3-isopropylmalate dehydratase large subunit
cis-Aconitic acid → trans-Aconitic acid
Hydroxypropanedioic acid inhibits isocitrate lyase
Potassium-transporting ATPase KdpC subunit
Acetyl-CoA + Glyoxylic acid + Water → Coenzyme A + Hydrogen Ion + L-Malic acid
Acetyl-CoA + Oxalacetic acid + Water → Citric acid + Coenzyme A + Hydrogen Ion
Citric acid → Water + cis-Aconitic acid
L-Malic acid + NAD → Hydrogen Ion + NADH + Oxalacetic acid
Water + cis-Aconitic acid ↔ Isocitric acid
Isocitric acid ↔ Glyoxylic acid + Succinic acid
Citrate hydro-lyase (cis-aconitate-forming)
Escherichia coli (strain K12 / MC4100 / BW2952)