Biosynthesis of Siderophore Group Nonribosomal Peptides
3 2,3-Dihydroxybenzoic acid + 6 Adenosine triphosphate + 3 L-Serine → 6 Adenosine monophosphate + 3 Hydrogen Ion + 6 Pyrophosphate + enterobactin
(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD → 2,3-Dihydroxybenzoic acid + Hydrogen Ion + NADH
Water + isochorismate → (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + Pyruvic acid
Ferric enterobactin + 3 Water → 3 2,3-Dihydroxybenzoylserine + Fe3+ + 3 Hydrogen Ion
2,3-Dihydroxybenzoic acid + Adenosine triphosphate ↔ (2,3-Dihydroxybenzoyl)adenylic acid + Pyrophosphate
enterobactin (→) Transport: Afipia birgiae 34632, Cytosol to Afipia birgiae 34632, Periplasmic Space
L-Serine (→), Sodium (→) Transport: Afipia birgiae 34632, Periplasmic Space to Afipia birgiae 34632, Cytosol
enterobactin (→) Transport: Afipia birgiae 34632, Periplasmic Space to Afipia birgiae 34632, Extracellular Space
Ferric enterobactin (→) Transport: Afipia birgiae 34632, Extracellular Space to Afipia birgiae 34632, Periplasmic Space
Ferric enterobactin → Fe2+ + enterobactin
EntS-TolC Enterobactin Efflux Transport System
Adenosine triphosphate + Ferric enterobactin + Water ? Adenosine diphosphate + Ferric enterobactin + Hydrogen Ion