Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

L-Valine
type: SmallMoleculeReference
xref: Reference/CAS 72-18-4
xref: Reference/PubChem-compound 6287
xref: Reference/ChemSpider 6050
xref: Reference/HMDB HMDB0000883
xref: Reference/KEGG Compound C00183
xref: Reference/ChEBI CHEBI 16414
xref: Reference/BioCyc VAL
chemical formula: C5H11NO2
molecular weight: 117.07898
structure: ChemicalStructure/PW C000704

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

ChemicalStructure/PW C000448
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CS)C(O)=O

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/BioCyc CYS
type: UnificationXref
id: CYS
db: BioCyc

Compound/PW C001009/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Alanine
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/HMDB HMDB0003364
type: UnificationXref
id: HMDB0003364
db: HMDB

D-amino acid dehydrogenase
type: Complex
component stoichiometry: Protein/28346/Stoichiometry/2.0
component: Unknown

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

D-Alanine
type: SmallMoleculeReference
xref: Reference/BioCyc D-ALANINE
xref: Reference/HMDB HMDB0001310
xref: Reference/ChemSpider 64234
xref: Reference/KEGG Compound C00133
xref: Reference/PubChem-compound 71080
xref: Reference/CAS 338-69-2
xref: Reference/ChEBI CHEBI 15570
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C001009

Reference/ChEBI CHEBI 17594
type: UnificationXref
id: CHEBI:17594
db: ChEBI

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 64234
type: UnificationXref
id: 64234
db: ChemSpider

Reference/ChemSpider 48
type: UnificationXref
id: 48
db: ChemSpider

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Compound/PW C001009/Stoichiometry/2.0
type: Stoichiometry
physical entity: D-Alanine
stoichiometric coefficient: 2.0

Reference/PubChem-compound 6287
type: UnificationXref
id: 6287
db: PubChem-compound

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

D-Alanine
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Alanine

an [L-cysteine desulfurase] L-cysteine persulfide
type: SmallMolecule
cellular location: Cytosol
entity reference: an [L-cysteine desulfurase] L-cysteine persulfide

D-Alanine
type: SmallMolecule
entity reference: D-Alanine

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/ChEBI CHEBI 17561
type: UnificationXref
id: CHEBI:17561
db: ChEBI

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/CAS 759-05-7
type: UnificationXref
id: 759-05-7
db: CAS

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

α-Ketoisovaleric acid
type: SmallMoleculeReference
xref: Reference/CAS 759-05-7
xref: Reference/PubChem-compound 49
xref: Reference/ChemSpider 48
xref: Reference/HMDB HMDB0000019
xref: Reference/BioCyc 2-KETO-ISOVALERATE
xref: Reference/KEGG Compound C00141
xref: Reference/ChEBI CHEBI 16530
chemical formula: C5H8O3
molecular weight: 116.04734
structure: ChemicalStructure/PW C000012

L-Valine
type: SmallMolecule
entity reference: L-Valine

Reference/ChemSpider 5735
type: UnificationXref
id: 5735
db: ChemSpider

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

D-Alanyl-D-alanine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16576
xref: Reference/ChemSpider 4573916
xref: Reference/HMDB HMDB0003459
xref: Reference/BioCyc D-ALA-D-ALA
xref: Reference/CAS 923-16-0
xref: Reference/KEGG Compound C00993
xref: Reference/PubChem-compound 5460362
chemical formula: C6H12N2O3
molecular weight: 160.0848
structure: ChemicalStructure/PW C001900

Reference/PubChem-compound 5862
type: UnificationXref
id: 5862
db: PubChem-compound

Reference/PubChem-compound 4650
type: UnificationXref
id: 4650
db: PubChem-compound

Compound/PW C001009 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Alanine
stoichiometric coefficient: 1.0

Reference/BioCyc 2-KETO-ISOVALERATE
type: UnificationXref
id: 2-KETO-ISOVALERATE
db: BioCyc

Compound/PW C000012/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-Ketoisovaleric acid
stoichiometric coefficient: 1.0

Protein/28346 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Ammonium
type: SmallMolecule
entity reference: Ammonium

L-Alanine Metabolism
type: Pathway
pathway order: PathwaySubPathway/545125
pathway order: PathwaySubPathway/545124
pathway order: PathwaySubPathway/545123
pathway order: PathwayEnzymeReaction/7149399
pathway order: PathwayEnzymeReaction/7149389
pathway order: PathwayEnzymeReaction/7149400
pathway order: PathwayEnzymeReaction/7149387
pathway order: PathwayEnzymeReaction/7149395
pathway order: PathwayEnzymeReaction/7149396
pathway order: PathwayEnzymeReaction/7149393
pathway component: 2.8.1.7
pathway component: 6.3.2.4
pathway component: 1.4.99.1
pathway component: Reaction580055
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: 2.6.1.42
pathway component: ReactionCatalysis573721
pathway component: ReactionCatalysis1390173
pathway component: 2.6.1.66
pathway component: ReactionCatalysis573722
pathway component: ReactionCatalysis1390171
pathway component: 2.6.1.2
pathway component: L-Glutamate Metabolism
pathway component: Cysteine Biosynthesis
pathway component: ReactionCatalysis1390174
pathway component: ReactionCatalysis1390169
pathway component: ReactionCatalysis1390167
xref: Reference/SMPDB SMP0492157
xref: Reference/PathWhiz PW516416
organism: Escherichia coli W

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/ChEBI CHEBI 16977
type: UnificationXref
id: CHEBI:16977
db: ChEBI

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/BioCyc 236-TRICHLOROHYDROQUINONE
type: UnificationXref
id: 236-TRICHLOROHYDROQUINONE
db: BioCyc

Reference/KEGG Compound C00472
type: UnificationXref
id: C00472
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/TAXONOMY 566546
type: UnificationXref
id: 566546
db: TAXONOMY

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

SubPathwayInteraction545125
type: Interaction
name: SubPathway545125Reaction
name: SubPathwayReaction
participant: L-Glutamic acid

Reference/HMDB HMDB0000574
type: UnificationXref
id: HMDB0000574
db: HMDB

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Quinone
type: SmallMolecule
entity reference: Quinone

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

ChemicalStructure/PW C000012
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)C(=O)C(O)=O

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/BioCyc D-ALANINE
type: UnificationXref
id: D-ALANINE
db: BioCyc

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

6.3.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001009/Stoichiometry/2.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001900/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Adenosine diphosphate
right: D-Alanyl-D-alanine
right: Phosphate
spontaneous: false
EC number: 6.3.2.4
left: D-Alanine
left: Adenosine triphosphate
name: Adenosine triphosphate + 2 D-Alanine → Adenosine diphosphate + D-Alanyl-D-alanine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reaction580055
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001009 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000105 Cytosol/Stoichiometry/1.0
right: D-Alanine
spontaneous: false
left: L-Alanine
name: L-Alanine → D-Alanine
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001900
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](N)C(=O)N[C@H](C)C(O)=O

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc L-ALPHA-ALANINE
type: UnificationXref
id: L-ALPHA-ALANINE
db: BioCyc

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/CAS 56-41-7
type: UnificationXref
id: 56-41-7
db: CAS

Reference/PathWhiz PW516416
type: UnificationXref
id: PW516416
db: PathWhiz

Compound/PW C001900/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Alanyl-D-alanine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

SubPathwayInteraction545124
type: Interaction
name: SubPathwayReaction
name: SubPathway545124Reaction
participant: L-Cysteine

Reference/HMDB HMDB0001310
type: UnificationXref
id: HMDB0001310
db: HMDB

SubPathwayInteraction545123
type: Interaction
name: SubPathway545123Reaction
name: SubPathwayReaction
participant: Pyruvic acid

Reference/ChemSpider 6050
type: UnificationXref
id: 6050
db: ChemSpider

Valine Transaminase
type: Complex
component stoichiometry: Protein/28346/Stoichiometry/6.0
component: Unknown

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/PubChem-compound 49
type: UnificationXref
id: 49
db: PubChem-compound

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway545123
pathway component: SubPathwayInteraction545123
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Pyruvic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyruvic acid
name: SubPathwayInput

Reference/KEGG Compound C00133
type: UnificationXref
id: C00133
db: KEGG Compound

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

ChemicalStructure/PW C000105
type: ChemicalStructure
structure format: SMILES
structure data: C[C@H](N)C(O)=O

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

cysteine desulfurase
type: Complex
component stoichiometry: Protein/28346 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Unknown

Reference/PubChem-compound 5950
type: UnificationXref
id: 5950
db: PubChem-compound

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

L-Glutamate Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway545125
pathway component: SubPathwayInteraction545125
xref: Reference/SMPDB SMP0000811
xref: Reference/PathWhiz PW000789
name: SubPathway

Protein/28346/Stoichiometry/6.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 6.0

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

glutamate-pyruvate aminotransferase
type: Complex
component stoichiometry: Protein/28346/Stoichiometry/2.0
component: Unknown

Reference/KEGG Compound C00141
type: UnificationXref
id: C00141
db: KEGG Compound

Reference/ChemSpider 5653
type: UnificationXref
id: 5653
db: ChemSpider

L-Glutamic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamic acid
name: SubPathwayInput

Reference/CAS 338-69-2
type: UnificationXref
id: 338-69-2
db: CAS

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/ChemSpider 4573916
type: UnificationXref
id: 4573916
db: ChemSpider

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Compound/Generic101 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: an [L-cysteine desulfurase] L-cysteine persulfide
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Compound/PW C000704/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Valine
stoichiometric coefficient: 1.0

Cysteine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway545124
pathway component: SubPathwayInteraction545124
xref: Reference/SMPDB SMP0000821
xref: Reference/PathWhiz PW000800
name: SubPathway

Unknown
type: Protein
entity reference: Unknown

Reference/ChEBI CHEBI 16414
type: UnificationXref
id: CHEBI:16414
db: ChEBI

Hydroquinone
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0002434
xref: Reference/ChemSpider 764
xref: Reference/PubChem-compound 785
xref: Reference/CAS 123-31-9
xref: Reference/BioCyc 236-TRICHLOROHYDROQUINONE
xref: Reference/ChEBI CHEBI 17594
xref: Reference/KEGG Compound C00530
chemical formula: C6H6O2
molecular weight: 110.03678
structure: ChemicalStructure/PW C001632

Reference/CAS 52-90-4
type: UnificationXref
id: 52-90-4
db: CAS

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/ChEBI CHEBI 16530
type: UnificationXref
id: CHEBI:16530
db: ChEBI

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/HMDB HMDB0002434
type: UnificationXref
id: HMDB0002434
db: HMDB

Water
type: SmallMolecule
entity reference: Water

Reference/KEGG Compound C00041
type: UnificationXref
id: C00041
db: KEGG Compound

Reference/HMDB HMDB0000019
type: UnificationXref
id: HMDB0000019
db: HMDB

Compound/PW C001860/Stoichiometry/1.0
type: Stoichiometry
physical entity: Quinone
stoichiometric coefficient: 1.0

Compound/PW C000448 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Cysteine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5460362
type: UnificationXref
id: 5460362
db: PubChem-compound

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/SMPDB SMP0000811
type: UnificationXref
id: SMP0000811
db: SMPDB

Reference/ChEBI CHEBI 15570
type: UnificationXref
id: CHEBI:15570
db: ChEBI

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 764
type: UnificationXref
id: 764
db: ChemSpider

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Compound/PW C000105 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Alanine
stoichiometric coefficient: 1.0

Compound/PW C001632/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydroquinone
stoichiometric coefficient: 1.0

2.8.1.7
type: BiochemicalReaction
participant stoichiometry: Compound/Generic101 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000105 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000448 Cytosol/Stoichiometry/1.0
right: an [L-cysteine desulfurase] L-cysteine persulfide
right: L-Alanine
spontaneous: false
EC number: 2.8.1.7
left: L-Cysteine
left: an [L-cysteine desulfurase] L-cysteine persulfide
name: L-Cysteine + an [L-cysteine desulfurase] L-cysteine persulfide → L-Alanine + an [L-cysteine desulfurase] L-cysteine persulfide
conversion direction: LEFT_TO_RIGHT

1.4.99.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001632/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001860/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001009/Stoichiometry/1.0
right: Ammonium
right: Pyruvic acid
right: Hydroquinone
spontaneous: false
EC number: 1.4.99.1
left: Water
left: Quinone
left: D-Alanine
name: D-Alanine + Quinone + Water → Ammonium + Hydroquinone + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

2.6.1.42
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000704/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000012/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: L-Valine
right: Oxoglutaric acid
spontaneous: false
EC number: 2.6.1.42
left: L-Glutamic acid
left: α-Ketoisovaleric acid
name: L-Glutamic acid + α-Ketoisovaleric acid → L-Valine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 785
type: UnificationXref
id: 785
db: PubChem-compound

ReactionCatalysis1390173
type: Catalysis
controller: D-amino acid dehydrogenase
controlled: 1.4.99.1
control type: ACTIVATION

Reference/SMPDB SMP0000821
type: UnificationXref
id: SMP0000821
db: SMPDB

2.6.1.66
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000105/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000704/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000012/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
right: α-Ketoisovaleric acid
right: L-Alanine
spontaneous: false
EC number: 2.6.1.66
left: L-Valine
left: Pyruvic acid
name: L-Valine + Pyruvic acid → L-Alanine + α-Ketoisovaleric acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis1390171
type: Catalysis
controller: Valine Transaminase
controlled: 2.6.1.42
control type: ACTIVATION

2.6.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000105/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: Oxoglutaric acid
right: L-Alanine
spontaneous: false
EC number: 2.6.1.2
left: L-Glutamic acid
left: Pyruvic acid
name: L-Glutamic acid + Pyruvic acid → L-Alanine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

ChemicalStructure/PW C000704
type: ChemicalStructure
structure format: SMILES
structure data: CC(C)[C@H](N)C(O)=O

Reference/CAS 72-18-4
type: UnificationXref
id: 72-18-4
db: CAS

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Reference/KEGG Compound C00183
type: UnificationXref
id: C00183
db: KEGG Compound

Quinone
type: SmallMoleculeReference
xref: Reference/ChemSpider 4489
xref: Reference/CAS 106-51-4
xref: Reference/KEGG Compound C00472
xref: Reference/ChEBI CHEBI 16509
xref: Reference/BioCyc CPD-8130
xref: Reference/PubChem-compound 4650
xref: Reference/HMDB HMDB0003364
chemical formula: C6H4O2
molecular weight: 108.021126
structure: ChemicalStructure/PW C001860

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/SMPDB SMP0492157
type: UnificationXref
id: SMP0492157
db: SMPDB

Reference/ChEBI CHEBI 16509
type: UnificationXref
id: CHEBI:16509
db: ChEBI

ReactionCatalysis1390169
type: Catalysis
controller: Unknown
controlled: 2.6.1.66
control type: ACTIVATION

ReactionCatalysis1390167
type: Catalysis
controller: glutamate-pyruvate aminotransferase
controlled: 2.6.1.2
control type: ACTIVATION

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

ReactionCatalysis573721
type: Catalysis
controller: Unknown
controlled: 6.3.2.4
control type: ACTIVATION

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/ChemSpider 4489
type: UnificationXref
id: 4489
db: ChemSpider

ReactionCatalysis573722
type: Catalysis
controller: Unknown
controlled: Reaction580055
control type: ACTIVATION

ChemicalStructure/PW C001009
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](N)C(O)=O

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-8130
type: UnificationXref
id: CPD-8130
db: BioCyc

Hydroquinone
type: SmallMolecule
entity reference: Hydroquinone

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/PubChem-compound 71080
type: UnificationXref
id: 71080
db: PubChem-compound

Reference/CAS 123-31-9
type: UnificationXref
id: 123-31-9
db: CAS

Reference/HMDB HMDB0000161
type: UnificationXref
id: HMDB0000161
db: HMDB

Reference/PathWhiz PW000789
type: UnificationXref
id: PW000789
db: PathWhiz

ReactionCatalysis1390174
type: Catalysis
controller: cysteine desulfurase
controlled: 2.8.1.7
control type: ACTIVATION

Reference/CAS 923-16-0
type: UnificationXref
id: 923-16-0
db: CAS

Reference/ChEBI CHEBI 16576
type: UnificationXref
id: CHEBI:16576
db: ChEBI

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

L-Alanine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00041
xref: Reference/ChemSpider 5735
xref: Reference/ChEBI CHEBI 16977
xref: Reference/BioCyc L-ALPHA-ALANINE
xref: Reference/HMDB HMDB0000161
xref: Reference/CAS 56-41-7
xref: Reference/PubChem-compound 5950
chemical formula: C3H7NO2
molecular weight: 89.047676
structure: ChemicalStructure/PW C000105

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

L-Alanine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Alanine

D-Alanyl-D-alanine
type: SmallMolecule
entity reference: D-Alanyl-D-alanine

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/KEGG Compound C00993
type: UnificationXref
id: C00993
db: KEGG Compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Compound/PW C000105/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Alanine
stoichiometric coefficient: 1.0

α-Ketoisovaleric acid
type: SmallMolecule
entity reference: α-Ketoisovaleric acid

ChemicalStructure/PW C001860
type: ChemicalStructure
structure format: SMILES
structure data: O=C1C=CC(=O)C=C1

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Escherichia coli W
type: BioSource
xref: Reference/TAXONOMY 566546

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

L-Cysteine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Cysteine
name: SubPathwayOutput

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc VAL
type: UnificationXref
id: VAL
db: BioCyc

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001632
type: ChemicalStructure
structure format: SMILES
structure data: OC1=CC=C(O)C=C1

Reference/HMDB HMDB0003459
type: UnificationXref
id: HMDB0003459
db: HMDB

Reference/PathWhiz PW000800
type: UnificationXref
id: PW000800
db: PathWhiz

L-Cysteine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000574
xref: Reference/CAS 52-90-4
xref: Reference/KEGG Compound C00097
xref: Reference/BioCyc CYS
xref: Reference/ChemSpider 5653
xref: Reference/PubChem-compound 5862
xref: Reference/ChEBI CHEBI 17561
chemical formula: C3H7NO2S
molecular weight: 121.01975
structure: ChemicalStructure/PW C000448

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Reference/KEGG Compound C00097
type: UnificationXref
id: C00097
db: KEGG Compound

Reference/KEGG Compound C00530
type: UnificationXref
id: C00530
db: KEGG Compound

Protein/28346/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Unknown
type: ProteinReference

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

L-Alanine
type: SmallMolecule
entity reference: L-Alanine

Reference/CAS 106-51-4
type: UnificationXref
id: 106-51-4
db: CAS

Reference/BioCyc D-ALA-D-ALA
type: UnificationXref
id: D-ALA-D-ALA
db: BioCyc

Reference/HMDB HMDB0000883
type: UnificationXref
id: HMDB0000883
db: HMDB

an [L-cysteine desulfurase] L-cysteine persulfide
type: SmallMoleculeReference