Mitochondrial carnitine/acylcarnitine carrier protein
Malonyl-CoA → Acetyl-CoA + Carbon dioxide
Malonyl-CoA inhibits Carnitine O-palmitoyltransferase 1
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoic acid
Acetyl-CoA + L-Carnitine ↔ Coenzyme A + L-Acetylcarnitine
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoic acid + Adenosine triphosphate + Coenzyme A → 7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoyl-CoA + Adenosine monophosphate + Pyrophosphate
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoyl-CoA + L-Carnitine ↔ 7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoylcarnitine + Coenzyme A
Carnitine O-palmitoyltransferase 1, liver isoform
Carnitine O-palmitoyltransferase 2, mitochondrial
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoylcarnitine + Coenzyme A → 7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoyl-CoA + L-Carnitine
Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
L-Carnitine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cytosol
Acylcarnitine 7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoylcarnitine
Malonyl-CoA decarboxylase, mitochondrial
Long-chain fatty acid transport protein 1
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoic acid (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell
7-[(2R,4aR,5S,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoylcarnitine (→) Transport: Homo sapiens, Cell, Mitochondrial Intermembrane Space to Homo sapiens, Liver, Mitochondrial Matrix