UDP-α-D-galactose
type: SmallMolecule
entity reference: UDP-α-D-galactose
name: SubPathwayOutput

Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/HMDB HMDB0062573
type: UnificationXref
id: HMDB0062573
db: HMDB

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 3315
type: UnificationXref
id: 3315
db: PubChem-compound

SubPathwayInteraction557390
type: Interaction
name: SubPathway557390Reaction
name: SubPathwayReaction
participant: β-D-Glucose 6-phosphate

NADH
type: SmallMolecule
entity reference: NADH

dTDP-D-glucose
type: SmallMolecule
entity reference: dTDP-D-glucose

Protein/28268/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

dTDP-glucose pyrophosphorylase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/4.0
component: Unknown

UDP-D-Galacto-1,4-furanose
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25244316
xref: Reference/ChEBI CHEBI 18251
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C041141

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Escherichia coli UMN026
type: BioSource
xref: Reference/TAXONOMY 585056

ReactionCatalysis1437639
type: Catalysis
controller: phosphoglucose isomerase
controlled: Reaction1399117
control type: ACTIVATION

Reference/PubChem-compound 6133
type: UnificationXref
id: 6133
db: PubChem-compound

ReactionCatalysis1437638
type: Catalysis
controller: Unknown
controlled: Reaction1399116
control type: ACTIVATION

SubPathwayInteraction557388
type: Interaction
name: SubPathway557388Reaction
name: SubPathwayReaction
participant: UDP-α-D-galactose

ChemicalStructure/PW C042657
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis1437637
type: Catalysis
controller: D-fructose-6-phosphate aminotransferase
controlled: Reaction1399115
control type: ACTIVATION

SubPathwayInteraction557389
type: Interaction
name: SubPathwayReaction
name: SubPathway557389Reaction
participant: Uridine diphosphate-N-acetylglucosamine

ChemicalStructure/PW C042658
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis1437636
type: Catalysis
controller: Unknown
controlled: Reaction1399114
control type: ACTIVATION

Reference/KEGG Compound C00688
type: UnificationXref
id: C00688
db: KEGG Compound

SubPathwayInteraction557387
type: Interaction
name: SubPathwayReaction
name: SubPathway557387Reaction
participant: α-D-Glucose 1-phosphate

ReactionCatalysis1437634
type: Catalysis
controller: dTDP-glucose 4,6-dehydratase
controlled: Reaction1399113
control type: ACTIVATION

Compound/PW C001906/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis1437632
type: Catalysis
controller: dTDP-glucose pyrophosphorylase
controlled: 2.7.7.24
control type: ACTIVATION

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Reference/ChEBI CHEBI 16264
type: UnificationXref
id: CHEBI:16264
db: ChEBI

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/CAS 528-04-1
type: UnificationXref
id: 528-04-1
db: CAS

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Compound/PW C042580/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-glucosamine 6-phosphate
stoichiometric coefficient: 1.0

Galactose Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway557387
pathway component: SubPathwayInteraction557387
xref: Reference/SMPDB SMP0000841
xref: Reference/PathWhiz PW000821
name: SubPathway

Reference/HMDB HMDB0003498
type: UnificationXref
id: HMDB0003498
db: HMDB

Compound/PW C044520/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-β-L-rhamnose
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00459
type: UnificationXref
id: C00459
db: KEGG Compound

Reference/ChemSpider 388455
type: UnificationXref
id: 388455
db: ChemSpider

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 365-08-2
type: UnificationXref
id: 365-08-2
db: CAS

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/KEGG Compound C04256
type: UnificationXref
id: C04256
db: KEGG Compound

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Protein/28268/Stoichiometry/3.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 3.0

Reference/PubChem-compound 64968
type: UnificationXref
id: 64968
db: PubChem-compound

Lipopolysaccharide Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway557389
pathway component: SubPathwayInteraction557389
xref: Reference/PathWhiz PW000831
xref: Reference/SMPDB SMP0000851
name: SubPathway

Reference/ChemSpider 393240
type: UnificationXref
id: 393240
db: ChemSpider

Reference/ChemSpider 8140645
type: UnificationXref
id: 8140645
db: ChemSpider

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

β-D-Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388538
xref: Reference/KEGG Compound C01172
xref: Reference/ChEBI CHEBI 17719
xref: Reference/HMDB HMDB0003498
xref: Reference/PubChem-compound 439427
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001906

UDP-α-D-galactose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0062573
xref: Reference/ChEBI CHEBI 58439
chemical formula: C15H24N2O17P2
molecular weight: 566.055
structure: ChemicalStructure/PW C040993

Reference/PathWhiz PW000831
type: UnificationXref
id: PW000831
db: PathWhiz

Reference/ChEBI CHEBI 15713
type: UnificationXref
id: CHEBI:15713
db: ChEBI

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Reference/ChemSpider 58493
type: UnificationXref
id: 58493
db: ChemSpider

ChemicalStructure/PW C040813
type: ChemicalStructure
structure format: SMILES

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

NADP
type: SmallMolecule
entity reference: NADP

Reference/BioCyc GLUCOSAMINE-1P
type: UnificationXref
id: GLUCOSAMINE-1P
db: BioCyc

Reference/PubChem-compound 440272
type: UnificationXref
id: 440272
db: PubChem-compound

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Compound/PW C040813/Stoichiometry/1.0
type: Stoichiometry
physical entity: diphosphate
stoichiometric coefficient: 1.0

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/PathWhiz PW000821
type: UnificationXref
id: PW000821
db: PathWhiz

Unknown
type: Protein
entity reference: Unknown

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Glucosamine-1P
type: SmallMoleculeReference
xref: Reference/PubChem-compound 9965052
xref: Reference/BioCyc GLUCOSAMINE-1P
xref: Reference/HMDB HMDB0001109
xref: Reference/ChemSpider 8140645
chemical formula: C6H14NO8P
molecular weight: 259.04572
structure: ChemicalStructure/PW C000868

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Compound/PW C000868/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glucosamine-1P
stoichiometric coefficient: 1.0

Galactose Degradation/Leloir Pathway
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway557388
pathway component: SubPathwayInteraction557388
xref: Reference/SMPDB SMP0000903
xref: Reference/PathWhiz PW000884
name: SubPathway

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Reference/SMPDB SMP0000841
type: UnificationXref
id: SMP0000841
db: SMPDB

D-fructose-6-phosphate aminotransferase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/2.0
component: Unknown

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Uridine triphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 6133
xref: Reference/CAS 63-39-8
xref: Reference/ChemSpider 5903
xref: Reference/ChEBI CHEBI 15713
xref: Reference/KEGG Compound C00075
xref: Reference/HMDB HMDB0000285
xref: Reference/BioCyc UTP
chemical formula: C9H15N2O15P3
molecular weight: 483.96854
structure: ChemicalStructure/PW C000192

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Protein/28268/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Compound/PW C041141/Stoichiometry/1.0
type: Stoichiometry
physical entity: UDP-D-Galacto-1,4-furanose
stoichiometric coefficient: 1.0

Uridine diphosphate-N-acetylglucosamine
type: SmallMoleculeReference
xref: Reference/CAS 528-04-1
xref: Reference/PubChem-compound 445675
xref: Reference/HMDB HMDB0000290
xref: Reference/BioCyc UDP-N-ACETYL-D-GLUCOSAMINE
xref: Reference/KEGG Compound C00043
xref: Reference/ChEBI CHEBI 16264
xref: Reference/ChemSpider 393240
chemical formula: C17H27N3O17P2
molecular weight: 607.08154
structure: ChemicalStructure/PW C000196

Compound/PW C042658/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-4-dehydro-6-deoxy-D-glucose
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001906
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

β-D-fructofuranose 6-phosphate
type: SmallMolecule
entity reference: β-D-fructofuranose 6-phosphate

Compound/PW C000500/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Amino Sugar and Nucleotide Sugar Metabolism III
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway557390
pathway component: SubPathwayInteraction557390
xref: Reference/SMPDB SMP0000914
xref: Reference/PathWhiz PW000895
name: SubPathway

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/PathWhiz PW000895
type: UnificationXref
id: PW000895
db: PathWhiz

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

phosphoglucose isomerase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/2.0
component: Unknown

diphosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 3315
chemical formula: C34H28N6O14S4
molecular weight: 872.0546
structure: ChemicalStructure/PW C040813

α-D-Glucose 1-phosphate
type: SmallMolecule
entity reference: α-D-Glucose 1-phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 35248
type: UnificationXref
id: CHEBI:35248
db: ChEBI

Reference/HMDB HMDB0060081
type: UnificationXref
id: HMDB0060081
db: HMDB

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

N-Acetyl-glucosamine 1-phosphate
type: SmallMolecule
entity reference: N-Acetyl-glucosamine 1-phosphate

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

N-Acetyl-glucosamine 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 7125
xref: Reference/ChemSpider 389248
xref: Reference/HMDB HMDB0001367
xref: Reference/PubChem-compound 440272
xref: Reference/BioCyc N-ACETYL-D-GLUCOSAMINE-1-P
xref: Reference/CAS 6866-69-9
xref: Reference/KEGG Compound C04256
chemical formula: C8H16NO9P
molecular weight: 301.05627
structure: ChemicalStructure/PW C001055

Compound/PW C040941/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-fructofuranose 6-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Compound/PW C042657/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-6-deoxy-L-mannose
stoichiometric coefficient: 1.0

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/SMPDB SMP0000851
type: UnificationXref
id: SMP0000851
db: SMPDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/ChemSpider 388538
type: UnificationXref
id: 388538
db: ChemSpider

β-D-fructofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57634
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040941

ReactionCatalysis1437588
type: Catalysis
controller: fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase
controlled: Reaction1399067
control type: ACTIVATION

Reference/PathWhiz PW000884
type: UnificationXref
id: PW000884
db: PathWhiz

ReactionCatalysis1437587
type: Catalysis
controller: Unknown
controlled: Reaction1399066
control type: ACTIVATION

fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/3.0
component: Unknown

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

α-D-Glucose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58601
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C040949

Reference/ChEBI CHEBI 7125
type: UnificationXref
id: CHEBI:7125
db: ChEBI

Uridine diphosphate-N-acetylglucosamine
type: SmallMolecule
entity reference: Uridine diphosphate-N-acetylglucosamine
name: SubPathwayInput

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

dTDP-D-glucose
type: SmallMoleculeReference
xref: Reference/ChemSpider 388455
xref: Reference/KEGG Compound C00842
xref: Reference/PubChem-compound 439324
xref: Reference/HMDB HMDB0001328
xref: Reference/CAS 2196-62-5
xref: Reference/ChEBI CHEBI 35248
xref: Reference/BioCyc DTDP-D-GLUCOSE
chemical formula: C16H26N2O16P2
molecular weight: 564.07574
structure: ChemicalStructure/PW C001024

Reference/HMDB HMDB0001328
type: UnificationXref
id: HMDB0001328
db: HMDB

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Compound/PW C001055/Stoichiometry/1.0
type: Stoichiometry
physical entity: N-Acetyl-glucosamine 1-phosphate
stoichiometric coefficient: 1.0

UDP-D-Galacto-1,4-furanose
type: SmallMolecule
entity reference: UDP-D-Galacto-1,4-furanose

Uridine triphosphate
type: SmallMolecule
entity reference: Uridine triphosphate

ChemicalStructure/PW C043042
type: ChemicalStructure
structure format: SMILES

dTDP-glucose 4,6-dehydratase
type: Complex
component stoichiometry: Protein/28268/Stoichiometry/2.0
component: Unknown

2.7.7.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000868/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001055/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: N-Acetyl-glucosamine 1-phosphate
right: Coenzyme A
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.7.23
left: Acetyl-CoA
left: Glucosamine-1P
name: Acetyl-CoA + Glucosamine-1P → Coenzyme A + Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate
conversion direction: LEFT_TO_RIGHT

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C001035/Stoichiometry/1.0
type: Stoichiometry
physical entity: Thymidine 5'-triphosphate
stoichiometric coefficient: 1.0

Reference/TAXONOMY 585056
type: UnificationXref
id: 585056
db: TAXONOMY

dTDP-4-dehydro-β-L-rhamnose
type: SmallMolecule
entity reference: dTDP-4-dehydro-β-L-rhamnose

Reference/PubChem-compound 25244316
type: UnificationXref
id: 25244316
db: PubChem-compound

L-Glutamine
type: SmallMolecule
entity reference: L-Glutamine

Glucosamine-1P
type: SmallMolecule
entity reference: Glucosamine-1P

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/ChEBI CHEBI 58439
type: UnificationXref
id: CHEBI:58439
db: ChEBI

Thymidine 5'-triphosphate
type: SmallMolecule
entity reference: Thymidine 5'-triphosphate

Thymidine 5'-triphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00459
xref: Reference/CAS 365-08-2
xref: Reference/ChEBI CHEBI 18077
xref: Reference/ChemSpider 58493
xref: Reference/PubChem-compound 64968
xref: Reference/HMDB HMDB0001342
xref: Reference/BioCyc TTP
chemical formula: C10H17N2O14P3
molecular weight: 481.98926
structure: ChemicalStructure/PW C001035

D-glucosamine 6-phosphate
type: SmallMolecule
entity reference: D-glucosamine 6-phosphate

D-glucosamine 6-phosphate
type: SmallMoleculeReference
chemical formula: C6H14NO8P
molecular weight: 259.04572
structure: ChemicalStructure/PW C042580

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

dTDP-4-dehydro-β-L-rhamnose
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 45868
xref: Reference/KEGG Compound C00688
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C044520

Reference/BioCyc TTP
type: UnificationXref
id: TTP
db: BioCyc

dTDP-6-deoxy-L-mannose
type: SmallMolecule
entity reference: dTDP-6-deoxy-L-mannose

Reference/BioCyc N-ACETYL-D-GLUCOSAMINE-1-P
type: UnificationXref
id: N-ACETYL-D-GLUCOSAMINE-1-P
db: BioCyc

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMolecule
entity reference: dTDP-4-dehydro-6-deoxy-D-glucose

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/SMPDB SMP0501763
type: UnificationXref
id: SMP0501763
db: SMPDB

ChemicalStructure/PW C001024
type: ChemicalStructure
structure format: SMILES

TDP-Rhamnose
type: SmallMoleculeReference
chemical formula: C17H26N2O14P2
molecular weight: 544.08594
structure: ChemicalStructure/PW C043042

Reference/HMDB HMDB0001342
type: UnificationXref
id: HMDB0001342
db: HMDB

ChemicalStructure/PW C040993
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00842
type: UnificationXref
id: C00842
db: KEGG Compound

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/HMDB HMDB0001109
type: UnificationXref
id: HMDB0001109
db: HMDB

Reference/KEGG Compound C00043
type: UnificationXref
id: C00043
db: KEGG Compound

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Reference/PathWhiz PW527570
type: UnificationXref
id: PW527570
db: PathWhiz

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Compound/PW C000196/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine diphosphate-N-acetylglucosamine
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

ChemicalStructure/PW C001035
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc UTP
type: UnificationXref
id: UTP
db: BioCyc

Reference/PubChem-compound 439427
type: UnificationXref
id: 439427
db: PubChem-compound

Reference/ChemSpider 5903
type: UnificationXref
id: 5903
db: ChemSpider

ReactionCatalysis1185488
type: Catalysis
controller: Unknown
controlled: 5.1.3.13
control type: ACTIVATION

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Compound/PW C043042/Stoichiometry/1.0
type: Stoichiometry
physical entity: TDP-Rhamnose
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 18251
type: UnificationXref
id: CHEBI:18251
db: ChEBI

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

diphosphate
type: SmallMolecule
entity reference: diphosphate

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/HMDB HMDB0001367
type: UnificationXref
id: HMDB0001367
db: HMDB

Unknown
type: ProteinReference

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/ChEBI CHEBI 17719
type: UnificationXref
id: CHEBI:17719
db: ChEBI

Compound/PW C000192/Stoichiometry/1.0
type: Stoichiometry
physical entity: Uridine triphosphate
stoichiometric coefficient: 1.0

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

5.4.99.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041141/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040993/Stoichiometry/1.0
right: UDP-D-Galacto-1,4-furanose
spontaneous: false
EC number: 5.4.99.9
left: UDP-α-D-galactose
name: UDP-α-D-galactose ↔ UDP-D-Galacto-1,4-furanose
conversion direction: REVERSIBLE

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

2.7.7.24
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040949/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001035/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040813/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: dTDP-D-glucose
right: diphosphate
spontaneous: false
EC number: 2.7.7.24
left: Thymidine 5'-triphosphate
left: Hydrogen Ion
left: α-D-Glucose 1-phosphate
name: Hydrogen Ion + Thymidine 5'-triphosphate + α-D-Glucose 1-phosphate → dTDP-D-glucose + diphosphate
conversion direction: LEFT_TO_RIGHT

Reaction1399114
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042657/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: dTDP-6-deoxy-L-mannose
right: NADP
spontaneous: false
left: dTDP-4-dehydro-β-L-rhamnose
left: Hydrogen Ion
left: NADPH
name: Hydrogen Ion + NADPH + dTDP-4-dehydro-β-L-rhamnose → NADP + dTDP-6-deoxy-L-mannose
conversion direction: LEFT_TO_RIGHT

Reaction1399113
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042658/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001024/Stoichiometry/1.0
right: Water
right: dTDP-4-dehydro-6-deoxy-D-glucose
spontaneous: false
left: dTDP-D-glucose
name: dTDP-D-glucose → Water + dTDP-4-dehydro-6-deoxy-D-glucose
conversion direction: LEFT_TO_RIGHT

5.1.3.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042658/Stoichiometry/1.0
right: dTDP-4-dehydro-β-L-rhamnose
spontaneous: false
EC number: 5.1.3.13
left: dTDP-4-dehydro-6-deoxy-D-glucose
name: dTDP-4-dehydro-6-deoxy-D-glucose → dTDP-4-dehydro-β-L-rhamnose
conversion direction: LEFT_TO_RIGHT

Reaction1399116
type: BiochemicalReaction
participant stoichiometry: Compound/PW C044520/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043042/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADP
right: TDP-Rhamnose
spontaneous: false
left: NADH
left: dTDP-4-dehydro-β-L-rhamnose
left: Hydrogen Ion
name: Hydrogen Ion + NADH + dTDP-4-dehydro-β-L-rhamnose → NADP + TDP-Rhamnose
conversion direction: LEFT_TO_RIGHT

Reaction1399115
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042580/Stoichiometry/1.0
right: L-Glutamic acid
right: D-glucosamine 6-phosphate
spontaneous: false
left: β-D-fructofuranose 6-phosphate
left: L-Glutamine
name: L-Glutamine + β-D-fructofuranose 6-phosphate ↔ D-glucosamine 6-phosphate + L-Glutamic acid
conversion direction: REVERSIBLE

dTDP-4-dehydro-6-deoxy-D-glucose
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0060081
chemical formula: C16H24N2O15P2
molecular weight: 546.0652
structure: ChemicalStructure/PW C042658

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

dTDP-6-deoxy-L-mannose
type: SmallMoleculeReference
chemical formula: C16H26N2O15P2
molecular weight: 548.0809
structure: ChemicalStructure/PW C042657

Reaction1399117
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001906/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040941/Stoichiometry/1.0
right: β-D-fructofuranose 6-phosphate
spontaneous: false
left: β-D-Glucose 6-phosphate
name: β-D-Glucose 6-phosphate ↔ β-D-fructofuranose 6-phosphate
conversion direction: REVERSIBLE

Reference/PubChem-compound 445675
type: UnificationXref
id: 445675
db: PubChem-compound

Reference/BioCyc UDP-N-ACETYL-D-GLUCOSAMINE
type: UnificationXref
id: UDP-N-ACETYL-D-GLUCOSAMINE
db: BioCyc

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/CAS 6866-69-9
type: UnificationXref
id: 6866-69-9
db: CAS

ReactionCatalysis859940
type: Catalysis
controller: Unknown
controlled: 5.4.99.9
control type: ACTIVATION

Reference/BioCyc DTDP-D-GLUCOSE
type: UnificationXref
id: DTDP-D-GLUCOSE
db: BioCyc

Reference/PubChem-compound 439324
type: UnificationXref
id: 439324
db: PubChem-compound

Compound/PW C001024/Stoichiometry/1.0
type: Stoichiometry
physical entity: dTDP-D-glucose
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000285
type: UnificationXref
id: HMDB0000285
db: HMDB

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reaction1399067
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000196/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001055/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040813/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000192/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Uridine diphosphate-N-acetylglucosamine
right: diphosphate
spontaneous: false
left: N-Acetyl-glucosamine 1-phosphate
left: Hydrogen Ion
left: Uridine triphosphate
name: Hydrogen Ion + N-Acetyl-glucosamine 1-phosphate + Uridine triphosphate → Uridine diphosphate-N-acetylglucosamine + diphosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 389248
type: UnificationXref
id: 389248
db: ChemSpider

ChemicalStructure/PW C040941
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

β-D-Glucose 6-phosphate
type: SmallMolecule
entity reference: β-D-Glucose 6-phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 18077
type: UnificationXref
id: CHEBI:18077
db: ChEBI

Reference/KEGG Compound C00075
type: UnificationXref
id: C00075
db: KEGG Compound

ChemicalStructure/PW C040949
type: ChemicalStructure
structure format: SMILES

Reaction1399066
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000868/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042580/Stoichiometry/1.0
right: Glucosamine-1P
spontaneous: false
left: D-glucosamine 6-phosphate
name: D-glucosamine 6-phosphate ↔ Glucosamine-1P
conversion direction: REVERSIBLE

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/PubChem-compound 9965052
type: UnificationXref
id: 9965052
db: PubChem-compound

Reference/KEGG Compound C01172
type: UnificationXref
id: C01172
db: KEGG Compound

Reference/HMDB HMDB0000290
type: UnificationXref
id: HMDB0000290
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Compound/PW C040993/Stoichiometry/1.0
type: Stoichiometry
physical entity: UDP-α-D-galactose
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 45868
type: UnificationXref
id: CHEBI:45868
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

O-Antigen Building Blocks Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/7261301
pathway order: PathwayEnzymeReaction/7261302
pathway order: PathwayEnzymeReaction/7261303
pathway order: PathwayEnzymeReaction/7261297
pathway order: PathwayEnzymeReaction/7261298
pathway order: PathwayEnzymeReaction/7261299
pathway order: PathwaySubPathway/557389
pathway order: PathwayEnzymeReaction/7261294
pathway order: PathwayEnzymeReaction/7261295
pathway order: PathwaySubPathway/557387
pathway order: PathwayEnzymeReaction/7261296
pathway order: PathwaySubPathway/557388
pathway order: PathwayEnzymeReaction/7261290
pathway order: PathwayEnzymeReaction/7261292
pathway order: PathwaySubPathway/557390
pathway component: Reaction1399067
pathway component: ReactionCatalysis1185488
pathway component: Galactose Degradation/Leloir Pathway
pathway component: ReactionCatalysis1437588
pathway component: ReactionCatalysis1437587
pathway component: Reaction1399066
pathway component: Lipopolysaccharide Biosynthesis
pathway component: ReactionCatalysis1437639
pathway component: 5.4.99.9
pathway component: 2.7.7.23
pathway component: ReactionCatalysis1437638
pathway component: 2.7.7.24
pathway component: ReactionCatalysis1437637
pathway component: Reaction1399114
pathway component: ReactionCatalysis1437636
pathway component: Reaction1399113
pathway component: 5.1.3.13
pathway component: ReactionCatalysis1437634
pathway component: Reaction1399116
pathway component: Reaction1399115
pathway component: Amino Sugar and Nucleotide Sugar Metabolism III
pathway component: ReactionCatalysis1437632
pathway component: Reaction1399117
pathway component: ReactionCatalysis859940
pathway component: ReactionCatalysis840508
pathway component: Galactose Metabolism
xref: Reference/SMPDB SMP0501763
xref: Reference/PathWhiz PW527570
organism: Escherichia coli UMN026

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/CAS 2196-62-5
type: UnificationXref
id: 2196-62-5
db: CAS

ChemicalStructure/PW C044520
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C042580
type: ChemicalStructure
structure format: SMILES

Compound/PW C040949/Stoichiometry/1.0
type: Stoichiometry
physical entity: α-D-Glucose 1-phosphate
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0000903
type: UnificationXref
id: SMP0000903
db: SMPDB

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

ChemicalStructure/PW C000868
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

ChemicalStructure/PW C000196
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

TDP-Rhamnose
type: SmallMolecule
entity reference: TDP-Rhamnose

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

ChemicalStructure/PW C000192
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C041141
type: ChemicalStructure
structure format: SMILES

Reference/CAS 63-39-8
type: UnificationXref
id: 63-39-8
db: CAS

Reference/SMPDB SMP0000914
type: UnificationXref
id: SMP0000914
db: SMPDB

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/ChEBI CHEBI 58601
type: UnificationXref
id: CHEBI:58601
db: ChEBI

Reference/ChEBI CHEBI 57634
type: UnificationXref
id: CHEBI:57634
db: ChEBI

ReactionCatalysis840508
type: Catalysis
controller: fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase
controlled: 2.7.7.23
control type: ACTIVATION

ChemicalStructure/PW C001055
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS