Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C001064/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Keto-3-deoxy-6-phosphogluconic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Compound/PW C043174/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Idonate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PathWhiz PW482637
type: UnificationXref
id: PW482637
db: PathWhiz

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

SubPathway
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway510530
pathway component: SubPathwayInteraction510530

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 49
type: UnificationXref
id: 49
db: ChemSpider

Reference/PubChem-compound 50
type: UnificationXref
id: 50
db: PubChem-compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Compound/PW C043173/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2,5-Diketo-D-gluconate
stoichiometric coefficient: 1.0

Reference/ChemSpider 2338483
type: UnificationXref
id: 2338483
db: ChemSpider

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/PubChem-compound 9548631
type: UnificationXref
id: 9548631
db: PubChem-compound

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/PubChem-compound 439184
type: UnificationXref
id: 439184
db: PubChem-compound

Reference/CAS 3470-36-8
type: UnificationXref
id: 3470-36-8
db: CAS

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/ChemSpider 152
type: UnificationXref
id: 152
db: ChemSpider

Reference/BioCyc 2-KETO-3-DEOXY-6-P-GLUCONATE
type: UnificationXref
id: 2-KETO-3-DEOXY-6-P-GLUCONATE
db: BioCyc

SubPathwayInteraction510530
type: Interaction
name: SubPathway510530Reaction
name: SubPathwayReaction
participant: D-Ribulose 5-phosphate

Reference/BioCyc CPD-645
type: UnificationXref
id: CPD-645
db: BioCyc

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 33198
type: UnificationXref
id: CHEBI:33198
db: ChEBI

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

2-Keto-3-deoxy-6-phosphogluconic acid
type: SmallMolecule
entity reference: 2-Keto-3-deoxy-6-phosphogluconic acid

Bacteroides sp. D1
type: BioSource
xref: Reference/TAXONOMY 556258

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C043030
type: ChemicalStructure
structure format: SMILES

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Protein/28994/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/PubChem-compound 3080745
type: UnificationXref
id: 3080745
db: PubChem-compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C00257
type: UnificationXref
id: C00257
db: KEGG Compound

Reference/ChEBI CHEBI 17363
type: UnificationXref
id: CHEBI:17363
db: ChEBI

1.1.1.79
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007305/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043173/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: 5-Keto-D-gluconate
right: NADP
spontaneous: false
EC number: 1.1.1.79
left: Hydrogen Ion
left: NADPH
left: 2,5-Diketo-D-gluconate
name: 2,5-Diketo-D-gluconate + Hydrogen Ion + NADPH → 5-Keto-D-gluconate + NADP
conversion direction: LEFT_TO_RIGHT

1.1.1.69
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000486/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007305/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Gluconic acid
right: NADP
spontaneous: false
EC number: 1.1.1.69
left: 5-Keto-D-gluconate
left: Hydrogen Ion
left: NADPH
name: 5-Keto-D-gluconate + Hydrogen Ion + NADPH → Gluconic acid + NADP
conversion direction: LEFT_TO_RIGHT

Reaction1197762
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000479/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043030/Stoichiometry/1.0
right: Carbon dioxide
right: D-Ribulose 5-phosphate
right: NADPH
spontaneous: false
left: NADP
left: gluconate 6-phosphate
name: NADP + gluconate 6-phosphate → Carbon dioxide + D-Ribulose 5-phosphate + NADPH
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C007305
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)C(O)C(O)C(O)C(O)=O

4.1.3.16
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: D-Glyceraldehyde 3-phosphate
right: Pyruvic acid
spontaneous: false
EC number: 4.1.3.16
left: 2-Keto-3-deoxy-6-phosphogluconic acid
name: 2-Keto-3-deoxy-6-phosphogluconic acid → D-Glyceraldehyde 3-phosphate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C007306
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)C(O)C(O)C(=O)C(O)=O

4.2.1.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043030/Stoichiometry/1.0
right: Water
right: 2-Keto-3-deoxy-6-phosphogluconic acid
spontaneous: false
EC number: 4.2.1.12
left: gluconate 6-phosphate
name: gluconate 6-phosphate → 2-Keto-3-deoxy-6-phosphogluconic acid + Water
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
entity reference: D-Glyceraldehyde 3-phosphate

2.7.1.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000486/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043030/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: gluconate 6-phosphate
spontaneous: false
EC number: 2.7.1.12
left: Gluconic acid
left: Adenosine triphosphate
name: Adenosine triphosphate + Gluconic acid → Adenosine diphosphate + Hydrogen Ion + gluconate 6-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reaction1197758
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000486/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007306/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Gluconic acid
right: NADP
spontaneous: false
left: 2-Keto-L-gluconate
left: Hydrogen Ion
left: NADPH
name: 2-Keto-L-gluconate + Hydrogen Ion + NADPH → Gluconic acid + NADP
conversion direction: LEFT_TO_RIGHT

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

ChemicalStructure/PW C000479
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)[C@H](O)[C@H](O)COP(O)(O)=O

1.1.1.264
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007305/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: 5-Keto-D-gluconate
right: Hydrogen Ion
right: NADPH
spontaneous: false
EC number: 1.1.1.264
left: NADP
left: L-Idonate
name: L-Idonate + NADP → 5-Keto-D-gluconate + Hydrogen Ion + NADPH
conversion direction: LEFT_TO_RIGHT

Reaction1197754
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007306/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADP
right: L-Idonate
spontaneous: false
left: 2-Keto-L-gluconate
left: Hydrogen Ion
left: NADPH
name: 2-Keto-L-gluconate + Hydrogen Ion + NADPH → L-Idonate + NADP
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc GLUCONATE
type: UnificationXref
id: GLUCONATE
db: BioCyc

1.1.1.274
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007306/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043173/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: 2-Keto-L-gluconate
right: NADP
spontaneous: false
EC number: 1.1.1.274
left: Hydrogen Ion
left: NADPH
left: 2,5-Diketo-D-gluconate
name: 2,5-Diketo-D-gluconate + Hydrogen Ion + NADPH → 2-Keto-L-gluconate + NADP
conversion direction: LEFT_TO_RIGHT

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

6-phosphogluconate dehydrogenase
type: Complex
component stoichiometry: Protein/28994/Stoichiometry/2.0
component: Unknown

Unknown
type: ProteinReference

ChemicalStructure/PW C000486
type: ChemicalStructure
structure format: SMILES

Reference/CAS 4151-19-3
type: UnificationXref
id: 4151-19-3
db: CAS

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

ChemicalStructure/PW C043173
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C043174
type: ChemicalStructure
structure format: SMILES

Ketogluconate Metabolism
type: Pathway
pathway order: PathwayEnzymeReaction/6825928
pathway order: PathwayEnzymeReaction/6825939
pathway order: PathwayEnzymeReaction/6825918
pathway order: PathwayEnzymeReaction/6825908
pathway order: PathwayEnzymeReaction/6825935
pathway order: PathwayEnzymeReaction/6825936
pathway order: PathwayEnzymeReaction/6825937
pathway order: PathwayEnzymeReaction/6825921
pathway order: PathwaySubPathway/510530
pathway order: PathwayEnzymeReaction/6825933
pathway order: PathwayEnzymeReaction/6825934
pathway component: ReactionCatalysis1226439
pathway component: 2.7.1.12
pathway component: Reaction1197758
pathway component: SubPathway
pathway component: 1.1.1.264
pathway component: Reaction1197754
pathway component: 1.1.1.79
pathway component: 1.1.1.69
pathway component: 1.1.1.274
pathway component: ReactionCatalysis1226441
pathway component: Reaction1197762
pathway component: 4.1.3.16
pathway component: 4.2.1.12
pathway component: ReactionCatalysis1226437
pathway component: ReactionCatalysis1226448
pathway component: ReactionCatalysis1226435
pathway component: ReactionCatalysis1226446
pathway component: ReactionCatalysis1226444
pathway component: ReactionCatalysis1226445
pathway component: ReactionCatalysis1226442
pathway component: ReactionCatalysis1226443
xref: Reference/PathWhiz PW482637
xref: Reference/SMPDB SMP0463592
organism: Bacteroides sp. D1

Reference/CAS 91548-32-2
type: UnificationXref
id: 91548-32-2
db: CAS

Compound/PW C007305/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Keto-D-gluconate
stoichiometric coefficient: 1.0

glyoxylate reductase
type: Complex
component stoichiometry: Protein/28994/Stoichiometry/2.0
component: Unknown

Water
type: SmallMolecule
entity reference: Water

Reference/TAXONOMY 556258
type: UnificationXref
id: 556258
db: TAXONOMY

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Reference/CAS 27244-54-8
type: UnificationXref
id: 27244-54-8
db: CAS

L-Idonate
type: SmallMolecule
entity reference: L-Idonate

L-Idonate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17796
xref: Reference/PubChem-compound 604
chemical formula: C6H12O7
molecular weight: 196.0583
structure: ChemicalStructure/PW C043174

2,5-Diketo-D-gluconate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 9548631
xref: Reference/ChEBI CHEBI 11449
chemical formula: C6H7O7
molecular weight: 191.01918
structure: ChemicalStructure/PW C043173

Reference/ChEBI CHEBI 2229
type: UnificationXref
id: CHEBI:2229
db: ChEBI

2,5-Diketo-D-gluconate
type: SmallMolecule
entity reference: 2,5-Diketo-D-gluconate

Protein/28994/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

ReactionCatalysis1226439
type: Catalysis
controller: Unknown
controlled: 1.1.1.264
control type: ACTIVATION

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

ReactionCatalysis1226441
type: Catalysis
controller: 2,3-diketo-L-gulonate reductase
controlled: Reaction1197758
control type: ACTIVATION

2-Keto-3-deoxy-6-phosphogluconic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001376
xref: Reference/CAS 27244-54-8
xref: Reference/PubChem-compound 3080745
xref: Reference/ChEBI CHEBI 15925
xref: Reference/BioCyc 2-KETO-3-DEOXY-6-P-GLUCONATE
xref: Reference/ChemSpider 2338483
xref: Reference/KEGG Compound C04442
chemical formula: C6H11O9P
molecular weight: 258.01407
structure: ChemicalStructure/PW C001064

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Compound/PW C000486/Stoichiometry/1.0
type: Stoichiometry
physical entity: Gluconic acid
stoichiometric coefficient: 1.0

ReactionCatalysis1226448
type: Catalysis
controller: glyoxylate reductase
controlled: 1.1.1.79
control type: ACTIVATION

ReactionCatalysis1226446
type: Catalysis
controller: Unknown
controlled: 1.1.1.69
control type: ACTIVATION

ReactionCatalysis1226444
type: Catalysis
controller: multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase
controlled: 4.1.3.16
control type: ACTIVATION

ReactionCatalysis1226445
type: Catalysis
controller: 6-phosphogluconate dehydrogenase
controlled: Reaction1197762
control type: ACTIVATION

ReactionCatalysis1226442
type: Catalysis
controller: Unknown
controlled: 2.7.1.12
control type: ACTIVATION

ReactionCatalysis1226443
type: Catalysis
controller: Unknown
controlled: 4.2.1.12
control type: ACTIVATION

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/PubChem-compound 10690
type: UnificationXref
id: 10690
db: PubChem-compound

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/HMDB HMDB0011732
type: UnificationXref
id: HMDB0011732
db: HMDB

Reference/HMDB HMDB0011731
type: UnificationXref
id: HMDB0011731
db: HMDB

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/HMDB HMDB0001376
type: UnificationXref
id: HMDB0001376
db: HMDB

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Compound/PW C007306/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Keto-L-gluconate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6602434
type: UnificationXref
id: 6602434
db: PubChem-compound

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

2,3-diketo-L-gulonate reductase
type: Complex
component stoichiometry: Protein/28994/Stoichiometry/2.0
component: Unknown

Reference/PubChem-compound 604
type: UnificationXref
id: 604
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/BioCyc RIBULOSE-5P
type: UnificationXref
id: RIBULOSE-5P
db: BioCyc

Reference/KEGG Compound C00199
type: UnificationXref
id: C00199
db: KEGG Compound

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/KEGG Compound C03342
type: UnificationXref
id: C03342
db: KEGG Compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

ChemicalStructure/PW C001064
type: ChemicalStructure
structure format: SMILES

2-Keto-L-gluconate
type: SmallMoleculeReference
xref: Reference/ChemSpider 49
xref: Reference/PubChem-compound 50
xref: Reference/HMDB HMDB0011732
xref: Reference/CAS 91548-32-2
xref: Reference/KEGG Compound C03342
chemical formula: C6H10O7
molecular weight: 194.04265
structure: ChemicalStructure/PW C007306

5-Keto-D-gluconate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 157
xref: Reference/BioCyc CPD-645
xref: Reference/KEGG Compound C01062
xref: Reference/ChemSpider 152
xref: Reference/HMDB HMDB0011731
xref: Reference/CAS 3470-36-8
chemical formula: C6H10O7
molecular weight: 194.04265
structure: ChemicalStructure/PW C007305

Reference/ChemSpider 10240
type: UnificationXref
id: 10240
db: ChemSpider

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

multifunctional 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase and oxaloacetate decarboxylase
type: Complex
component stoichiometry: Protein/28994/Stoichiometry/4.0
component: Unknown

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 17796
type: UnificationXref
id: CHEBI:17796
db: ChEBI

Reference/PubChem-compound 157
type: UnificationXref
id: 157
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

D-Ribulose 5-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 4151-19-3
xref: Reference/BioCyc RIBULOSE-5P
xref: Reference/KEGG Compound C00199
xref: Reference/PubChem-compound 439184
xref: Reference/HMDB HMDB0000618
xref: Reference/ChEBI CHEBI 17363
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C000479

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/KEGG Compound C04442
type: UnificationXref
id: C04442
db: KEGG Compound

Reference/HMDB HMDB0000618
type: UnificationXref
id: HMDB0000618
db: HMDB

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 11449
type: UnificationXref
id: CHEBI:11449
db: ChEBI

Reference/CAS 526-95-4
type: UnificationXref
id: 526-95-4
db: CAS

Gluconic acid
type: SmallMolecule
entity reference: Gluconic acid

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/KEGG Compound C01062
type: UnificationXref
id: C01062
db: KEGG Compound

ReactionCatalysis1226437
type: Catalysis
controller: glyoxylate reductase
controlled: Reaction1197754
control type: ACTIVATION

Gluconic acid
type: SmallMoleculeReference
xref: Reference/CAS 526-95-4
xref: Reference/PubChem-compound 10690
xref: Reference/HMDB HMDB0000625
xref: Reference/ChemSpider 10240
xref: Reference/KEGG Compound C00257
xref: Reference/ChEBI CHEBI 33198
xref: Reference/BioCyc GLUCONATE
chemical formula: C6H12O7
molecular weight: 196.0583
structure: ChemicalStructure/PW C000486

ReactionCatalysis1226435
type: Catalysis
controller: Unknown
controlled: 1.1.1.274
control type: ACTIVATION

Reference/ChEBI CHEBI 15925
type: UnificationXref
id: CHEBI:15925
db: ChEBI

Compound/PW C000869/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0463592
type: UnificationXref
id: SMP0463592
db: SMPDB

D-Ribulose 5-phosphate
type: SmallMolecule
entity reference: D-Ribulose 5-phosphate
name: SubPathwayInput

Reference/HMDB HMDB0000625
type: UnificationXref
id: HMDB0000625
db: HMDB

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

5-Keto-D-gluconate
type: SmallMolecule
entity reference: 5-Keto-D-gluconate

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

2-Keto-L-gluconate
type: SmallMolecule
entity reference: 2-Keto-L-gluconate

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Compound/PW C000479/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribulose 5-phosphate
stoichiometric coefficient: 1.0

Unknown
type: Protein
entity reference: Unknown

Compound/PW C043030/Stoichiometry/1.0
type: Stoichiometry
physical entity: gluconate 6-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

gluconate 6-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6602434
xref: Reference/ChEBI CHEBI 2229
chemical formula: C6H11O10P
molecular weight: 274.00897
structure: ChemicalStructure/PW C043030

gluconate 6-phosphate
type: SmallMolecule
entity reference: gluconate 6-phosphate