2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid
Adenosine triphosphate + L-Aspartic acid + L-Glutamine + Water → Adenosine monophosphate + Hydrogen Ion + L-Asparagine + L-Glutamic acid + Pyrophosphate
Adenosine triphosphate + Ammonium + L-Aspartic acid → Adenosine monophosphate + Hydrogen Ion + L-Asparagine + Pyrophosphate
Escherichia coli (strain K12 / MC4100 / BW2952)
L-Asparagine + Water → Ammonium + L-Aspartic acid