Phosphomethylpyrimidine synthase, chloroplastic
Thiamine biosynthetic bifunctional enzyme TH1, chloroplastic
Thiamine thiazole synthase, chloroplastic
2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate
2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate
4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate
4-Amino-5-hydroxymethyl-2-methylpyrimidine phosphate
4-Amino-5-hydroxymethyl-2-methylpyrimidine (→) Transport: Arabidopsis thaliana, Cell, Cytoplasm to Arabidopsis thaliana, Cell, Chloroplast
Thiamine monophosphate (→) Transport: Arabidopsis thaliana, Cell, Chloroplast to Arabidopsis thaliana, Cytosol
5-Aminoimidazole ribonucleotide + S-Adenosylmethionine → 4-Amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'-Deoxyadenosine + Carbon monoxide + Formic acid + L-Methionine
4-Amino-5-hydroxymethyl-2-methylpyrimidine phosphate + Adenosine triphosphate → 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + Adenosine diphosphate
2-[(2R,5Z)-2-Carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 2-(2-Carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-Amino-5-hydroxymethyl-2-methylpyrimidine diphosphate + 4-Methyl-5-(2-phosphooxyethyl)thiazole → Carbon dioxide + Diphosphoric acid + Thiamine monophosphate
Thiamine monophosphate + Water → Phosphate + Thiamine
4-Amino-5-aminomethyl-2-methylpyrimidine + Water → 4-Amino-5-hydroxymethyl-2-methylpyrimidine + Ammonia
4-Amino-5-hydroxymethyl-2-methylpyrimidine + Adenosine triphosphate → 4-Amino-5-hydroxymethyl-2-methylpyrimidine phosphate + Adenosine diphosphate
5-(2-Hydroxyethyl)-4-methylthiazole + Adenosine triphosphate → 4-Methyl-5-(2-phosphooxyethyl)thiazole + Adenosine diphosphate
Adenosine triphosphate + Thiamine → Adenosine monophosphate + Thiamine pyrophosphate
Adenosine monophosphate + Thiamine pyrophosphate → Thiamine triphosphate
Thiamine pyrophosphate + Water → Phosphate + Thiamine monophosphate
Glycine + NAD + [ADP-thiazole synthase]-L-cysteine → ADP-5-ethyl-4-methylthiazole-2-carboxylate + Niacinamide + Water + [ADP-thiazole synthase]-dehydroalanine
N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + Water → 4-Amino-5-aminomethyl-2-methylpyrimidine + Formic acid