Bifunctional aspartokinase/homoserine dehydrogenase
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Dihydrodipicolinate synthase family protein
Secondary Metabolites: Threonine Biosynthesis from Aspartate
aspartate kinase / homoserine dehydrogenase
4-hydroxy-tetrahydrodipicolinate synthase
O-Phosphohomoserine + Water → L-Threonine + Phosphate
L-Aspartate-semialdehyde + Pyruvic acid ↔ L-2,3-Dihydrodipicolinate + 2 Water
Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate
Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate
Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP
Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)