Lanosterol + 3 NADPH + 3 Oxygen → 4,4-Dimethylcholesta-8,14,24-trienol + Formic acid + 3 NADP + 4 Water
Itraconazole (→) Transport: Homo sapiens, Liver, Hepatocyte, Endoplasmic Reticulum Membrane to Homo sapiens, Blood Vessel
Hydroxyitraconazole (→) Transport: Homo sapiens, Liver, Hepatocyte, Endoplasmic Reticulum Membrane to Homo sapiens, Blood Vessel
Itraconazole (→) Transport: Homo sapiens, Stomach to Homo sapiens, Intestine
Itraconazole + NADPH + Oxygen → Hydrogen Ion + Hydroxyitraconazole + NADP + Water
Itraconazole (→) Transport: Homo sapiens, Blood Vessel to Homo sapiens, Liver, Hepatocyte, Endoplasmic Reticulum Membrane
Itraconazole (→) Transport: Homo sapiens, Intestine to Homo sapiens, Intestine, Epithelial Cell
Canalicular multispecific organic anion transporter 2
Itraconazole (→) Transport: Homo sapiens, Intestine, Epithelial Cell to Homo sapiens, Blood Vessel
Itraconazole inhibits Lanosterol 14-alpha demethylase
Itraconazole inhibits Cytochrome P450 3A5
Itraconazole inhibits Cytochrome P450 3A7
Itraconazole inhibits Cytochrome P450 3A4
Itraconazole inhibits Cytochrome P450 2B6
Itraconazole inhibits Cytochrome P450 2E1