Ketoleucine + L-Glutamic acid → L-Leucine + Oxoglutaric acid
3-Methyl-2-oxovaleric acid + Acetyl-CoA + Water → 2-Isopropylmalic acid + Coenzyme A + Hydrogen Ion
2-Isopropylmalic acid → Isopropylmaleate + Water
Isopropylmaleate + Water → 3-Isopropylmalate
3-Isopropylmalate + NAD → 2-Isopropyl-3-oxosuccinate + Hydrogen Ion + NADH
branched-chain amino-acid aminotransferase
L-Leucine (→) Transport: Escherichia coli E24377A, Cytosol to Escherichia coli E24377A, Periplasmic Space
2-Isopropyl-3-oxosuccinate + Hydrogen Ion → Carbon dioxide + Ketoleucine