Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6140
type: UnificationXref
id: 6140
db: PubChem-compound

Phenylalanine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway446208
pathway component: SubPathwayInteraction446208
xref: Reference/PathWhiz PW000807
xref: Reference/SMPDB SMP0000827
name: SubPathway

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/ChemSpider 1001
type: UnificationXref
id: 1001
db: ChemSpider

Reference/UniProt S3J095
type: UnificationXref
id: S3J095
db: UniProt

Reference/ChEBI CHEBI 16134
type: UnificationXref
id: CHEBI:16134
db: ChEBI

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

Reference/CAS 63-91-2
type: UnificationXref
id: 63-91-2
db: CAS

Compound/PW C001065/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxygen
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Ammonia
type: SmallMoleculeReference
xref: Reference/BioCyc AMMONIA
xref: Reference/CAS 7664-41-7
xref: Reference/HMDB HMDB0000051
xref: Reference/PubChem-compound 222
xref: Reference/KEGG Compound C00014
xref: Reference/ChEBI CHEBI 16134
xref: Reference/ChemSpider 217
chemical formula: H3N
molecular weight: 17.026548
structure: ChemicalStructure/PW C000035

Reference/PubChem-compound 6919011
type: UnificationXref
id: 6919011
db: PubChem-compound

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C042923 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-phenylalanine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C02505
type: UnificationXref
id: C02505
db: KEGG Compound

Chorismate Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway446209
pathway component: SubPathwayInteraction446209
xref: Reference/SMPDB SMP0000836
xref: Reference/PathWhiz PW000816
name: SubPathway

Protein/48143/Stoichiometry/2.0
type: Stoichiometry
physical entity: T-protein
stoichiometric coefficient: 2.0

D-phenylalanine
type: SmallMolecule
entity reference: D-phenylalanine

D-phenylalanine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: D-phenylalanine

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Phenylalanine Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/6172971
pathway order: PathwayEnzymeReaction/6172970
pathway order: PathwayTransport/6172979
pathway order: PathwayTransport/6172978
pathway order: PathwayTransport/6172980
pathway order: PathwaySubPathway/446209
pathway order: PathwayEnzymeReaction/6172977
pathway order: PathwayEnzymeReaction/6172976
pathway order: PathwaySubPathway/446208
pathway order: PathwayEnzymeReaction/6172975
pathway order: PathwayEnzymeReaction/6172973
pathway order: PathwayEnzymeReaction/6172972
pathway component: ReactionCatalysis928458
pathway component: ReactionCatalysis671061
pathway component: ReactionCatalysis928459
pathway component: ReactionCatalysis671062
pathway component: Phenylalanine Biosynthesis
pathway component: Chorismate Biosynthesis
pathway component: Transport50100
pathway component: ReactionCatalysis928460
pathway component: ReactionCatalysis671059
pathway component: TransportCatalysis31533
pathway component: Reaction675118
pathway component: 5.4.99.5
pathway component: 2.6.1.57
pathway component: ReactionCatalysis671060
pathway component: 1.11.1.21
pathway component: 2.6.1.1
pathway component: 1.4.99.1
pathway component: TransportCatalysis48458
pathway component: Transport67906
pathway component: Transport67905
pathway component: TransportCatalysis48459
xref: Reference/PathWhiz PW437950
xref: Reference/SMPDB SMP0424373
organism: Cedecea davisae DSM 4568

Compound/PW C042923 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-phenylalanine
stoichiometric coefficient: 1.0

Compound/PW C000035/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

D-phenylalanine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6919011
chemical formula: C9H11NO2
molecular weight: 165.07898
structure: ChemicalStructure/PW C042923

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Protein/29199/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/ChemSpider 952
type: UnificationXref
id: 952
db: ChemSpider

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Protein/37299/Stoichiometry/2.0
type: Stoichiometry
physical entity: FAD dependent oxidoreductase
stoichiometric coefficient: 2.0

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Ammonia
type: SmallMolecule
entity reference: Ammonia

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Unknown
type: ProteinReference

Phenylpyruvic acid
type: SmallMoleculeReference
xref: Reference/CAS 156-06-9
xref: Reference/ChEBI CHEBI 30851
xref: Reference/ChemSpider 972
xref: Reference/BioCyc PHENYL-PYRUVATE
xref: Reference/PubChem-compound 997
xref: Reference/HMDB HMDB0000205
xref: Reference/KEGG Compound C00166
chemical formula: C9H8O3
molecular weight: 164.04735
structure: ChemicalStructure/PW C000131

Starvation-sensing protein RspA
type: Protein
entity reference: Starvation-sensing protein RspA

Compound/PW C000104/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Phenylalanine
stoichiometric coefficient: 1.0

T-protein
type: Protein
entity reference: T-protein

Aminotransferase
type: ProteinReference
xref: Reference/UniProt S3K5J4

aminodeoxychorismate lyase
type: Protein
entity reference: aminodeoxychorismate lyase

phenylalanine transaminase:aspC
type: Complex
component stoichiometry: Protein/33697/Stoichiometry/2.0
component: Aminotransferase

phenylalanine transaminase:ilvE
type: Complex
component stoichiometry: Protein/48144/Stoichiometry/6.0
component: aminodeoxychorismate lyase

D-phenylalanine
type: SmallMolecule
cellular location: Cytosol
entity reference: D-phenylalanine

Starvation-sensing protein RspA
type: ProteinReference
xref: Reference/UniProt S3ITF6

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

aminodeoxychorismate lyase
type: ProteinReference
xref: Reference/UniProt S3J095

Reference/PubChem-compound 1028
type: UnificationXref
id: 1028
db: PubChem-compound

Reference/HMDB HMDB0000205
type: UnificationXref
id: HMDB0000205
db: HMDB

Compound/PW C006723/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Phenylacetamide
stoichiometric coefficient: 1.0

T-protein
type: ProteinReference
xref: Reference/UniProt S3IPF5

TransportCatalysis48458
type: Catalysis
controller: Unknown
controlled: Transport67905
control type: ACTIVATION

TransportCatalysis48459
type: Catalysis
controller: Unknown
controlled: Transport67906
control type: ACTIVATION

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/BioCyc CPD-6641
type: UnificationXref
id: CPD-6641
db: BioCyc

Aminotransferase
type: Protein
entity reference: Aminotransferase

Reference/ChemSpider 217
type: UnificationXref
id: 217
db: ChemSpider

ChemicalStructure/PW C000131
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C(=O)CC1=CC=CC=C1

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Prephenate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16666
xref: Reference/CAS 126-49-8
xref: Reference/PubChem-compound 1028
xref: Reference/BioCyc PREPHENATE
xref: Reference/KEGG Compound C00254
xref: Reference/HMDB HMDB0012283
xref: Reference/ChemSpider 1001
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007823

Reference/BioCyc PREPHENATE
type: UnificationXref
id: PREPHENATE
db: BioCyc

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Oxygen
type: SmallMolecule
entity reference: Oxygen

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/UniProt S3IV45
type: UnificationXref
id: S3IV45
db: UniProt

Reference/KEGG Compound C00007
type: UnificationXref
id: C00007
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

ReactionCatalysis928460
type: Catalysis
controller: D-amino acid dehydrogenase
controlled: 1.4.99.1
control type: ACTIVATION

D-amino acid dehydrogenase
type: Complex
component stoichiometry: Protein/37299/Stoichiometry/2.0
component: FAD dependent oxidoreductase

Reference/BioCyc PHENYL-PYRUVATE
type: UnificationXref
id: PHENYL-PYRUVATE
db: BioCyc

chorismate mutase:pheA
type: Complex
component stoichiometry: Protein/48143/Stoichiometry/2.0
component: T-protein

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 7664-41-7
type: UnificationXref
id: 7664-41-7
db: CAS

ReactionCatalysis928458
type: Catalysis
controller: phenylalanine aminotransferase
controlled: 2.6.1.57
control type: ACTIVATION

ReactionCatalysis928459
type: Catalysis
controller: Catalase Peroxidase
controlled: 1.11.1.21
control type: ACTIVATION

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00254
type: UnificationXref
id: C00254
db: KEGG Compound

Reference/PathWhiz PW437950
type: UnificationXref
id: PW437950
db: PathWhiz

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

ChemicalStructure/PW C000104
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC1=CC=CC=C1)C(O)=O

Reference/PubChem-compound 222
type: UnificationXref
id: 222
db: PubChem-compound

Reference/KEGG Compound C00014
type: UnificationXref
id: C00014
db: KEGG Compound

Prephenate
type: SmallMolecule
entity reference: Prephenate

Cedecea davisae DSM 4568
type: BioSource
xref: Reference/TAXONOMY 566551

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Reference/UniProt S3K5J4
type: UnificationXref
id: S3K5J4
db: UniProt

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/TAXONOMY 566551
type: UnificationXref
id: 566551
db: TAXONOMY

Aminotransferase
type: Protein
entity reference: Aminotransferase

Reference/PubChem-compound 7680
type: UnificationXref
id: 7680
db: PubChem-compound

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/ChemSpider 7397
type: UnificationXref
id: 7397
db: ChemSpider

2-Phenylacetamide
type: SmallMolecule
entity reference: 2-Phenylacetamide

2-Phenylacetamide
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0010715
xref: Reference/CAS 103-81-1
xref: Reference/PubChem-compound 7680
xref: Reference/KEGG Compound C02505
xref: Reference/ChEBI CHEBI 16562
xref: Reference/ChemSpider 7397
chemical formula: C8H9NO
molecular weight: 135.06842
structure: ChemicalStructure/PW C006723

Reference/HMDB HMDB0010715
type: UnificationXref
id: HMDB0010715
db: HMDB

Reference/UniProt S3IPF5
type: UnificationXref
id: S3IPF5
db: UniProt

ChemicalStructure/PW C042923
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC1=CC=CC=C1)C(O)=O

Transport50100
type: Transport
participant stoichiometry: Compound/PW C000104 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
right: L-Phenylalanine
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: L-Phenylalanine
name: L-Phenylalanine (→), Hydrogen Ion (→) Transport: Cedecea davisae DSM 4568, Periplasmic Space to Cedecea davisae DSM 4568, Cytosol
conversion direction: LEFT_TO_RIGHT

FAD dependent oxidoreductase
type: Protein
entity reference: FAD dependent oxidoreductase

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Water
type: SmallMolecule
entity reference: Water

Transport67906
type: Transport
participant stoichiometry: Compound/PW C000104 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000104 Cytosol/Stoichiometry/1.0
right: L-Phenylalanine
spontaneous: false
left: L-Phenylalanine
name: L-Phenylalanine (→) Transport: Cedecea davisae DSM 4568, Cytosol to Cedecea davisae DSM 4568, Periplasmic Space
conversion direction: LEFT_TO_RIGHT

Transport67905
type: Transport
participant stoichiometry: Compound/PW C042923 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042923 Periplasmic Space/Stoichiometry/1.0
right: D-phenylalanine
spontaneous: false
left: D-phenylalanine
name: D-phenylalanine (→) Transport: Cedecea davisae DSM 4568, Cytosol to Cedecea davisae DSM 4568, Periplasmic Space
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16666
type: UnificationXref
id: CHEBI:16666
db: ChEBI

Protein/33697/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aminotransferase
stoichiometric coefficient: 2.0

Reference/PubChem-compound 997
type: UnificationXref
id: 997
db: PubChem-compound

Reference/KEGG Compound C00166
type: UnificationXref
id: C00166
db: KEGG Compound

L-Phenylalanine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Phenylalanine

ReactionCatalysis671059
type: Catalysis
controller: chorismate mutase:pheA
controlled: 5.4.99.5
control type: ACTIVATION

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

Reference/SMPDB SMP0424373
type: UnificationXref
id: SMP0424373
db: SMPDB

ChemicalStructure/PW C006723
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)CC1=CC=CC=C1

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Protein/48144/Stoichiometry/6.0
type: Stoichiometry
physical entity: aminodeoxychorismate lyase
stoichiometric coefficient: 6.0

Compound/PW C007823/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prephenate
stoichiometric coefficient: 1.0

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

ReactionCatalysis671061
type: Catalysis
controller: phenylalanine transaminase:ilvE
controlled: 2.6.1.1
control type: ACTIVATION

L-Phenylalanine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Phenylalanine

ReactionCatalysis671062
type: Catalysis
controller: phenylalanine transaminase:aspC
controlled: 2.6.1.1
control type: ACTIVATION

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/SMPDB SMP0000827
type: UnificationXref
id: SMP0000827
db: SMPDB

Chorismate
type: SmallMolecule
entity reference: Chorismate
name: SubPathwayOutput

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

Oxygen
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001377
xref: Reference/ChemSpider 952
xref: Reference/KEGG Compound C00007
xref: Reference/ChEBI CHEBI 15379
xref: Reference/PubChem-compound 977
xref: Reference/BioCyc CPD-6641
xref: Reference/CAS 7782-44-7
chemical formula: O2
molecular weight: 31.98983
structure: ChemicalStructure/PW C001065

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000159
type: UnificationXref
id: HMDB0000159
db: HMDB

Reference/BioCyc AMMONIA
type: UnificationXref
id: AMMONIA
db: BioCyc

ChemicalStructure/PW C000035
type: ChemicalStructure
structure format: SMILES
structure data: N

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reaction675118
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000131/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Water
right: Phenylpyruvic acid
right: Carbon dioxide
spontaneous: false
left: Prephenate
left: Hydrogen Ion
name: Hydrogen Ion + Prephenate → Carbon dioxide + Phenylpyruvic acid + Water
conversion direction: LEFT_TO_RIGHT

5.4.99.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
right: Prephenate
spontaneous: false
EC number: 5.4.99.5
left: Chorismate
name: Chorismate → Prephenate
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis671060
type: Catalysis
controller: chorismate mutase:pheA
controlled: Reaction675118
control type: ACTIVATION

2.6.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000131/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: Oxoglutaric acid
right: L-Phenylalanine
spontaneous: false
EC number: 2.6.1.1
left: L-Glutamic acid
left: Phenylpyruvic acid
name: L-Glutamic acid + Phenylpyruvic acid → L-Phenylalanine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/CAS 156-06-9
type: UnificationXref
id: 156-06-9
db: CAS

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/SMPDB SMP0000836
type: UnificationXref
id: SMP0000836
db: SMPDB

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChEBI CHEBI 17295
type: UnificationXref
id: CHEBI:17295
db: ChEBI

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/CAS 7782-44-7
type: UnificationXref
id: 7782-44-7
db: CAS

Reference/HMDB HMDB0001377
type: UnificationXref
id: HMDB0001377
db: HMDB

Reference/BioCyc PHE
type: UnificationXref
id: PHE
db: BioCyc

Protein/60931/Stoichiometry/4.0
type: Stoichiometry
physical entity: Starvation-sensing protein RspA
stoichiometric coefficient: 4.0

2.6.1.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000131/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: Oxoglutaric acid
right: Phenylpyruvic acid
spontaneous: false
EC number: 2.6.1.57
left: Oxygen
left: L-Phenylalanine
name: L-Phenylalanine + Oxygen ↔ Oxoglutaric acid + Phenylpyruvic acid
conversion direction: REVERSIBLE

1.11.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001065/Stoichiometry/1.0
participant stoichiometry: Compound/PW C006723/Stoichiometry/1.0
right: 2-Phenylacetamide
right: Carbon dioxide
spontaneous: false
EC number: 1.11.1.21
left: Oxygen
left: L-Phenylalanine
name: L-Phenylalanine + Oxygen ↔ 2-Phenylacetamide + Carbon dioxide
conversion direction: REVERSIBLE

1.4.99.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042923/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000131/Stoichiometry/1.0
participant stoichiometry: Protein/29199/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035/Stoichiometry/1.0
right: Water
right: Unknown
right: D-phenylalanine
spontaneous: false
EC number: 1.4.99.1
left: Unknown
left: Ammonia
left: Phenylpyruvic acid
name: Ammonia + Phenylpyruvic acid + cytochrome c nitrite reductase ↔ D-phenylalanine + Water + cytochrome c nitrite reductase
conversion direction: REVERSIBLE

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

Reference/UniProt S3J0N6
type: UnificationXref
id: S3J0N6
db: UniProt

Unknown
type: Protein
entity reference: Unknown

Reference/CAS 103-81-1
type: UnificationXref
id: 103-81-1
db: CAS

L-Phenylalanine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6140
xref: Reference/HMDB HMDB0000159
xref: Reference/ChemSpider 5910
xref: Reference/ChEBI CHEBI 17295
xref: Reference/BioCyc PHE
xref: Reference/CAS 63-91-2
xref: Reference/KEGG Compound C00079
chemical formula: C9H11NO2
molecular weight: 165.07898
structure: ChemicalStructure/PW C000104

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

TransportCatalysis31533
type: Catalysis
controller: Unknown
controlled: Transport50100
control type: ACTIVATION

Reference/KEGG Compound C00079
type: UnificationXref
id: C00079
db: KEGG Compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Compound/PW C042923/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-phenylalanine
stoichiometric coefficient: 1.0

Reference/ChemSpider 972
type: UnificationXref
id: 972
db: ChemSpider

ChemicalStructure/PW C001065
type: ChemicalStructure
structure format: SMILES
structure data: O=O

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/CAS 126-49-8
type: UnificationXref
id: 126-49-8
db: CAS

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Phenylpyruvic acid
type: SmallMolecule
entity reference: Phenylpyruvic acid

Reference/HMDB HMDB0000051
type: UnificationXref
id: HMDB0000051
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

SubPathwayInteraction446208
type: Interaction
name: SubPathway446208Reaction
name: SubPathwayReaction
participant: L-Phenylalanine

Reference/PathWhiz PW000816
type: UnificationXref
id: PW000816
db: PathWhiz

SubPathwayInteraction446209
type: Interaction
name: SubPathway446209Reaction
name: SubPathwayReaction
participant: Chorismate

Protein/29200/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aminotransferase
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15379
type: UnificationXref
id: CHEBI:15379
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Compound/PW C000104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Phenylalanine
stoichiometric coefficient: 1.0

Reference/ChemSpider 5910
type: UnificationXref
id: 5910
db: ChemSpider

Reference/HMDB HMDB0012283
type: UnificationXref
id: HMDB0012283
db: HMDB

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000807
type: UnificationXref
id: PW000807
db: PathWhiz

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Compound/PW C000104 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Phenylalanine
stoichiometric coefficient: 1.0

Catalase Peroxidase
type: Complex
component stoichiometry: Protein/60931/Stoichiometry/4.0
component: Starvation-sensing protein RspA

Reference/ChEBI CHEBI 30851
type: UnificationXref
id: CHEBI:30851
db: ChEBI

ChemicalStructure/PW C007823
type: ChemicalStructure
structure format: SMILES

Compound/PW C000131/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phenylpyruvic acid
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/PubChem-compound 977
type: UnificationXref
id: 977
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

FAD dependent oxidoreductase
type: ProteinReference
xref: Reference/UniProt S3IV45

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

L-Phenylalanine
type: SmallMolecule
entity reference: L-Phenylalanine
name: SubPathwayInput

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Reference/ChEBI CHEBI 16562
type: UnificationXref
id: CHEBI:16562
db: ChEBI

phenylalanine aminotransferase
type: Complex
component stoichiometry: Protein/29200/Stoichiometry/2.0
component: Aminotransferase

Reference/UniProt S3ITF6
type: UnificationXref
id: S3ITF6
db: UniProt

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Aminotransferase
type: ProteinReference
xref: Reference/UniProt S3J0N6