hydrogenase (acceptor)
type: ProteinReference
xref: Reference/UniProt D4F7Q0
organism: Edwardsiella tarda ATCC 23685

Reference/KEGG Compound C02730
type: UnificationXref
id: C02730
db: KEGG Compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

hydrogenase
type: Complex
cellular location: Cytosol
component: hydrogenase (acceptor)
component: Ni/Fe-hydrogenase, b-type cytochrome subunit

AMP-binding enzyme
type: Protein
entity reference: AMP-binding enzyme

Enoyl-CoA hydratase/isomerase family protein
type: Protein
entity reference: Enoyl-CoA hydratase/isomerase family protein

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/PubChem-compound 58838673
type: UnificationXref
id: 58838673
db: PubChem-compound

isochorismate
type: SmallMolecule
entity reference: isochorismate

2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
type: SmallMolecule
entity reference: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
type: SmallMolecule
entity reference: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

Reference/ChEBI CHEBI 18325
type: UnificationXref
id: CHEBI:18325
db: ChEBI

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

ReactionCatalysis505878
type: Catalysis
controller: Isochorismate synthase MenF
controlled: 5.4.4.2
control type: ACTIVATION

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

2-succinylbenzoate
type: SmallMolecule
entity reference: 2-succinylbenzoate

1,4-dihydroxy-2-naphthoyl-CoA
type: SmallMolecule
entity reference: 1,4-dihydroxy-2-naphthoyl-CoA

1,4-dihydroxy-2-naphthoate
type: SmallMolecule
entity reference: 1,4-dihydroxy-2-naphthoate

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

Acetolactate synthase
type: Protein
entity reference: Acetolactate synthase

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Reference/KEGG Compound C03160
type: UnificationXref
id: C03160
db: KEGG Compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/PubChem-compound 45479636
type: UnificationXref
id: 45479636
db: PubChem-compound

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Protein/29708/Stoichiometry/6.0
type: Stoichiometry
physical entity: Enoyl-CoA hydratase/isomerase family protein
stoichiometric coefficient: 6.0

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

isochorismate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 29780
xref: Reference/KEGG Compound C00885
chemical formula: C10H8O6
molecular weight: 224.03319
structure: ChemicalStructure/PW C040741

2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 50271
xref: Reference/KEGG Compound C16519
xref: Reference/PubChem-compound 51090848
chemical formula: C14H16O9
molecular weight: 328.07944
structure: ChemicalStructure/PW C040742

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05817
xref: Reference/ChEBI CHEBI 58689
chemical formula: C11H10O6
molecular weight: 238.04883
structure: ChemicalStructure/PW C040743

Compound/PW C043020 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Farnesylfarnesylgeranyl-PP
stoichiometric coefficient: 1.0

2-succinylbenzoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18325
xref: Reference/KEGG Compound C02730
chemical formula: C11H8O5
molecular weight: 220.03827
structure: ChemicalStructure/PW C040744

1,4-dihydroxy-2-naphthoyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C15547
xref: Reference/ChEBI CHEBI 58897
chemical formula: C32H38N7O19P3S
molecular weight: 949.1178
structure: ChemicalStructure/PW C040746

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

1,4-dihydroxy-2-naphthoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 11173
xref: Reference/KEGG Compound C03657
chemical formula: C32H38N7O19P3S
molecular weight: 949.1178
structure: ChemicalStructure/PW C040747

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChemSpider 4444251
type: UnificationXref
id: 4444251
db: ChemSpider

Protein/61670/Stoichiometry/2.0
type: Stoichiometry
physical entity: Acetolactate synthase
stoichiometric coefficient: 2.0

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/UniProt D4F1X4
type: UnificationXref
id: D4F1X4
db: UniProt

Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
type: UnificationXref
id: ALPHA-GLUCOSE-16-BISPHOSPHATE
db: BioCyc

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Adenosine monophosphate
type: SmallMolecule
entity reference: Adenosine monophosphate

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/PubChem-compound 5376004
type: UnificationXref
id: 5376004
db: PubChem-compound

Reference/ChEBI CHEBI 61873
type: UnificationXref
id: CHEBI:61873
db: ChEBI

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Menaquinol Biosythesis
type: Pathway
pathway order: PathwayEnzymeReaction/6858491
pathway order: PathwayEnzymeReaction/6858481
pathway order: PathwayEnzymeReaction/6858492
pathway order: PathwayEnzymeReaction/6858493
pathway order: PathwayEnzymeReaction/6858494
pathway order: PathwayEnzymeReaction/6858474
pathway order: PathwayEnzymeReaction/6858485
pathway order: PathwayEnzymeReaction/6858487
pathway order: PathwayEnzymeReaction/6858455
pathway order: PathwaySubPathway/513426
pathway order: PathwayEnzymeReaction/6858468
pathway order: PathwayEnzymeReaction/6858458
pathway component: ReactionCatalysis1244767
pathway component: 5.4.4.2
pathway component: ReactionCatalysis1244755
pathway component: 6.2.1.26
pathway component: 3.1.2.28
pathway component: Endocytosis
pathway component: Reaction1215366
pathway component: 2.2.1.9
pathway component: 4.1.3.36
pathway component: ReactionCatalysis1244769
pathway component: ReactionCatalysis1244759
pathway component: ReactionCatalysis505878
pathway component: 4.2.1.113
pathway component: 1.12.99.6
pathway component: 4.2.99.20
pathway component: 2.1.1.163
pathway component: 2.5.1.74
pathway component: ReactionCatalysis1244770
pathway component: ReactionCatalysis1244771
pathway component: ReactionCatalysis1244764
pathway component: ReactionCatalysis1244772
pathway component: ReactionCatalysis1244762
pathway component: ReactionCatalysis1244773
xref: Reference/SMPDB SMP0466350
xref: Reference/PathWhiz PW485818
organism: Edwardsiella tarda ATCC 23685

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Pyrophosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyrophosphate

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Reference/KEGG Compound C04146
type: UnificationXref
id: C04146
db: KEGG Compound

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/HMDB HMDB0001094
type: UnificationXref
id: HMDB0001094
db: HMDB

Reference/ChEBI CHEBI 29780
type: UnificationXref
id: CHEBI:29780
db: ChEBI

ChemicalStructure/PW C041590
type: ChemicalStructure
structure format: SMILES

Compound/PW C000032/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/UniProt D4F5F2
type: UnificationXref
id: D4F5F2
db: UniProt

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

Carbon dioxide
type: SmallMolecule
cellular location: Cytosol
entity reference: Carbon dioxide

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Compound/PW C000170 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 58897
type: UnificationXref
id: CHEBI:58897
db: ChEBI

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Compound/PW C041546/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Demethylmenaquinol 8
stoichiometric coefficient: 1.0

Compound/PW C001051 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen
stoichiometric coefficient: 1.0

Acetolactate synthase
type: ProteinReference
xref: Reference/UniProt D4F243

ChemicalStructure/PW C043020
type: ChemicalStructure
structure format: SMILES
structure data: [H]\C(CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])CC\C(C)=C(/[H])COP([O-])(=O)OP([O-])([O-])=O)=C(\C)CCC=C(C)C

Reference/ChEBI CHEBI 11173
type: UnificationXref
id: CHEBI:11173
db: ChEBI

Unknown
type: Protein
entity reference: Unknown

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

2.2.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040741/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040742/Stoichiometry/1.0
right: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
right: Carbon dioxide
spontaneous: false
EC number: 2.2.1.9
left: isochorismate
left: Oxoglutaric acid
left: Hydrogen Ion
name: Hydrogen Ion + Oxoglutaric acid + isochorismate → 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C05817
type: UnificationXref
id: C05817
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

SubPathwayInteraction513426
type: Interaction
name: SubPathwayReaction
name: SubPathway513426Reaction
participant: Chorismate

4.2.1.113
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040744/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040743/Stoichiometry/1.0
right: Water
right: 2-succinylbenzoate
spontaneous: false
EC number: 4.2.1.113
left: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
name: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate → 2-succinylbenzoate + Water
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

4.2.99.20
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040743/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040742/Stoichiometry/1.0
right: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
right: Pyruvic acid
spontaneous: false
EC number: 4.2.99.20
left: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
name: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate → (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

hydrogenase (acceptor)
type: Protein
cellular location: Cytosol
entity reference: hydrogenase (acceptor)

Enoyl-CoA hydratase/isomerase family protein
type: ProteinReference
xref: Reference/UniProt D4F8P2

Reference/PubChem-compound 126279
type: UnificationXref
id: 126279
db: PubChem-compound

Protein/86588/Stoichiometry/4.0
type: Stoichiometry
physical entity: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase
stoichiometric coefficient: 4.0

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Hydrogen
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen

Menaquinol 8
type: SmallMolecule
entity reference: Menaquinol 8

Menaquinol 8
type: SmallMoleculeReference
xref: Reference/PubChem-compound 45479636
xref: Reference/ChEBI CHEBI 61684
chemical formula: C51H74O2
molecular weight: 718.5689
structure: ChemicalStructure/PW C041590

Reference/PubChem-compound 45479277
type: UnificationXref
id: 45479277
db: PubChem-compound

Compound/PW C041546 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Demethylmenaquinol 8
stoichiometric coefficient: 1.0

Hydrogen
type: SmallMoleculeReference
xref: Reference/PubChem-compound 58838673
xref: Reference/CAS 1333-74-0
xref: Reference/ChemSpider 762
xref: Reference/BioCyc ALPHA-GLUCOSE-16-BISPHOSPHATE
xref: Reference/KEGG Compound C00282
xref: Reference/HMDB HMDB0001362
xref: Reference/ChEBI CHEBI 18276
chemical formula: H2
molecular weight: 2.01565
structure: ChemicalStructure/PW C001051

Reference/TAXONOMY 500638
type: UnificationXref
id: 500638
db: TAXONOMY

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C040747/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1,4-dihydroxy-2-naphthoate
stoichiometric coefficient: 1.0

AMP-binding enzyme
type: ProteinReference
xref: Reference/UniProt D4F8N9

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

Reference/ChEBI CHEBI 16275
type: UnificationXref
id: CHEBI:16275
db: ChEBI

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/ChEBI CHEBI 50271
type: UnificationXref
id: CHEBI:50271
db: ChEBI

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

ChemicalStructure/PW C041546
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

S-Adenosylhomocysteine
type: SmallMolecule
entity reference: S-Adenosylhomocysteine

ChemicalStructure/PW C041547
type: ChemicalStructure
structure format: SMILES

Reference/SMPDB SMP0466350
type: UnificationXref
id: SMP0466350
db: SMPDB

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

Protein/34191/Stoichiometry/4.0
type: Stoichiometry
physical entity: AMP-binding enzyme
stoichiometric coefficient: 4.0

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Reference/KEGG Compound C03657
type: UnificationXref
id: C03657
db: KEGG Compound

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/ChEBI CHEBI 58689
type: UnificationXref
id: CHEBI:58689
db: ChEBI

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Octaprenyl diphosphate
type: SmallMolecule
entity reference: Octaprenyl diphosphate

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C043298
type: ChemicalStructure
structure format: SMILES

Octaprenyl diphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5280651
xref: Reference/HMDB HMDB0001094
xref: Reference/BioCyc OCTAPRENYL-DIPHOSPHATE
xref: Reference/KEGG Compound C04146
xref: Reference/ChEBI CHEBI 16275
xref: Reference/ChemSpider 4444251
chemical formula: C40H68O7P2
molecular weight: 722.44403
structure: ChemicalStructure/PW C000860

Reference/ChEBI CHEBI 15509
type: UnificationXref
id: CHEBI:15509
db: ChEBI

ChemicalStructure/PW C040741
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@]1(O)C(=CC=C[C@]1([H])OC(=C)C([O-])=O)C([O-])=O

Compound/PW C040744/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-succinylbenzoate
stoichiometric coefficient: 1.0

Compound/PW C041547 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Demethylmenaquinone 8
stoichiometric coefficient: 1.0

Reference/UniProt D4F8P2
type: UnificationXref
id: D4F8P2
db: UniProt

ChemicalStructure/PW C040744
type: ChemicalStructure
structure format: SMILES
structure data: [O-]C(=O)CCC(=O)C1=CC=CC=C1C([O-])=O

ChemicalStructure/PW C040743
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@]1(O)C=CC=C(C(=O)CCC([O-])=O)[C@@]1([H])C([O-])=O

ChemicalStructure/PW C040742
type: ChemicalStructure
structure format: SMILES

Reference/UniProt D4F7N8
type: UnificationXref
id: D4F7N8
db: UniProt

ChemicalStructure/PW C040747
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C040746
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 18276
type: UnificationXref
id: CHEBI:18276
db: ChEBI

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Reference/KEGG Compound C00282
type: UnificationXref
id: C00282
db: KEGG Compound

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
type: Protein
entity reference: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase

1,4-dihydroxy-2-naphthoyl-CoA hydrolase
type: Protein
entity reference: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase

o-succinylbenzoate synthase
type: Protein
entity reference: o-succinylbenzoate synthase

Isochorismate synthase MenF
type: ProteinReference
xref: Reference/UniProt D4F7P2

1,4-dihydroxy-2-naphthoate octaprenyltransferase
type: Protein
entity reference: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Ni/Fe-hydrogenase, b-type cytochrome subunit
type: ProteinReference
xref: Reference/UniProt D4F1X4
organism: Edwardsiella tarda ATCC 23685

Reference/ChemSpider 10128120
type: UnificationXref
id: 10128120
db: ChemSpider

hydrogenase (acceptor)
type: ProteinReference
xref: Reference/UniProt D4F7P7
organism: Edwardsiella tarda ATCC 23685

Reference/BioCyc CPD-6972
type: UnificationXref
id: CPD-6972
db: BioCyc

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

2-Demethylmenaquinol 8
type: SmallMoleculeReference
xref: Reference/PubChem-compound 45479277
xref: Reference/ChEBI CHEBI 61873
chemical formula: C50H72O2
molecular weight: 704.5532
structure: ChemicalStructure/PW C041546

2-Demethylmenaquinone 8
type: SmallMoleculeReference
xref: Reference/PubChem-compound 5376004
xref: Reference/ChEBI CHEBI 48455
chemical formula: C50H70O2
molecular weight: 702.5376
structure: ChemicalStructure/PW C041547

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 762
type: UnificationXref
id: 762
db: ChemSpider

ChemicalStructure/PW C000860
type: ChemicalStructure
structure format: SMILES

Unknown
type: ProteinReference

Reference/UniProt D4F243
type: UnificationXref
id: D4F243
db: UniProt

2-Succinylbenzoyl-CoA
type: SmallMolecule
entity reference: 2-Succinylbenzoyl-CoA

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

2-Succinylbenzoyl-CoA
type: SmallMoleculeReference
xref: Reference/ChemSpider 10128120
xref: Reference/BioCyc CPD-6972
xref: Reference/KEGG Compound C03160
xref: Reference/PubChem-compound 126279
xref: Reference/ChEBI CHEBI 15509
chemical formula: C32H44N7O20P3S
molecular weight: 971.1575
structure: ChemicalStructure/PW C043298

6.2.1.26
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040744/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043298/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
right: Adenosine monophosphate
right: 2-Succinylbenzoyl-CoA
right: Pyrophosphate
spontaneous: false
EC number: 6.2.1.26
left: Coenzyme A
left: 2-succinylbenzoate
left: Adenosine triphosphate
name: 2-succinylbenzoate + Adenosine triphosphate + Coenzyme A → 2-Succinylbenzoyl-CoA + Adenosine monophosphate + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

3.1.2.28
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040746/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040747/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Coenzyme A
right: Hydrogen Ion
right: 1,4-dihydroxy-2-naphthoate
spontaneous: false
EC number: 3.1.2.28
left: Water
left: 1,4-dihydroxy-2-naphthoyl-CoA
name: 1,4-dihydroxy-2-naphthoyl-CoA + Water → 1,4-dihydroxy-2-naphthoate + Coenzyme A + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reaction1215366
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000860/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040747/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041546/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: 2-Demethylmenaquinol 8
right: Carbon dioxide
right: Pyrophosphate
spontaneous: false
left: Octaprenyl diphosphate
left: Hydrogen Ion
left: 1,4-dihydroxy-2-naphthoate
name: 1,4-dihydroxy-2-naphthoate + Hydrogen Ion + Octaprenyl diphosphate → 2-Demethylmenaquinol 8 + Carbon dioxide + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

4.1.3.36
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043298/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040746/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Water
right: 1,4-dihydroxy-2-naphthoyl-CoA
spontaneous: false
EC number: 4.1.3.36
left: Hydrogen Ion
left: 2-Succinylbenzoyl-CoA
name: 2-Succinylbenzoyl-CoA + Hydrogen Ion → 1,4-dihydroxy-2-naphthoyl-CoA + Water
conversion direction: LEFT_TO_RIGHT

1,4-dihydroxy-2-naphthoate octaprenyltransferase
type: Protein
cellular location: Cytosol
entity reference: 1,4-dihydroxy-2-naphthoate octaprenyltransferase

1.12.99.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041547 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001051 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041546 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: 2-Demethylmenaquinone 8
spontaneous: false
EC number: 1.12.99.6
left: Hydrogen Ion
left: Hydrogen
left: 2-Demethylmenaquinol 8
name: 2-Demethylmenaquinol 8 + Hydrogen + Hydrogen Ion ? 2-Demethylmenaquinone 8 + Hydrogen Ion

Reference/UniProt D4F8N9
type: UnificationXref
id: D4F8N9
db: UniProt

2.1.1.163
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041590/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041546/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: S-Adenosylhomocysteine
right: Hydrogen Ion
right: Menaquinol 8
spontaneous: false
EC number: 2.1.1.163
left: 2-Demethylmenaquinol 8
left: S-Adenosylmethionine
name: 2-Demethylmenaquinol 8 + S-Adenosylmethionine → Hydrogen Ion + Menaquinol 8 + S-Adenosylhomocysteine
conversion direction: LEFT_TO_RIGHT

2.5.1.74
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040747 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043020 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041546 Cytosol/Stoichiometry/1.0
right: Pyrophosphate
right: 2-Demethylmenaquinol 8
right: Carbon dioxide
spontaneous: false
EC number: 2.5.1.74
left: 1,4-dihydroxy-2-naphthoate
left: Farnesylfarnesylgeranyl-PP
left: Hydrogen Ion
name: 1,4-dihydroxy-2-naphthoate + Farnesylfarnesylgeranyl-PP + Hydrogen Ion → 2-Demethylmenaquinol 8 + Carbon dioxide + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C040741/Stoichiometry/1.0
type: Stoichiometry
physical entity: isochorismate
stoichiometric coefficient: 1.0

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Chorismate
type: SmallMolecule
entity reference: Chorismate
name: SubPathwayOutput

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C040746/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1,4-dihydroxy-2-naphthoyl-CoA
stoichiometric coefficient: 1.0

Reference/KEGG Compound C16519
type: UnificationXref
id: C16519
db: KEGG Compound

Reference/HMDB HMDB0001362
type: UnificationXref
id: HMDB0001362
db: HMDB

Reference/KEGG Compound C15547
type: UnificationXref
id: C15547
db: KEGG Compound

1,4-dihydroxy-2-naphthoyl-CoA hydrolase
type: ProteinReference
xref: Reference/UniProt D4F5F2

1,4-dihydroxy-2-naphthoate octaprenyltransferase
type: ProteinReference
xref: Reference/UniProt D4FAP9

Isochorismate synthase MenF
type: Protein
entity reference: Isochorismate synthase MenF

5.4.4.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040741/Stoichiometry/1.0
right: isochorismate
spontaneous: false
EC number: 5.4.4.2
left: Chorismate
name: Chorismate → isochorismate
conversion direction: LEFT_TO_RIGHT

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
type: ProteinReference
xref: Reference/UniProt D4F7P0

o-succinylbenzoate synthase
type: ProteinReference
xref: Reference/UniProt D4F7N8

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C040743/Stoichiometry/1.0
type: Stoichiometry
physical entity: (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Compound/PW C043298/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Succinylbenzoyl-CoA
stoichiometric coefficient: 1.0

Reference/UniProt D4FAP9
type: UnificationXref
id: D4FAP9
db: UniProt

Reference/PubChem-compound 5280651
type: UnificationXref
id: 5280651
db: PubChem-compound

Compound/PW C000860/Stoichiometry/1.0
type: Stoichiometry
physical entity: Octaprenyl diphosphate
stoichiometric coefficient: 1.0

2-Demethylmenaquinol 8
type: SmallMolecule
cellular location: Cytosol
entity reference: 2-Demethylmenaquinol 8

Reference/PubChem-compound 51090848
type: UnificationXref
id: 51090848
db: PubChem-compound

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

ReactionCatalysis1244767
type: Catalysis
controller: 1,4-dihydroxy-2-naphthoyl-CoA synthase
controlled: 4.1.3.36
control type: ACTIVATION

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Reference/CAS 1333-74-0
type: UnificationXref
id: 1333-74-0
db: CAS

Reference/PathWhiz PW485818
type: UnificationXref
id: PW485818
db: PathWhiz

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

ReactionCatalysis1244769
type: Catalysis
controller: 1,4-dihydroxy-2-naphthoyl-CoA thioesterase
controlled: 3.1.2.28
control type: ACTIVATION

1,4-dihydroxy-2-naphthoyl-CoA thioesterase
type: Complex
component stoichiometry: Protein/86588/Stoichiometry/4.0
component: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Edwardsiella tarda ATCC 23685
type: BioSource
xref: Reference/TAXONOMY 500638

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

1,4-dihydroxy-2-naphthoyl-CoA synthase
type: Complex
component stoichiometry: Protein/29708/Stoichiometry/6.0
component: Enoyl-CoA hydratase/isomerase family protein

o-succinylbenzoate-CoA ligase
type: Complex
component stoichiometry: Protein/34191/Stoichiometry/4.0
component: AMP-binding enzyme

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
type: Complex
component stoichiometry: Protein/61670/Stoichiometry/2.0
component: Acetolactate synthase

Compound/PW C040747 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 1,4-dihydroxy-2-naphthoate
stoichiometric coefficient: 1.0

ReactionCatalysis1244770
type: Catalysis
controller: 1,4-dihydroxy-2-naphthoate octaprenyltransferase
controlled: Reaction1215366
control type: ACTIVATION

ReactionCatalysis1244771
type: Catalysis
controller: Unknown
controlled: 2.1.1.163
control type: ACTIVATION

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ReactionCatalysis1244772
type: Catalysis
controller: 1,4-dihydroxy-2-naphthoate octaprenyltransferase
controlled: 2.5.1.74
control type: ACTIVATION

ReactionCatalysis1244773
type: Catalysis
controller: hydrogenase
controlled: 1.12.99.6
control type: ACTIVATION

Reference/ChEBI CHEBI 48455
type: UnificationXref
id: CHEBI:48455
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

ReactionCatalysis1244755
type: Catalysis
controller: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase
controlled: 2.2.1.9
control type: ACTIVATION

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

ReactionCatalysis1244759
type: Catalysis
controller: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
controlled: 4.2.99.20
control type: ACTIVATION

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

2-Demethylmenaquinone 8
type: SmallMolecule
cellular location: Cytosol
entity reference: 2-Demethylmenaquinone 8

Reference/KEGG Compound C00885
type: UnificationXref
id: C00885
db: KEGG Compound

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

ReactionCatalysis1244764
type: Catalysis
controller: o-succinylbenzoate-CoA ligase
controlled: 6.2.1.26
control type: ACTIVATION

ReactionCatalysis1244762
type: Catalysis
controller: o-succinylbenzoate synthase
controlled: 4.2.1.113
control type: ACTIVATION

Reference/UniProt D4F7P2
type: UnificationXref
id: D4F7P2
db: UniProt

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

2-Demethylmenaquinol 8
type: SmallMolecule
entity reference: 2-Demethylmenaquinol 8

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Reference/UniProt D4F7P7
type: UnificationXref
id: D4F7P7
db: UniProt

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Compound/PW C000749/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Farnesylfarnesylgeranyl-PP
type: SmallMoleculeReference
chemical formula: C40H65O7P2
molecular weight: 719.42053
structure: ChemicalStructure/PW C043020

Reference/UniProt D4F7P0
type: UnificationXref
id: D4F7P0
db: UniProt

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Compound/PW C041590/Stoichiometry/1.0
type: Stoichiometry
physical entity: Menaquinol 8
stoichiometric coefficient: 1.0

Farnesylfarnesylgeranyl-PP
type: SmallMolecule
cellular location: Cytosol
entity reference: Farnesylfarnesylgeranyl-PP

Endocytosis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway513426
pathway component: SubPathwayInteraction513426
name: SubPathway

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C001316 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Ni/Fe-hydrogenase, b-type cytochrome subunit
type: Protein
cellular location: Cytosol
entity reference: Ni/Fe-hydrogenase, b-type cytochrome subunit

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

1,4-dihydroxy-2-naphthoate
type: SmallMolecule
cellular location: Cytosol
entity reference: 1,4-dihydroxy-2-naphthoate

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

hydrogenase (acceptor)
type: Protein
cellular location: Cytosol
entity reference: hydrogenase (acceptor)

Reference/BioCyc OCTAPRENYL-DIPHOSPHATE
type: UnificationXref
id: OCTAPRENYL-DIPHOSPHATE
db: BioCyc

ChemicalStructure/PW C001051
type: ChemicalStructure
structure format: SMILES
structure data: [H][H]

Compound/PW C040742/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 61684
type: UnificationXref
id: CHEBI:61684
db: ChEBI

Reference/UniProt D4F7Q0
type: UnificationXref
id: D4F7Q0
db: UniProt