Reference/PathWhiz PW002364
type: UnificationXref
id: PW002364
db: PathWhiz

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/KEGG Compound C00318
type: UnificationXref
id: C00318
db: KEGG Compound

Transport12346
type: Transport
participant stoichiometry: Compound/PW C110159/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110159 Extracellular Space/Stoichiometry/1.0
right: 3-methylpentacosanoic acid
spontaneous: false
left: 3-methylpentacosanoic acid
name: 3-methylpentacosanoic acid (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cell
conversion direction: LEFT_TO_RIGHT

TransportCatalysis2419
type: Catalysis
controller: Mitochondrial carnitine/acylcarnitine carrier protein
controlled: Transport12347
control type: ACTIVATION

TransportCatalysis2418
type: Catalysis
controller: Long-chain fatty acid transport protein 1
controlled: Transport12346
control type: ACTIVATION

Transport12347
type: Transport
participant stoichiometry: Compound/PW C110158 Mitochondrial Intermembrane Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110158 Mitochondrial Matrix/Stoichiometry/1.0
right: 3-Methylpentacosanoylcarnitine
spontaneous: false
left: 3-Methylpentacosanoylcarnitine
name: 3-Methylpentacosanoylcarnitine (→) Transport: Homo sapiens, Cell, Mitochondrial Intermembrane Space to Homo sapiens, Liver, Mitochondrial Matrix
conversion direction: LEFT_TO_RIGHT

direct_interaction
type: InteractionVocabulary

L-Carnitine
type: SmallMolecule
cellular location: Extracellular Space
entity reference: L-Carnitine

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Acetyl-CoA carboxylase 1
type: Protein
entity reference: Acetyl-CoA carboxylase 1

Reference/SMPDB SMP0123816
type: UnificationXref
id: SMP0123816
db: SMPDB

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

TransportCatalysis2422
type: Catalysis
controller: Solute carrier family 22 member 5
controlled: Transport11315
control type: ACTIVATION

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/PathWhiz PW000173
type: UnificationXref
id: PW000173
db: PathWhiz

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Mitochondrial carnitine/acylcarnitine carrier protein
type: Protein
entity reference: Mitochondrial carnitine/acylcarnitine carrier protein

Solute carrier family 22 member 5
type: Protein
entity reference: Solute carrier family 22 member 5

L-Carnitine
type: SmallMolecule
entity reference: L-Carnitine

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reaction1248
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000911/Stoichiometry/1.0
right: Malonyl-CoA
spontaneous: false
left: Acetyl-CoA
name: Acetyl-CoA → Malonyl-CoA
conversion direction: LEFT_TO_RIGHT

L-Carnitine
type: SmallMoleculeReference
xref: Reference/BioCyc CARNITINE
xref: Reference/ChEBI CHEBI 16347
xref: Reference/PubChem-compound 10917
xref: Reference/CAS 541-15-1
xref: Reference/KEGG Compound C00318
xref: Reference/HMDB HMDB0000062
xref: Reference/ChemSpider 10455
chemical formula: C7H15NO3
molecular weight: 161.1052
structure: ChemicalStructure/PW C000044

4.1.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000911/Stoichiometry/1.0
right: Carbon dioxide
right: Acetyl-CoA
spontaneous: false
EC number: 4.1.1.9
left: Malonyl-CoA
name: Malonyl-CoA → Acetyl-CoA + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

L-Acetylcarnitine
type: SmallMoleculeReference
xref: Reference/CAS 3040-38-8
xref: Reference/PubChem-compound 1
xref: Reference/ChemSpider 21243783
xref: Reference/HMDB HMDB0000201
xref: Reference/KEGG Compound C02571
xref: Reference/BioCyc (-)o-acetylcarnitine
xref: Reference/ChEBI CHEBI 73024
chemical formula: C9H17NO4
molecular weight: 203.11575
structure: ChemicalStructure/PW C000129

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

3-Methylpentacosanoyl-CoA
type: SmallMolecule
entity reference: 3-Methylpentacosanoyl-CoA

Adenosine monophosphate
type: SmallMolecule
entity reference: Adenosine monophosphate

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

L-Carnitine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Carnitine

ReactionCatalysis962
type: Catalysis
controller: Acetyl-CoA carboxylase 1
controlled: Reaction1248
control type: ACTIVATION

ReactionCatalysis1101
type: Catalysis
controller: Carnitine O-acetyltransferase
controlled: 2.3.1.7
control type: ACTIVATION

3-Methylpentacosanoylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Intermembrane Space
entity reference: 3-Methylpentacosanoylcarnitine

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

ReactionCatalysis289
type: Catalysis
controller: Carnitine O-palmitoyltransferase 1
controlled: 2.3.1.21
control type: ACTIVATION

ReactionCatalysis961
type: Catalysis
controller: Malonyl-CoA decarboxylase, mitochondrial
controlled: 4.1.1.9
control type: ACTIVATION

ReactionCatalysis288
type: Catalysis
controller: Long-chain-fatty-acid--CoA ligase 1
controlled: 6.2.1.3
control type: ACTIVATION

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Interaction3511
type: MolecularInteraction
interaction type: direct_interaction
name: Malonyl-CoA inhibits Carnitine O-palmitoyltransferase 1
participant: Carnitine O-palmitoyltransferase 1
participant: Malonyl-CoA

Compound/PW C000044 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

3-methylpentacosanoic acid
type: SmallMolecule
entity reference: 3-methylpentacosanoic acid

Compound/PW C110158/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Methylpentacosanoylcarnitine
stoichiometric coefficient: 1.0

3-Methylpentacosanoylcarnitine
type: SmallMolecule
entity reference: 3-Methylpentacosanoylcarnitine

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/CAS 3040-38-8
type: UnificationXref
id: 3040-38-8
db: CAS

Reference/HMDB HMDB0000201
type: UnificationXref
id: HMDB0000201
db: HMDB

2.3.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000129/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044/Stoichiometry/1.0
right: Coenzyme A
right: L-Acetylcarnitine
spontaneous: false
EC number: 2.3.1.7
left: L-Carnitine
left: Acetyl-CoA
name: Acetyl-CoA + L-Carnitine ↔ Coenzyme A + L-Acetylcarnitine
conversion direction: REVERSIBLE

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Compound/PW C000129/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Acetylcarnitine
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0002296
type: UnificationXref
id: SMP0002296
db: SMPDB

Compound/PW C000032/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Reference/CAS 541-15-1
type: UnificationXref
id: 541-15-1
db: CAS

ChemicalStructure/PW C000129
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C

3-Methylpentacosanoylcarnitine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0241022
chemical formula: C33H65NO4
molecular weight: 539.49133
structure: ChemicalStructure/PW C110158

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

3-methylpentacosanoic acid
type: SmallMoleculeReference
chemical formula: C26H52O2
molecular weight: 396.39673
structure: ChemicalStructure/PW C110159

Carnitine O-acetyltransferase
type: ProteinReference
xref: Reference/UniProt P43155

SubPathwayInteraction115132
type: Interaction
name: SubPathway115132Reaction
name: SubPathwayReaction
participant: Acetyl-CoA

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

SubPathwayInteraction115133
type: Interaction
name: SubPathwayReaction
name: SubPathway115133Reaction
participant: Acetyl-CoA
participant: 3-Methylpentacosanoyl-CoA

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Compound/PW C110159 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-methylpentacosanoic acid
stoichiometric coefficient: 1.0

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Long-chain-fatty-acid--CoA ligase 1
type: Protein
entity reference: Long-chain-fatty-acid--CoA ligase 1

Carnitine O-palmitoyltransferase 1, liver isoform
type: Protein
entity reference: Carnitine O-palmitoyltransferase 1, liver isoform

3-Methylpentacosanoyl-CoA
type: SmallMoleculeReference
chemical formula: C47H86N7O17P3S
molecular weight: 1145.5013
structure: ChemicalStructure/PW C110160

Carnitine O-palmitoyltransferase 2, mitochondrial
type: Protein
entity reference: Carnitine O-palmitoyltransferase 2, mitochondrial

Reference/ChEBI CHEBI 15531
type: UnificationXref
id: CHEBI:15531
db: ChEBI

6.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000032/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110159/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110160/Stoichiometry/1.0
right: 3-Methylpentacosanoyl-CoA
right: Adenosine monophosphate
right: Pyrophosphate
spontaneous: false
EC number: 6.2.1.3
left: Coenzyme A
left: 3-methylpentacosanoic acid
left: Adenosine triphosphate
name: 3-methylpentacosanoic acid + Adenosine triphosphate + Coenzyme A → 3-Methylpentacosanoyl-CoA + Adenosine monophosphate + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reaction215615
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110158/Stoichiometry/1.0
right: L-Carnitine
right: 3-Methylpentacosanoyl-CoA
spontaneous: false
left: Coenzyme A
left: 3-Methylpentacosanoylcarnitine
name: 3-Methylpentacosanoylcarnitine + Coenzyme A → 3-Methylpentacosanoyl-CoA + L-Carnitine
conversion direction: LEFT_TO_RIGHT

2.3.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C110160/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044/Stoichiometry/1.0
participant stoichiometry: Compound/PW C110158/Stoichiometry/1.0
right: Coenzyme A
right: 3-Methylpentacosanoylcarnitine
spontaneous: false
EC number: 2.3.1.21
left: 3-Methylpentacosanoyl-CoA
left: L-Carnitine
name: 3-Methylpentacosanoyl-CoA + L-Carnitine ↔ 3-Methylpentacosanoylcarnitine + Coenzyme A
conversion direction: REVERSIBLE

Reference/UniProt Q13085
type: UnificationXref
id: Q13085
db: UniProt

Carnitine O-palmitoyltransferase 1
type: Complex
component stoichiometry: Protein/303/Stoichiometry/6.0
component: Carnitine O-palmitoyltransferase 1, liver isoform

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway115133
pathway component: SubPathwayInteraction115133
xref: Reference/PathWhiz PW000173
xref: Reference/SMPDB SMP0000482
name: SubPathway

Reference/UniProt P23786
type: UnificationXref
id: P23786
db: UniProt

Reference/GENE ONTOLOGY GO 0005758
type: UnificationXref
id: GO:0005758
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005759
type: UnificationXref
id: GO:0005759
db: GENE ONTOLOGY

3-methylpentacosanoic acid
type: SmallMolecule
cellular location: Extracellular Space
entity reference: 3-methylpentacosanoic acid

Carnitine O-acetyltransferase
type: Protein
entity reference: Carnitine O-acetyltransferase

Solute carrier family 22 member 5
type: ProteinReference
xref: Reference/UniProt O76082

Transport11315
type: Transport
participant stoichiometry: Compound/PW C000044 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000044 Extracellular Space/Stoichiometry/1.0
right: L-Carnitine
spontaneous: false
left: L-Carnitine
name: L-Carnitine (→) Transport: Homo sapiens, Extracellular Space to Homo sapiens, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Mitochondrial carnitine/acylcarnitine carrier protein
type: ProteinReference
xref: Reference/UniProt O43772

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/ChEBI CHEBI 73024
type: UnificationXref
id: CHEBI:73024
db: ChEBI

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Extracellular Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005615

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 1
type: UnificationXref
id: 1
db: PubChem-compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Malonyl-CoA decarboxylase, mitochondrial
type: Protein
entity reference: Malonyl-CoA decarboxylase, mitochondrial

Reference/BioCyc CARNITINE
type: UnificationXref
id: CARNITINE
db: BioCyc

Compound/PW C110160/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Methylpentacosanoyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Malonyl-CoA decarboxylase, mitochondrial
type: ProteinReference
xref: Reference/UniProt O95822

Reference/UniProt O95822
type: UnificationXref
id: O95822
db: UniProt

ChemicalStructure/PW C000911
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/UniProt P43155
type: UnificationXref
id: P43155
db: UniProt

Reference/KEGG Compound C02571
type: UnificationXref
id: C02571
db: KEGG Compound

Reference/UniProt O76082
type: UnificationXref
id: O76082
db: UniProt

Reference/GENE ONTOLOGY GO 0005615
type: UnificationXref
id: GO:0005615
db: GENE ONTOLOGY

Compound/PW C000911/Stoichiometry/1.0
type: Stoichiometry
physical entity: Malonyl-CoA
stoichiometric coefficient: 1.0

Reference/UniProt P33121
type: UnificationXref
id: P33121
db: UniProt

Carnitine O-palmitoyltransferase 1, liver isoform
type: ProteinReference
xref: Reference/UniProt P50416

Protein/303/Stoichiometry/6.0
type: Stoichiometry
physical entity: Carnitine O-palmitoyltransferase 1, liver isoform
stoichiometric coefficient: 6.0

Carnitine O-palmitoyltransferase 2, mitochondrial
type: ProteinReference
xref: Reference/UniProt P23786

Long-chain-fatty-acid--CoA ligase 1
type: ProteinReference
xref: Reference/UniProt P33121

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/UniProt Q6PCB7
type: UnificationXref
id: Q6PCB7
db: UniProt

Mitochondrial Matrix
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005759

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway115132
pathway component: SubPathwayInteraction115132
xref: Reference/PathWhiz PW002364
xref: Reference/SMPDB SMP0002296
name: SubPathway

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

3-Methylpentacosanoyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Methylpentacosanoyl-CoA
name: SubPathwayInput

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/SMPDB SMP0000482
type: UnificationXref
id: SMP0000482
db: SMPDB

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Compound/PW C000044 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C110158
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 10917
type: UnificationXref
id: 10917
db: PubChem-compound

Reference/ChemSpider 10455
type: UnificationXref
id: 10455
db: ChemSpider

Reference/ChemSpider 10213
type: UnificationXref
id: 10213
db: ChemSpider

Long-chain fatty acid transport protein 1
type: Protein
entity reference: Long-chain fatty acid transport protein 1

Compound/PW C110158 Mitochondrial Intermembrane Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Methylpentacosanoylcarnitine
stoichiometric coefficient: 1.0

Acetyl-CoA carboxylase 1
type: ProteinReference
xref: Reference/UniProt Q13085

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Homo sapiens
type: BioSource
xref: Reference/TAXONOMY 9606

ReactionCatalysis203665
type: Catalysis
controller: Carnitine O-palmitoyltransferase 2, mitochondrial
controlled: Reaction215615
control type: ACTIVATION

Reference/CAS 524-14-1
type: UnificationXref
id: 524-14-1
db: CAS

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C110159
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCCCCCCCCCCCCC(C)CC(O)=O

3-Methylpentacosanoylcarnitine
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: 3-Methylpentacosanoylcarnitine

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

ChemicalStructure/PW C110160
type: ChemicalStructure
structure format: SMILES

Reference/UniProt O43772
type: UnificationXref
id: O43772
db: UniProt

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

ChemicalStructure/PW C000044
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)C[C@H](O)CC([O-])=O

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/HMDB HMDB0241022
type: UnificationXref
id: HMDB0241022
db: HMDB

Acylcarnitine 3-Methylpentacosanoylcarnitine
type: Pathway
pathway order: PathwayEnzymeReaction/2482904
pathway order: PathwayEnzymeReaction/2482903
pathway order: PathwayEnzymeReaction/2482902
pathway order: PathwayEnzymeReaction/2482901
pathway order: PathwayInteraction/3511
pathway order: PathwaySubPathway/115133
pathway order: PathwaySubPathway/115132
pathway order: PathwayEnzymeReaction/2482900
pathway order: PathwayTransport/2482906
pathway order: PathwayEnzymeReaction/2482899
pathway order: PathwayTransport/2482905
pathway order: PathwayTransport/2482907
pathway component: 6.2.1.3
pathway component: ReactionCatalysis289
pathway component: ReactionCatalysis961
pathway component: Reaction215615
pathway component: ReactionCatalysis288
pathway component: 2.3.1.21
pathway component: TransportCatalysis2422
pathway component: ReactionCatalysis203665
pathway component: Transport11315
pathway component: Interaction3511
pathway component: Transport12346
pathway component: TransportCatalysis2419
pathway component: TransportCatalysis2418
pathway component: Transport12347
pathway component: Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids
pathway component: 2.3.1.7
pathway component: Reaction1248
pathway component: TCA Cycle
pathway component: 4.1.1.9
pathway component: ReactionCatalysis962
pathway component: ReactionCatalysis1101
xref: Reference/PathWhiz PW125272
xref: Reference/SMPDB SMP0123816
organism: Homo sapiens

Reference/TAXONOMY 9606
type: UnificationXref
id: 9606
db: TAXONOMY

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/BioCyc (-)o-acetylcarnitine
type: UnificationXref
id: (-)o-acetylcarnitine
db: BioCyc

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Long-chain fatty acid transport protein 1
type: ProteinReference
xref: Reference/UniProt Q6PCB7

Reference/UniProt P50416
type: UnificationXref
id: P50416
db: UniProt

Compound/PW C110159/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-methylpentacosanoic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00083
type: UnificationXref
id: C00083
db: KEGG Compound

Mitochondrial Intermembrane Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005758

Compound/PW C110158 Mitochondrial Matrix/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Methylpentacosanoylcarnitine
stoichiometric coefficient: 1.0

Malonyl-CoA
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15531
xref: Reference/KEGG Compound C00083
xref: Reference/BioCyc MALONYL-COA
xref: Reference/CAS 524-14-1
xref: Reference/HMDB HMDB0001175
xref: Reference/PubChem-compound 10663
xref: Reference/ChemSpider 10213
chemical formula: C24H38N7O19P3S
molecular weight: 853.1156
structure: ChemicalStructure/PW C000911

Reference/ChEBI CHEBI 16347
type: UnificationXref
id: CHEBI:16347
db: ChEBI

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Compound/PW C000044/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Carnitine
stoichiometric coefficient: 1.0

L-Acetylcarnitine
type: SmallMolecule
entity reference: L-Acetylcarnitine

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/HMDB HMDB0000062
type: UnificationXref
id: HMDB0000062
db: HMDB

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Malonyl-CoA
type: SmallMolecule
entity reference: Malonyl-CoA

Reference/PubChem-compound 10663
type: UnificationXref
id: 10663
db: PubChem-compound

Reference/ChemSpider 21243783
type: UnificationXref
id: 21243783
db: ChemSpider

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/PathWhiz PW125272
type: UnificationXref
id: PW125272
db: PathWhiz

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Acetyl-CoA
type: SmallMolecule
cellular location: Mitochondrial Matrix
entity reference: Acetyl-CoA
name: SubPathwayOutput
name: SubPathwayInput

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/BioCyc MALONYL-COA
type: UnificationXref
id: MALONYL-COA
db: BioCyc

Reference/HMDB HMDB0001175
type: UnificationXref
id: HMDB0001175
db: HMDB