Compound/PW C000170 Cytoplasm/Stoichiometry/6.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 6.0

Compound/PW C000120 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 3.0

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Phenylalanine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway369051
pathway component: SubPathwayInteraction369051
xref: Reference/PathWhiz PW000807
xref: Reference/SMPDB SMP0000827
name: SubPathway

Reference/PubChem-compound 923
type: UnificationXref
id: 923
db: PubChem-compound

Tyrosine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway369053
pathway component: SubPathwayInteraction369053
xref: Reference/SMPDB SMP0000826
xref: Reference/PathWhiz PW000806
name: SubPathway

3-oxoacyl-[acyl-carrier-protein] reductase
type: ProteinReference
xref: Reference/UniProt C9LG00
organism: Alloprevotella tannerae ATCC 51259

Reference/UniProt C9LJW8
type: UnificationXref
id: C9LJW8
db: UniProt

Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein
type: Protein
entity reference: Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

L-Serine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Serine

Secretion system C-terminal sorting domain-containing protein
type: Protein
entity reference: Secretion system C-terminal sorting domain-containing protein

Chorismate
type: SmallMolecule
cellular location: Cytosol
entity reference: Chorismate
name: SubPathwayOutput

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

Reference/PubChem-compound 29936
type: UnificationXref
id: 29936
db: PubChem-compound

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

enterobactin synthase
type: Complex
component stoichiometry: Protein/35266 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: 4'-phosphopantetheinyl transferase family protein
component: AMP-binding enzyme
component: SsuA/THI5-like domain-containing protein

ABC transporter, ATP-binding protein
type: Protein
cellular location: Inner Membrane
entity reference: ABC transporter, ATP-binding protein

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Unknown
type: Protein
entity reference: Unknown

isochorismate
type: SmallMolecule
entity reference: isochorismate

Reference/UniProt C9LI36
type: UnificationXref
id: C9LI36
db: UniProt

Biosynthesis of Siderophore Group Nonribosomal Peptides
type: Pathway
pathway order: PathwayEnzymeReaction/5470074
pathway order: PathwaySubPathway/369051
pathway order: PathwayEnzymeReaction/5470073
pathway order: PathwayEnzymeReaction/5470072
pathway order: PathwaySubPathway/369053
pathway order: PathwaySubPathway/369052
pathway order: PathwayTransport/5470083
pathway order: PathwayTransport/5470082
pathway order: PathwayEnzymeReaction/5470079
pathway order: PathwayEnzymeReaction/5470078
pathway order: PathwayEnzymeReaction/5470077
pathway order: PathwayEnzymeReaction/5470076
pathway order: PathwayTransport/5470081
pathway order: PathwayEnzymeReaction/5470075
pathway order: PathwayTransport/5470080
pathway component: Phenylalanine Biosynthesis
pathway component: Tyrosine Biosynthesis
pathway component: Transport35047
pathway component: Transport35048
pathway component: Transport35045
pathway component: Transport35046
pathway component: ReactionCatalysis555638
pathway component: ReactionCatalysis555639
pathway component: Reaction561973
pathway component: 1.3.1.28
pathway component: Reaction561975
pathway component: 6.3.2.14
pathway component: 5.4.4.2
pathway component: Tryptophan Metabolism
pathway component: TransportCatalysis18596
pathway component: Reaction3390
pathway component: TransportCatalysis18597
pathway component: ReactionCoupledTransport4440
pathway component: ReactionCoupledTransportCatalysis4502
pathway component: TransportCatalysis18598
pathway component: TransportCatalysis18599
pathway component: ReactionCatalysis555641
pathway component: ReactionCatalysis555640
pathway component: ReactionCatalysis555643
pathway component: ReactionCatalysis555642
xref: Reference/PathWhiz PW684247
xref: Reference/SMPDB SMP0643902
organism: Alloprevotella tannerae ATCC 51259

Reference/ChEBI CHEBI 17115
type: UnificationXref
id: CHEBI:17115
db: ChEBI

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

EntS-TolC Enterobactin Efflux Transport System
type: Complex
component stoichiometry: Protein/35267/Stoichiometry/3.0
component: L-fucose:H+ symporter permease
component: Outer membrane efflux protein

Tryptophan Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway369052
pathway component: SubPathwayInteraction369052
xref: Reference/SMPDB SMP0000835
xref: Reference/PathWhiz PW000815
name: SubPathway

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

ChemicalStructure/PW C000458
type: ChemicalStructure
structure format: SMILES
structure data: [Na+]

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Ferric enterobactin
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Ferric enterobactin

Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/3.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 3.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 5572
type: UnificationXref
id: CHEBI:5572
db: ChEBI

Compound/PW C040770 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
stoichiometric coefficient: 1.0

Compound/PW C040770 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
stoichiometric coefficient: 1.0

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

2,3-Dihydroxybenzoic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 2,3-Dihydroxybenzoic acid

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Compound/PW C040792 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2,3-Dihydroxybenzoic acid
stoichiometric coefficient: 1.0

ferric enterobactin ABC transporter
type: Complex
component stoichiometry: Protein/35273 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Iron chelate uptake ABC transporter, FeCT family, permease protein
component: Uncharacterized protein
component: ABC transporter, ATP-binding protein

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/UniProt C9LG00
type: UnificationXref
id: C9LG00
db: UniProt

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

ferric enterobactin outer membrane transport complex
type: Complex
component: Transporter, MotA/TolQ/ExbB proton channel family protein
component: Transport energizing protein, ExbD/TolR family
component: TonB-dependent receptor
component: Penicillin-binding protein, transpeptidase domain protein

isochorismate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 29780
xref: Reference/KEGG Compound C00885
chemical formula: C10H8O6
molecular weight: 224.03319
structure: ChemicalStructure/PW C040741

Reference/ChEBI CHEBI 15941
type: UnificationXref
id: CHEBI:15941
db: ChEBI

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C000544
type: ChemicalStructure
structure format: SMILES
structure data: [Fe++]

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/BioCyc Ferric-Hydroxamate-Complexes
type: UnificationXref
id: Ferric-Hydroxamate-Complexes
db: BioCyc

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/UniProt C9LD97
type: UnificationXref
id: C9LD97
db: UniProt

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Reference/ChemSpider 5736
type: UnificationXref
id: 5736
db: ChemSpider

Reference/ChEBI CHEBI 17455
type: UnificationXref
id: CHEBI:17455
db: ChEBI

Adenosine monophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine monophosphate

Reference/UniProt C9LFL0
type: UnificationXref
id: C9LFL0
db: UniProt

Compound/PW C041655 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ferric enterobactin
stoichiometric coefficient: 1.0

Reference/PubChem-compound 440956
type: UnificationXref
id: 440956
db: PubChem-compound

Reference/PubChem-compound 25244759
type: UnificationXref
id: 25244759
db: PubChem-compound

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/BioCyc SER
type: UnificationXref
id: SER
db: BioCyc

ReactionCoupledTransportCatalysis4502
type: Catalysis
controller: ferric enterobactin ABC transporter
controlled: ReactionCoupledTransport4440
control type: ACTIVATION

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Reference/ChemSpider 27815
type: UnificationXref
id: 27815
db: ChemSpider

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/ChEBI CHEBI 29780
type: UnificationXref
id: CHEBI:29780
db: ChEBI

SsuA/THI5-like domain-containing protein
type: ProteinReference
xref: Reference/UniProt C9LFZ4

Reference/UniProt C9LDG0
type: UnificationXref
id: C9LDG0
db: UniProt

Ferric enterobactin
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Ferric enterobactin

(2,3-Dihydroxybenzoyl)adenylic acid
type: SmallMolecule
entity reference: (2,3-Dihydroxybenzoyl)adenylic acid

Penicillin-binding protein, transpeptidase domain protein
type: ProteinReference
xref: Reference/UniProt C9LJW8

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

4'-phosphopantetheinyl transferase family protein
type: ProteinReference
xref: Reference/UniProt C9LG14
organism: Alloprevotella tannerae ATCC 51259

Outer membrane efflux protein
type: ProteinReference
xref: Reference/UniProt C9LI87

Ferric enterobactin
type: SmallMolecule
cellular location: Extracellular Space
entity reference: Ferric enterobactin

Compound/PW C040793 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: enterobactin
stoichiometric coefficient: 1.0

Reference/PubChem-compound 27284
type: UnificationXref
id: 27284
db: PubChem-compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

2,3-Dihydroxybenzoylserine
type: SmallMolecule
entity reference: 2,3-Dihydroxybenzoylserine

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000120 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/UniProt C9LCV0
type: UnificationXref
id: C9LCV0
db: UniProt

Fe3+
type: SmallMolecule
entity reference: Fe3+

SubPathwayInteraction369053
type: Interaction
name: SubPathway369053Reaction
name: SubPathwayReaction
participant: Chorismate

SubPathwayInteraction369052
type: Interaction
name: SubPathway369052Reaction
name: SubPathwayReaction
participant: Chorismate

SubPathwayInteraction369051
type: Interaction
name: SubPathway369051Reaction
name: SubPathwayReaction
participant: Chorismate

ChemicalStructure/PW C040792
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C1=C([O-])C(O)=CC=C1

Hydrogen Ion
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Hydrogen Ion

Reference/HMDB HMDB0000692
type: UnificationXref
id: HMDB0000692
db: HMDB

Reference/TAXONOMY 626522
type: UnificationXref
id: 626522
db: TAXONOMY

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

ChemicalStructure/PW C040793
type: ChemicalStructure
structure format: SMILES

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

enterobactin
type: SmallMolecule
cellular location: Cytoplasm
entity reference: enterobactin

Reference/KEGG Compound C01330
type: UnificationXref
id: C01330
db: KEGG Compound

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/UniProt C9LGL5
type: UnificationXref
id: C9LGL5
db: UniProt

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/KEGG Compound C04171
type: UnificationXref
id: C04171
db: KEGG Compound

Uncharacterized protein
type: Protein
cellular location: Inner Membrane
entity reference: Uncharacterized protein

Unknown
type: ProteinReference

Reference/HMDB HMDB0000588
type: UnificationXref
id: HMDB0000588
db: HMDB

L-fucose:H+ symporter permease
type: ProteinReference
xref: Reference/UniProt C9LD97

Compound/PW C040793 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: enterobactin
stoichiometric coefficient: 1.0

Reference/UniProt C9LCU9
type: UnificationXref
id: C9LCU9
db: UniProt

ChemicalStructure/PW C041655
type: ChemicalStructure
structure format: SMILES

Compound/PW C000032 Cytoplasm/Stoichiometry/6.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 6.0

Unknown
type: Protein
cellular location: Cytoplasm
entity reference: Unknown

Fe2+
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Fe2+

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/UniProt C9LFI8
type: UnificationXref
id: C9LFI8
db: UniProt

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/PubChem-compound 5951
type: UnificationXref
id: 5951
db: PubChem-compound

Compound/PW C040792 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: 2,3-Dihydroxybenzoic acid
stoichiometric coefficient: 3.0

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Extracellular Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005615

Compound/PW C040793 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: enterobactin
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Compound/PW C041655 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ferric enterobactin
stoichiometric coefficient: 1.0

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Transport35047
type: Transport
participant stoichiometry: Compound/PW C041655 Extracellular Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041655 Periplasmic Space/Stoichiometry/1.0
right: Ferric enterobactin
spontaneous: false
left: Ferric enterobactin
name: Ferric enterobactin (→) Transport: Alloprevotella tannerae ATCC 51259, Extracellular Space to Alloprevotella tannerae ATCC 51259, Periplasmic Space
conversion direction: LEFT_TO_RIGHT

Transport35048
type: Transport
participant stoichiometry: Compound/PW C000120 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000458 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000120 Periplasmic Space/Stoichiometry/1.0
right: Sodium
right: L-Serine
spontaneous: false
left: Sodium
left: L-Serine
name: L-Serine (→), Sodium (→) Transport: Alloprevotella tannerae ATCC 51259, Periplasmic Space to Alloprevotella tannerae ATCC 51259, Cytosol
conversion direction: LEFT_TO_RIGHT

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Transport35045
type: Transport
participant stoichiometry: Compound/PW C040793 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040793 Cytosol/Stoichiometry/1.0
right: enterobactin
spontaneous: false
left: enterobactin
name: enterobactin (→) Transport: Alloprevotella tannerae ATCC 51259, Cytosol to Alloprevotella tannerae ATCC 51259, Periplasmic Space
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Transport35046
type: Transport
participant stoichiometry: Compound/PW C040793 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040793 Extracellular Space/Stoichiometry/1.0
right: enterobactin
spontaneous: false
left: enterobactin
name: enterobactin (→) Transport: Alloprevotella tannerae ATCC 51259, Periplasmic Space to Alloprevotella tannerae ATCC 51259, Extracellular Space
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Reference/UniProt C9LFZ4
type: UnificationXref
id: C9LFZ4
db: UniProt

Pyruvic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyruvic acid

Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein
type: ProteinReference
xref: Reference/UniProt C9LEN7

Secretion system C-terminal sorting domain-containing protein
type: ProteinReference
xref: Reference/UniProt C9LFI8

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Uncharacterized protein
type: ProteinReference
xref: Reference/UniProt C9LFL0
organism: Alloprevotella tannerae ATCC 51259

Iron chelate uptake ABC transporter, FeCT family, permease protein
type: ProteinReference
xref: Reference/UniProt C9LKL3
organism: Alloprevotella tannerae ATCC 51259

Reference/BioCyc CPD-10134
type: UnificationXref
id: CPD-10134
db: BioCyc

(2,3-Dihydroxybenzoyl)adenylic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440201
xref: Reference/ChEBI CHEBI 5572
chemical formula: C17H18N5O10P
molecular weight: 483.07913
structure: ChemicalStructure/PW C041127

2,3-Dihydroxybenzoylserine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17455
xref: Reference/PubChem-compound 25244759
chemical formula: C10H11NO6
molecular weight: 241.05864
structure: ChemicalStructure/PW C043308

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Ferric enterobactin
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Ferric enterobactin

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

ABC transporter, ATP-binding protein
type: ProteinReference
xref: Reference/UniProt C9LGL5
organism: Alloprevotella tannerae ATCC 51259

Compound/PW C000458 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

TonB-dependent receptor
type: ProteinReference
xref: Reference/UniProt C9LDG0

Transport energizing protein, ExbD/TolR family
type: ProteinReference
xref: Reference/UniProt C9LCU9

Transporter, MotA/TolQ/ExbB proton channel family protein
type: ProteinReference
xref: Reference/UniProt C9LCV0

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

ChemicalStructure/PW C000120
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CO)C(O)=O

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005615
type: UnificationXref
id: GO:0005615
db: GENE ONTOLOGY

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

Compound/PW C043308/Stoichiometry/3.0
type: Stoichiometry
physical entity: 2,3-Dihydroxybenzoylserine
stoichiometric coefficient: 3.0

Protein/35273 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: ABC transporter, ATP-binding protein
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 29101
type: UnificationXref
id: CHEBI:29101
db: ChEBI

ChemicalStructure/PW C040741
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@]1(O)C(=CC=C[C@]1([H])OC(=C)C([O-])=O)C([O-])=O

Ferric enterobactin
type: SmallMoleculeReference
xref: Reference/PubChem-compound 440956
chemical formula: C30H33FeN3O15
molecular weight: 731.1261
structure: ChemicalStructure/PW C041655

Compound/PW C040034 Cytoplasm/Stoichiometry/3.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 3.0

Fe2+
type: SmallMoleculeReference
xref: Reference/CAS 15438-31-0
xref: Reference/KEGG Compound C14818
xref: Reference/ChemSpider 25394
xref: Reference/PubChem-compound 27284
xref: Reference/ChEBI CHEBI 29033
xref: Reference/BioCyc Ferric-Hydroxamate-Complexes
xref: Reference/HMDB HMDB0000692
chemical formula: Fe
molecular weight: 55.93494
structure: ChemicalStructure/PW C000544

Adenosine triphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine triphosphate

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Compound/PW C041655/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ferric enterobactin
stoichiometric coefficient: 1.0

Protein/35267/Stoichiometry/3.0
type: Stoichiometry
physical entity: Outer membrane efflux protein
stoichiometric coefficient: 3.0

Compound/PW C000164 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Chorismate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Chorismate
name: SubPathwayOutput

Reference/ChemSpider 899
type: UnificationXref
id: 899
db: ChemSpider

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

ReactionCatalysis555638
type: Catalysis
controller: Unknown
controlled: 5.4.4.2
control type: ACTIVATION

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Compound/PW C041655 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ferric enterobactin
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

ReactionCatalysis555639
type: Catalysis
controller: SsuA/THI5-like domain-containing protein
controlled: 6.3.2.14
control type: ACTIVATION

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C040793 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: enterobactin
stoichiometric coefficient: 1.0

Reaction3390
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041655 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000544 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040793 Cytoplasm/Stoichiometry/1.0
right: Fe2+
right: enterobactin
spontaneous: false
left: Ferric enterobactin
name: Ferric enterobactin → Fe2+ + enterobactin
conversion direction: LEFT_TO_RIGHT

Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

ReactionCatalysis555641
type: Catalysis
controller: 3-oxoacyl-[acyl-carrier-protein] reductase
controlled: 1.3.1.28
control type: ACTIVATION

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

ReactionCatalysis555640
type: Catalysis
controller: Secretion system C-terminal sorting domain-containing protein
controlled: Reaction561973
control type: ACTIVATION

Compound/PW C041655 Extracellular Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ferric enterobactin
stoichiometric coefficient: 1.0

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

ReactionCatalysis555643
type: Catalysis
controller: enterobactin synthase
controlled: 6.3.2.14
control type: ACTIVATION

ReactionCatalysis555642
type: Catalysis
controller: Unknown
controlled: Reaction561975
control type: ACTIVATION

enterobactin
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: enterobactin

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

Reference/SMPDB SMP0643902
type: UnificationXref
id: SMP0643902
db: SMPDB

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

Reference/CAS 17341-25-2
type: UnificationXref
id: 17341-25-2
db: CAS

Water
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Water

Compound/PW C000120 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0000826
type: UnificationXref
id: SMP0000826
db: SMPDB

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

AMP-binding enzyme
type: ProteinReference
xref: Reference/UniProt C9LI36
organism: Alloprevotella tannerae ATCC 51259

Compound/PW C040741/Stoichiometry/1.0
type: Stoichiometry
physical entity: isochorismate
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

isochorismate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: isochorismate

Reference/SMPDB SMP0000827
type: UnificationXref
id: SMP0000827
db: SMPDB

Chorismate
type: SmallMolecule
entity reference: Chorismate

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

4'-phosphopantetheinyl transferase family protein
type: Protein
cellular location: Cytoplasm
entity reference: 4'-phosphopantetheinyl transferase family protein

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

Reference/PubChem-compound 440201
type: UnificationXref
id: 440201
db: PubChem-compound

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
type: SmallMolecule
cellular location: Cytosol
entity reference: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

Reference/ChEBI CHEBI 29033
type: UnificationXref
id: CHEBI:29033
db: ChEBI

ChemicalStructure/PW C040770
type: ChemicalStructure
structure format: SMILES
structure data: OC1C=CC=C(C1O)C(O)=O

Reference/ChEBI CHEBI 29034
type: UnificationXref
id: CHEBI:29034
db: ChEBI

Fe3+
type: SmallMoleculeReference
xref: Reference/PubChem-compound 29936
xref: Reference/ChemSpider 27815
xref: Reference/KEGG Compound C14819
xref: Reference/BioCyc CPD-10134
xref: Reference/HMDB HMDB0012943
xref: Reference/CAS 20074-52-6
xref: Reference/ChEBI CHEBI 29034
chemical formula: Fe
molecular weight: 55.93494
structure: ChemicalStructure/PW C008133

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Compound/PW C000414 Cytoplasm/Stoichiometry/6.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 6.0

Reference/SMPDB SMP0000835
type: UnificationXref
id: SMP0000835
db: SMPDB

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/HMDB HMDB0012943
type: UnificationXref
id: HMDB0012943
db: HMDB

Reference/KEGG Compound C00065
type: UnificationXref
id: C00065
db: KEGG Compound

ReactionCoupledTransport4440
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C041655 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Inner Membrane/Stoichiometry/1.0
right: Adenosine diphosphate
right: Ferric enterobactin
right: Hydrogen Ion
spontaneous: false
left: Water
left: Adenosine triphosphate
left: Ferric enterobactin
name: Adenosine triphosphate + Ferric enterobactin + Water ? Adenosine diphosphate + Ferric enterobactin + Hydrogen Ion

Reference/ChEBI CHEBI 18026
type: UnificationXref
id: CHEBI:18026
db: ChEBI

Protein/35266 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: SsuA/THI5-like domain-containing protein
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Pyrophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyrophosphate

Alloprevotella tannerae ATCC 51259
type: BioSource
xref: Reference/TAXONOMY 626522

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/ChEBI CHEBI 28855
type: UnificationXref
id: CHEBI:28855
db: ChEBI

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

2,3-Dihydroxybenzoic acid
type: SmallMolecule
entity reference: 2,3-Dihydroxybenzoic acid

Reference/UniProt C9LI87
type: UnificationXref
id: C9LI87
db: UniProt

2,3-Dihydroxybenzoic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: 2,3-Dihydroxybenzoic acid

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Sodium
type: SmallMolecule
cellular location: Cytosol
entity reference: Sodium

Compound/PW C000458 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Sodium
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

3-oxoacyl-[acyl-carrier-protein] reductase
type: Protein
cellular location: Cytosol
entity reference: 3-oxoacyl-[acyl-carrier-protein] reductase

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

Compound/PW C000544 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fe2+
stoichiometric coefficient: 1.0

ChemicalStructure/PW C008133
type: ChemicalStructure
structure format: SMILES
structure data: [Fe+3]

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Compound/PW C040034/Stoichiometry/3.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 3.0

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

L-Serine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Serine

Compound/PW C041127/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2,3-Dihydroxybenzoyl)adenylic acid
stoichiometric coefficient: 1.0

Reference/PathWhiz PW000815
type: UnificationXref
id: PW000815
db: PathWhiz

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04171
xref: Reference/ChEBI CHEBI 15941
chemical formula: C7H8O4
molecular weight: 156.04225
structure: ChemicalStructure/PW C040770

Iron chelate uptake ABC transporter, FeCT family, permease protein
type: Protein
cellular location: Inner Membrane
entity reference: Iron chelate uptake ABC transporter, FeCT family, permease protein

Sodium
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Sodium

ChemicalStructure/PW C043308
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

ChemicalStructure/PW C041127
type: ChemicalStructure
structure format: SMILES

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/CAS 56-45-1
type: UnificationXref
id: 56-45-1
db: CAS

Reference/CAS 20074-52-6
type: UnificationXref
id: 20074-52-6
db: CAS

SsuA/THI5-like domain-containing protein
type: Protein
cellular location: Cytoplasm
entity reference: SsuA/THI5-like domain-containing protein

Reference/KEGG Compound C00885
type: UnificationXref
id: C00885
db: KEGG Compound

Reference/UniProt C9LKL3
type: UnificationXref
id: C9LKL3
db: UniProt

Reference/PathWhiz PW000807
type: UnificationXref
id: PW000807
db: PathWhiz

Compound/PW C040034 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

L-Serine
type: SmallMolecule
cellular location: Cytoplasm
entity reference: L-Serine

L-Serine
type: SmallMoleculeReference
xref: Reference/ChemSpider 5736
xref: Reference/ChEBI CHEBI 17115
xref: Reference/CAS 56-45-1
xref: Reference/KEGG Compound C00065
xref: Reference/PubChem-compound 5951
xref: Reference/HMDB HMDB0000187
xref: Reference/BioCyc SER
chemical formula: C3H7NO3
molecular weight: 105.042595
structure: ChemicalStructure/PW C000120

Reference/PathWhiz PW000806
type: UnificationXref
id: PW000806
db: PathWhiz

Reference/HMDB HMDB0000187
type: UnificationXref
id: HMDB0000187
db: HMDB

enterobactin
type: SmallMolecule
cellular location: Extracellular Space
entity reference: enterobactin

L-fucose:H+ symporter permease
type: Protein
entity reference: L-fucose:H+ symporter permease

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Compound/PW C008133/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fe3+
stoichiometric coefficient: 1.0

Reference/KEGG Compound C14819
type: UnificationXref
id: C14819
db: KEGG Compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/KEGG Compound C14818
type: UnificationXref
id: C14818
db: KEGG Compound

Reference/PathWhiz PW684247
type: UnificationXref
id: PW684247
db: PathWhiz

AMP-binding enzyme
type: Protein
cellular location: Cytoplasm
entity reference: AMP-binding enzyme

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Compound/PW C040741 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: isochorismate
stoichiometric coefficient: 1.0

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

2,3-Dihydroxybenzoic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18026
chemical formula: C7H5O4
molecular weight: 153.01933
structure: ChemicalStructure/PW C040792

Reaction561973
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/3.0
participant stoichiometry: Compound/PW C043308/Stoichiometry/3.0
participant stoichiometry: Compound/PW C008133/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041655/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/3.0
right: Hydrogen Ion
right: Fe3+
right: 2,3-Dihydroxybenzoylserine
spontaneous: false
left: Ferric enterobactin
left: Water
name: Ferric enterobactin + 3 Water → 3 2,3-Dihydroxybenzoylserine + Fe3+ + 3 Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/CAS 15438-31-0
type: UnificationXref
id: 15438-31-0
db: CAS

1.3.1.28
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040770 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040792 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: 2,3-Dihydroxybenzoic acid
right: Hydrogen Ion
right: NADH
spontaneous: false
EC number: 1.3.1.28
left: NAD
left: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD → 2,3-Dihydroxybenzoic acid + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

enterobactin
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 28855
chemical formula: C30H27N3O15
molecular weight: 669.1442
structure: ChemicalStructure/PW C040793

Ferric enterobactin
type: SmallMolecule
entity reference: Ferric enterobactin

Reaction561975
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040770 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040741 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164 Cytoplasm/Stoichiometry/1.0
right: Pyruvic acid
right: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate
spontaneous: false
left: Water
left: isochorismate
name: Water + isochorismate → (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

6.3.2.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000032 Cytoplasm/Stoichiometry/6.0
participant stoichiometry: Compound/PW C000170 Cytoplasm/Stoichiometry/6.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/6.0
participant stoichiometry: Compound/PW C000120 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/3.0
participant stoichiometry: Compound/PW C040793 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040792 Cytoplasm/Stoichiometry/3.0
right: Hydrogen Ion
right: Adenosine monophosphate
right: enterobactin
right: Pyrophosphate
spontaneous: false
EC number: 6.3.2.14
left: 2,3-Dihydroxybenzoic acid
left: Adenosine triphosphate
left: L-Serine
name: 3 2,3-Dihydroxybenzoic acid + 6 Adenosine triphosphate + 3 L-Serine → 6 Adenosine monophosphate + 3 Hydrogen Ion + 6 Pyrophosphate + enterobactin
conversion direction: LEFT_TO_RIGHT

Reference/UniProt C9LEN7
type: UnificationXref
id: C9LEN7
db: UniProt

Sodium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000588
xref: Reference/PubChem-compound 923
xref: Reference/KEGG Compound C01330
xref: Reference/ChEBI CHEBI 29101
xref: Reference/ChemSpider 899
xref: Reference/CAS 17341-25-2
chemical formula: Na
molecular weight: 22.989769
structure: ChemicalStructure/PW C000458

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

5.4.4.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040741/Stoichiometry/1.0
right: isochorismate
spontaneous: false
EC number: 5.4.4.2
left: Chorismate
name: Chorismate → isochorismate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 25394
type: UnificationXref
id: 25394
db: ChemSpider

6.3.2.14
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040792/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041127/Stoichiometry/1.0
right: (2,3-Dihydroxybenzoyl)adenylic acid
right: Pyrophosphate
spontaneous: false
EC number: 6.3.2.14
left: 2,3-Dihydroxybenzoic acid
left: Adenosine triphosphate
name: 2,3-Dihydroxybenzoic acid + Adenosine triphosphate ↔ (2,3-Dihydroxybenzoyl)adenylic acid + Pyrophosphate
conversion direction: REVERSIBLE

Reference/UniProt C9LG14
type: UnificationXref
id: C9LG14
db: UniProt

SsuA/THI5-like domain-containing protein
type: Protein
entity reference: SsuA/THI5-like domain-containing protein

TransportCatalysis18596
type: Catalysis
controller: L-fucose:H+ symporter permease
controlled: Transport35045
control type: ACTIVATION

Outer membrane efflux protein
type: Protein
entity reference: Outer membrane efflux protein

TransportCatalysis18597
type: Catalysis
controller: EntS-TolC Enterobactin Efflux Transport System
controlled: Transport35046
control type: ACTIVATION

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Compound/PW C001420 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

TransportCatalysis18598
type: Catalysis
controller: ferric enterobactin outer membrane transport complex
controlled: Transport35047
control type: ACTIVATION

Penicillin-binding protein, transpeptidase domain protein
type: Protein
entity reference: Penicillin-binding protein, transpeptidase domain protein

TransportCatalysis18599
type: Catalysis
controller: Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein
controlled: Transport35048
control type: ACTIVATION

Transporter, MotA/TolQ/ExbB proton channel family protein
type: Protein
entity reference: Transporter, MotA/TolQ/ExbB proton channel family protein

Transport energizing protein, ExbD/TolR family
type: Protein
entity reference: Transport energizing protein, ExbD/TolR family

TonB-dependent receptor
type: Protein
entity reference: TonB-dependent receptor

Adenosine diphosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Adenosine diphosphate

enterobactin
type: SmallMolecule
cellular location: Cytosol
entity reference: enterobactin

Compound/PW C040792/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2,3-Dihydroxybenzoic acid
stoichiometric coefficient: 1.0