Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Compound/PW C108992 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

Dihydroorotase, mitochondrial
type: Protein
cellular location: Mitochondrion
entity reference: Dihydroorotase, mitochondrial

ReactionCatalysis202510
type: Catalysis
controller: Aspartate carbamoyltransferase, chloroplastic
controlled: 2.1.3.2
control type: ACTIVATION

Reference/CAS 964-26-1
type: UnificationXref
id: 964-26-1
db: CAS

Compound/PW C001189 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Reference/ChemSpider 58580
type: UnificationXref
id: 58580
db: ChemSpider

dUDP
type: SmallMolecule
cellular location: Cytosol
entity reference: dUDP

Cytidine triphosphate
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Cytidine triphosphate

N-Carbamoyl-L-aspartate
type: SmallMolecule
cellular location: Chloroplast
entity reference: N-Carbamoyl-L-aspartate

Compound/PW C000191 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribose
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6133
type: UnificationXref
id: 6133
db: PubChem-compound

ReactionCatalysis202528
type: Catalysis
controller: Probable apyrase 4
controlled: Reaction212892
control type: ACTIVATION

ReactionCatalysis202529
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: 2.7.4.6
control type: ACTIVATION

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Reference/PubChem-compound 6132
type: UnificationXref
id: 6132
db: PubChem-compound

dCDP
type: SmallMolecule
cellular location: Nucleus
entity reference: dCDP

ReactionCatalysis202524
type: Catalysis
controller: Uridine 5'-monophosphate synthase
controlled: Reaction212889
control type: ACTIVATION

ReactionCatalysis202525
type: Catalysis
controller: Probable apyrase 4
controlled: 3.6.1.5
control type: ACTIVATION

Dihydrofolic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00415
xref: Reference/BioCyc DIHYDROFOLATE
xref: Reference/ChEBI CHEBI 15633
xref: Reference/ChemSpider 89228
xref: Reference/PubChem-compound 98792
xref: Reference/HMDB HMDB0001056
xref: Reference/CAS 4033-27-6
chemical formula: C19H21N7O6
molecular weight: 443.15533
structure: ChemicalStructure/PW C000831

ReactionCatalysis202526
type: Catalysis
controller: Probable UMP-CMP kinase 1
controlled: 2.7.4.14
control type: ACTIVATION

ReactionCatalysis202527
type: Catalysis
controller: Amino acid kinase family protein
controlled: 2.7.4.14
control type: ACTIVATION

ReactionCatalysis202521
type: Catalysis
controller: Dihydroorotase, mitochondrial
controlled: 3.5.2.3
control type: ACTIVATION

ReactionCatalysis202522
type: Catalysis
controller: Dihydroorotate dehydrogenase (quinone), mitochondrial
controlled: 1.3.5.2
control type: ACTIVATION

ReactionCatalysis202523
type: Catalysis
controller: Uridine 5'-monophosphate synthase
controlled: 2.4.2.10,4.1.1.23
control type: ACTIVATION

Reference/UniProt P49077
type: UnificationXref
id: P49077
db: UniProt

Compound/PW C000095 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17594
type: UnificationXref
id: CHEBI:17594
db: ChEBI

Reference/ChEBI CHEBI 17111
type: UnificationXref
id: CHEBI:17111
db: ChEBI

Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Adenosine diphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine diphosphate

Reference/UniProt Q9LVI9
type: UnificationXref
id: Q9LVI9
db: UniProt

Reference/CAS 63-38-7
type: UnificationXref
id: 63-38-7
db: CAS

Reference/ChEBI CHEBI 17568
type: UnificationXref
id: CHEBI:17568
db: ChEBI

Reference/KEGG Compound C00458
type: UnificationXref
id: C00458
db: KEGG Compound

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Reference/BioCyc HCO3
type: UnificationXref
id: HCO3
db: BioCyc

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Carbamoyl-phosphate synthase large chain, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q42601
organism: Arabidopsis thaliana

Probable apyrase 4
type: Protein
cellular location: Cell Membrane
entity reference: Probable apyrase 4

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Aspartate carbamoyltransferase, chloroplastic
type: ProteinReference
xref: Reference/UniProt P49077
organism: Arabidopsis thaliana

dTMP
type: SmallMolecule
cellular location: Cytoplasm
entity reference: dTMP

3.5.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C109002 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000040 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Ammonia
right: β-Alanine
right: Carbon dioxide
spontaneous: false
EC number: 3.5.1.6
left: Hydrogen Ion
left: 3-Ureidopropionate
left: Water
name: 3-Ureidopropionate + Hydrogen Ion + Water → Ammonia + Carbon dioxide + β-Alanine
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00214
type: UnificationXref
id: C00214
db: KEGG Compound

Compound/PW C000202 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine
stoichiometric coefficient: 1.0

2.4.2.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000194 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000204 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108758 Chloroplast/Stoichiometry/1.0
right: 5-Phospho-alpha-D-ribose 1-diphosphate
right: Uracil
spontaneous: false
EC number: 2.4.2.9
left: Uridine 5'-monophosphate
left: Pyrophosphate
name: Pyrophosphate + Uridine 5'-monophosphate ↔ 5-Phospho-alpha-D-ribose 1-diphosphate + Uracil
conversion direction: REVERSIBLE

Compound/PW C000414 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Reaction213002
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001191 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000204 Peroxisome/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000984 Peroxisome/Stoichiometry/1.0
right: Pseudouridine 5'-phosphate
right: Water
spontaneous: false
left: Uracil
left: D-Ribose 5-phosphate
name: D-Ribose 5-phosphate + Uracil ↔ Pseudouridine 5'-phosphate + Water
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChEBI CHEBI 17562
type: UnificationXref
id: CHEBI:17562
db: ChEBI

Reference/ChemSpider 1141
type: UnificationXref
id: 1141
db: ChemSpider

Beta-ureidopropionase
type: Protein
cellular location: Cytosol
entity reference: Beta-ureidopropionase

ChemicalStructure/PW C001087
type: ChemicalStructure
structure format: SMILES

Reference/CAS 7540-64-9
type: UnificationXref
id: 7540-64-9
db: CAS

Reference/PubChem-compound 439175
type: UnificationXref
id: 439175
db: PubChem-compound

Thioredoxin
type: Protein
cellular location: Cytosol
entity reference: Thioredoxin

Reference/GENE ONTOLOGY GO 0009507
type: UnificationXref
id: GO:0009507
db: GENE ONTOLOGY

ReactionCatalysis202509
type: Catalysis
controller: Carbamoyl-phosphate synthase large chain, chloroplastic
controlled: 6.3.5.5
control type: ACTIVATION

Dihydroorotate dehydrogenase (quinone), mitochondrial
type: ProteinReference
xref: Reference/UniProt P32746
organism: Arabidopsis thaliana

Compound/PW C108996 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTTP
stoichiometric coefficient: 1.0

Uridine 5'-monophosphate synthase
type: ProteinReference
xref: Reference/UniProt Q42586
organism: Arabidopsis thaliana

Reference/KEGG Compound C00460
type: UnificationXref
id: C00460
db: KEGG Compound

Probable UMP-CMP kinase 1
type: Protein
cellular location: Cytosol
entity reference: Probable UMP-CMP kinase 1

Dihydroorotase, mitochondrial
type: ProteinReference
xref: Reference/UniProt O04904
organism: Arabidopsis thaliana

Reference/PubChem-compound 439167
type: UnificationXref
id: 439167
db: PubChem-compound

Reference/UniProt Q9S750
type: UnificationXref
id: Q9S750
db: UniProt

Reference/HMDB HMDB0001096
type: UnificationXref
id: HMDB0001096
db: HMDB

Compound/PW C000192 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00239
type: UnificationXref
id: C00239
db: KEGG Compound

Pseudouridine 5'-phosphate
type: SmallMolecule
cellular location: Peroxisome
entity reference: Pseudouridine 5'-phosphate

Carbamoyl phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 278
xref: Reference/BioCyc CARBAMOYL-P
xref: Reference/ChemSpider 272
xref: Reference/HMDB HMDB0001096
xref: Reference/CAS 590-55-6
xref: Reference/KEGG Compound C00169
xref: Reference/ChEBI CHEBI 17672
chemical formula: CH4NO5P
molecular weight: 140.98271
structure: ChemicalStructure/PW C000862

Compound/PW C000064 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00472
type: UnificationXref
id: C00472
db: KEGG Compound

Compound/PW C000064 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Deoxyuridine 5'-triphosphate nucleotidohydrolase
type: Protein
cellular location: Cytosol
entity reference: Deoxyuridine 5'-triphosphate nucleotidohydrolase

Reference/PathWhiz PW123949
type: UnificationXref
id: PW123949
db: PathWhiz

Compound/PW C000937 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dCMP
stoichiometric coefficient: 1.0

Nucleoside diphosphate kinase 1
type: Protein
cellular location: Nucleus
entity reference: Nucleoside diphosphate kinase 1

Reference/KEGG Compound C00475
type: UnificationXref
id: C00475
db: KEGG Compound

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Dihydrothymine
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Dihydrothymine

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/UniProt P39207
type: UnificationXref
id: P39207
db: UniProt

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C001034 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

dTMP
type: SmallMolecule
cellular location: Cell Membrane
entity reference: dTMP

Mitochondrial Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005743

ChemicalStructure/PW C109002
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCNC(O)=N

Compound/PW C000927 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C000201 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

thymidine kinase 1a
type: Protein
cellular location: Cytoplasm
entity reference: thymidine kinase 1a

Compound/PW C000984 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pseudouridine 5'-phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis202531
type: Catalysis
controller: CTP synthase
controlled: 6.3.4.2
control type: ACTIVATION

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/KEGG Compound C00015
type: UnificationXref
id: C00015
db: KEGG Compound

Reference/KEGG Compound C01346
type: UnificationXref
id: C01346
db: KEGG Compound

Reference/KEGG Compound C00014
type: UnificationXref
id: C00014
db: KEGG Compound

Compound/PW C108936 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Carbamoyl-L-aspartate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

ReactionCatalysis202530
type: Catalysis
controller: Alkaline-phosphatase-like family protein
controlled: 3.6.1.9
control type: ACTIVATION

dTMP
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: dTMP

Compound/PW C000057 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Unknown
type: ProteinReference

Compound/PW C000190 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoribosyl pyrophosphate
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 58574
type: UnificationXref
id: 58574
db: ChemSpider

Compound/PW C000056 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrothymine
stoichiometric coefficient: 1.0

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Carbamoyl phosphate
type: SmallMolecule
entity reference: Carbamoyl phosphate
name: SubPathwayOutput

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Compound/PW C000057 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 3432-99-3
type: UnificationXref
id: 3432-99-3
db: CAS

Compound/PW C000057 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Ribonucleoside-diphosphate reductase small chain A
type: Protein
cellular location: Cytosol
entity reference: Ribonucleoside-diphosphate reductase small chain A

thymidine kinase 1a
type: ProteinReference
xref: Reference/UniProt Q9S750
organism: Arabidopsis thaliana

cytidine deaminase
type: ProteinReference
xref: Reference/UniProt O65896
organism: Arabidopsis thaliana

thymidylate kinase
type: ProteinReference
xref: Reference/UniProt Q0WW55
organism: Arabidopsis thaliana

TransportCatalysis2017
type: Catalysis
controller: Unknown
controlled: Transport10845
control type: ACTIVATION

TransportCatalysis2016
type: Catalysis
controller: Unknown
controlled: Transport10844
control type: ACTIVATION

TransportCatalysis2019
type: Catalysis
controller: Unknown
controlled: Transport10847
control type: ACTIVATION

TransportCatalysis2018
type: Catalysis
controller: Unknown
controlled: Transport10846
control type: ACTIVATION

TransportCatalysis2013
type: Catalysis
controller: Unknown
controlled: Transport10841
control type: ACTIVATION

Reference/PubChem-compound 769
type: UnificationXref
id: 769
db: PubChem-compound

TransportCatalysis2012
type: Catalysis
controller: Unknown
controlled: Transport10840
control type: ACTIVATION

TransportCatalysis2015
type: Catalysis
controller: Unknown
controlled: Transport10843
control type: ACTIVATION

TransportCatalysis2014
type: Catalysis
controller: Unknown
controlled: Transport10842
control type: ACTIVATION

ReactionCatalysis202597
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: Reaction212967
control type: ACTIVATION

ReactionCatalysis202598
type: Catalysis
controller: thymidylate kinase
controlled: Reaction212968
control type: ACTIVATION

ReactionCatalysis202599
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: Reaction212969
control type: ACTIVATION

Reference/UniProt Q9STG6
type: UnificationXref
id: Q9STG6
db: UniProt

Reference/CAS 504-07-4
type: UnificationXref
id: 504-07-4
db: CAS

ReactionCatalysis202593
type: Catalysis
controller: cytidine deaminase
controlled: 3.5.4.5
control type: ACTIVATION

ReactionCatalysis202594
type: Catalysis
controller: Unknown
controlled: 5.4.99.-
control type: ACTIVATION

Carbamoyl phosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Carbamoyl phosphate

ReactionCatalysis202595
type: Catalysis
controller: Unknown
controlled: Reaction212965
control type: ACTIVATION

Reference/ChemSpider 128553
type: UnificationXref
id: 128553
db: ChemSpider

ReactionCatalysis202590
type: Catalysis
controller: CMP/dCMP-type deaminase domain-containing protein
controlled: Reaction212958
control type: ACTIVATION

ReactionCatalysis202591
type: Catalysis
controller: thymidine kinase 1a
controlled: Reaction212961
control type: ACTIVATION

Compound/PW C108936 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Carbamoyl-L-aspartate
stoichiometric coefficient: 1.0

ReactionCatalysis202592
type: Catalysis
controller: 5′-nucleotidase
controlled: Reaction212962
control type: ACTIVATION

ChemicalStructure/PW C000179
type: ChemicalStructure
structure format: SMILES
structure data: CC1=CNC(=O)NC1=O

Compound/PW C108986 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C108986
type: ChemicalStructure
structure format: SMILES

TransportCatalysis2011
type: Catalysis
controller: Unknown
controlled: Transport10839
control type: ACTIVATION

Adenosine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Adenosine triphosphate

TransportCatalysis2010
type: Catalysis
controller: Unknown
controlled: Transport10838
control type: ACTIVATION

Reference/PubChem-compound 98792
type: UnificationXref
id: 98792
db: PubChem-compound

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Pyrimidine Metabolism
type: Pathway
pathway order: PathwayTransport/2461216
pathway order: PathwayEnzymeReaction/2461232
pathway order: PathwayTransport/2461217
pathway order: PathwayEnzymeReaction/2461197
pathway order: PathwayTransport/2461219
pathway order: PathwayEnzymeReaction/2461151
pathway order: PathwayEnzymeReaction/2461195
pathway order: PathwayTransport/2461213
pathway order: PathwayTransport/2461257
pathway order: PathwayEnzymeReaction/2461150
pathway order: PathwayEnzymeReaction/2461194
pathway order: PathwayTransport/2461259
pathway order: PathwayTransport/2461252
pathway order: PathwayEnzymeReaction/2461159
pathway order: PathwayEnzymeReaction/2461236
pathway order: PathwayEnzymeReaction/2460940
pathway order: PathwayTransport/2461173
pathway order: PathwayTransport/2461250
pathway order: PathwayEnzymeReaction/2460938
pathway order: PathwayEnzymeReaction/2460939
pathway order: PathwayEnzymeReaction/2460936
pathway order: PathwayEnzymeReaction/2460937
pathway order: PathwayEnzymeReaction/2461192
pathway order: PathwaySubPathway/112780
pathway order: PathwaySubPathway/112781
pathway order: PathwayTransport/2460923
pathway order: PathwaySubPathway/112782
pathway order: PathwayTransport/2460910
pathway order: PathwayEnzymeReaction/2461164
pathway order: PathwayEnzymeReaction/2461242
pathway order: PathwayEnzymeReaction/2461163
pathway order: PathwayEnzymeReaction/2461240
pathway order: PathwayTransport/2461246
pathway order: PathwayTransport/2461204
pathway order: PathwayTransport/2461248
pathway order: PathwayEnzymeReaction/2461208
pathway order: PathwayEnzymeReaction/2461205
pathway order: PathwayEnzymeReaction/2461249
pathway order: PathwayTransport/2461200
pathway order: PathwayEnzymeReaction/2461206
pathway order: PathwayTransport/2461160
pathway order: PathwayEnzymeReaction/2461247
pathway order: PathwayEnzymeReaction/2461168
pathway order: PathwayEnzymeReaction/2461201
pathway order: PathwayEnzymeReaction/2461202
pathway order: PathwayEnzymeReaction/2460907
pathway order: PathwayEnzymeReaction/2460908
pathway order: PathwayEnzymeReaction/2460945
pathway order: PathwayEnzymeReaction/2461210
pathway order: PathwayEnzymeReaction/2461254
pathway order: PathwayEnzymeReaction/2461211
pathway order: PathwayTransport/2461239
pathway order: PathwayEnzymeReaction/2461255
pathway order: PathwayEnzymeReaction/2461175
pathway order: PathwaySubPathway/112799
pathway order: PathwayTransport/2461234
pathway order: PathwayTransport/2461158
pathway order: PathwayTransport/2461235
pathway order: PathwayEnzymeReaction/2461251
pathway order: PathwayTransport/2461237
pathway order: PathwayTransport/2461153
pathway order: PathwayEnzymeReaction/2461218
pathway order: PathwayEnzymeReaction/2461258
pathway order: PathwayEnzymeReaction/2461215
pathway order: PathwayEnzymeReaction/2461179
pathway order: PathwayEnzymeReaction/2461256
pathway order: PathwayTransport/2460909
pathway order: PathwayEnzymeReaction/2460914
pathway order: PathwayEnzymeReaction/2460915
pathway order: PathwayEnzymeReaction/2460912
pathway order: PathwayEnzymeReaction/2460913
pathway order: PathwayEnzymeReaction/2461188
pathway order: PathwayEnzymeReaction/2461265
pathway order: PathwayTransport/2461228
pathway order: PathwayTransport/2461229
pathway order: PathwayEnzymeReaction/2461263
pathway order: PathwayEnzymeReaction/2461187
pathway order: PathwayEnzymeReaction/2461220
pathway order: PathwayEnzymeReaction/2461184

Water
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Water

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

Reference/KEGG Compound C00288
type: UnificationXref
id: C00288
db: KEGG Compound

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108991
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000187
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C108990
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc DIHYDROFOLATE
type: UnificationXref
id: DIHYDROFOLATE
db: BioCyc

Reference/ChemSpider 7062
type: UnificationXref
id: 7062
db: ChemSpider

Compound/PW C000192 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

ChemicalStructure/PW C108994
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](CN)C(O)=O

ChemicalStructure/PW C108993
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](CNC(N)=O)C(O)=O

ChemicalStructure/PW C108992
type: ChemicalStructure
structure format: SMILES

Uridine 5'-diphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17659
xref: Reference/PubChem-compound 6031
xref: Reference/CAS 58-98-0
xref: Reference/HMDB HMDB0000295
xref: Reference/KEGG Compound C00015
xref: Reference/ChemSpider 5809
xref: Reference/BioCyc UDP
chemical formula: C9H14N2O12P2
molecular weight: 404.0022
structure: ChemicalStructure/PW C000201

ChemicalStructure/PW C108996
type: ChemicalStructure
structure format: SMILES

Compound/PW C000061 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine
stoichiometric coefficient: 1.0

Reference/BioCyc UTP
type: UnificationXref
id: UTP
db: BioCyc

ChemicalStructure/PW C108758
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 5902
type: UnificationXref
id: 5902
db: ChemSpider

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/PubChem-compound 785
type: UnificationXref
id: 785
db: PubChem-compound

Reference/ChemSpider 5903
type: UnificationXref
id: 5903
db: ChemSpider

ReactionCatalysis202579
type: Catalysis
controller: Probable apyrase 4
controlled: Reaction212946
control type: ACTIVATION

L-Glutamine
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Glutamine
name: SubPathwayOutput

5-Phospho-alpha-D-ribose 1-diphosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: 5-Phospho-alpha-D-ribose 1-diphosphate

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Reference/KEGG Compound C00299
type: UnificationXref
id: C00299
db: KEGG Compound

Reference/HMDB HMDB0001245
type: UnificationXref
id: HMDB0001245
db: HMDB

2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/PubChem-compound 145729
type: UnificationXref
id: 145729
db: PubChem-compound

5,10-Methylene-THF
type: SmallMolecule
cellular location: Cytosol
entity reference: 5,10-Methylene-THF

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0001000
type: UnificationXref
id: HMDB0001000
db: HMDB

Reference/BioCyc DUDP
type: UnificationXref
id: DUDP
db: BioCyc

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/UniProt Q9SJ20
type: UnificationXref
id: Q9SJ20
db: UniProt

ReactionCatalysis202586
type: Catalysis
controller: Ribonucleoside-diphosphate reductase
controlled: 1.17.4.1
control type: ACTIVATION

ReactionCatalysis202587
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: Reaction212955
control type: ACTIVATION

ReactionCatalysis202588
type: Catalysis
controller: Probable UMP-CMP kinase 1
controlled: Reaction212956
control type: ACTIVATION

Reference/CAS 613-83-2
type: UnificationXref
id: 613-83-2
db: CAS

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

ReactionCatalysis202589
type: Catalysis
controller: 5′-nucleotidase
controlled: Reaction212957
control type: ACTIVATION

ReactionCatalysis202582
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: 2.7.4.6
control type: ACTIVATION

ReactionCatalysis202583
type: Catalysis
controller: Probable UMP-CMP kinase 1
controlled: Reaction212951
control type: ACTIVATION

Reference/CAS 4033-27-6
type: UnificationXref
id: 4033-27-6
db: CAS

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ReactionCatalysis202580
type: Catalysis
controller: Probable apyrase 4
controlled: Reaction212947
control type: ACTIVATION

Reference/CAS 58-96-8
type: UnificationXref
id: 58-96-8
db: CAS

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

dTTP
type: SmallMolecule
cellular location: Nucleus
entity reference: dTTP

3.6.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000927 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: Pyrophosphate
right: dUMP
spontaneous: false
EC number: 3.6.1.23
left: Deoxyuridine triphosphate
left: Water
name: Deoxyuridine triphosphate + Water → Hydrogen Ion + Pyrophosphate + dUMP
conversion direction: LEFT_TO_RIGHT

Reaction212973
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000187 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Thymidine
spontaneous: false
left: dTMP
left: Water
name: Water + dTMP → Phosphate + Thymidine
conversion direction: LEFT_TO_RIGHT

Compound/PW C000007 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine
stoichiometric coefficient: 1.0

Reaction212974
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000187 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
right: Thymidine
right: Adenosine triphosphate
spontaneous: false
left: dTMP
left: Adenosine diphosphate
name: Adenosine diphosphate + dTMP ← Adenosine triphosphate + Thymidine
conversion direction: RIGHT_TO_LEFT

Reaction212975
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000187 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000179 Cytosol/Stoichiometry/1.0
right: Thymine
spontaneous: false
left: Thymidine
name: Thymidine ↔ Thymine
conversion direction: REVERSIBLE

1.3.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000056 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000179 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: Dihydrothymine
right: NADP
spontaneous: false
EC number: 1.3.1.2
left: Hydrogen Ion
left: Thymine
left: NADPH
name: Hydrogen Ion + NADPH + Thymine ↔ Dihydrothymine + NADP
conversion direction: REVERSIBLE

3.5.2.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000056 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108993 Endoplasmic Reticulum/Stoichiometry/1.0
right: 3-Ureidoisobutyrate
spontaneous: false
EC number: 3.5.2.2
left: Dihydrothymine
left: Water
name: Dihydrothymine + Water ↔ 3-Ureidoisobutyrate
conversion direction: REVERSIBLE

3.5.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108994 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108993 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Ammonia
right: Carbon dioxide
right: 3-Aminoisobutyrate
spontaneous: false
EC number: 3.5.1.6
left: 3-Ureidoisobutyrate
left: Water
name: 3-Ureidoisobutyrate + Water → 3-Aminoisobutyrate + Ammonia + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reference/CAS 58-98-0
type: UnificationXref
id: 58-98-0
db: CAS

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/KEGG Compound C00075
type: UnificationXref
id: C00075
db: KEGG Compound

Reference/ChEBI CHEBI 18075
type: UnificationXref
id: CHEBI:18075
db: ChEBI

Reference/PubChem-compound 13712
type: UnificationXref
id: 13712
db: PubChem-compound

Reference/UniProt O04904
type: UnificationXref
id: O04904
db: UniProt

Quinone
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Quinone

Reference/PubChem-compound 13711
type: UnificationXref
id: 13711
db: PubChem-compound

Reaction212970
type: BiochemicalReaction
participant stoichiometry: Protein/Generic27 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000792 Cytosol/Stoichiometry/1.0
participant stoichiometry: Protein/Generic28 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Cytosol/Stoichiometry/1.0
right: Thioredoxin
right: Uridine 5'-diphosphate
spontaneous: false
left: dUDP
left: Thioredoxin disulfide
left: Water
name: Thioredoxin disulfide + Water + dUDP ← Thioredoxin + Uridine 5'-diphosphate
conversion direction: RIGHT_TO_LEFT

1.5.1.3,2.1.1.45
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000831 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001178 Cytosol/Stoichiometry/1.0
right: Dihydrofolic acid
right: dTMP
spontaneous: false
EC number: 1.5.1.3,2.1.1.45
left: 5,10-Methylene-THF
left: dUMP
name: 5,10-Methylene-THF + dUMP → Dihydrofolic acid + dTMP
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C01168
type: UnificationXref
id: C01168
db: KEGG Compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 951-77-9
type: UnificationXref
id: 951-77-9
db: CAS

Adenosine triphosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Adenosine triphosphate

Compound/PW C001189 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Reference/UniProt P50651
type: UnificationXref
id: P50651
db: UniProt

Cytidine monophosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Cytidine monophosphate

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reaction212983
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000987 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108996 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: dTDP
spontaneous: false
left: Water
left: dTTP
name: Water + dTTP → Phosphate + dTDP
conversion direction: LEFT_TO_RIGHT

Reaction212984
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Plant-Type Vacuole/Stoichiometry/1.0
right: Cytidine monophosphate
right: Pyrophosphate
spontaneous: false
left: Cytidine triphosphate
left: Water
name: Cytidine triphosphate + Water → Cytidine monophosphate + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 6175
type: UnificationXref
id: 6175
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reaction212986
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108992 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108996 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Plant-Type Vacuole/Stoichiometry/1.0
right: Pyrophosphate
right: dTMP
spontaneous: false
left: dTTP
left: Water
name: Water + dTTP → Pyrophosphate + dTMP
conversion direction: LEFT_TO_RIGHT

Reaction212988
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000061 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Cytidine
spontaneous: false
left: Cytidine monophosphate
left: Water
name: Cytidine monophosphate + Water → Cytidine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 13945
type: UnificationXref
id: 13945
db: PubChem-compound

Reference/BioCyc THYMINE
type: UnificationXref
id: THYMINE
db: BioCyc

Reaction212980
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000987 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: dTDP
right: Adenosine diphosphate
spontaneous: false
left: dTMP
left: Adenosine triphosphate
name: Adenosine triphosphate + dTMP ↔ Adenosine diphosphate + dTDP
conversion direction: REVERSIBLE

Reaction212981
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000987 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108996 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: dTTP
right: Adenosine diphosphate
spontaneous: false
left: dTDP
left: Adenosine triphosphate
name: Adenosine triphosphate + dTDP ↔ Adenosine diphosphate + dTTP
conversion direction: REVERSIBLE

Reaction212982
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000987 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: dTMP
spontaneous: false
left: dTDP
left: Water
name: Water + dTDP → Phosphate + dTMP
conversion direction: LEFT_TO_RIGHT

Phosphoribosyl pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphoribosyl pyrophosphate
name: SubPathwayOutput

Reference/HMDB HMDB0001271
type: UnificationXref
id: HMDB0001271
db: HMDB

Reference/HMDB HMDB0001274
type: UnificationXref
id: HMDB0001274
db: HMDB

Reaction212994
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000194 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000202 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: Uridine
right: Adenosine triphosphate
spontaneous: false
left: Hydrogen Ion
left: Uridine 5'-monophosphate
left: Adenosine diphosphate
name: Adenosine diphosphate + Hydrogen Ion + Uridine 5'-monophosphate ← Adenosine triphosphate + Uridine
conversion direction: RIGHT_TO_LEFT

Reference/ChemSpider 1103
type: UnificationXref
id: 1103
db: ChemSpider

3.5.4.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000202 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000061 Cytosol/Stoichiometry/1.0
right: Ammonia
right: Uridine
spontaneous: false
EC number: 3.5.4.5
left: Hydrogen Ion
left: Cytidine
left: Water
name: Cytidine + Hydrogen Ion + Water → Ammonia + Uridine
conversion direction: LEFT_TO_RIGHT

Reaction212996
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000194 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000202 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Uridine
spontaneous: false
left: Uridine 5'-monophosphate
left: Water
name: Uridine 5'-monophosphate + Water → Phosphate + Uridine
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

3.2.2.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000204 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000202 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000191 Cytosol/Stoichiometry/1.0
right: Uracil
right: D-Ribose
spontaneous: false
EC number: 3.2.2.3
left: Uridine
left: Water
name: Uridine + Water → D-Ribose + Uracil
conversion direction: LEFT_TO_RIGHT

Ribonucleoside-diphosphate reductase
type: Complex
cellular location: Cytosol
component: Ribonucleoside-diphosphate reductase large subunit
component: Ribonucleoside-diphosphate reductase small chain A

Reference/ChemSpider 84456
type: UnificationXref
id: 84456
db: ChemSpider

Reaction212998
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000053 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000204 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: Dihydrouracil
right: NADP
spontaneous: false
left: Hydrogen Ion
left: Uracil
left: NADPH
name: Hydrogen Ion + NADPH + Uracil ↔ Dihydrouracil + NADP
conversion direction: REVERSIBLE

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Uracil
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17568
xref: Reference/KEGG Compound C00106
xref: Reference/HMDB HMDB0000300
xref: Reference/CAS 66-22-8
xref: Reference/BioCyc URACIL
xref: Reference/PubChem-compound 1174
xref: Reference/ChemSpider 1141
chemical formula: C4H4N2O2
molecular weight: 112.027275
structure: ChemicalStructure/PW C000204

Reaction212999
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000053 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C109002 Endoplasmic Reticulum/Stoichiometry/1.0
right: 3-Ureidopropionate
right: Hydrogen Ion
spontaneous: false
left: Dihydrouracil
left: Water
name: Dihydrouracil + Water ↔ 3-Ureidopropionate + Hydrogen Ion
conversion direction: REVERSIBLE

Compound/PW C108993 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Ureidoisobutyrate
stoichiometric coefficient: 1.0

Uridine
type: SmallMoleculeReference
xref: Reference/CAS 58-96-8
xref: Reference/ChEBI CHEBI 16704
xref: Reference/PubChem-compound 6029
xref: Reference/ChemSpider 5807
xref: Reference/BioCyc URIDINE
xref: Reference/HMDB HMDB0000296
xref: Reference/KEGG Compound C00299
chemical formula: C9H12N2O6
molecular weight: 244.06953
structure: ChemicalStructure/PW C000202

Reference/KEGG Compound C00099
type: UnificationXref
id: C00099
db: KEGG Compound

Reference/ChemSpider 5940
type: UnificationXref
id: 5940
db: ChemSpider

2.7.1.48,2.4.2.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000061 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Chloroplast/Stoichiometry/1.0
right: Cytidine
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.1.48,2.4.2.9
left: Hydrogen Ion
left: Cytidine monophosphate
left: Adenosine diphosphate
name: Adenosine diphosphate + Cytidine monophosphate + Hydrogen Ion ← Adenosine triphosphate + Cytidine
conversion direction: RIGHT_TO_LEFT

Compound/PW C001420 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

ChemicalStructure/PW C000190
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

ChemicalStructure/PW C000194
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000192
type: ChemicalStructure
structure format: SMILES

Nucleus
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005634

Reference/BioCyc DEOXYCYTIDINE
type: UnificationXref
id: DEOXYCYTIDINE
db: BioCyc

ChemicalStructure/PW C000191
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1OC(O)[C@H](O)[C@@H]1O

TransportCatalysis2006
type: Catalysis
controller: Unknown
controlled: Transport10834
control type: ACTIVATION

TransportCatalysis2005
type: Catalysis
controller: Unknown
controlled: Transport10833
control type: ACTIVATION

TransportCatalysis2008
type: Catalysis
controller: Unknown
controlled: Transport10836
control type: ACTIVATION

TransportCatalysis2007
type: Catalysis
controller: Unknown
controlled: Transport10835
control type: ACTIVATION

TransportCatalysis2002
type: Catalysis
controller: Unknown
controlled: Transport10830
control type: ACTIVATION

Alkaline-phosphatase-like family protein
type: Protein
cellular location: Plant-Type Vacuole
entity reference: Alkaline-phosphatase-like family protein

TransportCatalysis2001
type: Catalysis
controller: Unknown
controlled: Transport10829
control type: ACTIVATION

Reference/BioCyc UMP
type: UnificationXref
id: UMP
db: BioCyc

TransportCatalysis2004
type: Catalysis
controller: Unknown
controlled: Transport10832
control type: ACTIVATION

TransportCatalysis2003
type: Catalysis
controller: Unknown
controlled: Transport10831
control type: ACTIVATION

Reference/ChemSpider 629
type: UnificationXref
id: 629
db: ChemSpider

dTMP
type: SmallMolecule
cellular location: Cytosol
entity reference: dTMP

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

TransportCatalysis2009
type: Catalysis
controller: Unknown
controlled: Transport10837
control type: ACTIVATION

Adenosine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Adenosine triphosphate

Reference/GENE ONTOLOGY GO 0000325
type: UnificationXref
id: GO:0000325
db: GENE ONTOLOGY

Compound/PW C001087 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dUMP
stoichiometric coefficient: 1.0

Reference/UniProt Q9M336
type: UnificationXref
id: Q9M336
db: UniProt

Compound/PW C000987 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP
stoichiometric coefficient: 1.0

Hydrogen carbonate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000595
xref: Reference/ChEBI CHEBI 17544
xref: Reference/PubChem-compound 769
xref: Reference/BioCyc HCO3
xref: Reference/ChemSpider 749
xref: Reference/CAS 71-52-3
xref: Reference/KEGG Compound C00288
chemical formula: CH2O3
molecular weight: 62.000393
structure: ChemicalStructure/PW C000463

TransportCatalysis2000
type: Catalysis
controller: Unknown
controlled: Transport10828
control type: ACTIVATION

Reference/HMDB HMDB0001056
type: UnificationXref
id: HMDB0001056
db: HMDB

CMP/dCMP-type deaminase domain-containing protein
type: Protein
cellular location: Cytosol
entity reference: CMP/dCMP-type deaminase domain-containing protein

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/CAS 1032-65-1
type: UnificationXref
id: 1032-65-1
db: CAS

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Transport10846
type: Transport
participant stoichiometry: Compound/PW C109002 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C109002 Endoplasmic Reticulum/Stoichiometry/1.0
right: 3-Ureidopropionate
spontaneous: false
left: 3-Ureidopropionate
name: 3-Ureidopropionate (→) Transport: Arabidopsis thaliana, Cell, Endoplasmic Reticulum to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

3-Ureidoisobutyrate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: 3-Ureidoisobutyrate

Transport10847
type: Transport
participant stoichiometry: Compound/PW C000204 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000204 Peroxisome/Stoichiometry/1.0
right: Uracil
spontaneous: false
left: Uracil
name: Uracil (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Peroxisome
conversion direction: LEFT_TO_RIGHT

Reference/TAXONOMY 3702
type: UnificationXref
id: 3702
db: TAXONOMY

Compound/PW C000170 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Transport10842
type: Transport
participant stoichiometry: Compound/PW C000202 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000202 Cytosol/Stoichiometry/1.0
right: Uridine
spontaneous: false
left: Uridine
name: Uridine (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1135
type: UnificationXref
id: 1135
db: PubChem-compound

Transport10843
type: Transport
participant stoichiometry: Compound/PW C000204 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000204 Cytosol/Stoichiometry/1.0
right: Uracil
spontaneous: false
left: Uracil
name: Uracil (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Chloroplast
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000204
type: ChemicalStructure
structure format: SMILES
structure data: O=C1NC=CC(=O)N1

Transport10844
type: Transport
participant stoichiometry: Compound/PW C000053 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000053 Cytosol/Stoichiometry/1.0
right: Dihydrouracil
spontaneous: false
left: Dihydrouracil
name: Dihydrouracil (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10845
type: Transport
participant stoichiometry: Compound/PW C000053 Endoplasmic Reticulum/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000053 Cytosol/Stoichiometry/1.0
right: Dihydrouracil
spontaneous: false
left: Dihydrouracil
name: Dihydrouracil (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Endoplasmic Reticulum
conversion direction: LEFT_TO_RIGHT

Transport10840
type: Transport
participant stoichiometry: Compound/PW C000064 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Cytosol/Stoichiometry/1.0
right: Cytidine monophosphate
spontaneous: false
left: Cytidine monophosphate
name: Cytidine monophosphate (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Chloroplast
conversion direction: LEFT_TO_RIGHT

Transport10841
type: Transport
participant stoichiometry: Compound/PW C000194 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000194 Chloroplast/Stoichiometry/1.0
right: Uridine 5'-monophosphate
spontaneous: false
left: Uridine 5'-monophosphate
name: Uridine 5'-monophosphate (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Chloroplast
conversion direction: LEFT_TO_RIGHT

Compound/PW C000008 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxycytidine
stoichiometric coefficient: 1.0

Ammonia
type: SmallMoleculeReference
xref: Reference/BioCyc AMMONIA
xref: Reference/CAS 7664-41-7
xref: Reference/HMDB HMDB0000051
xref: Reference/PubChem-compound 222
xref: Reference/KEGG Compound C00014
xref: Reference/ChEBI CHEBI 16134
xref: Reference/ChemSpider 217
chemical formula: H3N
molecular weight: 17.026548
structure: ChemicalStructure/PW C000035

Uracil
type: SmallMolecule
cellular location: Chloroplast
entity reference: Uracil

Compound/PW C000927 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine triphosphate
stoichiometric coefficient: 1.0

Transport10839
type: Transport
participant stoichiometry: Compound/PW C000061 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000061 Cytosol/Stoichiometry/1.0
right: Cytidine
spontaneous: false
left: Cytidine
name: Cytidine (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10835
type: Transport
participant stoichiometry: Compound/PW C000057 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Cytosol/Stoichiometry/1.0
right: Cytidine triphosphate
spontaneous: false
left: Cytidine triphosphate
name: Cytidine triphosphate (←) Transport: Arabidopsis thaliana, Cell, Plant-Type Vacuole to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10836
type: Transport
participant stoichiometry: Compound/PW C000064 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Cytosol/Stoichiometry/1.0
right: Cytidine monophosphate
spontaneous: false
left: Cytidine monophosphate
name: Cytidine monophosphate (←) Transport: Arabidopsis thaliana, Cell, Plant-Type Vacuole to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10837
type: Transport
participant stoichiometry: Compound/PW C108992 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Cytosol/Stoichiometry/1.0
right: dTMP
spontaneous: false
left: dTMP
name: dTMP (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Plant-Type Vacuole
conversion direction: LEFT_TO_RIGHT

Transport10838
type: Transport
participant stoichiometry: Compound/PW C108996 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108996 Plant-Type Vacuole/Stoichiometry/1.0
right: dTTP
spontaneous: false
left: dTTP
name: dTTP (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Plant-Type Vacuole
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Transport10831
type: Transport
participant stoichiometry: Compound/PW C108992 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108992 Nucleus/Stoichiometry/1.0
right: dTMP
spontaneous: false
left: dTMP
name: dTMP (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Nucleus
conversion direction: LEFT_TO_RIGHT

Transport10832
type: Transport
participant stoichiometry: Compound/PW C000927 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000927 Nucleus/Stoichiometry/1.0
right: Deoxyuridine triphosphate
spontaneous: false
left: Deoxyuridine triphosphate
name: Deoxyuridine triphosphate (→) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10833
type: Transport
participant stoichiometry: Compound/PW C000987 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000987 Cytosol/Stoichiometry/1.0
right: dTDP
spontaneous: false
left: dTDP
name: dTDP (→) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10834
type: Transport
participant stoichiometry: Compound/PW C108996 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108996 Cytosol/Stoichiometry/1.0
right: dTTP
spontaneous: false
left: dTTP
name: dTTP (→) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Transport10830
type: Transport
participant stoichiometry: Compound/PW C108993 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108993 Endoplasmic Reticulum/Stoichiometry/1.0
right: 3-Ureidoisobutyrate
spontaneous: false
left: 3-Ureidoisobutyrate
name: 3-Ureidoisobutyrate (→) Transport: Arabidopsis thaliana, Cell, Endoplasmic Reticulum to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Phosphate

Reference/HMDB HMDB0000300
type: UnificationXref
id: HMDB0000300
db: HMDB

Unknown
type: Protein
entity reference: Unknown

ChemicalStructure/PW C000463
type: ChemicalStructure
structure format: SMILES
structure data: OC(O)=O

Uridine nucleosidase 1
type: Protein
cellular location: Cytosol
entity reference: Uridine nucleosidase 1

β-Alanine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000056
xref: Reference/ChemSpider 234
xref: Reference/PubChem-compound 239
xref: Reference/ChEBI CHEBI 16958
xref: Reference/KEGG Compound C00099
xref: Reference/CAS 107-95-9
xref: Reference/BioCyc B-ALANINE
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C000040

Transport10828
type: Transport
participant stoichiometry: Compound/PW C000056 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000056 Chloroplast/Stoichiometry/1.0
right: Dihydrothymine
spontaneous: false
left: Dihydrothymine
name: Dihydrothymine (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10829
type: Transport
participant stoichiometry: Compound/PW C000056 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000056 Endoplasmic Reticulum/Stoichiometry/1.0
right: Dihydrothymine
spontaneous: false
left: Dihydrothymine
name: Dihydrothymine (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Endoplasmic Reticulum
conversion direction: LEFT_TO_RIGHT

Deoxycytidine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15698
xref: Reference/HMDB HMDB0000014
xref: Reference/CAS 951-77-9
xref: Reference/KEGG Compound C00881
xref: Reference/PubChem-compound 13711
xref: Reference/ChemSpider 13117
xref: Reference/BioCyc DEOXYCYTIDINE
chemical formula: C9H13N3O4
molecular weight: 227.0906
structure: ChemicalStructure/PW C000008

Deoxyuridine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00526
xref: Reference/HMDB HMDB0000012
xref: Reference/BioCyc DEOXYURIDINE
xref: Reference/PubChem-compound 13712
xref: Reference/ChemSpider 13118
xref: Reference/ChEBI CHEBI 16450
xref: Reference/CAS 951-78-0
chemical formula: C9H12N2O5
molecular weight: 228.07462
structure: ChemicalStructure/PW C000007

Transport10825
type: Transport
participant stoichiometry: Compound/PW C001087 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
right: dUMP
spontaneous: false
left: dUMP
name: dUMP (←) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/CAS 696-04-8
type: UnificationXref
id: 696-04-8
db: CAS

Transport10826
type: Transport
participant stoichiometry: Compound/PW C000792 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000792 Nucleus/Stoichiometry/1.0
right: dUDP
spontaneous: false
left: dUDP
name: dUDP (→) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10827
type: Transport
participant stoichiometry: Compound/PW C000179 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000179 Chloroplast/Stoichiometry/1.0
right: Thymine
spontaneous: false
left: Thymine
name: Thymine (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Chloroplast
conversion direction: LEFT_TO_RIGHT

Compound/PW C000192 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Transport10820
type: Transport
participant stoichiometry: Compound/PW C000064 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Nucleus/Stoichiometry/1.0
right: Cytidine monophosphate
spontaneous: false
left: Cytidine monophosphate
name: Cytidine monophosphate (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Nucleus
conversion direction: LEFT_TO_RIGHT

Transport10821
type: Transport
participant stoichiometry: Compound/PW C000962 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000962 Nucleus/Stoichiometry/1.0
right: dCDP
spontaneous: false
left: dCDP
name: dCDP (←) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10823
type: Transport
participant stoichiometry: Compound/PW C000937 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000937 Nucleus/Stoichiometry/1.0
right: dCMP
spontaneous: false
left: dCMP
name: dCMP (→) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Uridine 5'-monophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine 5'-monophosphate

Compound/PW C001632 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydroquinone
stoichiometric coefficient: 1.0

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/ChemSpider 272
type: UnificationXref
id: 272
db: ChemSpider

Reference/CAS 4208-67-7
type: UnificationXref
id: 4208-67-7
db: CAS

Deoxyuridine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Deoxyuridine triphosphate

2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
type: SmallMoleculeReference
chemical formula: C10H16N3O8P
molecular weight: 337.0675
structure: ChemicalStructure/PW C108986

Reference/BioCyc DUMP
type: UnificationXref
id: DUMP
db: BioCyc

Compound/PW C108993 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Ureidoisobutyrate
stoichiometric coefficient: 1.0

Transport10817
type: Transport
participant stoichiometry: Compound/PW C000194 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000194 Plant-Type Vacuole/Stoichiometry/1.0
right: Uridine 5'-monophosphate
spontaneous: false
left: Uridine 5'-monophosphate
name: Uridine 5'-monophosphate (→) Transport: Arabidopsis thaliana, Cell, Plant-Type Vacuole to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport10818
type: Transport
participant stoichiometry: Compound/PW C000057 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Cytosol/Stoichiometry/1.0
right: Cytidine triphosphate
spontaneous: false
left: Cytidine triphosphate
name: Cytidine triphosphate (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Nucleus
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Phosphate

Transport10819
type: Transport
participant stoichiometry: Compound/PW C001189 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Cytosol/Stoichiometry/1.0
right: CDP
spontaneous: false
left: CDP
name: CDP (↔) Transport: Arabidopsis thaliana, Cell, Nucleus to Arabidopsis thaliana, Cell, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15713
type: UnificationXref
id: CHEBI:15713
db: ChEBI

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Transport10816
type: Transport
participant stoichiometry: Compound/PW C000192 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000192 Plant-Type Vacuole/Stoichiometry/1.0
right: Uridine triphosphate
spontaneous: false
left: Uridine triphosphate
name: Uridine triphosphate (→) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Plant-Type Vacuole
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/HMDB HMDB0001409
type: UnificationXref
id: HMDB0001409
db: HMDB

2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate

Reference/BioCyc DI-H-URACIL
type: UnificationXref
id: DI-H-URACIL
db: BioCyc

Reference/PubChem-compound 4650
type: UnificationXref
id: 4650
db: PubChem-compound

Cytidine monophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Cytidine monophosphate

Compound/PW C001860 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Quinone
stoichiometric coefficient: 1.0

2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
type: SmallMoleculeReference
chemical formula: C10H17N3O11P2
molecular weight: 417.03384
structure: ChemicalStructure/PW C108990

2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
type: SmallMoleculeReference
chemical formula: C10H18N3O14P3
molecular weight: 497.00015
structure: ChemicalStructure/PW C108991

ChemicalStructure/PW C000202
type: ChemicalStructure
structure format: SMILES

Uracil
type: SmallMolecule
cellular location: Peroxisome
entity reference: Uracil

ChemicalStructure/PW C000201
type: ChemicalStructure
structure format: SMILES

dTMP
type: SmallMoleculeReference
chemical formula: C10H15N2O8P
molecular weight: 322.0566
structure: ChemicalStructure/PW C108992

Dihydrouracil
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Dihydrouracil

3-Ureidoisobutyrate
type: SmallMoleculeReference
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C108993

3-Aminoisobutyrate
type: SmallMoleculeReference
chemical formula: C4H9NO2
molecular weight: 103.06333
structure: ChemicalStructure/PW C108994

Hydrogen Ion
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Hydrogen Ion

dTTP
type: SmallMoleculeReference
chemical formula: C10H17N2O14P3
molecular weight: 481.98926
structure: ChemicalStructure/PW C108996

Reference/KEGG Compound C00906
type: UnificationXref
id: C00906
db: KEGG Compound

3-Ureidopropionate
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Ureidopropionate

ChemicalStructure/PW C108936
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](CC(O)=O)(NC(O)=N)C(O)=O

3-Aminoisobutyrate
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Aminoisobutyrate

5-Phospho-alpha-D-ribose 1-diphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 3419
xref: Reference/ChEBI CHEBI 17111
chemical formula: C5H13O14P3
molecular weight: 389.9518
structure: ChemicalStructure/PW C108758

Reference/UniProt Q0WW55
type: UnificationXref
id: Q0WW55
db: UniProt

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

ChemicalStructure/PW C000008
type: ChemicalStructure
structure format: SMILES

Compound/PW C000053 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrouracil
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMolecule
cellular location: Cytosol
entity reference: Carbon dioxide

ChemicalStructure/PW C000007
type: ChemicalStructure
structure format: SMILES

Compound/PW C000179 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymine
stoichiometric coefficient: 1.0

Dihydrothymine
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydrothymine

Reference/ChemSpider 217
type: UnificationXref
id: 217
db: ChemSpider

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/UniProt Q8VY84
type: UnificationXref
id: Q8VY84
db: UniProt

Reference/ChEBI CHEBI 28846
type: UnificationXref
id: CHEBI:28846
db: ChEBI

ChemicalStructure/PW C108944
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C1=CC(O)=NC(O)=N1

ChemicalStructure/PW C108943
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@]1(CC(O)=NC(O)=N1)C(O)=O

Reference/BioCyc CYTIDINE
type: UnificationXref
id: CYTIDINE
db: BioCyc

dUMP
type: SmallMolecule
cellular location: Cytosol
entity reference: dUMP

ChemicalStructure/PW C108946
type: ChemicalStructure
structure format: SMILES

Compound/PW C000962 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dCDP
stoichiometric coefficient: 1.0

Compound/PW C000194 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-monophosphate
stoichiometric coefficient: 1.0

Compound/PW C108944 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Orotate
stoichiometric coefficient: 1.0

Aspartate carbamoyltransferase, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Aspartate carbamoyltransferase, chloroplastic

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

5,10-Methylene-THF
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001533
xref: Reference/CAS 3432-99-3
xref: Reference/PubChem-compound 439175
xref: Reference/ChEBI CHEBI 15636
xref: Reference/KEGG Compound C00143
xref: Reference/BioCyc METHYLENE-THF
xref: Reference/ChemSpider 388320
chemical formula: C20H23N7O6
molecular weight: 457.171
structure: ChemicalStructure/PW C001178

Reference/SMPDB SMP0122634
type: UnificationXref
id: SMP0122634
db: SMPDB

Dihydrouracil
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydrouracil

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/HMDB HMDB0000595
type: UnificationXref
id: HMDB0000595
db: HMDB

Reference/HMDB HMDB0001202
type: UnificationXref
id: HMDB0001202
db: HMDB

Reference/ChemSpider 234
type: UnificationXref
id: 234
db: ChemSpider

Plant-Type Vacuole
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0000325

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005743
type: UnificationXref
id: GO:0005743
db: GENE ONTOLOGY

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

Dihydrothymine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000079
xref: Reference/ChEBI CHEBI 27468
xref: Reference/BioCyc DIHYDRO-THYMINE
xref: Reference/ChemSpider 84456
xref: Reference/CAS 696-04-8
xref: Reference/PubChem-compound 93556
xref: Reference/KEGG Compound C00906
chemical formula: C5H8N2O2
molecular weight: 128.05858
structure: ChemicalStructure/PW C000056

Dihydrouracil
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00429
xref: Reference/ChEBI CHEBI 15901
xref: Reference/ChemSpider 629
xref: Reference/PubChem-compound 649
xref: Reference/CAS 504-07-4
xref: Reference/BioCyc DI-H-URACIL
xref: Reference/HMDB HMDB0000076
chemical formula: C4H6N2O2
molecular weight: 114.04293
structure: ChemicalStructure/PW C000053

Reference/UniProt Q42601
type: UnificationXref
id: Q42601
db: UniProt

Uridine triphosphate
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Uridine triphosphate

Reference/KEGG Compound C00705
type: UnificationXref
id: C00705
db: KEGG Compound

D-Ribose 5-phosphate
type: SmallMolecule
cellular location: Peroxisome
entity reference: D-Ribose 5-phosphate

Compound/PW C108996 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTTP
stoichiometric coefficient: 1.0

Compound/PW C000064 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

dCTP
type: SmallMolecule
cellular location: Nucleus
entity reference: dCTP

Cytidine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000089
xref: Reference/PubChem-compound 6175
xref: Reference/BioCyc CYTIDINE
xref: Reference/ChemSpider 5940
xref: Reference/CAS 65-46-3
xref: Reference/KEGG Compound C00475
xref: Reference/ChEBI CHEBI 17562
chemical formula: C9H13N3O5
molecular weight: 243.08553
structure: ChemicalStructure/PW C000061

Reference/GENE ONTOLOGY GO 0005739
type: UnificationXref
id: GO:0005739
db: GENE ONTOLOGY

Water
type: SmallMolecule
cellular location: Chloroplast
entity reference: Water

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C108992 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

cytidine deaminase
type: Protein
cellular location: Cytosol
entity reference: cytidine deaminase

Compound/PW C000146 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Compound/PW C000143 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17748
type: UnificationXref
id: CHEBI:17748
db: ChEBI

Reference/UniProt Q9FMP3
type: UnificationXref
id: Q9FMP3
db: UniProt

TransportCatalysis1966
type: Catalysis
controller: Unknown
controlled: Transport10790
control type: ACTIVATION

Cytidine monophosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Cytidine monophosphate

TransportCatalysis1965
type: Catalysis
controller: Unknown
controlled: Transport10789
control type: ACTIVATION

TransportCatalysis1968
type: Catalysis
controller: Unknown
controlled: Transport10792
control type: ACTIVATION

Reference/BioCyc UDP
type: UnificationXref
id: UDP
db: BioCyc

Reference/ChEBI CHEBI 52742
type: UnificationXref
id: CHEBI:52742
db: ChEBI

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/BioCyc DIHYDRO-THYMINE
type: UnificationXref
id: DIHYDRO-THYMINE
db: BioCyc

TransportCatalysis1971
type: Catalysis
controller: Unknown
controlled: Transport10795
control type: ACTIVATION

Reference/PubChem-compound 93556
type: UnificationXref
id: 93556
db: PubChem-compound

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/BioCyc B-ALANINE
type: UnificationXref
id: B-ALANINE
db: BioCyc

Reference/PubChem-compound 65063
type: UnificationXref
id: 65063
db: PubChem-compound

Deoxyuridine
type: SmallMolecule
cellular location: Cytosol
entity reference: Deoxyuridine

Pyrophosphate
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Pyrophosphate

Compound/PW C000500 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Compound/PW C001420 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 65070
type: UnificationXref
id: 65070
db: PubChem-compound

Compound/PW C000962 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dCDP
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000862
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)OP(O)(O)=O

Compound/PW C000831 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrofolic acid
stoichiometric coefficient: 1.0

Water
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: Water

Compound/PW C108994 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Aminoisobutyrate
stoichiometric coefficient: 1.0

Uridine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine triphosphate

Uridine
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine

CDP
type: SmallMolecule
cellular location: Cytosol
entity reference: CDP

Compound/PW C109002 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Ureidopropionate
stoichiometric coefficient: 1.0

CDP
type: SmallMoleculeReference
xref: Reference/ChemSpider 5902
xref: Reference/PubChem-compound 6132
xref: Reference/HMDB HMDB0001546
xref: Reference/ChEBI CHEBI 17239
xref: Reference/BioCyc CDP
xref: Reference/CAS 63-38-7
xref: Reference/KEGG Compound C00112
chemical formula: C9H15N3O11P2
molecular weight: 403.0182
structure: ChemicalStructure/PW C001189

Reference/GENE ONTOLOGY GO 0005783
type: UnificationXref
id: GO:0005783
db: GENE ONTOLOGY

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

TransportCatalysis1995
type: Catalysis
controller: Unknown
controlled: Transport10821
control type: ACTIVATION

TransportCatalysis1994
type: Catalysis
controller: Unknown
controlled: Transport10820
control type: ACTIVATION

TransportCatalysis1997
type: Catalysis
controller: Unknown
controlled: Transport10825
control type: ACTIVATION

TransportCatalysis1996
type: Catalysis
controller: Unknown
controlled: Transport10823
control type: ACTIVATION

TransportCatalysis1991
type: Catalysis
controller: Unknown
controlled: Transport10817
control type: ACTIVATION

TransportCatalysis1990
type: Catalysis
controller: Unknown
controlled: Transport10816
control type: ACTIVATION

TransportCatalysis1993
type: Catalysis
controller: Unknown
controlled: Transport10819
control type: ACTIVATION

TransportCatalysis1992
type: Catalysis
controller: Unknown
controlled: Transport10818
control type: ACTIVATION

ChemicalStructure/PW C000831
type: ChemicalStructure
structure format: SMILES

TransportCatalysis1999
type: Catalysis
controller: Unknown
controlled: Transport10827
control type: ACTIVATION

TransportCatalysis1998
type: Catalysis
controller: Unknown
controlled: Transport10826
control type: ACTIVATION

Reference/PubChem-compound 65091
type: UnificationXref
id: 65091
db: PubChem-compound

Reference/BioCyc DUTP
type: UnificationXref
id: DUTP
db: BioCyc

β-Alanine
type: SmallMolecule
cellular location: Cytosol
entity reference: β-Alanine
name: SubPathwayInput

Reference/CAS 123-31-9
type: UnificationXref
id: 123-31-9
db: CAS

CTP synthase
type: Protein
cellular location: Cytosol
entity reference: CTP synthase

5′-nucleotidase
type: Protein
cellular location: Cytosol
entity reference: 5′-nucleotidase

Reference/GENE ONTOLOGY GO 0005777
type: UnificationXref
id: GO:0005777
db: GENE ONTOLOGY

D-Ribose 5-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00117
xref: Reference/ChEBI CHEBI 52742
xref: Reference/ChemSpider 388313
xref: Reference/HMDB HMDB0001548
xref: Reference/BioCyc RIBOSE-5P
xref: Reference/PubChem-compound 439167
xref: Reference/CAS 4300-28-1
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C001191

Reference/ChEBI CHEBI 28850
type: UnificationXref
id: CHEBI:28850
db: ChEBI

Reference/ChEBI CHEBI 17544
type: UnificationXref
id: CHEBI:17544
db: ChEBI

Protein/Generic27 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thioredoxin disulfide
stoichiometric coefficient: 1.0

Uridine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Uridine triphosphate

CDP
type: SmallMolecule
cellular location: Cell Membrane
entity reference: CDP

Reference/PubChem-compound 5779
type: UnificationXref
id: 5779
db: PubChem-compound

Compound/PW C001034 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1174
type: UnificationXref
id: 1174
db: PubChem-compound

Reference/ChEBI CHEBI 16450
type: UnificationXref
id: CHEBI:16450
db: ChEBI

Deoxyuridine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Deoxyuridine triphosphate

Reference/ChEBI CHEBI 16695
type: UnificationXref
id: CHEBI:16695
db: ChEBI

Thymidine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Thymidine

Compound/PW C108996 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTTP
stoichiometric coefficient: 1.0

5′-nucleotidase
type: ProteinReference
xref: Reference/UniProt Z0Z000
organism: Arabidopsis thaliana

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Cell Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005886

Reference/KEGG Compound C00526
type: UnificationXref
id: C00526
db: KEGG Compound

Chloroplast
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0009507

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Compound/PW C108991 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Compound/PW C000040 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-Alanine
stoichiometric coefficient: 1.0

Uridine 5'-monophosphate synthase
type: Protein
cellular location: Cytosol
entity reference: Uridine 5'-monophosphate synthase

dTDP
type: SmallMolecule
cellular location: Nucleus
entity reference: dTDP

Reference/ChemSpider 89228
type: UnificationXref
id: 89228
db: ChemSpider

Compound/PW C001420 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Adenosine diphosphate

Reference/BioCyc PRPP
type: UnificationXref
id: PRPP
db: BioCyc

Reference/KEGG Compound C00530
type: UnificationXref
id: C00530
db: KEGG Compound

Reference/HMDB HMDB0000998
type: UnificationXref
id: HMDB0000998
db: HMDB

Reference/UniProt Z0Z000
type: UnificationXref
id: Z0Z000
db: UniProt

Compound/PW C001420 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C000862 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbamoyl phosphate
stoichiometric coefficient: 1.0

Compound/PW C000123 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5789
type: UnificationXref
id: 5789
db: PubChem-compound

Reference/CAS 106-51-4
type: UnificationXref
id: 106-51-4
db: CAS

dUMP
type: SmallMolecule
cellular location: Nucleus
entity reference: dUMP

Reference/BioCyc DEOXYURIDINE
type: UnificationXref
id: DEOXYURIDINE
db: BioCyc

Compound/PW C000790 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dCTP
stoichiometric coefficient: 1.0

Dihydroorotate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Dihydroorotate

3-Ureidopropionate
type: SmallMoleculeReference
chemical formula: C4H8N2O3
molecular weight: 132.0535
structure: ChemicalStructure/PW C109002

Compound/PW C000053 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrouracil
stoichiometric coefficient: 1.0

Dihydrothymine
type: SmallMolecule
cellular location: Chloroplast
entity reference: Dihydrothymine

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C040034 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

ReactionCatalysis202631
type: Catalysis
controller: Uracil phosphoribosyltransferase, chloroplastic
controlled: 2.4.2.9
control type: ACTIVATION

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

ReactionCatalysis202630
type: Catalysis
controller: Beta-ureidopropionase
controlled: 3.5.1.6
control type: ACTIVATION

Reference/PubChem-compound 6029
type: UnificationXref
id: 6029
db: PubChem-compound

Dihydrouracil
type: SmallMolecule
cellular location: Chloroplast
entity reference: Dihydrouracil

Cytidine triphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Cytidine triphosphate

ReactionCatalysis202632
type: Catalysis
controller: Indigoidine synthase A family protein
controlled: Reaction213002
control type: ACTIVATION

Reference/UniProt P32746
type: UnificationXref
id: P32746
db: UniProt

Reference/ChEBI CHEBI 16134
type: UnificationXref
id: CHEBI:16134
db: ChEBI

Compound/PW C000194 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-monophosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Pyrophosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Pyrophosphate

Reference/HMDB HMDB0003364
type: UnificationXref
id: HMDB0003364
db: HMDB

Thymine
type: SmallMolecule
cellular location: Chloroplast
entity reference: Thymine

Reference/ChEBI CHEBI 17239
type: UnificationXref
id: CHEBI:17239
db: ChEBI

Reference/HMDB HMDB0001191
type: UnificationXref
id: HMDB0001191
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000179 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymine
stoichiometric coefficient: 1.0

Reference/UniProt Q84K35
type: UnificationXref
id: Q84K35
db: UniProt

Reference/UniProt Q9LK34
type: UnificationXref
id: Q9LK34
db: UniProt

ReactionCatalysis202616
type: Catalysis
controller: Alkaline-phosphatase-like family protein
controlled: Reaction212986
control type: ACTIVATION

ReactionCatalysis202618
type: Catalysis
controller: 5′-nucleotidase
controlled: Reaction212988
control type: ACTIVATION

ReactionCatalysis202613
type: Catalysis
controller: Probable apyrase 4
controlled: Reaction212983
control type: ACTIVATION

ReactionCatalysis202612
type: Catalysis
controller: Probable apyrase 4
controlled: Reaction212982
control type: ACTIVATION

ReactionCatalysis202614
type: Catalysis
controller: Alkaline-phosphatase-like family protein
controlled: Reaction212984
control type: ACTIVATION

ReactionCatalysis202611
type: Catalysis
controller: Nucleoside diphosphate kinase 1
controlled: Reaction212981
control type: ACTIVATION

ReactionCatalysis202610
type: Catalysis
controller: thymidylate kinase
controlled: Reaction212980
control type: ACTIVATION

Deoxyuridine triphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 65070
xref: Reference/BioCyc DUTP
xref: Reference/CAS 1173-82-6
xref: Reference/HMDB HMDB0001191
xref: Reference/ChEBI CHEBI 17625
xref: Reference/KEGG Compound C00460
xref: Reference/ChemSpider 58580
chemical formula: C9H15N2O14P3
molecular weight: 467.9736
structure: ChemicalStructure/PW C000927

ReactionCatalysis202628
type: Catalysis
controller: Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic
controlled: Reaction212998
control type: ACTIVATION

ReactionCatalysis202627
type: Catalysis
controller: Uridine nucleosidase 1
controlled: 3.2.2.3
control type: ACTIVATION

Reference/KEGG Compound C00106
type: UnificationXref
id: C00106
db: KEGG Compound

Reference/KEGG Compound C00105
type: UnificationXref
id: C00105
db: KEGG Compound

ReactionCatalysis202629
type: Catalysis
controller: Dihydropyrimidinase
controlled: Reaction212999
control type: ACTIVATION

Reference/PubChem-compound 6030
type: UnificationXref
id: 6030
db: PubChem-compound

ReactionCatalysis202624
type: Catalysis
controller: Uridine kinase-like protein 2, chloroplastic
controlled: Reaction212994
control type: ACTIVATION

Reference/PubChem-compound 6031
type: UnificationXref
id: 6031
db: PubChem-compound

ReactionCatalysis202626
type: Catalysis
controller: 5′-nucleotidase
controlled: Reaction212996
control type: ACTIVATION

Reference/CAS 800-73-7
type: UnificationXref
id: 800-73-7
db: CAS

ReactionCatalysis202625
type: Catalysis
controller: cytidine deaminase
controlled: 3.5.4.5
control type: ACTIVATION

Reference/BioCyc METHYLENE-THF
type: UnificationXref
id: METHYLENE-THF
db: BioCyc

ReactionCatalysis202622
type: Catalysis
controller: Uridine kinase-like protein 2, chloroplastic
controlled: 2.7.1.48,2.4.2.9
control type: ACTIVATION

dCMP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00239
xref: Reference/HMDB HMDB0001202
xref: Reference/CAS 1032-65-1
xref: Reference/BioCyc DCMP
xref: Reference/PubChem-compound 13945
xref: Reference/ChemSpider 13343
xref: Reference/ChEBI CHEBI 15918
chemical formula: C9H14N3O7P
molecular weight: 307.05695
structure: ChemicalStructure/PW C000937

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/ChEBI CHEBI 15033
type: UnificationXref
id: CHEBI:15033
db: ChEBI

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Uridine 5'-diphosphate

Protein/11643 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: cytidine deaminase
stoichiometric coefficient: 2.0

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Reference/KEGG Compound C00119
type: UnificationXref
id: C00119
db: KEGG Compound

Reference/BioCyc THYMIDINE
type: UnificationXref
id: THYMIDINE
db: BioCyc

ChemicalStructure/PW C000927
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00117
type: UnificationXref
id: C00117
db: KEGG Compound

dTDP
type: SmallMoleculeReference
xref: Reference/CAS 491-97-4
xref: Reference/ChemSpider 144320
xref: Reference/PubChem-compound 164628
xref: Reference/KEGG Compound C00363
xref: Reference/ChEBI CHEBI 18075
xref: Reference/HMDB HMDB0001274
xref: Reference/BioCyc TDP
chemical formula: C10H16N2O11P2
molecular weight: 402.02292
structure: ChemicalStructure/PW C000987

Reference/ChemSpider 388313
type: UnificationXref
id: 388313
db: ChemSpider

Reference/ChEBI CHEBI 18116
type: UnificationXref
id: CHEBI:18116
db: ChEBI

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Water
type: SmallMolecule
cellular location: Peroxisome
entity reference: Water

Pseudouridine 5'-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388535
xref: Reference/BioCyc PSEUDOURIDINE-5-P
xref: Reference/PubChem-compound 439424
xref: Reference/ChEBI CHEBI 18116
xref: Reference/HMDB HMDB0001271
xref: Reference/CAS 1157-60-4
xref: Reference/KEGG Compound C01168
chemical formula: C9H13N2O9P
molecular weight: 324.03586
structure: ChemicalStructure/PW C000984

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/CAS 1157-60-4
type: UnificationXref
id: 1157-60-4
db: CAS

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Dihydroorotate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Dihydroorotate

Reference/KEGG Compound C00112
type: UnificationXref
id: C00112
db: KEGG Compound

Uridine kinase-like protein 2, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Uridine kinase-like protein 2, chloroplastic

dTMP
type: SmallMolecule
cellular location: Nucleus
entity reference: dTMP

Uridine 5'-monophosphate
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Uridine 5'-monophosphate

dTDP
type: SmallMolecule
cellular location: Cytosol
entity reference: dTDP

Reference/ChemSpider 13118
type: UnificationXref
id: 13118
db: ChemSpider

Reference/ChemSpider 13117
type: UnificationXref
id: 13117
db: ChemSpider

ChemicalStructure/PW C000937
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/KEGG Compound C00363
type: UnificationXref
id: C00363
db: KEGG Compound

Reference/KEGG Compound C00121
type: UnificationXref
id: C00121
db: KEGG Compound

NADP
type: SmallMolecule
cellular location: Chloroplast
entity reference: NADP

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00365
type: UnificationXref
id: C00365
db: KEGG Compound

Reference/ChemSpider 388320
type: UnificationXref
id: 388320
db: ChemSpider

3-Ureidoisobutyrate
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Ureidoisobutyrate

Reference/ChemSpider 388535
type: UnificationXref
id: 388535
db: ChemSpider

Compound/PW C000204 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uracil
stoichiometric coefficient: 1.0

Cytidine monophosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Cytidine monophosphate

dCDP
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001245
xref: Reference/ChemSpider 132961
xref: Reference/KEGG Compound C00705
xref: Reference/ChEBI CHEBI 28846
xref: Reference/CAS 800-73-7
xref: Reference/PubChem-compound 150855
xref: Reference/BioCyc DCDP
chemical formula: C9H15N3O10P2
molecular weight: 387.02325
structure: ChemicalStructure/PW C000962

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Compound/PW C000056 Endoplasmic Reticulum/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrothymine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 7339
type: UnificationXref
id: 7339
db: PubChem-compound

Reference/UniProt Q8H1D8
type: UnificationXref
id: Q8H1D8
db: UniProt

Unknown
type: Protein
cellular location: Nucleus
entity reference: Unknown

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/KEGG Compound C00143
type: UnificationXref
id: C00143
db: KEGG Compound

Compound/PW C000057 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Ribonucleoside-diphosphate reductase large subunit
type: Protein
cellular location: Cytosol
entity reference: Ribonucleoside-diphosphate reductase large subunit

thymidylate kinase
type: Protein
cellular location: Nucleus
entity reference: thymidylate kinase

dTTP
type: SmallMolecule
cellular location: Cytosol
entity reference: dTTP

Reference/ChemSpider 13343
type: UnificationXref
id: 13343
db: ChemSpider

6.3.4.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000192 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Adenosine diphosphate
right: Cytidine triphosphate
spontaneous: false
EC number: 6.3.4.2
left: Ammonia
left: Adenosine triphosphate
left: Uridine triphosphate
name: Adenosine triphosphate + Ammonia + Uridine triphosphate → Adenosine diphosphate + Cytidine triphosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Hydroquinone
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002434
xref: Reference/ChemSpider 764
xref: Reference/PubChem-compound 785
xref: Reference/CAS 123-31-9
xref: Reference/BioCyc 236-TRICHLOROHYDROQUINONE
xref: Reference/ChEBI CHEBI 17594
xref: Reference/KEGG Compound C00530
chemical formula: C6H6O2
molecular weight: 110.03678
structure: ChemicalStructure/PW C001632

3.6.1.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000201 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000194 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: Uridine 5'-monophosphate
spontaneous: false
EC number: 3.6.1.5
left: Uridine 5'-diphosphate
left: Water
name: Uridine 5'-diphosphate + Water → Phosphate + Uridine 5'-monophosphate
conversion direction: LEFT_TO_RIGHT

2.7.4.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000194 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Uridine 5'-diphosphate
spontaneous: false
EC number: 2.7.4.14
left: Adenosine triphosphate
left: Uridine 5'-monophosphate
name: Adenosine triphosphate + Uridine 5'-monophosphate ↔ Adenosine diphosphate + Uridine 5'-diphosphate
conversion direction: REVERSIBLE

Reaction212892
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000201 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000192 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: Uridine 5'-diphosphate
spontaneous: false
left: Uridine triphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Uridine triphosphate → Phosphate + Uridine 5'-diphosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc DCDP
type: UnificationXref
id: DCDP
db: BioCyc

L-Glutamic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Glutamic acid

2.7.4.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000192 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: Uridine triphosphate
right: Adenosine diphosphate
spontaneous: false
EC number: 2.7.4.6
left: Uridine 5'-diphosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Uridine 5'-diphosphate ↔ Adenosine diphosphate + Uridine triphosphate
conversion direction: REVERSIBLE

3.6.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000192 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000194 Plant-Type Vacuole/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Plant-Type Vacuole/Stoichiometry/1.0
right: Uridine 5'-monophosphate
right: Pyrophosphate
spontaneous: false
EC number: 3.6.1.9
left: Uridine triphosphate
left: Water
name: Uridine triphosphate + Water → Pyrophosphate + Uridine 5'-monophosphate
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0002434
type: UnificationXref
id: HMDB0002434
db: HMDB

Reference/HMDB HMDB0000012
type: UnificationXref
id: HMDB0000012
db: HMDB

ChemicalStructure/PW C000053
type: ChemicalStructure
structure format: SMILES
structure data: O=C1CCNC(=O)N1

Peroxisome
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005777

Compound/PW C000414 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000014
type: UnificationXref
id: HMDB0000014
db: HMDB

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000056
type: ChemicalStructure
structure format: SMILES
structure data: CC1CNC(=O)NC1=O

Compound/PW C108990 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
stoichiometric coefficient: 1.0

dTDP
type: SmallMolecule
cellular location: Cell Membrane
entity reference: dTDP

Probable UMP-CMP kinase 1
type: Protein
cellular location: Nucleus
entity reference: Probable UMP-CMP kinase 1

Reference/PubChem-compound 649
type: UnificationXref
id: 649
db: PubChem-compound

dUDP
type: SmallMoleculeReference
xref: Reference/BioCyc DUDP
xref: Reference/PubChem-compound 145729
xref: Reference/CAS 4208-67-7
xref: Reference/KEGG Compound C01346
xref: Reference/HMDB HMDB0001000
xref: Reference/ChEBI CHEBI 28850
xref: Reference/ChemSpider 128553
chemical formula: C9H14N2O11P2
molecular weight: 388.0073
structure: ChemicalStructure/PW C000792

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

dCTP
type: SmallMoleculeReference
xref: Reference/CAS 2056-98-6
xref: Reference/PubChem-compound 65091
xref: Reference/ChEBI CHEBI 16311
xref: Reference/KEGG Compound C00458
xref: Reference/ChemSpider 58601
xref: Reference/HMDB HMDB0000998
xref: Reference/BioCyc DCTP
chemical formula: C9H16N3O13P3
molecular weight: 466.9896
structure: ChemicalStructure/PW C000790

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

dTTP
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: dTTP

Reference/KEGG Compound C00169
type: UnificationXref
id: C00169
db: KEGG Compound

Transport10795
type: Transport
participant stoichiometry: Compound/PW C000201 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000201 Cytoplasm/Stoichiometry/1.0
right: Uridine 5'-diphosphate
spontaneous: false
left: Uridine 5'-diphosphate
name: Uridine 5'-diphosphate (←) Transport: Arabidopsis thaliana, Cell, Cytoplasm to Arabidopsis thaliana, Cell, Nucleus
conversion direction: LEFT_TO_RIGHT

Compound/PW C000463 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen carbonate
stoichiometric coefficient: 1.0

Transport10790
type: Transport
participant stoichiometry: Compound/PW C108936 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108936 Mitochondrion/Stoichiometry/1.0
right: N-Carbamoyl-L-aspartate
spontaneous: false
left: N-Carbamoyl-L-aspartate
name: N-Carbamoyl-L-aspartate (→) Transport: Arabidopsis thaliana, Cell, Cytoplasm to Arabidopsis thaliana, Cell, Mitochondrion
conversion direction: LEFT_TO_RIGHT

Reference/CAS 58-97-9
type: UnificationXref
id: 58-97-9
db: CAS

Reference/ChemSpider 764
type: UnificationXref
id: 764
db: ChemSpider

Transport10792
type: Transport
participant stoichiometry: Compound/PW C000192 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000192 Nucleus/Stoichiometry/1.0
right: Uridine triphosphate
spontaneous: false
left: Uridine triphosphate
name: Uridine triphosphate (←) Transport: Arabidopsis thaliana, Cell, Cytosol to Arabidopsis thaliana, Cell, Nucleus
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Hydroquinone
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Hydroquinone

Amino acid kinase family protein
type: Protein
cellular location: Cytosol
entity reference: Amino acid kinase family protein

dCDP
type: SmallMolecule
cellular location: Cytosol
entity reference: dCDP

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Uridine 5'-diphosphate

Reference/HMDB HMDB0000262
type: UnificationXref
id: HMDB0000262
db: HMDB

Reference/CAS 65-46-3
type: UnificationXref
id: 65-46-3
db: CAS

Pentose phosphate pathway
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway112780
pathway component: SubPathwayInteraction112780
name: SubPathway

ChemicalStructure/PW C000061
type: ChemicalStructure
structure format: SMILES

Alanine, aspartate and glutamate metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway112782
pathway component: SubPathwayInteraction112782
name: SubPathway

Reference/UniProt O65896
type: UnificationXref
id: O65896
db: UniProt

Arginine biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway112781
pathway component: SubPathwayInteraction112781
name: SubPathway

Compound/PW C000194 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-monophosphate
stoichiometric coefficient: 1.0

Reference/BioCyc URACIL
type: UnificationXref
id: URACIL
db: BioCyc

Bifunctional dihydrofolate reductase-thymidylate synthase 1
type: Protein
cellular location: Cytosol
entity reference: Bifunctional dihydrofolate reductase-thymidylate synthase 1

Transport10789
type: Transport
participant stoichiometry: Compound/PW C108936 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108936 Chloroplast/Stoichiometry/1.0
right: N-Carbamoyl-L-aspartate
spontaneous: false
left: N-Carbamoyl-L-aspartate
name: N-Carbamoyl-L-aspartate (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cell, Cytoplasm
conversion direction: LEFT_TO_RIGHT

Cytidine monophosphate
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Cytidine monophosphate

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00178
type: UnificationXref
id: C00178
db: KEGG Compound

Compound/PW C000064 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

β-Alanine metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway112799
pathway component: SubPathwayInteraction112799
name: SubPathway

Quinone
type: SmallMoleculeReference
xref: Reference/ChemSpider 4489
xref: Reference/CAS 106-51-4
xref: Reference/KEGG Compound C00472
xref: Reference/ChEBI CHEBI 16509
xref: Reference/BioCyc CPD-8130
xref: Reference/PubChem-compound 4650
xref: Reference/HMDB HMDB0003364
chemical formula: C6H4O2
molecular weight: 108.021126
structure: ChemicalStructure/PW C001860

Reference/BioCyc AMMONIA
type: UnificationXref
id: AMMONIA
db: BioCyc

ChemicalStructure/PW C000035
type: ChemicalStructure
structure format: SMILES
structure data: N

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

dUDP
type: SmallMolecule
cellular location: Nucleus
entity reference: dUDP

Reference/CAS 590-55-6
type: UnificationXref
id: 590-55-6
db: CAS

Reference/HMDB HMDB0000273
type: UnificationXref
id: HMDB0000273
db: HMDB

Thioredoxin
type: ProteinReference
xref: Reference/ChEBI CHEBI 15033
organism: Arabidopsis thaliana

Compound/PW C001191 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribose 5-phosphate
stoichiometric coefficient: 1.0

Hydrogen carbonate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Hydrogen carbonate

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Thioredoxin disulfide
type: ProteinReference
xref: Reference/ChEBI CHEBI 18191
organism: Arabidopsis thaliana

Reference/HMDB HMDB0000288
type: UnificationXref
id: HMDB0000288
db: HMDB

Reference/BioCyc PSEUDOURIDINE-5-P
type: UnificationXref
id: PSEUDOURIDINE-5-P
db: BioCyc

Reference/ChemSpider 132961
type: UnificationXref
id: 132961
db: ChemSpider

Compound/PW C000035 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000280
type: UnificationXref
id: HMDB0000280
db: HMDB

ChemicalStructure/PW C000040
type: ChemicalStructure
structure format: SMILES
structure data: NCCC(O)=O

Reference/HMDB HMDB0000283
type: UnificationXref
id: HMDB0000283
db: HMDB

Reference/HMDB HMDB0000285
type: UnificationXref
id: HMDB0000285
db: HMDB

Dihydropyrimidinase
type: Protein
cellular location: Endoplasmic Reticulum
entity reference: Dihydropyrimidinase

CDP
type: SmallMolecule
cellular location: Nucleus
entity reference: CDP

Compound/PW C000053 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrouracil
stoichiometric coefficient: 1.0

Compound/PW C109002 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Ureidopropionate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/HMDB HMDB0000056
type: UnificationXref
id: HMDB0000056
db: HMDB

Reference/ChEBI CHEBI 18191
type: UnificationXref
id: CHEBI:18191
db: ChEBI

Uridine 5'-monophosphate
type: SmallMolecule
cellular location: Chloroplast
entity reference: Uridine 5'-monophosphate

ChemicalStructure/PW C001189
type: ChemicalStructure
structure format: SMILES

cytidine deaminase
type: Complex
component stoichiometry: Protein/11643 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: cytidine deaminase

Reference/HMDB HMDB0000051
type: UnificationXref
id: HMDB0000051
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0000295
type: UnificationXref
id: HMDB0000295
db: HMDB

Reference/ChemSpider 5807
type: UnificationXref
id: 5807
db: ChemSpider

Compound/PW C108944 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Orotate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5809
type: UnificationXref
id: 5809
db: ChemSpider

Reference/ChemSpider 5808
type: UnificationXref
id: 5808
db: ChemSpider

Reference/ChEBI CHEBI 15918
type: UnificationXref
id: CHEBI:15918
db: ChEBI

Reference/HMDB HMDB0000296
type: UnificationXref
id: HMDB0000296
db: HMDB

Reference/UniProt Q42586
type: UnificationXref
id: Q42586
db: UniProt

dCMP
type: SmallMolecule
cellular location: Cytosol
entity reference: dCMP

Uracil
type: SmallMolecule
cellular location: Cytosol
entity reference: Uracil

Compound/PW C001104 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Compound/PW C000170 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Compound/PW C000192 Plant-Type Vacuole/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

Reference/BioCyc RIBOSE-5P
type: UnificationXref
id: RIBOSE-5P
db: BioCyc

Compound/PW C108943 Mitochondrion/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroorotate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001191
type: ChemicalStructure
structure format: SMILES

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

Compound/PW C000056 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrothymine
stoichiometric coefficient: 1.0

NADPH
type: SmallMolecule
cellular location: Chloroplast
entity reference: NADPH

N-Carbamoyl-L-aspartate
type: SmallMoleculeReference
chemical formula: C5H8N2O5
molecular weight: 176.04332
structure: ChemicalStructure/PW C108936

6.3.5.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000862 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000463 Chloroplast/Stoichiometry/1.0
right: Phosphate
right: Carbamoyl phosphate
right: L-Glutamic acid
right: Adenosine diphosphate
spontaneous: false
EC number: 6.3.5.5
left: Hydrogen carbonate
left: Water
left: L-Glutamine
left: Adenosine triphosphate
name: Adenosine triphosphate + Hydrogen carbonate + L-Glutamine + Water → Adenosine diphosphate + Carbamoyl phosphate + L-Glutamic acid + Phosphate
conversion direction: LEFT_TO_RIGHT

2.1.3.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000862 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000123 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Chloroplast/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108936 Chloroplast/Stoichiometry/1.0
right: Phosphate
right: N-Carbamoyl-L-aspartate
spontaneous: false
EC number: 2.1.3.2
left: L-Aspartic acid
left: Carbamoyl phosphate
name: Carbamoyl phosphate + L-Aspartic acid → N-Carbamoyl-L-aspartate + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C108992 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

Reference/CAS 951-78-0
type: UnificationXref
id: 951-78-0
db: CAS

Reference/HMDB HMDB0000079
type: UnificationXref
id: HMDB0000079
db: HMDB

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic

Dihydroorotate
type: SmallMoleculeReference
chemical formula: C5H6N2O4
molecular weight: 158.03276
structure: ChemicalStructure/PW C108943

Orotate
type: SmallMoleculeReference
chemical formula: C5H4N2O4
molecular weight: 156.0171
structure: ChemicalStructure/PW C108944

Orotidine 5'-phosphate
type: SmallMoleculeReference
chemical formula: C10H13N2O11P
molecular weight: 368.0257
structure: ChemicalStructure/PW C108946

Reference/HMDB HMDB0000076
type: UnificationXref
id: HMDB0000076
db: HMDB

3.5.2.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C108936 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108943 Mitochondrion/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Mitochondrion/Stoichiometry/1.0
right: Water
right: Dihydroorotate
spontaneous: false
EC number: 3.5.2.3
left: N-Carbamoyl-L-aspartate
name: N-Carbamoyl-L-aspartate ↔ Dihydroorotate + Water
conversion direction: REVERSIBLE

1.3.5.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001860 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108943 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001632 Mitochondrial Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108944 Mitochondrial Inner Membrane/Stoichiometry/1.0
right: Hydroquinone
right: Orotate
spontaneous: false
EC number: 1.3.5.2
left: Dihydroorotate
left: Quinone
name: Dihydroorotate + Quinone ↔ Hydroquinone + Orotate
conversion direction: REVERSIBLE

2.4.2.10,4.1.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000190 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108944 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108946 Cytosol/Stoichiometry/1.0
right: Orotidine 5'-phosphate
right: Pyrophosphate
spontaneous: false
EC number: 2.4.2.10,4.1.1.23
left: Phosphoribosyl pyrophosphate
left: Orotate
name: Orotate + Phosphoribosyl pyrophosphate ↔ Orotidine 5'-phosphate + Pyrophosphate
conversion direction: REVERSIBLE

Reaction212889
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000194 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108946 Cytosol/Stoichiometry/1.0
right: Carbon dioxide
right: Uridine 5'-monophosphate
spontaneous: false
left: Orotidine 5'-phosphate
name: Orotidine 5'-phosphate → Carbon dioxide + Uridine 5'-monophosphate
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C001316 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Compound/PW C000792 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dUDP
stoichiometric coefficient: 1.0

Compound/PW C000987 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP
stoichiometric coefficient: 1.0

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

Reference/ChemSpider 749
type: UnificationXref
id: 749
db: ChemSpider

Reference/CAS 71-52-3
type: UnificationXref
id: 71-52-3
db: CAS

Reference/HMDB HMDB0000089
type: UnificationXref
id: HMDB0000089
db: HMDB

Compound/PW C108943 Mitochondrial Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroorotate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001178
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/ChEBI CHEBI 15901
type: UnificationXref
id: CHEBI:15901
db: ChEBI

Reference/CAS 66-22-8
type: UnificationXref
id: 66-22-8
db: CAS

Compound/PW C001178 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5,10-Methylene-THF
stoichiometric coefficient: 1.0

Compound/PW C108996 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTTP
stoichiometric coefficient: 1.0

Cytidine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Cytidine triphosphate

Dihydrofolic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydrofolic acid

Compound/PW C000201 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Uridine
type: SmallMolecule
cellular location: Chloroplast
entity reference: Uridine

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Protein/Generic28 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thioredoxin
stoichiometric coefficient: 1.0

2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate

Compound/PW C000187 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
cellular location: Chloroplast
entity reference: Hydrogen Ion

Compound/PW C001087 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dUMP
stoichiometric coefficient: 1.0

Reaction212946
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000057 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: CDP
spontaneous: false
left: Cytidine triphosphate
left: Water
name: Cytidine triphosphate + Water → CDP + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 239
type: UnificationXref
id: 239
db: PubChem-compound

Compound/PW C040034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reaction212947
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Cell Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cell Membrane/Stoichiometry/1.0
right: Phosphate
right: Cytidine monophosphate
spontaneous: false
left: CDP
left: Water
name: CDP + Water → Cytidine monophosphate + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C108992 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/UniProt Q9SJM7
type: UnificationXref
id: Q9SJM7
db: UniProt

dTTP
type: SmallMolecule
cellular location: Cell Membrane
entity reference: dTTP

2.7.4.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: CDP
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.4.6
left: Adenosine diphosphate
left: Cytidine triphosphate
name: Adenosine diphosphate + Cytidine triphosphate ↔ Adenosine triphosphate + CDP
conversion direction: REVERSIBLE

Reference/UniProt Q8H183
type: UnificationXref
id: Q8H183
db: UniProt

Reaction212951
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000064 Nucleus/Stoichiometry/1.0
right: CDP
right: Adenosine diphosphate
spontaneous: false
left: Cytidine monophosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Cytidine monophosphate ↔ Adenosine diphosphate + CDP
conversion direction: REVERSIBLE

1.17.4.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000962 Cytosol/Stoichiometry/1.0
participant stoichiometry: Protein/Generic27 Cytosol/Stoichiometry/1.0
participant stoichiometry: Protein/Generic28 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001189 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: dCDP
right: Thioredoxin disulfide
right: Water
spontaneous: false
EC number: 1.17.4.1
left: Thioredoxin
left: CDP
name: CDP + Thioredoxin → Thioredoxin disulfide + Water + dCDP
conversion direction: LEFT_TO_RIGHT

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reaction212955
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000962 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000790 Nucleus/Stoichiometry/1.0
right: dCTP
right: Adenosine diphosphate
spontaneous: false
left: dCDP
left: Adenosine triphosphate
name: Adenosine triphosphate + dCDP ↔ Adenosine diphosphate + dCTP
conversion direction: REVERSIBLE

Reaction212956
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000962 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000937 Nucleus/Stoichiometry/1.0
right: dCMP
right: Adenosine triphosphate
spontaneous: false
left: dCDP
left: Adenosine diphosphate
name: Adenosine diphosphate + dCDP ↔ Adenosine triphosphate + dCMP
conversion direction: REVERSIBLE

Reaction212957
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000008 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000937 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Deoxycytidine
spontaneous: false
left: dCMP
left: Water
name: Water + dCMP → Deoxycytidine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C000792
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ChemicalStructure/PW C000790
type: ChemicalStructure
structure format: SMILES

Compound/PW C108936 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Carbamoyl-L-aspartate
stoichiometric coefficient: 1.0

Compound/PW C000201 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Reaction212958
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000937 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Ammonia
right: dUMP
spontaneous: false
left: dCMP
left: Water
name: Water + dCMP → Ammonia + dUMP
conversion direction: LEFT_TO_RIGHT

Cytidine
type: SmallMolecule
cellular location: Cytosol
entity reference: Cytidine

Reaction212961
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine triphosphate
right: Deoxyuridine
spontaneous: false
left: Adenosine diphosphate
left: dUMP
name: Adenosine diphosphate + dUMP ← Adenosine triphosphate + Deoxyuridine
conversion direction: RIGHT_TO_LEFT

Reaction212962
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001087 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: Deoxyuridine
spontaneous: false
left: dUMP
left: Water
name: Water + dUMP → Deoxyuridine + Phosphate
conversion direction: LEFT_TO_RIGHT

3.5.4.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000008 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Ammonia
right: Deoxyuridine
spontaneous: false
EC number: 3.5.4.5
left: Hydrogen Ion
left: Deoxycytidine
left: Water
name: Deoxycytidine + Hydrogen Ion + Water → Ammonia + Deoxyuridine
conversion direction: LEFT_TO_RIGHT

Ammonia
type: SmallMolecule
cellular location: Cytosol
entity reference: Ammonia

5.4.99.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108986 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000937 Nucleus/Stoichiometry/1.0
right: Adenosine diphosphate
right: 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
spontaneous: false
EC number: 5.4.99.-
left: dCMP
left: Adenosine triphosphate
name: Adenosine triphosphate + dCMP → 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reaction212965
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108986 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108990 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: Adenosine diphosphate
right: 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
spontaneous: false
left: 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate
left: Adenosine triphosphate
name: 2'-Deoxy-5-hydroxymethylcytidine 5'-phosphate + Adenosine triphosphate → 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reaction212967
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108990 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108991 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
right: 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
right: Adenosine diphosphate
spontaneous: false
left: 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
left: Adenosine triphosphate
name: 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + Adenosine triphosphate → 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + Adenosine diphosphate
conversion direction: LEFT_TO_RIGHT

Reaction212968
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001087 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000792 Nucleus/Stoichiometry/1.0
right: Adenosine diphosphate
right: dUDP
spontaneous: false
left: dUMP
left: Adenosine triphosphate
name: Adenosine triphosphate + dUMP ↔ Adenosine diphosphate + dUDP
conversion direction: REVERSIBLE

Reference/PubChem-compound 164628
type: UnificationXref
id: 164628
db: PubChem-compound

Orotate
type: SmallMolecule
cellular location: Cytosol
entity reference: Orotate

Reference/UniProt Q05762
type: UnificationXref
id: Q05762
db: UniProt

Reference/HMDB HMDB0001533
type: UnificationXref
id: HMDB0001533
db: HMDB

Reaction212969
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000792 Nucleus/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000927 Nucleus/Stoichiometry/1.0
right: Adenosine diphosphate
right: Deoxyuridine triphosphate
spontaneous: false
left: dUDP
left: Adenosine triphosphate
name: Adenosine triphosphate + dUDP ↔ Adenosine diphosphate + Deoxyuridine triphosphate
conversion direction: REVERSIBLE

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Mitochondrion
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005739

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

D-Ribose
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Ribose

Reference/CAS 2056-98-6
type: UnificationXref
id: 2056-98-6
db: CAS

Reference/ChEBI CHEBI 17821
type: UnificationXref
id: CHEBI:17821
db: ChEBI

Reference/ChemSpider 144320
type: UnificationXref
id: 144320
db: ChemSpider

Compound/PW C001034 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C000064 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

Reference/BioCyc 236-TRICHLOROHYDROQUINONE
type: UnificationXref
id: 236-TRICHLOROHYDROQUINONE
db: BioCyc

SubPathwayInteraction112780
type: Interaction
name: SubPathwayReaction
name: SubPathway112780Reaction
participant: Phosphoribosyl pyrophosphate

Uridine triphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6133
xref: Reference/CAS 63-39-8
xref: Reference/ChemSpider 5903
xref: Reference/ChEBI CHEBI 15713
xref: Reference/KEGG Compound C00075
xref: Reference/HMDB HMDB0000285
xref: Reference/BioCyc UTP
chemical formula: C9H15N2O15P3
molecular weight: 483.96854
structure: ChemicalStructure/PW C000192

Water
type: SmallMolecule
cellular location: Mitochondrion
entity reference: Water

D-Ribose
type: SmallMoleculeReference
xref: Reference/ChemSpider 5575
xref: Reference/KEGG Compound C00121
xref: Reference/PubChem-compound 5779
xref: Reference/CAS 613-83-2
xref: Reference/BioCyc CPD-560
xref: Reference/HMDB HMDB0000283
xref: Reference/ChEBI CHEBI 47013
chemical formula: C5H10O5
molecular weight: 150.05283
structure: ChemicalStructure/PW C000191

Phosphoribosyl pyrophosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00119
xref: Reference/ChemSpider 7062
xref: Reference/CAS 7540-64-9
xref: Reference/HMDB HMDB0000280
xref: Reference/PubChem-compound 7339
xref: Reference/BioCyc PRPP
xref: Reference/ChEBI CHEBI 17111
chemical formula: C5H13O14P3
molecular weight: 389.9518
structure: ChemicalStructure/PW C000190

Reference/HMDB HMDB0001546
type: UnificationXref
id: HMDB0001546
db: HMDB

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/HMDB HMDB0001548
type: UnificationXref
id: HMDB0001548
db: HMDB

N-Carbamoyl-L-aspartate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: N-Carbamoyl-L-aspartate

Reference/GENE ONTOLOGY GO 0005886
type: UnificationXref
id: GO:0005886
db: GENE ONTOLOGY

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Thioredoxin disulfide
type: Protein
cellular location: Cytosol
entity reference: Thioredoxin disulfide

Uridine 5'-monophosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000288
xref: Reference/CAS 58-97-9
xref: Reference/KEGG Compound C00105
xref: Reference/PubChem-compound 6030
xref: Reference/BioCyc UMP
xref: Reference/ChEBI CHEBI 16695
xref: Reference/ChemSpider 5808
chemical formula: C9H13N2O9P
molecular weight: 324.03586
structure: ChemicalStructure/PW C000194

Indigoidine synthase A family protein
type: Protein
cellular location: Peroxisome
entity reference: Indigoidine synthase A family protein

Reference/CAS 50-89-5
type: UnificationXref
id: 50-89-5
db: CAS

Reference/BioCyc URIDINE
type: UnificationXref
id: URIDINE
db: BioCyc

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/GENE ONTOLOGY GO 0005634
type: UnificationXref
id: GO:0005634
db: GENE ONTOLOGY

Reference/CAS 7664-41-7
type: UnificationXref
id: 7664-41-7
db: CAS

Reference/BioCyc CDP
type: UnificationXref
id: CDP
db: BioCyc

Reference/CAS 107-95-9
type: UnificationXref
id: 107-95-9
db: CAS

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 222
type: UnificationXref
id: 222
db: PubChem-compound

Reference/BioCyc TDP
type: UnificationXref
id: TDP
db: BioCyc

thymidine kinase 1a
type: Protein
cellular location: Cytosol
entity reference: thymidine kinase 1a

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 3419
type: UnificationXref
id: 3419
db: PubChem-compound

Dihydroorotate dehydrogenase (quinone), mitochondrial
type: Protein
cellular location: Mitochondrial Inner Membrane
entity reference: Dihydroorotate dehydrogenase (quinone), mitochondrial

SubPathwayInteraction112799
type: Interaction
name: SubPathway112799Reaction
name: SubPathwayReaction
participant: β-Alanine

Thymine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17821
xref: Reference/ChemSpider 1103
xref: Reference/CAS 65-71-4
xref: Reference/PubChem-compound 1135
xref: Reference/HMDB HMDB0000262
xref: Reference/BioCyc THYMINE
xref: Reference/KEGG Compound C00178
chemical formula: C5H6N2O2
molecular weight: 126.04293
structure: ChemicalStructure/PW C000179

Thymine
type: SmallMolecule
cellular location: Cytosol
entity reference: Thymine

Reference/ChEBI CHEBI 16704
type: UnificationXref
id: CHEBI:16704
db: ChEBI

Reference/BioCyc DCMP
type: UnificationXref
id: DCMP
db: BioCyc

Compound/PW C000204 Peroxisome/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uracil
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15633
type: UnificationXref
id: CHEBI:15633
db: ChEBI

Reference/ChEBI CHEBI 15636
type: UnificationXref
id: CHEBI:15636
db: ChEBI

Compound/PW C000937 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dCMP
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-560
type: UnificationXref
id: CPD-560
db: BioCyc

Water
type: SmallMolecule
cellular location: Plant-Type Vacuole
entity reference: Water

SubPathwayInteraction112781
type: Interaction
name: SubPathway112781Reaction
name: SubPathwayReaction
participant: Carbamoyl phosphate

SubPathwayInteraction112782
type: Interaction
name: SubPathway112782Reaction
name: SubPathwayReaction
participant: L-Glutamine

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

Reference/ChEBI CHEBI 16958
type: UnificationXref
id: CHEBI:16958
db: ChEBI

Thymidine
type: SmallMoleculeReference
xref: Reference/BioCyc THYMIDINE
xref: Reference/ChEBI CHEBI 17748
xref: Reference/CAS 50-89-5
xref: Reference/PubChem-compound 5789
xref: Reference/ChemSpider 5585
xref: Reference/HMDB HMDB0000273
xref: Reference/KEGG Compound C00214
chemical formula: C10H14N2O5
molecular weight: 242.09027
structure: ChemicalStructure/PW C000187

Compound/PW C000194 Cell Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-monophosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17622
type: UnificationXref
id: CHEBI:17622
db: ChEBI

Reference/ChEBI CHEBI 17625
type: UnificationXref
id: CHEBI:17625
db: ChEBI

Endoplasmic Reticulum
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005783

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000962
type: ChemicalStructure
structure format: SMILES

dUMP
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17622
xref: Reference/ChemSpider 58574
xref: Reference/HMDB HMDB0001409
xref: Reference/CAS 964-26-1
xref: Reference/BioCyc DUMP
xref: Reference/PubChem-compound 65063
xref: Reference/KEGG Compound C00365
chemical formula: C9H13N2O8P
molecular weight: 308.04095
structure: ChemicalStructure/PW C001087

3-Ureidopropionate
type: SmallMolecule
cellular location: Endoplasmic Reticulum
entity reference: 3-Ureidopropionate

Reference/PubChem-compound 150855
type: UnificationXref
id: 150855
db: PubChem-compound

Reference/BioCyc DCTP
type: UnificationXref
id: DCTP
db: BioCyc

Reference/ChEBI CHEBI 15698
type: UnificationXref
id: CHEBI:15698
db: ChEBI

Reference/BioCyc CARBAMOYL-P
type: UnificationXref
id: CARBAMOYL-P
db: BioCyc

dCMP
type: SmallMolecule
cellular location: Nucleus
entity reference: dCMP

Reference/PubChem-compound 439424
type: UnificationXref
id: 439424
db: PubChem-compound

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

L-Aspartic acid
type: SmallMolecule
cellular location: Chloroplast
entity reference: L-Aspartic acid

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Compound/PW C000201 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine 5'-diphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 5585
type: UnificationXref
id: 5585
db: ChemSpider

Arabidopsis thaliana
type: BioSource
xref: Reference/TAXONOMY 3702

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Uridine 5'-monophosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Uridine 5'-monophosphate

Reference/ChEBI CHEBI 16509
type: UnificationXref
id: CHEBI:16509
db: ChEBI

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Nucleus
entity reference: Uridine 5'-diphosphate

Reference/ChemSpider 4489
type: UnificationXref
id: 4489
db: ChemSpider

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChemSpider 5575
type: UnificationXref
id: 5575
db: ChemSpider

Reference/BioCyc CPD-8130
type: UnificationXref
id: CPD-8130
db: BioCyc

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

N-Carbamoyl-L-aspartate
type: SmallMolecule
cellular location: Mitochondrion
entity reference: N-Carbamoyl-L-aspartate

Compound/PW C000204 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uracil
stoichiometric coefficient: 1.0

Reference/CAS 1173-82-6
type: UnificationXref
id: 1173-82-6
db: CAS

Compound/PW C000202 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine
stoichiometric coefficient: 1.0

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C108946 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Orotidine 5'-phosphate
stoichiometric coefficient: 1.0

Reference/UniProt Q9SU83
type: UnificationXref
id: Q9SU83
db: UniProt

Uridine triphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Uridine triphosphate

Compound/PW C000061 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine
stoichiometric coefficient: 1.0

Compound/PW C001189 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP
stoichiometric coefficient: 1.0

Compound/PW C000187 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine
stoichiometric coefficient: 1.0

CTP synthase
type: ProteinReference
organism: Arabidopsis thaliana

Compound/PW C108758 Chloroplast/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Phospho-alpha-D-ribose 1-diphosphate
stoichiometric coefficient: 1.0

Probable UMP-CMP kinase 1
type: ProteinReference
xref: Reference/UniProt Q8VY84
organism: Arabidopsis thaliana

Amino acid kinase family protein
type: ProteinReference
organism: Arabidopsis thaliana

Nucleoside diphosphate kinase 1
type: ProteinReference
xref: Reference/UniProt P39207
organism: Arabidopsis thaliana

Alkaline-phosphatase-like family protein
type: ProteinReference
xref: Reference/UniProt Q9SU83
organism: Arabidopsis thaliana

Uracil phosphoribosyltransferase, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Uracil phosphoribosyltransferase, chloroplastic

ChemicalStructure/PW C001860
type: ChemicalStructure
structure format: SMILES
structure data: O=C1C=CC(=O)C=C1

Probable apyrase 4
type: ProteinReference
xref: Reference/UniProt Q8H1D8
organism: Arabidopsis thaliana

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

ReactionCatalysis202606
type: Catalysis
controller: Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic
controlled: 1.3.1.2
control type: ACTIVATION

ReactionCatalysis202605
type: Catalysis
controller: Unknown
controlled: Reaction212975
control type: ACTIVATION

Reference/PubChem-compound 278
type: UnificationXref
id: 278
db: PubChem-compound

ReactionCatalysis202608
type: Catalysis
controller: Beta-ureidopropionase
controlled: 3.5.1.6
control type: ACTIVATION

ReactionCatalysis202607
type: Catalysis
controller: Dihydropyrimidinase
controlled: 3.5.2.2
control type: ACTIVATION

Thymidine
type: SmallMolecule
cellular location: Cytosol
entity reference: Thymidine

ReactionCatalysis202602
type: Catalysis
controller: Deoxyuridine 5'-triphosphate nucleotidohydrolase
controlled: 3.6.1.23
control type: ACTIVATION

ReactionCatalysis202601
type: Catalysis
controller: Bifunctional dihydrofolate reductase-thymidylate synthase 1
controlled: 1.5.1.3,2.1.1.45
control type: ACTIVATION

ReactionCatalysis202604
type: Catalysis
controller: thymidine kinase 1a
controlled: Reaction212974
control type: ACTIVATION

ReactionCatalysis202603
type: Catalysis
controller: 5′-nucleotidase
controlled: Reaction212973
control type: ACTIVATION

Reference/KEGG Compound C00881
type: UnificationXref
id: C00881
db: KEGG Compound

ReactionCatalysis202600
type: Catalysis
controller: Ribonucleoside-diphosphate reductase
controlled: Reaction212970
control type: ACTIVATION

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Carbamoyl-phosphate synthase large chain, chloroplastic
type: Protein
cellular location: Chloroplast
entity reference: Carbamoyl-phosphate synthase large chain, chloroplastic

Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17672
type: UnificationXref
id: CHEBI:17672
db: ChEBI

Ribonucleoside-diphosphate reductase large subunit
type: ProteinReference
xref: Reference/UniProt Q9SJ20
organism: Arabidopsis thaliana

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Reference/ChEBI CHEBI 27468
type: UnificationXref
id: CHEBI:27468
db: ChEBI

ChemicalStructure/PW C001632
type: ChemicalStructure
structure format: SMILES
structure data: OC1=CC=C(O)C=C1

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/ChEBI CHEBI 47013
type: UnificationXref
id: CHEBI:47013
db: ChEBI

Orotate
type: SmallMolecule
cellular location: Mitochondrial Inner Membrane
entity reference: Orotate

Reference/CAS 491-97-4
type: UnificationXref
id: 491-97-4
db: CAS

Reference/ChEBI CHEBI 16311
type: UnificationXref
id: CHEBI:16311
db: ChEBI

Reference/KEGG Compound C00415
type: UnificationXref
id: C00415
db: KEGG Compound

Reference/ChemSpider 58601
type: UnificationXref
id: 58601
db: ChemSpider

Uridine 5'-diphosphate
type: SmallMolecule
cellular location: Cell Membrane
entity reference: Uridine 5'-diphosphate

Cytidine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Cytidine triphosphate

ChemicalStructure/PW C000987
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

ChemicalStructure/PW C000984
type: ChemicalStructure
structure format: SMILES

Compound/PW C000792 Nucleus/Stoichiometry/1.0
type: Stoichiometry
physical entity: dUDP
stoichiometric coefficient: 1.0

Deoxyuridine 5'-triphosphate nucleotidohydrolase
type: ProteinReference
xref: Reference/UniProt Q9STG6
organism: Arabidopsis thaliana

Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9LVI9
organism: Arabidopsis thaliana

Dihydropyrimidinase
type: ProteinReference
xref: Reference/UniProt Q9FMP3
organism: Arabidopsis thaliana

Beta-ureidopropionase
type: ProteinReference
xref: Reference/UniProt Q8H183
organism: Arabidopsis thaliana

Ribonucleoside-diphosphate reductase small chain A
type: ProteinReference
xref: Reference/UniProt P50651
organism: Arabidopsis thaliana

Compound/PW C108992 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTMP
stoichiometric coefficient: 1.0

CMP/dCMP-type deaminase domain-containing protein
type: ProteinReference
organism: Arabidopsis thaliana

Bifunctional dihydrofolate reductase-thymidylate synthase 1
type: ProteinReference
xref: Reference/UniProt Q05762
organism: Arabidopsis thaliana

Compound/PW C000987 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP
stoichiometric coefficient: 1.0

Orotidine 5'-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Orotidine 5'-phosphate

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/CAS 63-39-8
type: UnificationXref
id: 63-39-8
db: CAS

Reference/ChEBI CHEBI 17659
type: UnificationXref
id: CHEBI:17659
db: ChEBI

Reference/CAS 65-71-4
type: UnificationXref
id: 65-71-4
db: CAS

Reference/KEGG Compound C00429
type: UnificationXref
id: C00429
db: KEGG Compound

Deoxycytidine
type: SmallMolecule
cellular location: Cytosol
entity reference: Deoxycytidine

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Uridine nucleosidase 1
type: ProteinReference
xref: Reference/UniProt Q9SJM7
organism: Arabidopsis thaliana

Uracil phosphoribosyltransferase, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9M336
organism: Arabidopsis thaliana

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Indigoidine synthase A family protein
type: ProteinReference
xref: Reference/UniProt Q84K35
organism: Arabidopsis thaliana

Cytidine
type: SmallMolecule
cellular location: Chloroplast
entity reference: Cytidine

Uridine kinase-like protein 2, chloroplastic
type: ProteinReference
xref: Reference/UniProt Q9LK34
organism: Arabidopsis thaliana

Reference/CAS 4300-28-1
type: UnificationXref
id: 4300-28-1
db: CAS