3-isopropylmalate dehydratase small subunit
Branched-chain-amino-acid aminotransferase
3-isopropylmalate dehydratase large subunit
Secondary Metabolites: Leucine Biosynthesis
branched-chain amino-acid aminotransferase
D-malate dehydrogenase [decarboxylating]
3-Isopropylmalate + NAD → 2-Isopropyl-3-oxosuccinate + Hydrogen Ion + NADH
Isopropylmaleate + Water → 3-Isopropylmalate
2-Isopropylmalic acid → Isopropylmaleate + Water
Ketoleucine + L-Glutamic acid → L-Leucine + Oxoglutaric acid
2-Isopropyl-3-oxosuccinate + Hydrogen Ion → Carbon dioxide + Ketoleucine
3-Methyl-2-oxovaleric acid + Acetyl-CoA + Water → 2-Isopropylmalic acid + Coenzyme A + Hydrogen Ion