Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reaction2902
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040928/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001938/Stoichiometry/1.0
right: 2-iminopropanoate
spontaneous: true
left: 2-Aminoacrylic acid
name: 2-Aminoacrylic acid → 2-iminopropanoate
conversion direction: LEFT_TO_RIGHT

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reaction2903
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040928/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Ammonium
right: Pyruvic acid
spontaneous: true
left: Water
left: 2-iminopropanoate
left: Hydrogen Ion
name: 2-iminopropanoate + Hydrogen Ion + Water → Ammonium + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

L-Serine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Serine

Reference/PubChem-compound 123991
type: UnificationXref
id: 123991
db: PubChem-compound

DL-O-Phosphoserine
type: SmallMolecule
cellular location: Inner Membrane
entity reference: DL-O-Phosphoserine

NADH
type: SmallMolecule
entity reference: NADH

Reference/PathWhiz PW400776
type: UnificationXref
id: PW400776
db: PathWhiz

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Acetyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetyl-CoA
name: SubPathwayInput

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Unknown
type: Protein
entity reference: Unknown

Reference/ChEBI CHEBI 17115
type: UnificationXref
id: CHEBI:17115
db: ChEBI

2-Aminoacrylic acid
type: SmallMolecule
entity reference: 2-Aminoacrylic acid

NAD
type: SmallMolecule
entity reference: NAD

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Compound/PW C001214/Stoichiometry/1.0
type: Stoichiometry
physical entity: DL-O-Phosphoserine
stoichiometric coefficient: 1.0

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Serine Biosynthesis and Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/5687301
pathway order: PathwayEnzymeReaction/5687302
pathway order: PathwayTransport/5687309
pathway order: PathwayEnzymeReaction/5687300
pathway order: PathwayEnzymeReaction/5687305
pathway order: PathwayEnzymeReaction/5687306
pathway order: PathwayEnzymeReaction/5687303
pathway order: PathwayEnzymeReaction/5687304
pathway order: PathwayTransport/5687310
pathway order: PathwayEnzymeReaction/5687307
pathway order: PathwayEnzymeReaction/5687308
pathway order: PathwaySubPathway/394946
pathway order: PathwaySubPathway/394945
pathway component: 3.1.3.3
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: Transport48368
pathway component: Reaction2902
pathway component: Reaction2903
pathway component: TCA Cycle
pathway component: TransportCatalysis33013
pathway component: Transport51735
pathway component: TransportCatalysis30058
pathway component: ReactionCatalysis667713
pathway component: ReactionCatalysis667646
pathway component: ReactionCatalysis667712
pathway component: ReactionCatalysis667711
pathway component: ReactionCatalysis667710
pathway component: ReactionCoupledTransport746
pathway component: 1.1.1.95
pathway component: 2.6.1.52
pathway component: 1.2.4.1
pathway component: ReactionCatalysis667709
pathway component: 4.3.1.17
pathway component: ReactionCoupledTransportCatalysis808
xref: Reference/PathWhiz PW400776
xref: Reference/SMPDB SMP0391373
organism: Bacteroides sp. 2_2_4

DL-O-Phosphoserine
type: SmallMoleculeReference
xref: Reference/ChemSpider 104
xref: Reference/BioCyc 3-P-SERINE
xref: Reference/HMDB HMDB0001721
xref: Reference/PubChem-compound 106
xref: Reference/ChEBI CHEBI 37712
xref: Reference/CAS 17885-08-4
xref: Reference/KEGG Compound C01005
chemical formula: C3H8NO6P
molecular weight: 185.00893
structure: ChemicalStructure/PW C001214

Pyruvate dehydrogenase complex
type: Complex
component stoichiometry: Protein/28973/Stoichiometry/60.0
component: Unknown

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

3-phosphoserine aminotransferase / phosphohydroxythreonine aminotransferase
type: Complex
component stoichiometry: Protein/28973/Stoichiometry/2.0
component: Unknown

D-3-phosphoglycerate dehydrogenase / α-ketoglutarate reductase
type: Complex
component stoichiometry: Protein/28973/Stoichiometry/4.0
component: Unknown

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/CAS 17885-08-4
type: UnificationXref
id: 17885-08-4
db: CAS

ChemicalStructure/PW C040928
type: ChemicalStructure
structure format: SMILES
structure data: CC(=N)C([O-])=O

Transport51735
type: Transport
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000120 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: L-Serine
spontaneous: false
left: Hydrogen Ion
left: L-Serine
name: L-Serine (→), Hydrogen Ion (→) Transport: Bacteroides sp. 2_2_4, Periplasmic Space to Bacteroides sp. 2_2_4, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ReactionCatalysis667646
type: Catalysis
controller: Unknown
controlled: 3.1.3.3
control type: ACTIVATION

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 5736
type: UnificationXref
id: 5736
db: ChemSpider

Protein/28973/Stoichiometry/60.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 60.0

Phosphohydroxypyruvic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001024
xref: Reference/PubChem-compound 105
xref: Reference/ChemSpider 103
xref: Reference/CAS 3913-50-6
xref: Reference/ChEBI CHEBI 30933
xref: Reference/KEGG Compound C03232
xref: Reference/BioCyc 3-P-HYDROXYPYRUVATE
chemical formula: C3H5O7P
molecular weight: 183.9773
structure: ChemicalStructure/PW C000810

phosphonate ABC transporter
type: Complex
component stoichiometry: Protein/28973 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Reference/ChemSpider 704
type: UnificationXref
id: 704
db: ChemSpider

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/BioCyc SER
type: UnificationXref
id: SER
db: BioCyc

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/CAS 1948-56-7
type: UnificationXref
id: 1948-56-7
db: CAS

Unknown
type: Protein
cellular location: Inner Membrane
entity reference: Unknown

Ammonium
type: SmallMolecule
entity reference: Ammonium

Reference/CAS 3913-50-6
type: UnificationXref
id: 3913-50-6
db: CAS

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Compound/PW C001214 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: DL-O-Phosphoserine
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Reference/KEGG Compound C00597
type: UnificationXref
id: C00597
db: KEGG Compound

Compound/PW C000120 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

2-iminopropanoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 77456
chemical formula: C3H4NO2
molecular weight: 86.02475
structure: ChemicalStructure/PW C040928

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

ReactionCatalysis667709
type: Catalysis
controller: D-3-phosphoglycerate dehydrogenase / α-ketoglutarate reductase
controlled: 1.1.1.95
control type: ACTIVATION

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

ReactionCoupledTransportCatalysis808
type: Catalysis
controller: phosphonate ABC transporter
controlled: ReactionCoupledTransport746
control type: ACTIVATION

Reference/PathWhiz PW000779
type: UnificationXref
id: PW000779
db: PathWhiz

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

3-Phosphoglyceric acid
type: SmallMolecule
entity reference: 3-Phosphoglyceric acid

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

ChemicalStructure/PW C000810
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C(=O)COP(O)(O)=O

Reference/HMDB HMDB0003609
type: UnificationXref
id: HMDB0003609
db: HMDB

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Compound/PW C040928/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-iminopropanoate
stoichiometric coefficient: 1.0

ReactionCatalysis667713
type: Catalysis
controller: Unknown
controlled: 4.3.1.17
control type: ACTIVATION

Bacteroides sp. 2_2_4
type: BioSource
xref: Reference/TAXONOMY 469590

ReactionCatalysis667712
type: Catalysis
controller: Unknown
controlled: 4.3.1.17
control type: ACTIVATION

ReactionCatalysis667711
type: Catalysis
controller: Pyruvate dehydrogenase complex
controlled: 1.2.4.1
control type: ACTIVATION

ReactionCatalysis667710
type: Catalysis
controller: 3-phosphoserine aminotransferase / phosphohydroxythreonine aminotransferase
controlled: 2.6.1.52
control type: ACTIVATION

Unknown
type: ProteinReference

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/PubChem-compound 105
type: UnificationXref
id: 105
db: PubChem-compound

2-Aminoacrylic acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 110510
xref: Reference/CAS 1948-56-7
xref: Reference/KEGG Compound C02218
xref: Reference/HMDB HMDB0003609
xref: Reference/PubChem-compound 123991
xref: Reference/ChEBI CHEBI 17123
chemical formula: C3H5NO2
molecular weight: 87.03203
structure: ChemicalStructure/PW C001938

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway394945
pathway component: SubPathwayInteraction394945
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Transport48368
type: Transport
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000120 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: L-Serine
spontaneous: false
left: Hydrogen Ion
left: L-Serine
name: L-Serine (→), Hydrogen Ion (→) Transport: Bacteroides sp. 2_2_4, Periplasmic Space to Bacteroides sp. 2_2_4, Cytosol
conversion direction: LEFT_TO_RIGHT

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/PubChem-compound 106
type: UnificationXref
id: 106
db: PubChem-compound

Protein/28973 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway394946
pathway component: SubPathwayInteraction394946
xref: Reference/SMPDB SMP0000802
xref: Reference/PathWhiz PW000779
name: SubPathway

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/ChEBI CHEBI 17123
type: UnificationXref
id: CHEBI:17123
db: ChEBI

Reference/PubChem-compound 5951
type: UnificationXref
id: 5951
db: PubChem-compound

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/BioCyc 3-P-HYDROXYPYRUVATE
type: UnificationXref
id: 3-P-HYDROXYPYRUVATE
db: BioCyc

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Compound/PW C000644/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Phosphoglyceric acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

TransportCatalysis30058
type: Catalysis
controller: Unknown
controlled: Transport48368
control type: ACTIVATION

Reference/ChemSpider 104
type: UnificationXref
id: 104
db: ChemSpider

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

ChemicalStructure/PW C000120
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CO)C(O)=O

Reference/ChemSpider 103
type: UnificationXref
id: 103
db: ChemSpider

ChemicalStructure/PW C001214
type: ChemicalStructure
structure format: SMILES
structure data: NC(COP(O)(O)=O)C(O)=O

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ChemicalStructure/PW C001938
type: ChemicalStructure
structure format: SMILES
structure data: NC(=C)C(O)=O

Reference/SMPDB SMP0000802
type: UnificationXref
id: SMP0000802
db: SMPDB

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/KEGG Compound C02218
type: UnificationXref
id: C02218
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine triphosphate

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/KEGG Compound C01005
type: UnificationXref
id: C01005
db: KEGG Compound

Reference/HMDB HMDB0000807
type: UnificationXref
id: HMDB0000807
db: HMDB

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

DL-O-Phosphoserine
type: SmallMolecule
cellular location: Cytosol
entity reference: DL-O-Phosphoserine

Phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Phosphate

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Protein/28973/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

Compound/PW C000120 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

3-Phosphoglyceric acid
type: SmallMoleculeReference
xref: Reference/BioCyc G3P
xref: Reference/PubChem-compound 724
xref: Reference/ChEBI CHEBI 17050
xref: Reference/ChemSpider 704
xref: Reference/CAS 820-11-1
xref: Reference/KEGG Compound C00597
xref: Reference/HMDB HMDB0000807
chemical formula: C3H7O7P
molecular weight: 185.99294
structure: ChemicalStructure/PW C000644

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Compound/PW C001938 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Aminoacrylic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

TransportCatalysis33013
type: Catalysis
controller: Unknown
controlled: Transport51735
control type: ACTIVATION

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

2-iminopropanoate
type: SmallMolecule
entity reference: 2-iminopropanoate

Reference/ChEBI CHEBI 30933
type: UnificationXref
id: CHEBI:30933
db: ChEBI

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/SMPDB SMP0391373
type: UnificationXref
id: SMP0391373
db: SMPDB

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C000810/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphohydroxypyruvic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00065
type: UnificationXref
id: C00065
db: KEGG Compound

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/ChEBI CHEBI 17050
type: UnificationXref
id: CHEBI:17050
db: ChEBI

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

3-Phosphoglyceric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Phosphoglyceric acid
name: SubPathwayOutput

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/PubChem-compound 724
type: UnificationXref
id: 724
db: PubChem-compound

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChEBI CHEBI 37712
type: UnificationXref
id: CHEBI:37712
db: ChEBI

ChemicalStructure/PW C000644
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C(O)=O

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Phosphohydroxypyruvic acid
type: SmallMolecule
entity reference: Phosphohydroxypyruvic acid

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/HMDB HMDB0001024
type: UnificationXref
id: HMDB0001024
db: HMDB

Reference/ChEBI CHEBI 77456
type: UnificationXref
id: CHEBI:77456
db: ChEBI

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

1.1.1.95
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000810/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000644/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: Phosphohydroxypyruvic acid
spontaneous: false
EC number: 1.1.1.95
left: 3-Phosphoglyceric acid
left: NAD
name: 3-Phosphoglyceric acid + NAD → Hydrogen Ion + NADH + Phosphohydroxypyruvic acid
conversion direction: LEFT_TO_RIGHT

2.6.1.52
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000810/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001214/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: Oxoglutaric acid
right: DL-O-Phosphoserine
spontaneous: false
EC number: 2.6.1.52
left: L-Glutamic acid
left: Phosphohydroxypyruvic acid
name: L-Glutamic acid + Phosphohydroxypyruvic acid → DL-O-Phosphoserine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

1.2.4.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
right: NADH
right: Carbon dioxide
right: Acetyl-CoA
spontaneous: false
EC number: 1.2.4.1
left: Coenzyme A
left: Pyruvic acid
left: NAD
name: Coenzyme A + NAD + Pyruvic acid → Acetyl-CoA + Carbon dioxide + NADH
conversion direction: LEFT_TO_RIGHT

4.3.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001938 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: Water
right: 2-Aminoacrylic acid
spontaneous: false
EC number: 4.3.1.17
left: L-Serine
name: L-Serine → 2-Aminoacrylic acid + Hydrogen Ion + Water
conversion direction: LEFT_TO_RIGHT

4.3.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001938 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: Water
right: 2-Aminoacrylic acid
spontaneous: false
EC number: 4.3.1.17
left: L-Serine
name: L-Serine → 2-Aminoacrylic acid + Hydrogen Ion + Water
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

L-Serine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Serine

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

3.1.3.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001214 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Phosphate
right: L-Serine
spontaneous: false
EC number: 3.1.3.3
left: DL-O-Phosphoserine
left: Water
name: DL-O-Phosphoserine + Water → L-Serine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/CAS 56-45-1
type: UnificationXref
id: 56-45-1
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C03232
type: UnificationXref
id: C03232
db: KEGG Compound

DL-O-Phosphoserine
type: SmallMolecule
entity reference: DL-O-Phosphoserine

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Reference/BioCyc G3P
type: UnificationXref
id: G3P
db: BioCyc

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ReactionCoupledTransport746
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001214 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: Adenosine diphosphate
right: Hydrogen Ion
right: DL-O-Phosphoserine
spontaneous: false
left: Water
left: Adenosine triphosphate
left: DL-O-Phosphoserine
name: Adenosine triphosphate + DL-O-Phosphoserine + Water → Adenosine diphosphate + DL-O-Phosphoserine + Hydrogen Ion + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Protein/28973/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

L-Serine
type: SmallMoleculeReference
xref: Reference/ChemSpider 5736
xref: Reference/ChEBI CHEBI 17115
xref: Reference/CAS 56-45-1
xref: Reference/KEGG Compound C00065
xref: Reference/PubChem-compound 5951
xref: Reference/HMDB HMDB0000187
xref: Reference/BioCyc SER
chemical formula: C3H7NO3
molecular weight: 105.042595
structure: ChemicalStructure/PW C000120

Reference/HMDB HMDB0000187
type: UnificationXref
id: HMDB0000187
db: HMDB

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

SubPathwayInteraction394946
type: Interaction
name: SubPathway394946Reaction
name: SubPathwayReaction
participant: Acetyl-CoA

SubPathwayInteraction394945
type: Interaction
name: SubPathway394945Reaction
name: SubPathwayReaction
participant: 3-Phosphoglyceric acid

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Reference/TAXONOMY 469590
type: UnificationXref
id: 469590
db: TAXONOMY

Compound/PW C001938/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Aminoacrylic acid
stoichiometric coefficient: 1.0

2-Aminoacrylic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 2-Aminoacrylic acid

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/HMDB HMDB0001721
type: UnificationXref
id: HMDB0001721
db: HMDB

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Compound/PW C001214 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: DL-O-Phosphoserine
stoichiometric coefficient: 1.0

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 110510
type: UnificationXref
id: 110510
db: ChemSpider

Reference/BioCyc 3-P-SERINE
type: UnificationXref
id: 3-P-SERINE
db: BioCyc

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Adenosine diphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine diphosphate

Reference/CAS 820-11-1
type: UnificationXref
id: 820-11-1
db: CAS

Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0