Reference/PubChem-compound 6021
type: UnificationXref
id: 6021
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/BioCyc RIBOSE-1P
type: UnificationXref
id: RIBOSE-1P
db: BioCyc

Reference/PubChem-compound 3315
type: UnificationXref
id: 3315
db: PubChem-compound

ChemicalStructure/PW C000203
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C01762
type: UnificationXref
id: C01762
db: KEGG Compound

Ribose 1-phosphate
type: SmallMolecule
entity reference: Ribose 1-phosphate

TransportCatalysis59591
type: Catalysis
controller: Nucleoside permease NupG
controlled: Transport80347
control type: ACTIVATION

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ReactionCatalysis1312181
type: Catalysis
controller: purine nucleoside phosphorylase
controlled: Reaction1280538
control type: ACTIVATION

Adenosine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 60961
xref: Reference/ChEBI CHEBI 16335
xref: Reference/ChemSpider 54923
xref: Reference/HMDB HMDB0000050
xref: Reference/CAS 58-61-7
xref: Reference/KEGG Compound C00212
xref: Reference/BioCyc ADENOSINE
chemical formula: C10H13N5O4
molecular weight: 267.09674
structure: ChemicalStructure/PW C000034

ReactionCatalysis1312180
type: Catalysis
controller: 2-amino-3-ketobutyrate coenzyme A ligase
controlled: 3.5.4.4
control type: ACTIVATION

TransportCatalysis59590
type: Catalysis
controller: Nucleoside permease NupG
controlled: Transport80346
control type: ACTIVATION

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/UniProt F9DH51
type: UnificationXref
id: F9DH51
db: UniProt

Reference/ChEBI CHEBI 17596
type: UnificationXref
id: CHEBI:17596
db: ChEBI

Compound/PW C000127/Stoichiometry/1.0
type: Stoichiometry
physical entity: Inosine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17111
type: UnificationXref
id: CHEBI:17111
db: ChEBI

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Pyruvate carboxylase subunit B
type: ProteinReference
xref: Reference/UniProt F9DJ71

ChemicalStructure/PW C000102
type: ChemicalStructure
structure format: SMILES
structure data: OC1=NC=NC2=C1NC=N2

Reference/ChEBI CHEBI 16235
type: UnificationXref
id: CHEBI:16235
db: ChEBI

Reaction1330325
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000190/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040813/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000198/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001196/Stoichiometry/1.0
right: Xanthylic acid
right: diphosphate
spontaneous: false
left: Xanthine
left: Phosphoribosyl pyrophosphate
name: Phosphoribosyl pyrophosphate + Xanthine → Xanthylic acid + diphosphate
conversion direction: LEFT_TO_RIGHT

Reaction1330328
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000024/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Ribose 1-phosphate
right: Adenine
spontaneous: false
left: Adenosine
left: Phosphate
name: Adenosine + Phosphate → Adenine + Ribose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Inosine
type: SmallMoleculeReference
xref: Reference/CAS 58-63-9
xref: Reference/PubChem-compound 6021
xref: Reference/KEGG Compound C00294
xref: Reference/BioCyc INOSINE
xref: Reference/ChemSpider 5799
xref: Reference/ChEBI CHEBI 17596
xref: Reference/HMDB HMDB0000195
chemical formula: C10H12N4O5
molecular weight: 268.08078
structure: ChemicalStructure/PW C000127

Reference/PathWhiz PW510885
type: UnificationXref
id: PW510885
db: PathWhiz

Reference/ChemSpider 58484
type: UnificationXref
id: 58484
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C00212
type: UnificationXref
id: C00212
db: KEGG Compound

Compound/PW C000102/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hypoxanthine
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

ReactionCatalysis1363302
type: Catalysis
controller: purine nucleoside phosphorylase
controlled: Reaction1330261
control type: ACTIVATION

Reference/CAS 7540-64-9
type: UnificationXref
id: 7540-64-9
db: CAS

Compound/PW C000034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine
stoichiometric coefficient: 1.0

Adenosine
type: SmallMolecule
entity reference: Adenosine

Purine Nucleotides De Novo Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway537492
pathway component: SubPathwayInteraction537492
name: SubPathway

Reference/BioCyc HYPOXANTHINE
type: UnificationXref
id: HYPOXANTHINE
db: BioCyc

Reaction1330321
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001191/Stoichiometry/1.0
right: D-Ribose 5-phosphate
spontaneous: false
left: Ribose 1-phosphate
name: Ribose 1-phosphate → D-Ribose 5-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc XANTHINE
type: UnificationXref
id: XANTHINE
db: BioCyc

Compound/PW C000087/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanosine
stoichiometric coefficient: 1.0

Compound/PW C000034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine
stoichiometric coefficient: 1.0

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Compound/PW C001146/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ribose 1-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C040813
type: ChemicalStructure
structure format: SMILES

Uridine phosphorylase
type: Protein
entity reference: Uridine phosphorylase

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Adenine
type: SmallMolecule
entity reference: Adenine

Reference/PubChem-compound 439167
type: UnificationXref
id: 439167
db: PubChem-compound

Reaction1280538
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000102/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000127/Stoichiometry/1.0
right: Ribose 1-phosphate
right: Hypoxanthine
spontaneous: false
left: Inosine
left: Phosphate
name: Inosine + Phosphate → Hypoxanthine + Ribose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Reference/UniProt F9DEB8
type: UnificationXref
id: F9DEB8
db: UniProt

Compound/PW C040813/Stoichiometry/1.0
type: Stoichiometry
physical entity: diphosphate
stoichiometric coefficient: 1.0

Adenine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000034
xref: Reference/BioCyc ADENINE
xref: Reference/PubChem-compound 190
xref: Reference/ChemSpider 185
xref: Reference/KEGG Compound C00147
xref: Reference/ChEBI CHEBI 16708
xref: Reference/CAS 73-24-5
chemical formula: C5H5N5
molecular weight: 135.05449
structure: ChemicalStructure/PW C000024

2.4.2.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000203/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000198/Stoichiometry/1.0
right: Ribose 1-phosphate
right: Xanthine
spontaneous: false
EC number: 2.4.2.1
left: Xanthosine
left: Phosphate
name: Phosphate + Xanthosine → Ribose 1-phosphate + Xanthine
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 64959
type: UnificationXref
id: 64959
db: PubChem-compound

3.5.4.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000127/Stoichiometry/1.0
right: Ammonium
right: Inosine
spontaneous: false
EC number: 3.5.4.4
left: Water
left: Adenosine
left: Hydrogen Ion
name: Adenosine + Hydrogen Ion + Water → Ammonium + Inosine
conversion direction: LEFT_TO_RIGHT

Compound/PW C000034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00119
type: UnificationXref
id: C00119
db: KEGG Compound

Reference/KEGG Compound C00117
type: UnificationXref
id: C00117
db: KEGG Compound

Reference/ChemSpider 388313
type: UnificationXref
id: 388313
db: ChemSpider

Ammonium
type: SmallMolecule
entity reference: Ammonium

Uridine phosphorylase
type: ProteinReference
xref: Reference/UniProt F9DHJ8

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

ChemicalStructure/PW C000127
type: ChemicalStructure
structure format: SMILES

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Pyruvate carboxylase subunit B
type: Protein
entity reference: Pyruvate carboxylase subunit B

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Compound/PW C000086/Stoichiometry/1.0
type: Stoichiometry
physical entity: Guanine
stoichiometric coefficient: 1.0

Phosphoribosyl pyrophosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00119
xref: Reference/ChemSpider 7062
xref: Reference/CAS 7540-64-9
xref: Reference/HMDB HMDB0000280
xref: Reference/PubChem-compound 7339
xref: Reference/BioCyc PRPP
xref: Reference/ChEBI CHEBI 17111
chemical formula: C5H13O14P3
molecular weight: 389.9518
structure: ChemicalStructure/PW C000190

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Reference/BioCyc GUANOSINE
type: UnificationXref
id: GUANOSINE
db: BioCyc

Reference/HMDB HMDB0001548
type: UnificationXref
id: HMDB0001548
db: HMDB

Xanthine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17712
xref: Reference/ChemSpider 1151
xref: Reference/KEGG Compound C00385
xref: Reference/HMDB HMDB0000292
xref: Reference/CAS 69-89-6
xref: Reference/BioCyc XANTHINE
xref: Reference/PubChem-compound 1188
chemical formula: C5H4N4O2
molecular weight: 152.03343
structure: ChemicalStructure/PW C000198

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/ChEBI CHEBI 15652
type: UnificationXref
id: CHEBI:15652
db: ChEBI

Reference/BioCyc ADENINE
type: UnificationXref
id: ADENINE
db: BioCyc

Orotate phosphoribosyltransferase
type: Protein
entity reference: Orotate phosphoribosyltransferase

Reference/ChEBI CHEBI 17712
type: UnificationXref
id: CHEBI:17712
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/ChemSpider 1151
type: UnificationXref
id: 1151
db: ChemSpider

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/PubChem-compound 790
type: UnificationXref
id: 790
db: PubChem-compound

Reference/KEGG Compound C00242
type: UnificationXref
id: C00242
db: KEGG Compound

Adenosine
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine

diphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 3315
chemical formula: C34H28N6O14S4
molecular weight: 872.0546
structure: ChemicalStructure/PW C040813

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Guanine
type: SmallMolecule
entity reference: Guanine

Reference/PubChem-compound 73323
type: UnificationXref
id: 73323
db: PubChem-compound

Reference/UniProt F9DHJ8
type: UnificationXref
id: F9DHJ8
db: UniProt

Reference/HMDB HMDB0001554
type: UnificationXref
id: HMDB0001554
db: HMDB

Reference/ChemSpider 66054
type: UnificationXref
id: 66054
db: ChemSpider

ChemicalStructure/PW C000024
type: ChemicalStructure
structure format: SMILES
structure data: NC1=C2NC=NC2=NC=N1

Guanosine
type: SmallMolecule
entity reference: Guanosine

Compound/PW C000190/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoribosyl pyrophosphate
stoichiometric coefficient: 1.0

Guanosine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000133
xref: Reference/BioCyc GUANOSINE
xref: Reference/CAS 118-00-3
xref: Reference/ChemSpider 6544
xref: Reference/PubChem-compound 6802
xref: Reference/ChEBI CHEBI 16750
xref: Reference/KEGG Compound C00387
chemical formula: C10H13N5O5
molecular weight: 283.09167
structure: ChemicalStructure/PW C000087

Guanine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 764
xref: Reference/ChEBI CHEBI 16235
xref: Reference/CAS 73-40-5
xref: Reference/BioCyc GUANINE
xref: Reference/KEGG Compound C00242
xref: Reference/HMDB HMDB0000132
xref: Reference/ChemSpider 744
chemical formula: C5H5N5O
molecular weight: 151.04941
structure: ChemicalStructure/PW C000086

Reference/PubChem-compound 60961
type: UnificationXref
id: 60961
db: PubChem-compound

2-amino-3-ketobutyrate coenzyme A ligase
type: Protein
entity reference: 2-amino-3-ketobutyrate coenzyme A ligase

Reference/ChEBI CHEBI 17368
type: UnificationXref
id: CHEBI:17368
db: ChEBI

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/BioCyc GUANINE
type: UnificationXref
id: GUANINE
db: BioCyc

Reference/CAS 118-00-3
type: UnificationXref
id: 118-00-3
db: CAS

Reference/PubChem-compound 6802
type: UnificationXref
id: 6802
db: PubChem-compound

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/PubChem-compound 7339
type: UnificationXref
id: 7339
db: PubChem-compound

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Protein/78375/Stoichiometry/4.0
type: Stoichiometry
physical entity: Orotate phosphoribosyltransferase
stoichiometric coefficient: 4.0

Compound/PW C000203/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xanthosine
stoichiometric coefficient: 1.0

Protein/92104/Stoichiometry/6.0
type: Stoichiometry
physical entity: purine-nucleoside phosphorylase
stoichiometric coefficient: 6.0

Ribose 1-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 14075-00-4
xref: Reference/ChEBI CHEBI 16300
xref: Reference/HMDB HMDB0001489
xref: Reference/PubChem-compound 439236
xref: Reference/ChemSpider 388373
xref: Reference/BioCyc RIBOSE-1P
xref: Reference/KEGG Compound C00620
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C001146

Xanthine
type: SmallMolecule
entity reference: Xanthine

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Xanthosine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Xanthosine

Reference/ChEBI CHEBI 16708
type: UnificationXref
id: CHEBI:16708
db: ChEBI

Phosphoribosyl pyrophosphate
type: SmallMolecule
entity reference: Phosphoribosyl pyrophosphate

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChEBI CHEBI 18107
type: UnificationXref
id: CHEBI:18107
db: ChEBI

Reference/CAS 68-94-0
type: UnificationXref
id: 68-94-0
db: CAS

Xanthosine
type: SmallMolecule
cellular location: Cytosol
entity reference: Xanthosine

Compound/PW C000203 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xanthosine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00385
type: UnificationXref
id: C00385
db: KEGG Compound

Reference/KEGG Compound C00262
type: UnificationXref
id: C00262
db: KEGG Compound

Reference/KEGG Compound C00147
type: UnificationXref
id: C00147
db: KEGG Compound

Reference/KEGG Compound C00387
type: UnificationXref
id: C00387
db: KEGG Compound

Purine Ribonucleosides Degradation
type: Pathway
pathway order: PathwayTransport/7090275
pathway order: PathwayEnzymeReaction/7090271
pathway order: PathwayEnzymeReaction/7090261
pathway order: PathwaySubPathway/537492
pathway order: PathwayEnzymeReaction/7090255
pathway order: PathwayEnzymeReaction/7090266
pathway order: PathwayEnzymeReaction/7090258
pathway order: PathwayEnzymeReaction/7090269
pathway order: PathwayEnzymeReaction/7090273
pathway order: PathwayTransport/7090281
pathway component: Reaction1330325
pathway component: Reaction1330328
pathway component: Transport80346
pathway component: Transport80347
pathway component: ReactionCatalysis1363371
pathway component: ReactionCatalysis1363374
pathway component: ReactionCatalysis1363364
pathway component: ReactionCatalysis1363302
pathway component: ReactionCatalysis1363368
pathway component: TransportCatalysis59591
pathway component: Reaction1330261
pathway component: Purine Nucleotides De Novo Biosynthesis
pathway component: Reaction1280538
pathway component: ReactionCatalysis1312181
pathway component: ReactionCatalysis1312180
pathway component: 2.4.2.1
pathway component: 3.5.4.4
pathway component: TransportCatalysis59590
pathway component: Reaction1330321
xref: Reference/SMPDB SMP0487476
xref: Reference/PathWhiz PW510885
organism: Prevotella pallens ATCC 700821

Reference/CAS 73-24-5
type: UnificationXref
id: 73-24-5
db: CAS

Reference/PubChem-compound 764
type: UnificationXref
id: 764
db: PubChem-compound

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ReactionCatalysis1363371
type: Catalysis
controller: purine nucleoside phosphorylase
controlled: Reaction1330328
control type: ACTIVATION

ReactionCatalysis1363374
type: Catalysis
controller: xanthosine phosphorylase
controlled: 2.4.2.1
control type: ACTIVATION

purine-nucleoside phosphorylase
type: Protein
entity reference: purine-nucleoside phosphorylase

Reference/HMDB HMDB0000133
type: UnificationXref
id: HMDB0000133
db: HMDB

Reference/CAS 146-80-5
type: UnificationXref
id: 146-80-5
db: CAS

Reference/ChEBI CHEBI 52742
type: UnificationXref
id: CHEBI:52742
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ReactionCatalysis1363368
type: Catalysis
controller: xanthine-guanine phosphoribosyltransferase
controlled: Reaction1330325
control type: ACTIVATION

Compound/PW C000024/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenine
stoichiometric coefficient: 1.0

Prevotella pallens ATCC 700821
type: BioSource
xref: Reference/TAXONOMY 997353

ChemicalStructure/PW C001146
type: ChemicalStructure
structure format: SMILES

Reaction1330261
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000087/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000086/Stoichiometry/1.0
right: Guanine
right: Ribose 1-phosphate
spontaneous: false
left: Guanosine
left: Phosphate
name: Guanosine + Phosphate → Guanine + Ribose 1-phosphate
conversion direction: LEFT_TO_RIGHT

Protein/90798/Stoichiometry/6.0
type: Stoichiometry
physical entity: Uridine phosphorylase
stoichiometric coefficient: 6.0

Reference/HMDB HMDB0000132
type: UnificationXref
id: HMDB0000132
db: HMDB

Reference/ChEBI CHEBI 16300
type: UnificationXref
id: CHEBI:16300
db: ChEBI

Reference/ChemSpider 5799
type: UnificationXref
id: 5799
db: ChemSpider

Compound/PW C001191/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribose 5-phosphate
stoichiometric coefficient: 1.0

Xanthosine
type: SmallMolecule
entity reference: Xanthosine

Reference/ChemSpider 768
type: UnificationXref
id: 768
db: ChemSpider

ReactionCatalysis1363364
type: Catalysis
controller: Pyruvate carboxylase subunit B
controlled: Reaction1330321
control type: ACTIVATION

Reference/ChemSpider 7062
type: UnificationXref
id: 7062
db: ChemSpider

Reference/CAS 73-40-5
type: UnificationXref
id: 73-40-5
db: CAS

Reference/KEGG Compound C00294
type: UnificationXref
id: C00294
db: KEGG Compound

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

xanthosine phosphorylase
type: Complex
component stoichiometry: Protein/92104/Stoichiometry/6.0
component: purine-nucleoside phosphorylase

Reference/CAS 14075-00-4
type: UnificationXref
id: 14075-00-4
db: CAS

Nucleoside permease NupG
type: ProteinReference
xref: Reference/UniProt F9DI49

xanthine-guanine phosphoribosyltransferase
type: Complex
component stoichiometry: Protein/78375/Stoichiometry/4.0
component: Orotate phosphoribosyltransferase

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChEBI CHEBI 16750
type: UnificationXref
id: CHEBI:16750
db: ChEBI

Compound/PW C001196/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xanthylic acid
stoichiometric coefficient: 1.0

diphosphate
type: SmallMolecule
entity reference: diphosphate

Reference/HMDB HMDB0000034
type: UnificationXref
id: HMDB0000034
db: HMDB

Reference/HMDB HMDB0001489
type: UnificationXref
id: HMDB0001489
db: HMDB

Reference/HMDB HMDB0000157
type: UnificationXref
id: HMDB0000157
db: HMDB

Reference/BioCyc INOSINE
type: UnificationXref
id: INOSINE
db: BioCyc

Reference/SMPDB SMP0487476
type: UnificationXref
id: SMP0487476
db: SMPDB

ChemicalStructure/PW C000034
type: ChemicalStructure
structure format: SMILES

purine nucleoside phosphorylase
type: Complex
component stoichiometry: Protein/90798/Stoichiometry/6.0
component: Uridine phosphorylase

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Compound/PW C000203 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xanthosine
stoichiometric coefficient: 1.0

Reference/ChemSpider 6544
type: UnificationXref
id: 6544
db: ChemSpider

Nucleoside permease NupG
type: Protein
entity reference: Nucleoside permease NupG

purine-nucleoside phosphorylase
type: ProteinReference
xref: Reference/UniProt F9DH51

Reference/BioCyc XANTHOSINE-5-PHOSPHATE
type: UnificationXref
id: XANTHOSINE-5-PHOSPHATE
db: BioCyc

Reference/CAS 58-61-7
type: UnificationXref
id: 58-61-7
db: CAS

Reference/KEGG Compound C00620
type: UnificationXref
id: C00620
db: KEGG Compound

Xanthylic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15652
xref: Reference/PubChem-compound 73323
xref: Reference/HMDB HMDB0001554
xref: Reference/KEGG Compound C00655
xref: Reference/ChemSpider 66054
xref: Reference/CAS 523-98-8
xref: Reference/BioCyc XANTHOSINE-5-PHOSPHATE
chemical formula: C10H13N4O9P
molecular weight: 364.04202
structure: ChemicalStructure/PW C001196

Xanthylic acid
type: SmallMolecule
entity reference: Xanthylic acid
name: SubPathwayInput

Reference/HMDB HMDB0000280
type: UnificationXref
id: HMDB0000280
db: HMDB

D-Ribose 5-phosphate
type: SmallMolecule
entity reference: D-Ribose 5-phosphate

D-Ribose 5-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00117
xref: Reference/ChEBI CHEBI 52742
xref: Reference/ChemSpider 388313
xref: Reference/HMDB HMDB0001548
xref: Reference/BioCyc RIBOSE-5P
xref: Reference/PubChem-compound 439167
xref: Reference/CAS 4300-28-1
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C001191

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChEBI CHEBI 16335
type: UnificationXref
id: CHEBI:16335
db: ChEBI

Reference/TAXONOMY 997353
type: UnificationXref
id: 997353
db: TAXONOMY

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000299
type: UnificationXref
id: HMDB0000299
db: HMDB

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/PubChem-compound 439236
type: UnificationXref
id: 439236
db: PubChem-compound

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/HMDB HMDB0000292
type: UnificationXref
id: HMDB0000292
db: HMDB

Reference/HMDB HMDB0000050
type: UnificationXref
id: HMDB0000050
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/BioCyc ADENOSINE
type: UnificationXref
id: ADENOSINE
db: BioCyc

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Inosine
type: SmallMolecule
entity reference: Inosine

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001196
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc RIBOSE-5P
type: UnificationXref
id: RIBOSE-5P
db: BioCyc

ChemicalStructure/PW C001191
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00655
type: UnificationXref
id: C00655
db: KEGG Compound

Xanthosine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000299
xref: Reference/CAS 146-80-5
xref: Reference/ChEBI CHEBI 18107
xref: Reference/ChemSpider 58484
xref: Reference/PubChem-compound 64959
xref: Reference/KEGG Compound C01762
chemical formula: C10H12N4O6
molecular weight: 284.07568
structure: ChemicalStructure/PW C000203

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Reference/ChemSpider 388373
type: UnificationXref
id: 388373
db: ChemSpider

Reference/CAS 69-89-6
type: UnificationXref
id: 69-89-6
db: CAS

Reference/UniProt F9DI49
type: UnificationXref
id: F9DI49
db: UniProt

Orotate phosphoribosyltransferase
type: ProteinReference
xref: Reference/UniProt F9DEB8

Reference/BioCyc PRPP
type: UnificationXref
id: PRPP
db: BioCyc

Reference/CAS 58-63-9
type: UnificationXref
id: 58-63-9
db: CAS

ChemicalStructure/PW C000198
type: ChemicalStructure
structure format: SMILES
structure data: O=C1NC2=C(NC=N2)C(=O)N1

SubPathwayInteraction537492
type: Interaction
name: SubPathway537492Reaction
name: SubPathwayReaction
participant: Xanthylic acid

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/PubChem-compound 190
type: UnificationXref
id: 190
db: PubChem-compound

ChemicalStructure/PW C000190
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 54923
type: UnificationXref
id: 54923
db: ChemSpider

Adenosine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Adenosine

Reference/HMDB HMDB0000195
type: UnificationXref
id: HMDB0000195
db: HMDB

Compound/PW C000198/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xanthine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/UniProt F9DJ71
type: UnificationXref
id: F9DJ71
db: UniProt

Reference/CAS 523-98-8
type: UnificationXref
id: 523-98-8
db: CAS

Transport80346
type: Transport
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000034 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Adenosine
spontaneous: false
left: Hydrogen Ion
left: Adenosine
name: Adenosine (→), Hydrogen Ion (→) Transport: Prevotella pallens ATCC 700821, Periplasmic Space to Prevotella pallens ATCC 700821, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Transport80347
type: Transport
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000203 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000203 Periplasmic Space/Stoichiometry/1.0
right: Xanthosine
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: Xanthosine
name: Xanthosine (→), Hydrogen Ion (→) Transport: Prevotella pallens ATCC 700821, Periplasmic Space to Prevotella pallens ATCC 700821, Cytosol
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Hypoxanthine
type: SmallMolecule
entity reference: Hypoxanthine

Reference/UniProt F9DEN8
type: UnificationXref
id: F9DEN8
db: UniProt

Reference/ChemSpider 744
type: UnificationXref
id: 744
db: ChemSpider

Reference/PubChem-compound 1188
type: UnificationXref
id: 1188
db: PubChem-compound

ChemicalStructure/PW C000087
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000086
type: ChemicalStructure
structure format: SMILES
structure data: NC1=NC(=O)C2=C(N1)N=CN2

2-amino-3-ketobutyrate coenzyme A ligase
type: ProteinReference
xref: Reference/UniProt F9DEN8

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Hypoxanthine
type: SmallMoleculeReference
xref: Reference/CAS 68-94-0
xref: Reference/HMDB HMDB0000157
xref: Reference/ChEBI CHEBI 17368
xref: Reference/PubChem-compound 790
xref: Reference/KEGG Compound C00262
xref: Reference/BioCyc HYPOXANTHINE
xref: Reference/ChemSpider 768
chemical formula: C5H4N4O
molecular weight: 136.03851
structure: ChemicalStructure/PW C000102

Reference/ChemSpider 185
type: UnificationXref
id: 185
db: ChemSpider

Reference/CAS 4300-28-1
type: UnificationXref
id: 4300-28-1
db: CAS