L-Valine (→) Transport: Escherichia coli (strain 55989 / EAEC), Cytosol to Escherichia coli (strain 55989 / EAEC), Periplasmic Space
(R)-2,3-Dihydroxy-isovalerate → Isovaleric acid + Water
Hydrogen Ion + 2 Pyruvic acid → (S)-2-Acetolactate + Carbon dioxide
Isovaleric acid + L-Glutamic acid → L-Valine + Oxoglutaric acid
(S)-2-Acetolactate + Hydrogen Ion + NADPH → (R)-2,3-Dihydroxy-isovalerate + NADP
acetolactate synthase / acetohydroxybutanoate synthase
acetohydroxybutanoate synthase / acetolactate synthase