fused 4'-phosphopantothenoylcysteine decarboxylase and phosphopantothenoylcysteine synthetase
3-methyl-2-oxobutanoate hydroxymethyltransferase
(R)-pantoate + Adenosine triphosphate + β-Alanine → Adenosine monophosphate + Hydrogen Ion + Pantothenic acid + Pyrophosphate
Adenosine triphosphate + Pantothenic acid → Adenosine diphosphate + D-4'-Phosphopantothenate + Hydrogen Ion
2-dehydropantoate + Hydrogen Ion + NADPH → (R)-pantoate + NADP
Hydrogen Ion + L-Aspartic acid → Carbon dioxide + β-Alanine
Adenosine triphosphate + Dephospho-CoA + Hydrogen Ion → 2'-(5-Triphosphoribosyl)-3'-dephospho-CoA + Adenine
2,3-Dihydroxyisovaleric acid ↔ Water + 2 α-Ketoisovaleric acid
4'-phosphopantetheine + Adenosine triphosphate + Hydrogen Ion → Dephospho-CoA + Pyrophosphate
Adenosine triphosphate + Dephospho-CoA → Adenosine diphosphate + Coenzyme A + Hydrogen Ion
Cytidine triphosphate + D-4'-Phosphopantothenate + L-Cysteine → 4'-Phosphopantothenoylcysteine + Cytidine monophosphate + Hydrogen Ion + Pyrophosphate
4'-Phosphopantothenoylcysteine + Hydrogen Ion → 4'-phosphopantetheine + Carbon dioxide
5,10-Methylene-THF + Water + α-Ketoisovaleric acid → 2-dehydropantoate + Tetrahydrofolic acid