Pseudomonas aeruginosa

BiologicalState189
type: BioSource
xref: Reference/TAXONOMY 4932
name: Saccharomyces cerevisiae

Reference/ChEBI CHEBI 18077
type: UnificationXref
id: CHEBI:18077
db: ChEBI

3-(3-Hydroxydecanoyloxy)decanoate synthase
type: Protein
cellular location: Inner Membrane
entity reference: 3-(3-Hydroxydecanoyloxy)decanoate synthase

Reference/ChEBI CHEBI 18075
type: UnificationXref
id: CHEBI:18075
db: ChEBI

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Protein/Generic203 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: (3R)-3-Hydroxyacyl-[acyl-carrier protein]
stoichiometric coefficient: 2.0

Pseudomonas aeruginosa
type: BioSource
xref: Reference/TAXONOMY 287

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 45868
type: UnificationXref
id: CHEBI:45868
db: ChEBI

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

ReactionCatalysis173638
type: Catalysis
controller: dTDP-4-dehydrorhamnose reductase
controlled: 1.1.1.133
control type: ACTIVATION

ReactionCatalysis176907
type: Catalysis
controller: dTDP-glucose 4,6-dehydratase
controlled: Reaction187052
control type: ACTIVATION

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001586
xref: Reference/PubChem-compound 439165
xref: Reference/CAS 59-56-3
xref: Reference/BioCyc GLC-1-P
xref: Reference/ChEBI CHEBI 16077
xref: Reference/KEGG Compound C00103
xref: Reference/ChemSpider 388311
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001207

dTDP-4-dehydrorhamnose reductase
type: Protein
cellular location: Cytoplasm
entity reference: dTDP-4-dehydrorhamnose reductase

Reference/KEGG Compound C00092
type: UnificationXref
id: C00092
db: KEGG Compound

Reference/CAS 2147-59-3
type: UnificationXref
id: 2147-59-3
db: CAS

Protein/Generic518 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: [Acyl-carrier protein]
stoichiometric coefficient: 2.0

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

dTDP-β-L-rhamnose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: dTDP-β-L-rhamnose

Reference/CAS 2196-62-5
type: UnificationXref
id: 2196-62-5
db: CAS

ChemicalStructure/PW C044520
type: ChemicalStructure
structure format: SMILES

2.3.1.-
type: BiochemicalReaction
participant stoichiometry: Protein/Generic518 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/Generic203 Inner Membrane/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic580 Inner Membrane/Stoichiometry/1.0
right: [Acyl-carrier protein]
right: (3R)-(3-Hydroxyalkanoyloxy)alkanoate
right: Hydrogen Ion
spontaneous: false
EC number: 2.3.1.-
left: Water
left: (3R)-3-Hydroxyacyl-[acyl-carrier protein]
name: 2 (3R)-3-Hydroxyacyl-[acyl-carrier protein] + Water → (3R)-(3-Hydroxyalkanoyloxy)alkanoate + Hydrogen Ion + 2 [Acyl-carrier protein]
conversion direction: LEFT_TO_RIGHT

2.4.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000987 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002734 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic581 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic580 Inner Membrane/Stoichiometry/1.0
right: dTDP
right: Mono-rhamnolipid
right: Hydrogen Ion
spontaneous: false
EC number: 2.4.1.-
left: (3R)-(3-Hydroxyalkanoyloxy)alkanoate
left: dTDP-β-L-rhamnose
name: (3R)-(3-Hydroxyalkanoyloxy)alkanoate + dTDP-β-L-rhamnose → Hydrogen Ion + Mono-rhamnolipid + dTDP
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0001274
type: UnificationXref
id: HMDB0001274
db: HMDB

2.4.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000987 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002734 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic582 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/Generic581 Inner Membrane/Stoichiometry/1.0
right: dTDP
right: Di-rhamnolipid
right: Hydrogen Ion
spontaneous: false
EC number: 2.4.1.-
left: dTDP-β-L-rhamnose
left: Mono-rhamnolipid
name: Mono-rhamnolipid + dTDP-β-L-rhamnose → Di-rhamnolipid + Hydrogen Ion + dTDP
conversion direction: LEFT_TO_RIGHT

5.4.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001083 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001207 Cytoplasm/Stoichiometry/1.0
right: Glucose 1-phosphate
spontaneous: false
EC number: 5.4.2.2
left: Glucose 6-phosphate
name: Glucose 6-phosphate ↔ Glucose 1-phosphate
conversion direction: REVERSIBLE

Reference/CAS 491-97-4
type: UnificationXref
id: 491-97-4
db: CAS

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/TAXONOMY 4932
type: UnificationXref
id: 4932
db: TAXONOMY

ChemicalStructure/PW C000987
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-73-5
type: UnificationXref
id: 56-73-5
db: CAS

Phosphomannomutase/phosphoglucomutase
type: Protein
cellular location: Cytoplasm
entity reference: Phosphomannomutase/phosphoglucomutase

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Rhamnosyltransferase chain B
type: Protein
cellular location: Inner Membrane
entity reference: Rhamnosyltransferase chain B

Reference/TAXONOMY 287
type: UnificationXref
id: 287
db: TAXONOMY

Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Glucose 6-phosphate

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C042658 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-D-glucose
stoichiometric coefficient: 1.0

Di-rhamnolipid
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Di-rhamnolipid

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

(3R)-3-Hydroxyacyl-[acyl-carrier protein]
type: Protein
cellular location: Cell Membrane
entity reference: (3R)-3-Hydroxyacyl-[acyl-carrier protein]
name: SubPathwayOutput

Thymidine 5'-triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Thymidine 5'-triphosphate

Compound/PW C002734 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-β-L-rhamnose
stoichiometric coefficient: 1.0

Reaction187052
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042658 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024 Cytoplasm/Stoichiometry/1.0
right: dTDP-4-dehydro-6-deoxy-D-glucose
right: Water
spontaneous: false
left: dTDP-D-glucose
name: dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose
conversion direction: LEFT_TO_RIGHT

(3R)-(3-Hydroxyalkanoyloxy)alkanoate
type: SmallMoleculeReference

Mono-rhamnolipid
type: SmallMoleculeReference

Di-rhamnolipid
type: SmallMoleculeReference