Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/CAS 66-22-8
type: UnificationXref
id: 66-22-8
db: CAS

Reference/CAS 365-07-1
type: UnificationXref
id: 365-07-1
db: CAS

Reference/KEGG Compound C00672
type: UnificationXref
id: C00672
db: KEGG Compound

Reference/PubChem-compound 1135
type: UnificationXref
id: 1135
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/CAS 964-26-1
type: UnificationXref
id: 964-26-1
db: CAS

ChemicalStructure/PW C000204
type: ChemicalStructure
structure format: SMILES
structure data: O=C1NC=CC(=O)N1

Compound/PW C000179/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymine
stoichiometric coefficient: 1.0

Thymine
type: SmallMolecule
entity reference: Thymine

Compound/PW C000008 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxycytidine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

5-Thymidylic acid
type: SmallMoleculeReference
xref: Reference/BioCyc TMP
xref: Reference/PubChem-compound 9700
xref: Reference/HMDB HMDB0001227
xref: Reference/ChemSpider 9319
xref: Reference/CAS 365-07-1
xref: Reference/KEGG Compound C00364
xref: Reference/ChEBI CHEBI 17013
chemical formula: C10H15N2O8P
molecular weight: 322.0566
structure: ChemicalStructure/PW C000950

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000300
type: UnificationXref
id: HMDB0000300
db: HMDB

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

ReactionCatalysis1319471
type: Catalysis
controller: Thymidine kinase
controlled: 2.7.1.21
control type: ACTIVATION

Reference/ChEBI CHEBI 17568
type: UnificationXref
id: CHEBI:17568
db: ChEBI

Deoxycytidine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15698
xref: Reference/HMDB HMDB0000014
xref: Reference/CAS 951-77-9
xref: Reference/KEGG Compound C00881
xref: Reference/PubChem-compound 13711
xref: Reference/ChemSpider 13117
xref: Reference/BioCyc DEOXYCYTIDINE
chemical formula: C9H13N3O4
molecular weight: 227.0906
structure: ChemicalStructure/PW C000008

Deoxyuridine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00526
xref: Reference/HMDB HMDB0000012
xref: Reference/BioCyc DEOXYURIDINE
xref: Reference/PubChem-compound 13712
xref: Reference/ChemSpider 13118
xref: Reference/ChEBI CHEBI 16450
xref: Reference/CAS 951-78-0
chemical formula: C9H12N2O5
molecular weight: 228.07462
structure: ChemicalStructure/PW C000007

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

5-Thymidylic acid
type: SmallMolecule
entity reference: 5-Thymidylic acid

Compound/PW C000007/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C00214
type: UnificationXref
id: C00214
db: KEGG Compound

Reference/ChemSpider 1141
type: UnificationXref
id: 1141
db: ChemSpider

Plesiomonas shigelloides 302-73
type: BioSource
xref: Reference/TAXONOMY 1315976

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ChemicalStructure/PW C001087
type: ChemicalStructure
structure format: SMILES

Reference/UniProt R8ALX6
type: UnificationXref
id: R8ALX6
db: UniProt

Compound/PW C001042/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyribose 1-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc DUMP
type: UnificationXref
id: DUMP
db: BioCyc

ReactionCatalysis1319474
type: Catalysis
controller: Thymidine kinase
controlled: Reaction1287623
control type: ACTIVATION

ReactionCatalysis1319475
type: Catalysis
controller: cytidine deaminase
controlled: Reaction1287624
control type: ACTIVATION

Deoxyuridine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Deoxyuridine

ReactionCatalysis1319472
type: Catalysis
controller: thymidine phosphorylase / uracil phosphorylase
controlled: 2.4.2.4
control type: ACTIVATION

ReactionCatalysis1319473
type: Catalysis
controller: thymidine phosphorylase / uracil phosphorylase
controlled: Reaction1287622
control type: ACTIVATION

Reference/KEGG Compound C00106
type: UnificationXref
id: C00106
db: KEGG Compound

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/HMDB HMDB0001409
type: UnificationXref
id: HMDB0001409
db: HMDB

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/PubChem-compound 439287
type: UnificationXref
id: 439287
db: PubChem-compound

cytidine deaminase
type: Complex
component stoichiometry: Protein/91298 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Cytidine deaminase

Reference/BioCyc THYMIDINE
type: UnificationXref
id: THYMIDINE
db: BioCyc

Reference/ChEBI CHEBI 17821
type: UnificationXref
id: CHEBI:17821
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

ChemicalStructure/PW C000008
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000007
type: ChemicalStructure
structure format: SMILES

Compound/PW C000187/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine
stoichiometric coefficient: 1.0

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Deoxyribose 1-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 439287
xref: Reference/KEGG Compound C00672
xref: Reference/CAS 17210-42-3
xref: Reference/BioCyc DEOXY-RIBOSE-1P
xref: Reference/HMDB HMDB0001351
xref: Reference/ChemSpider 388420
xref: Reference/ChEBI CHEBI 28542
chemical formula: C5H11O7P
molecular weight: 214.02425
structure: ChemicalStructure/PW C001042

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Compound/PW C000007 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine
stoichiometric coefficient: 1.0

Reference/ChemSpider 13118
type: UnificationXref
id: 13118
db: ChemSpider

TransportCatalysis58181
type: Catalysis
controller: Nucleoside permease
controlled: Transport78544
control type: ACTIVATION

Reference/ChemSpider 13117
type: UnificationXref
id: 13117
db: ChemSpider

TransportCatalysis58180
type: Catalysis
controller: 3-phenylpropionic acid transporter
controlled: Transport78543
control type: ACTIVATION

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

thymidine phosphorylase / uracil phosphorylase
type: Complex
component stoichiometry: Protein/91297/Stoichiometry/2.0
component: Octaprenyl diphosphate synthase

Reference/CAS 50-89-5
type: UnificationXref
id: 50-89-5
db: CAS

Reference/ChemSpider 9319
type: UnificationXref
id: 9319
db: ChemSpider

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00364
type: UnificationXref
id: C00364
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Protein/91297/Stoichiometry/2.0
type: Stoichiometry
physical entity: Octaprenyl diphosphate synthase
stoichiometric coefficient: 2.0

Reference/BioCyc DEOXY-RIBOSE-1P
type: UnificationXref
id: DEOXY-RIBOSE-1P
db: BioCyc

Protein/91298 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Cytidine deaminase
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/KEGG Compound C00365
type: UnificationXref
id: C00365
db: KEGG Compound

Salvage Pathways of Pyrimidine Deoxyribonucleotides
type: Pathway
pathway order: PathwayEnzymeReaction/7006692
pathway order: PathwayEnzymeReaction/7006696
pathway order: PathwayEnzymeReaction/7006697
pathway order: PathwayEnzymeReaction/7006698
pathway order: PathwayTransport/7006704
pathway order: PathwayTransport/7006705
pathway order: PathwayTransport/7006702
pathway order: PathwayEnzymeReaction/7006701
pathway order: PathwayTransport/7006703
pathway component: ReactionCatalysis1319471
pathway component: Transport78543
pathway component: Transport78544
pathway component: 2.7.1.21
pathway component: Reaction1287622
pathway component: 2.4.2.4
pathway component: Reaction1287624
pathway component: TransportCatalysis58178
pathway component: Reaction1287623
pathway component: TransportCatalysis58179
pathway component: Transport78541
pathway component: Transport78542
pathway component: ReactionCatalysis1319474
pathway component: TransportCatalysis58181
pathway component: ReactionCatalysis1319475
pathway component: ReactionCatalysis1319472
pathway component: ReactionCatalysis1319473
pathway component: TransportCatalysis58180
xref: Reference/SMPDB SMP0479511
xref: Reference/PathWhiz PW501506
organism: Plesiomonas shigelloides 302-73

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Deoxyribose 1-phosphate
type: SmallMolecule
entity reference: Deoxyribose 1-phosphate

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Thymine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17821
xref: Reference/ChemSpider 1103
xref: Reference/CAS 65-71-4
xref: Reference/PubChem-compound 1135
xref: Reference/HMDB HMDB0000262
xref: Reference/BioCyc THYMINE
xref: Reference/KEGG Compound C00178
chemical formula: C5H6N2O2
molecular weight: 126.04293
structure: ChemicalStructure/PW C000179

3-phenylpropionic acid transporter
type: ProteinReference
xref: Reference/UniProt R8ALX6

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Transport78543
type: Transport
participant stoichiometry: Compound/PW C000008 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000008 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Deoxycytidine
spontaneous: false
left: Deoxycytidine
left: Hydrogen Ion
name: Deoxycytidine (→), Hydrogen Ion (→) Transport: Plesiomonas shigelloides 302-73, Periplasmic Space to Plesiomonas shigelloides 302-73, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport78544
type: Transport
participant stoichiometry: Compound/PW C000008 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000008 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Deoxycytidine
spontaneous: false
left: Deoxycytidine
left: Hydrogen Ion
name: Deoxycytidine (→), Hydrogen Ion (→) Transport: Plesiomonas shigelloides 302-73, Periplasmic Space to Plesiomonas shigelloides 302-73, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 58574
type: UnificationXref
id: 58574
db: ChemSpider

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Cytidine deaminase
type: ProteinReference
xref: Reference/UniProt R8AVS1
organism: Plesiomonas shigelloides 302-73

Thymidine kinase
type: ProteinReference
xref: Reference/UniProt R8ANS3

Reference/ChemSpider 388420
type: UnificationXref
id: 388420
db: ChemSpider

Reference/ChEBI CHEBI 17013
type: UnificationXref
id: CHEBI:17013
db: ChEBI

Octaprenyl diphosphate synthase
type: ProteinReference
xref: Reference/UniProt R8AM52

Nucleoside permease
type: ProteinReference
xref: Reference/UniProt R8ATU1

Reference/TAXONOMY 1315976
type: UnificationXref
id: 1315976
db: TAXONOMY

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

TransportCatalysis58178
type: Catalysis
controller: Nucleoside permease
controlled: Transport78541
control type: ACTIVATION

TransportCatalysis58179
type: Catalysis
controller: 3-phenylpropionic acid transporter
controlled: Transport78542
control type: ACTIVATION

Thymidine
type: SmallMolecule
entity reference: Thymidine

Reference/PathWhiz PW501506
type: UnificationXref
id: PW501506
db: PathWhiz

Transport78541
type: Transport
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Deoxyuridine
spontaneous: false
left: Hydrogen Ion
left: Deoxyuridine
name: Deoxyuridine (→), Hydrogen Ion (→) Transport: Plesiomonas shigelloides 302-73, Periplasmic Space to Plesiomonas shigelloides 302-73, Cytosol
conversion direction: LEFT_TO_RIGHT

Thymidine
type: SmallMoleculeReference
xref: Reference/BioCyc THYMIDINE
xref: Reference/ChEBI CHEBI 17748
xref: Reference/CAS 50-89-5
xref: Reference/PubChem-compound 5789
xref: Reference/ChemSpider 5585
xref: Reference/HMDB HMDB0000273
xref: Reference/KEGG Compound C00214
chemical formula: C10H14N2O5
molecular weight: 242.09027
structure: ChemicalStructure/PW C000187

Transport78542
type: Transport
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Deoxyuridine
spontaneous: false
left: Hydrogen Ion
left: Deoxyuridine
name: Deoxyuridine (→), Hydrogen Ion (→) Transport: Plesiomonas shigelloides 302-73, Periplasmic Space to Plesiomonas shigelloides 302-73, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17622
type: UnificationXref
id: CHEBI:17622
db: ChEBI

Reference/ChEBI CHEBI 17748
type: UnificationXref
id: CHEBI:17748
db: ChEBI

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Compound/PW C000950/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Thymidylic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000012
type: UnificationXref
id: HMDB0000012
db: HMDB

dUMP
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17622
xref: Reference/ChemSpider 58574
xref: Reference/HMDB HMDB0001409
xref: Reference/CAS 964-26-1
xref: Reference/BioCyc DUMP
xref: Reference/PubChem-compound 65063
xref: Reference/KEGG Compound C00365
chemical formula: C9H13N2O8P
molecular weight: 308.04095
structure: ChemicalStructure/PW C001087

Reference/HMDB HMDB0000014
type: UnificationXref
id: HMDB0000014
db: HMDB

Reference/HMDB HMDB0001227
type: UnificationXref
id: HMDB0001227
db: HMDB

ChemicalStructure/PW C000179
type: ChemicalStructure
structure format: SMILES
structure data: CC1=CNC(=O)NC1=O

Reference/SMPDB SMP0479511
type: UnificationXref
id: SMP0479511
db: SMPDB

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/ChEBI CHEBI 15698
type: UnificationXref
id: CHEBI:15698
db: ChEBI

Uracil
type: SmallMolecule
entity reference: Uracil

Reference/PubChem-compound 65063
type: UnificationXref
id: 65063
db: PubChem-compound

Deoxyuridine
type: SmallMolecule
cellular location: Cytosol
entity reference: Deoxyuridine

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000187
type: ChemicalStructure
structure format: SMILES

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Reference/HMDB HMDB0001351
type: UnificationXref
id: HMDB0001351
db: HMDB

Reference/HMDB HMDB0000262
type: UnificationXref
id: HMDB0000262
db: HMDB

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Compound/PW C000204/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uracil
stoichiometric coefficient: 1.0

Reference/BioCyc URACIL
type: UnificationXref
id: URACIL
db: BioCyc

Reference/ChemSpider 5585
type: UnificationXref
id: 5585
db: ChemSpider

Reference/UniProt R8ANS3
type: UnificationXref
id: R8ANS3
db: UniProt

Reference/UniProt R8AVS1
type: UnificationXref
id: R8AVS1
db: UniProt

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C00178
type: UnificationXref
id: C00178
db: KEGG Compound

ChemicalStructure/PW C000950
type: ChemicalStructure
structure format: SMILES

dUMP
type: SmallMolecule
entity reference: dUMP

Reference/HMDB HMDB0000273
type: UnificationXref
id: HMDB0000273
db: HMDB

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 9700
type: UnificationXref
id: 9700
db: PubChem-compound

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Cytidine deaminase
type: Protein
cellular location: Cytosol
entity reference: Cytidine deaminase

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C000007 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxyuridine
stoichiometric coefficient: 1.0

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/UniProt R8ATU1
type: UnificationXref
id: R8ATU1
db: UniProt

Reference/PubChem-compound 13712
type: UnificationXref
id: 13712
db: PubChem-compound

Reference/PubChem-compound 1174
type: UnificationXref
id: 1174
db: PubChem-compound

Reference/ChEBI CHEBI 16450
type: UnificationXref
id: CHEBI:16450
db: ChEBI

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 13711
type: UnificationXref
id: 13711
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Thymidine kinase
type: Protein
entity reference: Thymidine kinase

Nucleoside permease
type: Protein
entity reference: Nucleoside permease

Reference/CAS 951-77-9
type: UnificationXref
id: 951-77-9
db: CAS

Octaprenyl diphosphate synthase
type: Protein
entity reference: Octaprenyl diphosphate synthase

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/KEGG Compound C00526
type: UnificationXref
id: C00526
db: KEGG Compound

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/BioCyc TMP
type: UnificationXref
id: TMP
db: BioCyc

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

2.7.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001087/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: dUMP
spontaneous: false
EC number: 2.7.1.21
left: Deoxyuridine
left: Adenosine triphosphate
name: Adenosine triphosphate + Deoxyuridine → Adenosine diphosphate + Hydrogen Ion + dUMP
conversion direction: LEFT_TO_RIGHT

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00881
type: UnificationXref
id: C00881
db: KEGG Compound

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reaction1287622
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001042/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000179/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000187/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Thymidine
right: Phosphate
spontaneous: false
left: Deoxyribose 1-phosphate
left: Thymine
name: Deoxyribose 1-phosphate + Thymine → Phosphate + Thymidine
conversion direction: LEFT_TO_RIGHT

Compound/PW C000008 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Deoxycytidine
stoichiometric coefficient: 1.0

2.4.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000204/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001042/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Deoxyribose 1-phosphate
right: Uracil
spontaneous: false
EC number: 2.4.2.4
left: Phosphate
left: Deoxyuridine
name: Deoxyuridine + Phosphate → Deoxyribose 1-phosphate + Uracil
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc THYMINE
type: UnificationXref
id: THYMINE
db: BioCyc

Deoxyuridine
type: SmallMolecule
entity reference: Deoxyuridine

Reaction1287624
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000008 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000007 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608 Cytosol/Stoichiometry/1.0
right: Ammonium
right: Deoxyuridine
spontaneous: false
left: Hydrogen Ion
left: Deoxycytidine
left: Water
name: Deoxycytidine + Hydrogen Ion + Water → Ammonium + Deoxyuridine
conversion direction: LEFT_TO_RIGHT

Deoxycytidine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Deoxycytidine

Reaction1287623
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000187/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000950/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: 5-Thymidylic acid
spontaneous: false
left: Thymidine
left: Adenosine triphosphate
name: Adenosine triphosphate + Thymidine → 5-Thymidylic acid + Adenosine diphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Compound/PW C001087/Stoichiometry/1.0
type: Stoichiometry
physical entity: dUMP
stoichiometric coefficient: 1.0

Reference/ChemSpider 1103
type: UnificationXref
id: 1103
db: ChemSpider

Uracil
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17568
xref: Reference/KEGG Compound C00106
xref: Reference/HMDB HMDB0000300
xref: Reference/CAS 66-22-8
xref: Reference/BioCyc URACIL
xref: Reference/PubChem-compound 1174
xref: Reference/ChemSpider 1141
chemical formula: C4H4N2O2
molecular weight: 112.027275
structure: ChemicalStructure/PW C000204

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Reference/CAS 17210-42-3
type: UnificationXref
id: 17210-42-3
db: CAS

Reference/CAS 951-78-0
type: UnificationXref
id: 951-78-0
db: CAS

ChemicalStructure/PW C001042
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H]1OC(C[C@@H]1O)OP(O)(O)=O

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/UniProt R8AM52
type: UnificationXref
id: R8AM52
db: UniProt

Ammonium
type: SmallMolecule
cellular location: Cytosol
entity reference: Ammonium

Reference/ChEBI CHEBI 28542
type: UnificationXref
id: CHEBI:28542
db: ChEBI

Reference/BioCyc DEOXYCYTIDINE
type: UnificationXref
id: DEOXYCYTIDINE
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/CAS 65-71-4
type: UnificationXref
id: 65-71-4
db: CAS

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Reference/PubChem-compound 5789
type: UnificationXref
id: 5789
db: PubChem-compound

Deoxycytidine
type: SmallMolecule
cellular location: Cytosol
entity reference: Deoxycytidine

Reference/BioCyc DEOXYURIDINE
type: UnificationXref
id: DEOXYURIDINE
db: BioCyc

Compound/PW C022608 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

3-phenylpropionic acid transporter
type: Protein
entity reference: 3-phenylpropionic acid transporter

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0