Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/PubChem-compound 923
type: UnificationXref
id: 923
db: PubChem-compound

Oxalacetic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000223
xref: Reference/CAS 328-42-7
xref: Reference/ChEBI CHEBI 30744
xref: Reference/BioCyc OXALACETIC ACID
xref: Reference/ChemSpider 945
xref: Reference/PubChem-compound 970
xref: Reference/KEGG Compound C00036
chemical formula: C4H4O5
molecular weight: 132.00587
structure: ChemicalStructure/PW C000148

L-Glutamine
type: SmallMolecule
cellular location: Inner Membrane
entity reference: L-Glutamine

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

ReactionCoupledTransportCatalysis10882
type: Catalysis
controller: Unknown
controlled: ReactionCoupledTransport10820
control type: ACTIVATION

Reference/ChEBI CHEBI 16134
type: UnificationXref
id: CHEBI:16134
db: ChEBI

ReactionCoupledTransportCatalysis10886
type: Catalysis
controller: glutamine ABC transporter
controlled: ReactionCoupledTransport10824
control type: ACTIVATION

direct_interaction
type: InteractionVocabulary

Reference/CAS 110-17-8
type: UnificationXref
id: 110-17-8
db: CAS

Reference/PubChem-compound 21883788
type: UnificationXref
id: 21883788
db: PubChem-compound

Aminotransferase
type: ProteinReference
organism: Methylococcus capsulatus

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Ammonia
type: SmallMoleculeReference
xref: Reference/BioCyc AMMONIA
xref: Reference/CAS 7664-41-7
xref: Reference/HMDB HMDB0000051
xref: Reference/PubChem-compound 222
xref: Reference/KEGG Compound C00014
xref: Reference/ChEBI CHEBI 16134
xref: Reference/ChemSpider 217
chemical formula: H3N
molecular weight: 17.026548
structure: ChemicalStructure/PW C000035

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C000500 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Pyrimidine Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway593721
pathway component: SubPathwayInteraction593721
xref: Reference/PathWhiz PW000942
xref: Reference/SMPDB SMP0000959
name: SubPathway

Formate-dependent phosphoribosylglycinamide formyltransferase
type: Protein
entity reference: Formate-dependent phosphoribosylglycinamide formyltransferase

Fumarate hydratase class II
type: Protein
entity reference: Fumarate hydratase class II

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/BioCyc OXALACETIC ACID
type: UnificationXref
id: OXALACETIC_ACID
db: BioCyc

ChemicalStructure/PW C000458
type: ChemicalStructure
structure format: SMILES
structure data: [Na+]

Compound/PW C000143 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/PubChem-compound 5961
type: UnificationXref
id: 5961
db: PubChem-compound

Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Reference/HMDB HMDB0000661
type: UnificationXref
id: HMDB0000661
db: HMDB

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/CAS 328-42-7
type: UnificationXref
id: 328-42-7
db: CAS

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Succinic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Succinic acid

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Compound/PW C000035/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonia
stoichiometric coefficient: 1.0

Methylococcus capsulatus
type: BioSource
xref: Reference/TAXONOMY 414

ReactionCoupledTransportCatalysis39088
type: Catalysis
controller: glutamine ABC transporter
controlled: ReactionCoupledTransport39026
control type: ACTIVATION

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/ChemSpider 5746
type: UnificationXref
id: 5746
db: ChemSpider

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

aspartate ammonia-lyase
type: Complex
component stoichiometry: Protein/98049/Stoichiometry/4.0
component: Fumarate hydratase class II

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Protein/98049/Stoichiometry/4.0
type: Stoichiometry
physical entity: Fumarate hydratase class II
stoichiometric coefficient: 4.0

glutaminase
type: Complex
component: Formate-dependent phosphoribosylglycinamide formyltransferase
component: Unknown

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/UniProt Q9ADT0
type: UnificationXref
id: Q9ADT0
db: UniProt

Ammonia
type: SmallMolecule
entity reference: Ammonia

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Compound/PW C000088 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Glutaric acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Glutaric acid
name: SubPathwayOutput

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 945
type: UnificationXref
id: 945
db: ChemSpider

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reference/SMPDB SMP0000795
type: UnificationXref
id: SMP0000795
db: SMPDB

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/PathWhiz PW000942
type: UnificationXref
id: PW000942
db: PathWhiz

Reference/UniProt Q608E9
type: UnificationXref
id: Q608E9
db: UniProt

Reference/PubChem-compound 23724570
type: UnificationXref
id: 23724570
db: PubChem-compound

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/CAS 5105-96-4
type: UnificationXref
id: 5105-96-4
db: CAS

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Ammonium
type: SmallMolecule
entity reference: Ammonium

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C000146 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Fumaric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Fumaric acid

L-Glutamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000641
xref: Reference/ChEBI CHEBI 18050
xref: Reference/ChemSpider 5746
xref: Reference/BioCyc GLN
xref: Reference/KEGG Compound C00064
xref: Reference/PubChem-compound 5961
xref: Reference/CAS 56-85-9
chemical formula: C5H10N2O3
molecular weight: 146.06914
structure: ChemicalStructure/PW C000500

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Reference/ChemSpider 217
type: UnificationXref
id: 217
db: ChemSpider

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/ChEBI CHEBI 49260
type: UnificationXref
id: CHEBI:49260
db: ChEBI

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Compound/PW C000500 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/PathWhiz PW000779
type: UnificationXref
id: PW000779
db: PathWhiz

glutamate synthase
type: Complex
cellular location: Cytosol
component: Formylmethanofurane dehydrogenase-like protein
component: Glutamate synthase [NADPH] small chain

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Compound/PW C000095 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 2.0

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Unknown
type: Protein
cellular location: Inner Membrane
entity reference: Unknown

Reference/PathWhiz PW000772
type: UnificationXref
id: PW000772
db: PathWhiz

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Compound/PW C000500/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamine
stoichiometric coefficient: 1.0

Formylmethanofurane dehydrogenase-like protein
type: Protein
cellular location: Cytosol
entity reference: Formylmethanofurane dehydrogenase-like protein

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

ReactionCatalysis1568003
type: Catalysis
controller: Unknown
controlled: Reaction1520571
control type: ACTIVATION

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00122
type: UnificationXref
id: C00122
db: KEGG Compound

ReactionCatalysis1568001
type: Catalysis
controller: glutamate synthase
controlled: Reaction1520569
control type: ACTIVATION

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

4-(Glutamylamino) butanoate
type: SmallMolecule
entity reference: 4-(Glutamylamino) butanoate

Reference/KEGG Compound C01330
type: UnificationXref
id: C01330
db: KEGG Compound

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/BioCyc CPD-9000
type: UnificationXref
id: CPD-9000
db: BioCyc

Reference/KEGG Compound C00489
type: UnificationXref
id: C00489
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Sulfate transporter family protein
type: Protein
entity reference: Sulfate transporter family protein

NADPH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADPH

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Compound/PW C000148 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxalacetic acid
stoichiometric coefficient: 1.0

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Glutaric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000661
xref: Reference/PubChem-compound 743
xref: Reference/CAS 110-94-1
xref: Reference/ChEBI CHEBI 17859
xref: Reference/KEGG Compound C00489
xref: Reference/ChemSpider 723
chemical formula: C5H8O4
molecular weight: 132.04225
structure: ChemicalStructure/PW C000518

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Reference/HMDB HMDB0000223
type: UnificationXref
id: HMDB0000223
db: HMDB

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000588
type: UnificationXref
id: HMDB0000588
db: HMDB

Fumaric acid
type: SmallMolecule
entity reference: Fumaric acid

Compound/PW C007718/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-(Glutamylamino) butanoate
stoichiometric coefficient: 1.0

Reference/UniProt Q606K7
type: UnificationXref
id: Q606K7
db: UniProt

Reference/BioCyc GLN
type: UnificationXref
id: GLN
db: BioCyc

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 7664-41-7
type: UnificationXref
id: 7664-41-7
db: CAS

Fumaric acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000134
xref: Reference/ChemSpider 10197150
xref: Reference/CAS 110-17-8
xref: Reference/PubChem-compound 21883788
xref: Reference/KEGG Compound C00122
xref: Reference/BioCyc FUM
xref: Reference/ChEBI CHEBI 18012
chemical formula: C4H4O4
molecular weight: 116.010956
structure: ChemicalStructure/PW C000088

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C000123/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

TransportCatalysis69293
type: Catalysis
controller: dicarboxylate transporter
controlled: Transport92775
control type: ACTIVATION

Glutaric acid
type: SmallMolecule
entity reference: Glutaric acid

Oxoglutaric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Oxoglutaric acid
name: SubPathwayInput

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Compound/PW C000174 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

Reference/CAS 110-94-1
type: UnificationXref
id: 110-94-1
db: CAS

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway593720
pathway component: SubPathwayInteraction593720
xref: Reference/SMPDB SMP0000802
xref: Reference/PathWhiz PW000779
name: SubPathway

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Reference/PubChem-compound 222
type: UnificationXref
id: 222
db: PubChem-compound

Reference/KEGG Compound C00014
type: UnificationXref
id: C00014
db: KEGG Compound

TransportCatalysis69292
type: Catalysis
controller: Sulfate transporter family protein
controlled: Transport92774
control type: ACTIVATION

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

TransportCatalysis69291
type: Catalysis
controller: C4 dicarboxylate/orotate:H(+) symporter
controlled: Transport92773
control type: ACTIVATION

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Compound/PW C000095 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

L-Glutamine
type: SmallMolecule
entity reference: L-Glutamine

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

ReactionCatalysis782538
type: Catalysis
controller: aspartate transaminase
controlled: Reaction779659
control type: ACTIVATION

L-Glutamic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamic acid

Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

TransportCatalysis38459
type: Catalysis
controller: C4 dicarboxylate/orotate:H(+) symporter
controlled: Transport57522
control type: ACTIVATION

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Reference/PathWhiz PW558832
type: UnificationXref
id: PW558832
db: PathWhiz

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

TransportCatalysis38460
type: Catalysis
controller: Transporter
controlled: Transport57523
control type: ACTIVATION

Unknown
type: ProteinReference

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

NADP
type: SmallMolecule
cellular location: Cytosol
entity reference: NADP

Reference/ChEBI CHEBI 29101
type: UnificationXref
id: CHEBI:29101
db: ChEBI

Reference/SMPDB SMP0000802
type: UnificationXref
id: SMP0000802
db: SMPDB

Aminotransferase
type: Protein
cellular location: Cytosol
entity reference: Aminotransferase

Adenosine triphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine triphosphate

ReactionCoupledTransport39026
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000500 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: Adenosine triphosphate
right: L-Glutamine
right: Hydrogen Ion
spontaneous: false
left: Water
left: Adenosine triphosphate
left: L-Glutamine
name: Adenosine triphosphate + L-Glutamine + Water ? Adenosine triphosphate + Hydrogen Ion + L-Glutamine + Phosphate

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/KEGG Compound C00036
type: UnificationXref
id: C00036
db: KEGG Compound

Reference/ChemSpider 899
type: UnificationXref
id: 899
db: ChemSpider

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Reference/HMDB HMDB0000134
type: UnificationXref
id: HMDB0000134
db: HMDB

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Oxalacetic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Oxalacetic acid

Protein/51793 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Aminotransferase
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 17859
type: UnificationXref
id: CHEBI:17859
db: ChEBI

Uncharacterized protein
type: ProteinReference

Reference/KEGG Compound C15767
type: UnificationXref
id: C15767
db: KEGG Compound

Probable membrane transporter protein
type: ProteinReference

C4 dicarboxylate/orotate:H(+) symporter
type: ProteinReference

Lysine Degradation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway593722
pathway component: SubPathwayInteraction593722
xref: Reference/PathWhiz PW000772
xref: Reference/SMPDB SMP0000795
name: SubPathway

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Putative membrane protein
type: ProteinReference
xref: Reference/UniProt Q606T8

ReactionCatalysis1567998
type: Catalysis
controller: aspartate ammonia-lyase
controlled: Reaction1520566
control type: ACTIVATION

Reaction779659
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000148 Cytosol/Stoichiometry/1.0
right: L-Aspartic acid
right: Oxoglutaric acid
spontaneous: false
left: Oxalacetic acid
left: L-Glutamic acid
name: L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis1567999
type: Catalysis
controller: Unknown
controlled: Reaction1520567
control type: ACTIVATION

Phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Phosphate

ReactionCatalysis1567996
type: Catalysis
controller: glutaminase
controlled: 3.5.1.2
control type: ACTIVATION

ReactionCatalysis1567997
type: Catalysis
controller: Unknown
controlled: Reaction1520565
control type: ACTIVATION

Protein/27663 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Transport57523
type: Transport
participant stoichiometry: Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Cytosol/Stoichiometry/1.0
right: Sodium
right: L-Glutamic acid
spontaneous: false
left: Sodium
left: L-Glutamic acid
name: L-Glutamic acid (→), Sodium (→) Transport: Methylococcus capsulatus, Periplasmic Space to Methylococcus capsulatus, Cytosol
conversion direction: LEFT_TO_RIGHT

Transport57522
type: Transport
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: L-Glutamic acid
spontaneous: false
left: Hydrogen Ion
left: L-Glutamic acid
name: Hydrogen Ion (→), L-Glutamic acid (→) Transport: Methylococcus capsulatus, Periplasmic Space to Methylococcus capsulatus, Cytosol
conversion direction: LEFT_TO_RIGHT

Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Reference/CAS 56-85-9
type: UnificationXref
id: 56-85-9
db: CAS

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Transport92775
type: Transport
participant stoichiometry: Compound/PW C000088 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000174 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088 Periplasmic Space/Stoichiometry/1.0
right: Fumaric acid
right: Succinic acid
spontaneous: false
left: Succinic acid
left: Fumaric acid
name: Fumaric acid (→), Succinic acid (←) Transport: Methylococcus capsulatus, Periplasmic Space to Methylococcus capsulatus, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

Compound/PW C000134 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Transport92774
type: Transport
participant stoichiometry: Compound/PW C000088 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088 Periplasmic Space/Stoichiometry/1.0
right: Fumaric acid
spontaneous: false
left: Fumaric acid
name: Fumaric acid (→) Transport: Methylococcus capsulatus, Periplasmic Space to Methylococcus capsulatus, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/TAXONOMY 414
type: UnificationXref
id: 414
db: TAXONOMY

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Transport92773
type: Transport
participant stoichiometry: Compound/PW C000088 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088 Periplasmic Space/Stoichiometry/1.0
right: Fumaric acid
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: Fumaric acid
name: Fumaric acid (→), Hydrogen Ion (→) Transport: Methylococcus capsulatus, Periplasmic Space to Methylococcus capsulatus, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/CAS 17341-25-2
type: UnificationXref
id: 17341-25-2
db: CAS

Reference/SMPDB SMP0530198
type: UnificationXref
id: SMP0530198
db: SMPDB

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

ReactionCoupledTransport10820
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: L-Glutamic acid
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Water
left: Adenosine triphosphate
left: L-Glutamic acid
name: Adenosine triphosphate + L-Glutamic acid + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamic acid + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 10197150
type: UnificationXref
id: 10197150
db: ChemSpider

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

ReactionCoupledTransport10824
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000500 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
right: Phosphate
right: L-Glutamine
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Water
left: Adenosine triphosphate
left: L-Glutamine
name: Adenosine triphosphate + L-Glutamine + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc FUM
type: UnificationXref
id: FUM
db: BioCyc

4-(Glutamylamino) butanoate
type: SmallMoleculeReference
xref: Reference/CAS 5105-96-4
xref: Reference/ChEBI CHEBI 49260
xref: Reference/ChemSpider 21865667
xref: Reference/HMDB HMDB0012161
xref: Reference/BioCyc CPD-9000
xref: Reference/KEGG Compound C15767
xref: Reference/PubChem-compound 23724570
chemical formula: C9H16N2O5
molecular weight: 232.10593
structure: ChemicalStructure/PW C007718

Reaction1520571
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Phosphate
right: L-Glutamine
right: Adenosine diphosphate
right: Hydrogen Ion
spontaneous: false
left: Adenosine triphosphate
left: Ammonium
left: L-Glutamic acid
name: Adenosine triphosphate + Ammonium + L-Glutamic acid → Adenosine diphosphate + Hydrogen Ion + L-Glutamine + Phosphate
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000148
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CC(=O)C(O)=O

glutamine ABC transporter
type: Complex
component stoichiometry: Protein/27663 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown

Interaction8811
type: MolecularInteraction
interaction type: direct_interaction
name: Glutaric acid inhibits glutamate decarboxylase
participant: Glutaric acid
participant: Unknown

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChEBI CHEBI 18012
type: UnificationXref
id: CHEBI:18012
db: ChEBI

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/BioCyc AMMONIA
type: UnificationXref
id: AMMONIA
db: BioCyc

ChemicalStructure/PW C000035
type: ChemicalStructure
structure format: SMILES
structure data: N

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reaction1520566
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000088/Stoichiometry/1.0
right: Ammonium
right: Fumaric acid
spontaneous: false
left: L-Aspartic acid
name: L-Aspartic acid → Ammonium + Fumaric acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Reaction1520567
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007718/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Carbon dioxide
right: 4-(Glutamylamino) butanoate
spontaneous: false
left: L-Glutamic acid
left: Hydrogen Ion
name: Hydrogen Ion + L-Glutamic acid → 4-(Glutamylamino) butanoate + Carbon dioxide
conversion direction: LEFT_TO_RIGHT

Reaction1520569
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095 Cytosol/Stoichiometry/2.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143 Cytosol/Stoichiometry/1.0
right: L-Glutamic acid
right: NADP
spontaneous: false
left: L-Glutamine
left: Oxoglutaric acid
left: Hydrogen Ion
left: NADPH
name: Hydrogen Ion + L-Glutamine + NADPH + Oxoglutaric acid → 2 L-Glutamic acid + NADP
conversion direction: LEFT_TO_RIGHT

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

3.5.1.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000500/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000035/Stoichiometry/1.0
right: L-Glutamic acid
right: Ammonia
spontaneous: false
EC number: 3.5.1.2
left: Water
left: L-Glutamine
name: L-Glutamine + Water → Ammonia + L-Glutamic acid
conversion direction: LEFT_TO_RIGHT

Reaction1520565
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: L-Glutamic acid
right: Water
right: NADP
spontaneous: false
left: Ammonium
left: Oxoglutaric acid
left: Hydrogen Ion
left: NADPH
name: Ammonium + Hydrogen Ion + NADPH + Oxoglutaric acid → L-Glutamic acid + NADP + Water
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C000095 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Compound/PW C000174 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00064
type: UnificationXref
id: C00064
db: KEGG Compound

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Glutamate synthase [NADPH] small chain
type: ProteinReference
organism: Methylococcus capsulatus

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

L-Glutamic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Glutamic acid

Reference/SMPDB SMP0000959
type: UnificationXref
id: SMP0000959
db: SMPDB

Transporter
type: ProteinReference

Transporter
type: Protein
entity reference: Transporter

Succinic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Succinic acid

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

dicarboxylate transporter
type: Complex
component: Uncharacterized protein
component: Putative membrane protein
component: Probable membrane transporter protein

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Sodium
type: SmallMolecule
cellular location: Cytosol
entity reference: Sodium

ChemicalStructure/PW C007718
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(=O)NCCCC(O)=O)C(O)=O

Compound/PW C000458 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

L-Glutamate Metabolism
type: Pathway
pathway order: PathwayTransport/7566472
pathway order: PathwaySubPathway/593721
pathway order: PathwayTransport/7566471
pathway order: PathwaySubPathway/593722
pathway order: PathwayTransport/7566476
pathway order: PathwayInteraction/8811
pathway order: PathwayTransport/7566474
pathway order: PathwaySubPathway/593720
pathway order: PathwayTransport/7566477
pathway order: PathwayEnzymeReaction/7566459
pathway order: PathwayEnzymeReaction/7566456
pathway order: PathwayEnzymeReaction/7566467
pathway order: PathwayEnzymeReaction/7566457
pathway order: PathwayEnzymeReaction/7566468
pathway order: PathwayEnzymeReaction/7566463
pathway order: PathwayEnzymeReaction/7566454
pathway order: PathwayEnzymeReaction/7566465
pathway order: PathwayEnzymeReaction/7566470
pathway order: PathwayEnzymeReaction/7566461
pathway component: ReactionCoupledTransport10820
pathway component: TransportCatalysis69293
pathway component: ReactionCoupledTransportCatalysis39088
pathway component: ReactionCoupledTransport10824
pathway component: TCA Cycle
pathway component: ReactionCoupledTransport39026
pathway component: Reaction1520571
pathway component: ReactionCoupledTransportCatalysis10882
pathway component: Interaction8811
pathway component: ReactionCoupledTransportCatalysis10886
pathway component: TransportCatalysis69292
pathway component: TransportCatalysis69291
pathway component: Lysine Degradation
pathway component: Reaction1520566
pathway component: ReactionCatalysis1567998
pathway component: Reaction779659
pathway component: Reaction1520567
pathway component: ReactionCatalysis1567999
pathway component: ReactionCatalysis1567996
pathway component: ReactionCatalysis1567997
pathway component: Reaction1520569
pathway component: Pyrimidine Metabolism
pathway component: 3.5.1.2
pathway component: ReactionCatalysis1568003
pathway component: Transport57523
pathway component: Reaction1520565
pathway component: Transport57522
pathway component: ReactionCatalysis1568001
pathway component: ReactionCatalysis782538
pathway component: TransportCatalysis38459
pathway component: Transport92775
pathway component: Transport92774
pathway component: TransportCatalysis38460
pathway component: Transport92773
xref: Reference/SMPDB SMP0530198
xref: Reference/PathWhiz PW558832
organism: Methylococcus capsulatus

Formate-dependent phosphoribosylglycinamide formyltransferase
type: ProteinReference
xref: Reference/UniProt Q606K7

Fumarate hydratase class II
type: ProteinReference
xref: Reference/UniProt Q608E9

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Compound/PW C000095 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000051
type: UnificationXref
id: HMDB0000051
db: HMDB

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

SubPathwayInteraction593720
type: Interaction
name: SubPathwayReaction
name: SubPathway593720Reaction
participant: Oxoglutaric acid

SubPathwayInteraction593721
type: Interaction
name: SubPathway593721Reaction
name: SubPathwayReaction
participant: L-Glutamine

SubPathwayInteraction593722
type: Interaction
name: SubPathway593722Reaction
name: SubPathwayReaction
participant: Glutaric acid

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Sodium
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Sodium

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/HMDB HMDB0012161
type: UnificationXref
id: HMDB0012161
db: HMDB

aspartate transaminase
type: Complex
component stoichiometry: Protein/51793 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Aminotransferase

C4 dicarboxylate/orotate:H(+) symporter
type: Protein
entity reference: C4 dicarboxylate/orotate:H(+) symporter

Formylmethanofurane dehydrogenase-like protein
type: ProteinReference
xref: Reference/UniProt Q9ADT0
organism: Methylococcus capsulatus

Reference/ChemSpider 723
type: UnificationXref
id: 723
db: ChemSpider

Reference/UniProt Q606T8
type: UnificationXref
id: Q606T8
db: UniProt

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

L-Aspartic acid
type: SmallMolecule
entity reference: L-Aspartic acid

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Uncharacterized protein
type: Protein
entity reference: Uncharacterized protein

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Putative membrane protein
type: Protein
entity reference: Putative membrane protein

Reference/ChEBI CHEBI 30744
type: UnificationXref
id: CHEBI:30744
db: ChEBI

Probable membrane transporter protein
type: Protein
entity reference: Probable membrane transporter protein

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

Reference/PubChem-compound 743
type: UnificationXref
id: 743
db: PubChem-compound

L-Glutamine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Glutamine
name: SubPathwayInput

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

Sulfate transporter family protein
type: ProteinReference

ChemicalStructure/PW C000500
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(N)=O)C(O)=O

Fumaric acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Fumaric acid

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

L-Aspartic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Aspartic acid

Reference/ChEBI CHEBI 18050
type: UnificationXref
id: CHEBI:18050
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

Ammonium
type: SmallMolecule
cellular location: Cytosol
entity reference: Ammonium

Unknown
type: Protein
entity reference: Unknown

Compound/PW C000088 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Sodium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000588
xref: Reference/PubChem-compound 923
xref: Reference/KEGG Compound C01330
xref: Reference/ChEBI CHEBI 29101
xref: Reference/ChemSpider 899
xref: Reference/CAS 17341-25-2
chemical formula: Na
molecular weight: 22.989769
structure: ChemicalStructure/PW C000458

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

L-Glutamic acid
type: SmallMolecule
cellular location: Inner Membrane
entity reference: L-Glutamic acid

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Reference/ChemSpider 21865667
type: UnificationXref
id: 21865667
db: ChemSpider

ChemicalStructure/PW C000518
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCCC(O)=O

Compound/PW C022608 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 970
type: UnificationXref
id: 970
db: PubChem-compound

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000088
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)\C=C\C(O)=O

Reference/HMDB HMDB0000641
type: UnificationXref
id: HMDB0000641
db: HMDB

Compound/PW C000123 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Glutamate synthase [NADPH] small chain
type: Protein
cellular location: Cytosol
entity reference: Glutamate synthase [NADPH] small chain

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C000088/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fumaric acid
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine diphosphate

Compound/PW C001104 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0