Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChEBI CHEBI 15721
type: UnificationXref
id: CHEBI:15721
db: ChEBI

Ribose-5-phosphate isomerase B
type: ProteinReference
xref: Reference/UniProt P37351

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Glucose-6-phosphate 1-dehydrogenase
type: ProteinReference
xref: Reference/UniProt P0AC53

Reference/HMDB HMDB0001068
type: UnificationXref
id: HMDB0001068
db: HMDB

ChemicalStructure/PW C000691
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)[C@@H](O)[C@H](O)COP(O)(O)=O

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/CAS 2641-81-8
type: UnificationXref
id: 2641-81-8
db: CAS

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C001906/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Chorismate Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway562816
pathway component: SubPathwayInteraction562816
xref: Reference/SMPDB SMP0000836
xref: Reference/PathWhiz PW000816
name: SubPathway

D-Erythrose 4-phosphate
type: SmallMolecule
entity reference: D-Erythrose 4-phosphate

6-phosphogluconate dehydrogenase, decarboxylating
type: Protein
entity reference: 6-phosphogluconate dehydrogenase, decarboxylating

6-Phosphogluconic acid
type: SmallMolecule
entity reference: 6-Phosphogluconic acid

5.1.3.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000479/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000691/Stoichiometry/1.0
right: Xylulose 5-phosphate
spontaneous: false
EC number: 5.1.3.1
left: D-Ribulose 5-phosphate
name: D-Ribulose 5-phosphate ↔ Xylulose 5-phosphate
conversion direction: REVERSIBLE

1.1.1.44
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001015/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000479/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
right: D-Ribulose 5-phosphate
right: Carbon dioxide
right: NADPH
spontaneous: false
EC number: 1.1.1.44
left: NADP
left: 6-Phosphogluconic acid
name: 6-Phosphogluconic acid + NADP → Carbon dioxide + D-Ribulose 5-phosphate + NADPH
conversion direction: LEFT_TO_RIGHT

5.3.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000479/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001191/Stoichiometry/1.0
right: D-Ribose 5-phosphate
spontaneous: false
EC number: 5.3.1.6
left: D-Ribulose 5-phosphate
name: D-Ribulose 5-phosphate ↔ D-Ribose 5-phosphate
conversion direction: REVERSIBLE

D-Sedoheptulose 7-phosphate
type: SmallMolecule
entity reference: D-Sedoheptulose 7-phosphate

6-Phosphogluconic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 48928
xref: Reference/BioCyc CPD-2961
xref: Reference/HMDB HMDB0001316
xref: Reference/CAS 921-62-0
xref: Reference/PubChem-compound 91493
xref: Reference/ChemSpider 82615
xref: Reference/KEGG Compound C00345
chemical formula: C6H13O10P
molecular weight: 276.02463
structure: ChemicalStructure/PW C001015

Reference/ChEBI CHEBI 16938
type: UnificationXref
id: CHEBI:16938
db: ChEBI

Reference/HMDB HMDB0003498
type: UnificationXref
id: HMDB0003498
db: HMDB

6-phosphogluconate dehydrogenase, decarboxylating
type: ProteinReference

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/UniProt P52697
type: UnificationXref
id: P52697
db: UniProt

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/PubChem-compound 439184
type: UnificationXref
id: 439184
db: PubChem-compound

Transketolase 1
type: ProteinReference
xref: Reference/UniProt P27302

Reference/KEGG Compound C05345
type: UnificationXref
id: C05345
db: KEGG Compound

Reference/ChemSpider 388330
type: UnificationXref
id: 388330
db: ChemSpider

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Ribulose-phosphate 3-epimerase
type: Protein
entity reference: Ribulose-phosphate 3-epimerase

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

β-D-Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388538
xref: Reference/KEGG Compound C01172
xref: Reference/ChEBI CHEBI 17719
xref: Reference/HMDB HMDB0003498
xref: Reference/PubChem-compound 439427
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001906

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

Reference/CAS 2646-35-7
type: UnificationXref
id: 2646-35-7
db: CAS

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/KEGG Compound C00345
type: UnificationXref
id: C00345
db: KEGG Compound

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Protein/94937/Stoichiometry/2.0
type: Stoichiometry
physical entity: 6-phosphogluconate dehydrogenase, decarboxylating
stoichiometric coefficient: 2.0

NADP
type: SmallMolecule
entity reference: NADP

Reference/PubChem-compound 439167
type: UnificationXref
id: 439167
db: PubChem-compound

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/UniProt P0AC53
type: UnificationXref
id: P0AC53
db: UniProt

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/KEGG Compound C00117
type: UnificationXref
id: C00117
db: KEGG Compound

Reference/ChemSpider 388313
type: UnificationXref
id: 388313
db: ChemSpider

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/BioCyc CPD-2961
type: UnificationXref
id: CPD-2961
db: BioCyc

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/ChemSpider 388559
type: UnificationXref
id: 388559
db: ChemSpider

Reference/ChemSpider 389526
type: UnificationXref
id: 389526
db: ChemSpider

Reference/KEGG Compound C00231
type: UnificationXref
id: C00231
db: KEGG Compound

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/HMDB HMDB0001548
type: UnificationXref
id: HMDB0001548
db: HMDB

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

ChemicalStructure/PW C001906
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/PubChem-compound 122357
type: UnificationXref
id: 122357
db: PubChem-compound

Reference/CAS 921-62-0
type: UnificationXref
id: 921-62-0
db: CAS

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/PubChem-compound 439190
type: UnificationXref
id: 439190
db: PubChem-compound

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

allose-6-phosphate isomerase / ribose-5-phosphate isomerase B
type: Complex
component stoichiometry: Protein/6569/Stoichiometry/2.0
component: Ribose-5-phosphate isomerase B

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

β-D-Fructose 6-phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440641
xref: Reference/ChemSpider 389526
xref: Reference/ChEBI CHEBI 16084
xref: Reference/KEGG Compound C05345
xref: Reference/BioCyc FRUCTOSE-6P
xref: Reference/HMDB HMDB0003971
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C002021

6-Phosphonoglucono-D-lactone
type: SmallMolecule
entity reference: 6-Phosphonoglucono-D-lactone

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

β-D-Fructose 6-phosphate
type: SmallMolecule
entity reference: β-D-Fructose 6-phosphate

Reference/HMDB HMDB0001316
type: UnificationXref
id: HMDB0001316
db: HMDB

Ribose-5-phosphate isomerase A
type: Protein
entity reference: Ribose-5-phosphate isomerase A

6-Phosphonoglucono-D-lactone
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001127
xref: Reference/PubChem-compound 439452
xref: Reference/ChemSpider 388559
xref: Reference/ChEBI CHEBI 16938
xref: Reference/KEGG Compound C01236
xref: Reference/CAS 2641-81-8
xref: Reference/BioCyc D-6-P-GLUCONO-DELTA-LACTONE
chemical formula: C6H11O9P
molecular weight: 258.01407
structure: ChemicalStructure/PW C000881

Reference/HMDB HMDB0003971
type: UnificationXref
id: HMDB0003971
db: HMDB

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway562815
pathway component: SubPathwayInteraction562815
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Reference/ChemSpider 388538
type: UnificationXref
id: 388538
db: ChemSpider

D-Sedoheptulose 7-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001068
xref: Reference/ChemSpider 17216052
xref: Reference/BioCyc D-SEDOHEPTULOSE-7-P
xref: Reference/PubChem-compound 22833559
xref: Reference/ChEBI CHEBI 15721
xref: Reference/KEGG Compound C00281
xref: Reference/CAS 2646-35-7
chemical formula: C7H15O10P
molecular weight: 290.04028
structure: ChemicalStructure/PW C000843

PRPP Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway562817
pathway component: SubPathwayInteraction562817
xref: Reference/PathWhiz PW000909
xref: Reference/SMPDB SMP0000926
name: SubPathway

Protein/6074/Stoichiometry/2.0
type: Stoichiometry
physical entity: Transaldolase B
stoichiometric coefficient: 2.0

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/UniProt P0A7Z0
type: UnificationXref
id: P0A7Z0
db: UniProt

D-Erythrose 4-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 48153
xref: Reference/HMDB HMDB0001321
xref: Reference/CAS 585-18-2
xref: Reference/BioCyc ERYTHROSE-4P
xref: Reference/PubChem-compound 122357
xref: Reference/ChemSpider 109096
xref: Reference/KEGG Compound C00279
chemical formula: C4H9O7P
molecular weight: 200.00859
structure: ChemicalStructure/PW C001019

Reference/BioCyc FRUCTOSE-6P
type: UnificationXref
id: FRUCTOSE-6P
db: BioCyc

Reference/ChEBI CHEBI 17363
type: UnificationXref
id: CHEBI:17363
db: ChEBI

Reference/PubChem-compound 440641
type: UnificationXref
id: 440641
db: PubChem-compound

Reference/HMDB HMDB0001321
type: UnificationXref
id: HMDB0001321
db: HMDB

1.1.1.49
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000881/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: 6-Phosphonoglucono-D-lactone
right: Hydrogen Ion
right: NADPH
spontaneous: false
EC number: 1.1.1.49
left: NADP
left: β-D-Glucose 6-phosphate
name: NADP + β-D-Glucose 6-phosphate → 6-Phosphonoglucono-D-lactone + Hydrogen Ion + NADPH
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

6-phosphogluconate dehydrogenase, decarboxylating
type: Complex
component stoichiometry: Protein/94937/Stoichiometry/2.0
component: 6-phosphogluconate dehydrogenase, decarboxylating

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Reference/CAS 60802-29-1
type: UnificationXref
id: 60802-29-1
db: CAS

Transaldolase A
type: Protein
entity reference: Transaldolase A

Transaldolase B
type: Protein
entity reference: Transaldolase B

Reference/SMPDB SMP0506991
type: UnificationXref
id: SMP0506991
db: SMPDB

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Compound/PW C001015/Stoichiometry/1.0
type: Stoichiometry
physical entity: 6-Phosphogluconic acid
stoichiometric coefficient: 1.0

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
entity reference: D-Glyceraldehyde 3-phosphate

SubPathwayInteraction562816
type: Interaction
name: SubPathwayReaction
name: SubPathway562816Reaction

Compound/PW C000881/Stoichiometry/1.0
type: Stoichiometry
physical entity: 6-Phosphonoglucono-D-lactone
stoichiometric coefficient: 1.0

SubPathwayInteraction562817
type: Interaction
name: SubPathway562817Reaction
name: SubPathwayReaction

Reference/BioCyc ERYTHROSE-4P
type: UnificationXref
id: ERYTHROSE-4P
db: BioCyc

SubPathwayInteraction562815
type: Interaction
name: SubPathway562815Reaction
name: SubPathwayReaction

ChemicalStructure/PW C000479
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)[C@H](O)[C@H](O)COP(O)(O)=O

Ribulose-phosphate 3-epimerase
type: ProteinReference
xref: Reference/UniProt P0AG07

Reference/KEGG Compound C01236
type: UnificationXref
id: C01236
db: KEGG Compound

Reference/CAS 4151-19-3
type: UnificationXref
id: 4151-19-3
db: CAS

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 48928
type: UnificationXref
id: CHEBI:48928
db: ChEBI

ChemicalStructure/PW C000843
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001019
type: ChemicalStructure
structure format: SMILES
structure data: O[C@H](COP(O)(O)=O)[C@@H](O)C=O

Reference/ChemSpider 82615
type: UnificationXref
id: 82615
db: ChemSpider

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/KEGG Compound C00279
type: UnificationXref
id: C00279
db: KEGG Compound

Reference/SMPDB SMP0000926
type: UnificationXref
id: SMP0000926
db: SMPDB

Xylulose 5-phosphate
type: SmallMolecule
entity reference: Xylulose 5-phosphate

6-phosphogluconolactonase
type: Protein
entity reference: 6-phosphogluconolactonase

Reference/ChEBI CHEBI 52742
type: UnificationXref
id: CHEBI:52742
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

Reference/ChemSpider 17216052
type: UnificationXref
id: 17216052
db: ChemSpider

Reference/KEGG Compound C00281
type: UnificationXref
id: C00281
db: KEGG Compound

Reference/UniProt P37351
type: UnificationXref
id: P37351
db: UniProt

ReactionCatalysis1457544
type: Catalysis
controller: allose-6-phosphate isomerase / ribose-5-phosphate isomerase B
controlled: 5.3.1.6
control type: ACTIVATION

ReactionCatalysis1457543
type: Catalysis
controller: Ribulose-phosphate 3-epimerase
controlled: 5.1.3.1
control type: ACTIVATION

ReactionCatalysis1457542
type: Catalysis
controller: 6-phosphogluconate dehydrogenase, decarboxylating
controlled: 1.1.1.44
control type: ACTIVATION

Compound/PW C002021/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Fructose 6-phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis1457541
type: Catalysis
controller: Glucose-6-phosphate 1-dehydrogenase
controlled: 1.1.1.49
control type: ACTIVATION

Reference/BioCyc D-SEDOHEPTULOSE-7-P
type: UnificationXref
id: D-SEDOHEPTULOSE-7-P
db: BioCyc

ReactionCatalysis1457548
type: Catalysis
controller: Transketolase 2
controlled: Reaction1418500
control type: ACTIVATION

ReactionCatalysis1457547
type: Catalysis
controller: Transketolase I
controlled: Reaction1418500
control type: ACTIVATION

Reference/UniProt P27302
type: UnificationXref
id: P27302
db: UniProt

ReactionCatalysis1457545
type: Catalysis
controller: Ribose-5-phosphate isomerase A
controlled: 5.3.1.6
control type: ACTIVATION

Compound/PW C001191/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribose 5-phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Protein/6060/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ribose-5-phosphate isomerase A
stoichiometric coefficient: 2.0

Transketolase 2
type: Protein
entity reference: Transketolase 2

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Ribose-5-phosphate isomerase A
type: ProteinReference
xref: Reference/UniProt P0A7Z0

Transaldolase B
type: Complex
component stoichiometry: Protein/6074/Stoichiometry/2.0
component: Transaldolase B

Reference/PubChem-compound 91493
type: UnificationXref
id: 91493
db: PubChem-compound

Ribose-5-phosphate isomerase A
type: Complex
component stoichiometry: Protein/6060/Stoichiometry/2.0
component: Ribose-5-phosphate isomerase A

Reference/PubChem-compound 439427
type: UnificationXref
id: 439427
db: PubChem-compound

Transketolase I
type: Complex
component stoichiometry: Protein/6466/Stoichiometry/2.0
component: Transketolase 1

Compound/PW C000691/Stoichiometry/1.0
type: Stoichiometry
physical entity: Xylulose 5-phosphate
stoichiometric coefficient: 1.0

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Compound/PW C001019/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Erythrose 4-phosphate
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/UniProt P0A870
type: UnificationXref
id: P0A870
db: UniProt

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

Reference/ChEBI CHEBI 48153
type: UnificationXref
id: CHEBI:48153
db: ChEBI

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Transaldolase B
type: ProteinReference
xref: Reference/UniProt P0A870

Reference/PubChem-compound 22833559
type: UnificationXref
id: 22833559
db: PubChem-compound

Transaldolase A
type: ProteinReference
xref: Reference/UniProt P0A867

Reference/HMDB HMDB0001127
type: UnificationXref
id: HMDB0001127
db: HMDB

Reference/UniProt P0A867
type: UnificationXref
id: P0A867
db: UniProt

Reference/PubChem-compound 439452
type: UnificationXref
id: 439452
db: PubChem-compound

Reference/CAS 585-18-2
type: UnificationXref
id: 585-18-2
db: CAS

Reference/UniProt P33570
type: UnificationXref
id: P33570
db: UniProt

Reference/ChEBI CHEBI 17719
type: UnificationXref
id: CHEBI:17719
db: ChEBI

Reference/BioCyc D-6-P-GLUCONO-DELTA-LACTONE
type: UnificationXref
id: D-6-P-GLUCONO-DELTA-LACTONE
db: BioCyc

Reference/SMPDB SMP0000836
type: UnificationXref
id: SMP0000836
db: SMPDB

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/ChEBI CHEBI 16084
type: UnificationXref
id: CHEBI:16084
db: ChEBI

Ribose-5-phosphate isomerase B
type: Protein
entity reference: Ribose-5-phosphate isomerase B

ChemicalStructure/PW C001015
type: ChemicalStructure
structure format: SMILES

Glucose-6-phosphate 1-dehydrogenase
type: Protein
entity reference: Glucose-6-phosphate 1-dehydrogenase

D-Ribose 5-phosphate
type: SmallMolecule
entity reference: D-Ribose 5-phosphate

Protein/6569/Stoichiometry/2.0
type: Stoichiometry
physical entity: Ribose-5-phosphate isomerase B
stoichiometric coefficient: 2.0

D-Ribose 5-phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00117
xref: Reference/ChEBI CHEBI 52742
xref: Reference/ChemSpider 388313
xref: Reference/HMDB HMDB0001548
xref: Reference/BioCyc RIBOSE-5P
xref: Reference/PubChem-compound 439167
xref: Reference/CAS 4300-28-1
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C001191

Pentose Phosphate Pathway
type: Pathway
pathway order: PathwayEnzymeReaction/7300638
pathway order: PathwayEnzymeReaction/7300639
pathway order: PathwayEnzymeReaction/7300655
pathway order: PathwaySubPathway/562817
pathway order: PathwayEnzymeReaction/7300646
pathway order: PathwaySubPathway/562815
pathway order: PathwayEnzymeReaction/7300647
pathway order: PathwaySubPathway/562816
pathway order: PathwayEnzymeReaction/7300651
pathway order: PathwayEnzymeReaction/7300641
pathway order: PathwayEnzymeReaction/7300642
pathway order: PathwayEnzymeReaction/7300643
pathway order: PathwayEnzymeReaction/7300650
pathway component: ReactionCatalysis1457544
pathway component: ReactionCatalysis1457543
pathway component: ReactionCatalysis1457554
pathway component: ReactionCatalysis1457542
pathway component: ReactionCatalysis1457553
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: ReactionCatalysis1457541
pathway component: ReactionCatalysis1457548
pathway component: PRPP Biosynthesis
pathway component: ReactionCatalysis1457547
pathway component: Reaction1418504
pathway component: Chorismate Biosynthesis
pathway component: ReactionCatalysis1457545
pathway component: 3.1.1.31
pathway component: ReactionCatalysis1457556
pathway component: Reaction1418500
pathway component: 5.1.3.1
pathway component: 1.1.1.44
pathway component: 5.3.1.6
pathway component: 1.1.1.49
xref: Reference/SMPDB SMP0506991
xref: Reference/PathWhiz PW533141
organism: Escherichia coli

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reaction1418504
type: BiochemicalReaction
participant stoichiometry: Compound/PW C002021/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000843/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001019/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: β-D-Fructose 6-phosphate
right: D-Erythrose 4-phosphate
spontaneous: false
left: D-Glyceraldehyde 3-phosphate
left: D-Sedoheptulose 7-phosphate
name: D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate ↔ D-Erythrose 4-phosphate + β-D-Fructose 6-phosphate
conversion direction: REVERSIBLE

β-D-Glucose 6-phosphate
type: SmallMolecule
entity reference: β-D-Glucose 6-phosphate

Reference/BioCyc RIBULOSE-5P
type: UnificationXref
id: RIBULOSE-5P
db: BioCyc

3.1.1.31
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001015/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000881/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Hydrogen Ion
right: 6-Phosphogluconic acid
spontaneous: false
EC number: 3.1.1.31
left: Water
left: 6-Phosphonoglucono-D-lactone
name: 6-Phosphonoglucono-D-lactone + Water → 6-Phosphogluconic acid + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00199
type: UnificationXref
id: C00199
db: KEGG Compound

Reaction1418500
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000843/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000691/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001191/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: D-Glyceraldehyde 3-phosphate
right: D-Sedoheptulose 7-phosphate
spontaneous: false
left: Xylulose 5-phosphate
left: D-Ribose 5-phosphate
name: D-Ribose 5-phosphate + Xylulose 5-phosphate ↔ D-Glyceraldehyde 3-phosphate + D-Sedoheptulose 7-phosphate
conversion direction: REVERSIBLE

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/ChEBI CHEBI 16332
type: UnificationXref
id: CHEBI:16332
db: ChEBI

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/KEGG Compound C01172
type: UnificationXref
id: C01172
db: KEGG Compound

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/PathWhiz PW533141
type: UnificationXref
id: PW533141
db: PathWhiz

Reference/PathWhiz PW000816
type: UnificationXref
id: PW000816
db: PathWhiz

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

D-Ribulose 5-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 4151-19-3
xref: Reference/BioCyc RIBULOSE-5P
xref: Reference/KEGG Compound C00199
xref: Reference/PubChem-compound 439184
xref: Reference/HMDB HMDB0000618
xref: Reference/ChEBI CHEBI 17363
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C000479

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/HMDB HMDB0000618
type: UnificationXref
id: HMDB0000618
db: HMDB

6-phosphogluconolactonase
type: ProteinReference
xref: Reference/UniProt P52697

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Compound/PW C000843/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Sedoheptulose 7-phosphate
stoichiometric coefficient: 1.0

Reference/BioCyc RIBOSE-5P
type: UnificationXref
id: RIBOSE-5P
db: BioCyc

Transketolase 1
type: Protein
entity reference: Transketolase 1

ChemicalStructure/PW C001191
type: ChemicalStructure
structure format: SMILES

Compound/PW C000869/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis1457554
type: Catalysis
controller: Transaldolase B
controlled: Reaction1418504
control type: ACTIVATION

ReactionCatalysis1457553
type: Catalysis
controller: Transaldolase A
controlled: Reaction1418504
control type: ACTIVATION

ReactionCatalysis1457556
type: Catalysis
controller: 6-phosphogluconolactonase
controlled: 3.1.1.31
control type: ACTIVATION

D-Ribulose 5-phosphate
type: SmallMolecule
entity reference: D-Ribulose 5-phosphate

Reference/HMDB HMDB0000868
type: UnificationXref
id: HMDB0000868
db: HMDB

Reference/UniProt P0AG07
type: UnificationXref
id: P0AG07
db: UniProt

Reference/BioCyc XYLULOSE-5-PHOSPHATE
type: UnificationXref
id: XYLULOSE-5-PHOSPHATE
db: BioCyc

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

Transketolase 2
type: ProteinReference
xref: Reference/UniProt P33570

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Compound/PW C000479/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Ribulose 5-phosphate
stoichiometric coefficient: 1.0

Protein/6466/Stoichiometry/2.0
type: Stoichiometry
physical entity: Transketolase 1
stoichiometric coefficient: 2.0

Xylulose 5-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000868
xref: Reference/KEGG Compound C00231
xref: Reference/BioCyc XYLULOSE-5-PHOSPHATE
xref: Reference/PubChem-compound 439190
xref: Reference/CAS 60802-29-1
xref: Reference/ChEBI CHEBI 16332
xref: Reference/ChemSpider 388330
chemical formula: C5H11O8P
molecular weight: 230.01915
structure: ChemicalStructure/PW C000691

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChemSpider 109096
type: UnificationXref
id: 109096
db: ChemSpider

Reference/PathWhiz PW000909
type: UnificationXref
id: PW000909
db: PathWhiz

ChemicalStructure/PW C002021
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000881
type: ChemicalStructure
structure format: SMILES

Reference/CAS 4300-28-1
type: UnificationXref
id: 4300-28-1
db: CAS