Biosynthesis of Siderophore Group Nonribosomal Peptides
Bacteroides coprophilus DSM 18228 = JCM 13818
3 2,3-Dihydroxybenzoic acid + 6 Adenosine triphosphate + 3 L-Serine → 6 Adenosine monophosphate + 3 Hydrogen Ion + 6 Pyrophosphate + enterobactin
Water + isochorismate → (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + Pyruvic acid
Adenosine triphosphate + Ferric enterobactin + Water ? Adenosine diphosphate + Ferric enterobactin + Hydrogen Ion
enterobactin (→) Transport: Bacteroides coprophilus DSM 18228 = JCM 13818, Cytosol to Bacteroides coprophilus DSM 18228 = JCM 13818, Periplasmic Space
Ferric enterobactin → Fe2+ + enterobactin
L-Serine (→), Sodium (→) Transport: Bacteroides coprophilus DSM 18228 = JCM 13818, Periplasmic Space to Bacteroides coprophilus DSM 18228 = JCM 13818, Cytosol
enterobactin (→) Transport: Bacteroides coprophilus DSM 18228 = JCM 13818, Periplasmic Space to Bacteroides coprophilus DSM 18228 = JCM 13818, Extracellular Space
Ferric enterobactin (→) Transport: Bacteroides coprophilus DSM 18228 = JCM 13818, Extracellular Space to Bacteroides coprophilus DSM 18228 = JCM 13818, Periplasmic Space
Ferric enterobactin + 3 Water → 3 2,3-Dihydroxybenzoylserine + Fe3+ + 3 Hydrogen Ion
(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD → 2,3-Dihydroxybenzoic acid + Hydrogen Ion + NADH
2,3-Dihydroxybenzoic acid + Adenosine triphosphate ↔ (2,3-Dihydroxybenzoyl)adenylic acid + Pyrophosphate