Reference/ChemSpider 1005
type: UnificationXref
id: 1005
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C000159 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionic acid
stoichiometric coefficient: 1.0

Oxalacetic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000223
xref: Reference/CAS 328-42-7
xref: Reference/ChEBI CHEBI 30744
xref: Reference/BioCyc OXALACETIC ACID
xref: Reference/ChemSpider 945
xref: Reference/PubChem-compound 970
xref: Reference/KEGG Compound C00036
chemical formula: C4H4O5
molecular weight: 132.00587
structure: ChemicalStructure/PW C000148

Reference/PubChem-compound 439161
type: UnificationXref
id: 439161
db: PubChem-compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

2.3.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000092 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000003 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988 Cytosol/Stoichiometry/1.0
right: Formic acid
right: Propionyl-CoA
spontaneous: false
EC number: 2.3.1.-
left: Coenzyme A
left: 2-Ketobutyric acid
name: 2-Ketobutyric acid + Coenzyme A → Formic acid + Propionyl-CoA
conversion direction: LEFT_TO_RIGHT

propanoyl phosphate
type: SmallMolecule
entity reference: propanoyl phosphate

Succinic acid
type: SmallMolecule
entity reference: Succinic acid

Reference/ChemSpider 498
type: UnificationXref
id: 498
db: ChemSpider

2.3.1.8
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042933 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
right: Coenzyme A
right: propanoyl phosphate
spontaneous: false
EC number: 2.3.1.8
left: Phosphate
left: Propionyl-CoA
name: Phosphate + Propionyl-CoA → Coenzyme A + propanoyl phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 57
type: UnificationXref
id: 57
db: ChemSpider

SubPathwayInteraction485696
type: Interaction
name: SubPathwayReaction
name: SubPathway485696Reaction
participant: L-Threonine

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

SubPathwayInteraction485697
type: Interaction
name: SubPathway485697Reaction
name: SubPathwayReaction
participant: Pyruvic acid

2-Methylcitric acid
type: SmallMoleculeReference
xref: Reference/ChemSpider 500
xref: Reference/PubChem-compound 515
xref: Reference/ChEBI CHEBI 30835
xref: Reference/HMDB HMDB0000379
xref: Reference/CAS 6061-96-7
chemical formula: C7H10O7
molecular weight: 206.04265
structure: ChemicalStructure/PW C000278

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Unknown
type: ProteinReference

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Threonine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway485696
pathway component: SubPathwayInteraction485696
xref: Reference/SMPDB SMP0000837
xref: Reference/PathWhiz PW000817
name: SubPathway

Propionic acid
type: SmallMoleculeReference
xref: Reference/BioCyc PROPIONATE
xref: Reference/ChemSpider 1005
xref: Reference/HMDB HMDB0000237
xref: Reference/ChEBI CHEBI 30768
xref: Reference/CAS 79-09-4
xref: Reference/KEGG Compound C00163
xref: Reference/PubChem-compound 1032
chemical formula: C3H6O2
molecular weight: 74.03678
structure: ChemicalStructure/PW C000159

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/KEGG Compound C00683
type: UnificationXref
id: C00683
db: KEGG Compound

Reference/BioCyc OXALACETIC ACID
type: UnificationXref
id: OXALACETIC_ACID
db: BioCyc

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

2.7.2.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000159/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042933/Stoichiometry/1.0
right: Propionic acid
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.2.1
left: Adenosine diphosphate
left: propanoyl phosphate
name: Adenosine diphosphate + propanoyl phosphate → Adenosine triphosphate + Propionic acid
conversion direction: LEFT_TO_RIGHT

Ammonium
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0041827
xref: Reference/CAS 14798-03-9
xref: Reference/PubChem-compound 16741146
xref: Reference/KEGG Compound C01342
xref: Reference/ChEBI CHEBI 28938
xref: Reference/ChemSpider 218
chemical formula: H4N
molecular weight: 18.034374
structure: ChemicalStructure/PW C022608

Protein/29051 Cytosol/Stoichiometry/6.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 6.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/CAS 328-42-7
type: UnificationXref
id: 328-42-7
db: CAS

4.1.1.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000982/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988/Stoichiometry/1.0
right: Carbon dioxide
right: Propionyl-CoA
spontaneous: false
EC number: 4.1.1.41
left: Hydrogen Ion
left: Methylmalonyl-CoA
name: Hydrogen Ion + Methylmalonyl-CoA → Carbon dioxide + Propionyl-CoA
conversion direction: LEFT_TO_RIGHT

ReactionCatalysis1103437
type: Catalysis
controller: threonine deaminase
controlled: 4.3.1.19
control type: ACTIVATION

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

ChemicalStructure/PW C002761
type: ChemicalStructure
structure format: SMILES
structure data: CC(O)(C(CC(O)=O)C(O)=O)C(O)=O

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid
name: SubPathwayInput

2.8.3.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000174 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000159 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000808 Cytosol/Stoichiometry/1.0
right: Propionic acid
right: Succinyl-CoA
spontaneous: false
EC number: 2.8.3.-
left: Propionyl-CoA
left: Succinic acid
name: Propionyl-CoA + Succinic acid → Propionic acid + Succinyl-CoA
conversion direction: LEFT_TO_RIGHT

2-Ketobutyric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 2-Ketobutyric acid

Reference/ChEBI CHEBI 15607
type: UnificationXref
id: CHEBI:15607
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/PubChem-compound 19796801
type: UnificationXref
id: 19796801
db: PubChem-compound

Reference/PubChem-compound 58
type: UnificationXref
id: 58
db: PubChem-compound

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/PubChem-compound 6288
type: UnificationXref
id: 6288
db: PubChem-compound

Reaction2924
type: BiochemicalReaction
participant stoichiometry: Compound/PW C022608/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000003/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Ammonium
right: 2-Ketobutyric acid
spontaneous: true
left: 2-iminobutanoate
left: Water
left: Hydrogen Ion
name: 2-iminobutanoate + Hydrogen Ion + Water → 2-Ketobutyric acid + Ammonium
conversion direction: LEFT_TO_RIGHT

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15380
type: UnificationXref
id: CHEBI:15380
db: ChEBI

Reference/BioCyc THR
type: UnificationXref
id: THR
db: BioCyc

Propionic acid
type: SmallMolecule
entity reference: Propionic acid

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

2-Methylcitric acid
type: SmallMolecule
entity reference: 2-Methylcitric acid

Succinyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00091
xref: Reference/CAS 604-98-8
xref: Reference/ChemSpider 388307
xref: Reference/PubChem-compound 439161
xref: Reference/ChEBI CHEBI 15380
xref: Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
xref: Reference/HMDB HMDB0001022
chemical formula: C25H40N7O19P3S
molecular weight: 867.1312
structure: ChemicalStructure/PW C000808

Reference/PubChem-compound 1032
type: UnificationXref
id: 1032
db: PubChem-compound

ReactionCatalysis1103431
type: Catalysis
controller: pyruvate formate-lyase / 2-ketobutyrate formate-lyase
controlled: 2.3.1.-
control type: ACTIVATION

ReactionCatalysis1103432
type: Catalysis
controller: Unknown
controlled: 2.3.1.-
control type: ACTIVATION

Compound/PW C000092 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Formic acid
stoichiometric coefficient: 1.0

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/ChemSpider 278
type: UnificationXref
id: 278
db: ChemSpider

ReactionCatalysis1103426
type: Catalysis
controller: phosphate acetyltransferase / phosphate propionyltransferase
controlled: 2.3.1.8
control type: ACTIVATION

Adenosine monophosphate
type: SmallMolecule
entity reference: Adenosine monophosphate

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reaction2923
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040940/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040939/Stoichiometry/1.0
right: 2-iminobutanoate
spontaneous: true
left: (2Z)-2-aminobut-2-enoate
name: (2Z)-2-aminobut-2-enoate → 2-iminobutanoate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 104809-02-1
type: UnificationXref
id: 104809-02-1
db: CAS

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

propanoyl phosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 22003434
chemical formula: C3H5O5P
molecular weight: 151.98856
structure: ChemicalStructure/PW C042933

Reference/KEGG Compound C00109
type: UnificationXref
id: C00109
db: KEGG Compound

Reference/KEGG Compound C00100
type: UnificationXref
id: C00100
db: KEGG Compound

ReactionCatalysis1103422
type: Catalysis
controller: Unknown
controlled: 2.7.2.1
control type: ACTIVATION

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Oxalacetic acid
type: SmallMolecule
entity reference: Oxalacetic acid

ReactionCatalysis1103423
type: Catalysis
controller: Unknown
controlled: 2.7.2.1
control type: ACTIVATION

Reference/SMPDB SMP0645141
type: UnificationXref
id: SMP0645141
db: SMPDB

Reference/ChemSpider 945
type: UnificationXref
id: 945
db: ChemSpider

ChemicalStructure/PW C040939
type: ChemicalStructure
structure format: SMILES
structure data: CC=C(N)C([O-])=O

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/PubChem-compound 439291
type: UnificationXref
id: 439291
db: PubChem-compound

ChemicalStructure/PW C002736
type: ChemicalStructure
structure format: SMILES
structure data: C\C(C(O)=O)=C(/CC(O)=O)C(O)=O

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/PathWhiz PW685486
type: UnificationXref
id: PW685486
db: PathWhiz

4.3.1.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000109/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040939/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Water
right: (2Z)-2-aminobut-2-enoate
right: Hydrogen Ion
spontaneous: false
EC number: 4.3.1.19
left: L-Threonine
name: L-Threonine → (2Z)-2-aminobut-2-enoate + Hydrogen Ion + Water
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 30768
type: UnificationXref
id: CHEBI:30768
db: ChEBI

Reference/PubChem-compound 439164
type: UnificationXref
id: 439164
db: PubChem-compound

Reference/CAS 600-18-0
type: UnificationXref
id: 600-18-0
db: CAS

ReactionCatalysis1103417
type: Catalysis
controller: Unknown
controlled: 2.8.3.-
control type: ACTIVATION

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

ChemicalStructure/PW C000808
type: ChemicalStructure
structure format: SMILES

Compound/PW C000032/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Protein/29051/Stoichiometry/6.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 6.0

Propionyl-CoA
type: SmallMoleculeReference
xref: Reference/CAS 317-66-8
xref: Reference/PubChem-compound 439164
xref: Reference/KEGG Compound C00100
xref: Reference/ChEBI CHEBI 15539
xref: Reference/BioCyc PROPIONYL-COA
xref: Reference/ChemSpider 388310
xref: Reference/HMDB HMDB0001275
chemical formula: C24H40N7O17P3S
molecular weight: 823.1414
structure: ChemicalStructure/PW C000988

Ammonium
type: SmallMolecule
entity reference: Ammonium

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16857
type: UnificationXref
id: CHEBI:16857
db: ChEBI

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/PubChem-compound 22003434
type: UnificationXref
id: 22003434
db: PubChem-compound

ReactionCatalysis1103414
type: Catalysis
controller: methylmalonyl-CoA decarboxylase
controlled: 4.1.1.41
control type: ACTIVATION

Reference/ChemSpider 388310
type: UnificationXref
id: 388310
db: ChemSpider

Reference/ChemSpider 218
type: UnificationXref
id: 218
db: ChemSpider

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/BioCyc SUC
type: UnificationXref
id: SUC
db: BioCyc

ReactionCatalysis1103409
type: Catalysis
controller: methylmalonyl-CoA mutase
controlled: 5.4.99.2
control type: ACTIVATION

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Reference/CAS 72-19-5
type: UnificationXref
id: 72-19-5
db: CAS

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ReactionCatalysis1103406
type: Catalysis
controller: 2-methylisocitrate lyase
controlled: 4.1.3.30
control type: ACTIVATION

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Compound/PW C000808 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinyl-CoA
stoichiometric coefficient: 1.0

Compound/PW C040940/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-iminobutanoate
stoichiometric coefficient: 1.0

Reference/CAS 6061-93-4
type: UnificationXref
id: 6061-93-4
db: CAS

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

2-iminobutanoate
type: SmallMolecule
entity reference: 2-iminobutanoate

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

ReactionCatalysis1103400
type: Catalysis
controller: Unknown
controlled: 4.2.1.79
control type: ACTIVATION

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc PROPIONYL-COA
type: UnificationXref
id: PROPIONYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

ReactionCatalysis1103403
type: Catalysis
controller: bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
controlled: 4.2.1.3
control type: ACTIVATION

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/BioCyc 2-OXOBUTANOATE
type: UnificationXref
id: 2-OXOBUTANOATE
db: BioCyc

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

(2Z)-2-aminobut-2-enoate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58739
chemical formula: C4H6NO2
molecular weight: 100.040405
structure: ChemicalStructure/PW C040939

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/HMDB HMDB0000223
type: UnificationXref
id: HMDB0000223
db: HMDB

Reference/ChemSpider 6051
type: UnificationXref
id: 6051
db: ChemSpider

(2Z)-2-aminobut-2-enoate
type: SmallMolecule
entity reference: (2Z)-2-aminobut-2-enoate

Succinyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Succinyl-CoA

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway485697
pathway component: SubPathwayInteraction485697
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Reference/ChEBI CHEBI 15741
type: UnificationXref
id: CHEBI:15741
db: ChEBI

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
cellular location: Cytosol
entity reference: Coenzyme A

2-iminobutanoate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 19796801
chemical formula: C4H6NO2
molecular weight: 100.040405
structure: ChemicalStructure/PW C040940

Compound/PW C000174 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

propanoyl phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: propanoyl phosphate

TransportCatalysis30506
type: Catalysis
controller: Unknown
controlled: Transport48888
control type: ACTIVATION

Reference/KEGG Compound C01342
type: UnificationXref
id: C01342
db: KEGG Compound

Reference/PubChem-compound 3080625
type: UnificationXref
id: 3080625
db: PubChem-compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/ChEBI CHEBI 28938
type: UnificationXref
id: CHEBI:28938
db: ChEBI

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/PubChem-compound 1110
type: UnificationXref
id: 1110
db: PubChem-compound

ChemicalStructure/PW C000109
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](O)[C@H](N)C(O)=O

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/TAXONOMY 1122985
type: UnificationXref
id: 1122985
db: TAXONOMY

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/HMDB HMDB0000237
type: UnificationXref
id: HMDB0000237
db: HMDB

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Transport69942
type: Transport
participant stoichiometry: Compound/PW C000159 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000159 Cytosol/Stoichiometry/1.0
right: Propionic acid
spontaneous: false
left: Propionic acid
name: Propionic acid (→) Transport: Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930, Periplasmic Space to Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Succinic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000254
xref: Reference/CAS 110-15-6
xref: Reference/ChEBI CHEBI 15741
xref: Reference/KEGG Compound C00042
xref: Reference/ChemSpider 1078
xref: Reference/PubChem-compound 1110
xref: Reference/BioCyc SUC
chemical formula: C4H6O4
molecular weight: 118.02661
structure: ChemicalStructure/PW C000174

2-methylcitrate synthase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/2.0
component: Unknown

Reference/ChemSpider 388424
type: UnificationXref
id: 388424
db: ChemSpider

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388307
type: UnificationXref
id: 388307
db: ChemSpider

Compound/PW C000003/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Ketobutyric acid
stoichiometric coefficient: 1.0

Compound/PW C000159 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

Compound/PW C002761/Stoichiometry/1.0
type: Stoichiometry
physical entity: Methylisocitric acid
stoichiometric coefficient: 1.0

Methylmalonyl-CoA
type: SmallMolecule
entity reference: Methylmalonyl-CoA

Propionyl-CoA
type: SmallMolecule
entity reference: Propionyl-CoA

Compound/PW C000988/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionyl-CoA
stoichiometric coefficient: 1.0

Reference/CAS 317-66-8
type: UnificationXref
id: 317-66-8
db: CAS

2-methylisocitrate lyase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/4.0
component: Unknown

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

L-Threonine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Threonine

Propanoate Metabolism
type: Pathway
pathway order: PathwaySubPathway/485697
pathway order: PathwayEnzymeReaction/6559267
pathway order: PathwayEnzymeReaction/6559312
pathway order: PathwayEnzymeReaction/6559265
pathway order: PathwayEnzymeReaction/6559298
pathway order: PathwayEnzymeReaction/6559320
pathway order: PathwayEnzymeReaction/6559266
pathway order: PathwayEnzymeReaction/6559277
pathway order: PathwayEnzymeReaction/6559288
pathway order: PathwayEnzymeReaction/6559304
pathway order: PathwayEnzymeReaction/6559305
pathway order: PathwayEnzymeReaction/6559313
pathway order: PathwayEnzymeReaction/6559303
pathway order: PathwayTransport/6559331
pathway order: PathwayTransport/6559333
pathway order: PathwayEnzymeReaction/6559280
pathway order: PathwayEnzymeReaction/6559274
pathway order: PathwayEnzymeReaction/6559264
pathway order: PathwayEnzymeReaction/6559283
pathway order: PathwayEnzymeReaction/6559295
pathway order: PathwaySubPathway/485696
pathway component: ReactionCatalysis1103393
pathway component: ReactionCatalysis1103394
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: TransportCatalysis50471
pathway component: Reaction2924
pathway component: TransportCatalysis30506
pathway component: 4.1.3.30
pathway component: 2.3.1.-
pathway component: 5.4.99.2
pathway component: ReactionCatalysis1103414
pathway component: ReactionCatalysis1103397
pathway component: ReactionCatalysis1103431
pathway component: ReactionCatalysis1103432
pathway component: ReactionCatalysis1103409
pathway component: 2.3.1.8
pathway component: ReactionCatalysis1103426
pathway component: 4.2.1.3
pathway component: ReactionCatalysis1103406
pathway component: Transport69942
pathway component: Reaction2923
pathway component: Transport48888
pathway component: Threonine Biosynthesis
pathway component: ReactionCatalysis1103400
pathway component: ReactionCatalysis1103422
pathway component: ReactionCatalysis1103423
pathway component: 2.3.3.5
pathway component: ReactionCatalysis1103403
pathway component: 2.7.2.1
pathway component: 4.2.1.79
pathway component: 4.3.1.19
pathway component: 4.1.1.41
pathway component: ReactionCatalysis1103437
pathway component: ReactionCatalysis1103417
pathway component: 6.2.1.1
pathway component: 2.8.3.-
xref: Reference/PathWhiz PW685486
xref: Reference/SMPDB SMP0645141
organism: Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/HMDB HMDB0000005
type: UnificationXref
id: HMDB0000005
db: HMDB

ChemicalStructure/PW C000003
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=O)C(O)=O

bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/2.0
component: Unknown

Methylmalonyl-CoA
type: SmallMoleculeReference
xref: Reference/ChemSpider 388424
xref: Reference/HMDB HMDB0001269
xref: Reference/ChEBI CHEBI 15466
xref: Reference/BioCyc METHYL-MALONYL-COA
xref: Reference/KEGG Compound C00683
xref: Reference/CAS 104809-02-1
xref: Reference/PubChem-compound 439291
chemical formula: C25H40N7O19P3S
molecular weight: 867.1312
structure: ChemicalStructure/PW C000982

Reference/CAS 79-09-4
type: UnificationXref
id: 79-09-4
db: CAS

Reference/ChEBI CHEBI 16717
type: UnificationXref
id: CHEBI:16717
db: ChEBI

Reference/HMDB HMDB0006471
type: UnificationXref
id: HMDB0006471
db: HMDB

Protein/29051/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Propionic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Propionic acid

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/KEGG Compound C00036
type: UnificationXref
id: C00036
db: KEGG Compound

Reference/ChEBI CHEBI 30831
type: UnificationXref
id: CHEBI:30831
db: ChEBI

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Reference/HMDB HMDB0000254
type: UnificationXref
id: HMDB0000254
db: HMDB

Formic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Formic acid

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

ChemicalStructure/PW C000174
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(O)=O

Reference/ChEBI CHEBI 30835
type: UnificationXref
id: CHEBI:30835
db: ChEBI

Reference/HMDB HMDB0000379
type: UnificationXref
id: HMDB0000379
db: HMDB

Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930
type: BioSource
xref: Reference/TAXONOMY 1122985

Reference/HMDB HMDB0006357
type: UnificationXref
id: HMDB0006357
db: HMDB

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

ChemicalStructure/PW C042933
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=O)OP([O-])([O-])=O

Reference/PubChem-compound 515
type: UnificationXref
id: 515
db: PubChem-compound

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/PubChem-compound 513
type: UnificationXref
id: 513
db: PubChem-compound

Reference/KEGG Compound C00163
type: UnificationXref
id: C00163
db: KEGG Compound

Reference/KEGG Compound C00042
type: UnificationXref
id: C00042
db: KEGG Compound

Protein/29051 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

cis-2-Methylaconitate
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-1136
xref: Reference/PubChem-compound 3080625
xref: Reference/HMDB HMDB0006357
xref: Reference/ChEBI CHEBI 16717
xref: Reference/ChemSpider 2338376
xref: Reference/KEGG Compound C04225
xref: Reference/CAS 6061-93-4
chemical formula: C7H8O6
molecular weight: 188.03209
structure: ChemicalStructure/PW C002736

Reference/ChemSpider 1078
type: UnificationXref
id: 1078
db: ChemSpider

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Compound/PW C000808/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinyl-CoA
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Reference/CAS 604-98-8
type: UnificationXref
id: 604-98-8
db: CAS

Compound/PW C000278/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Methylcitric acid
stoichiometric coefficient: 1.0

Reference/CAS 14798-03-9
type: UnificationXref
id: 14798-03-9
db: CAS

ChemicalStructure/PW C000982
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 58739
type: UnificationXref
id: CHEBI:58739
db: ChEBI

Reference/PubChem-compound 18971002
type: UnificationXref
id: 18971002
db: PubChem-compound

Reference/HMDB HMDB0000142
type: UnificationXref
id: HMDB0000142
db: HMDB

ReactionCatalysis1103393
type: Catalysis
controller: Unknown
controlled: 6.2.1.1
control type: ACTIVATION

ReactionCatalysis1103394
type: Catalysis
controller: Unknown
controlled: 6.2.1.1
control type: ACTIVATION

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

TransportCatalysis50471
type: Catalysis
controller: Unknown
controlled: Transport69942
control type: ACTIVATION

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

cis-2-Methylaconitate
type: SmallMolecule
entity reference: cis-2-Methylaconitate

ChemicalStructure/PW C000148
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CC(=O)C(O)=O

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

ReactionCatalysis1103397
type: Catalysis
controller: 2-methylcitrate synthase
controlled: 2.3.3.5
control type: ACTIVATION

Reference/KEGG Compound C00058
type: UnificationXref
id: C00058
db: KEGG Compound

L-Threonine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Threonine

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

Formic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30751
xref: Reference/ChemSpider 278
xref: Reference/PubChem-compound 18971002
xref: Reference/BioCyc FORMATE
xref: Reference/CAS 64-18-6
xref: Reference/KEGG Compound C00058
xref: Reference/HMDB HMDB0000142
chemical formula: CH2O2
molecular weight: 46.005478
structure: ChemicalStructure/PW C000092

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000278
type: ChemicalStructure
structure format: SMILES
structure data: CC(C(O)=O)C(O)(CC(O)=O)C(O)=O

Reference/ChEBI CHEBI 15539
type: UnificationXref
id: CHEBI:15539
db: ChEBI

Reference/CAS 6061-96-7
type: UnificationXref
id: 6061-96-7
db: CAS

Reference/BioCyc FORMATE
type: UnificationXref
id: FORMATE
db: BioCyc

ChemicalStructure/PW C022608
type: ChemicalStructure
structure format: SMILES
structure data: [NH4+]

Reference/SMPDB SMP0000837
type: UnificationXref
id: SMP0000837
db: SMPDB

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Reference/KEGG Compound C00188
type: UnificationXref
id: C00188
db: KEGG Compound

ChemicalStructure/PW C000159
type: ChemicalStructure
structure format: SMILES
structure data: CCC(O)=O

Compound/PW C000982/Stoichiometry/1.0
type: Stoichiometry
physical entity: Methylmalonyl-CoA
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/HMDB HMDB0000167
type: UnificationXref
id: HMDB0000167
db: HMDB

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Compound/PW C000109/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

methylmalonyl-CoA decarboxylase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/6.0
component: Unknown

Succinic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Succinic acid

methylmalonyl-CoA mutase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/2.0
component: Unknown

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Compound/PW C000159/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionic acid
stoichiometric coefficient: 1.0

L-Threonine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000167
xref: Reference/PubChem-compound 6288
xref: Reference/CAS 72-19-5
xref: Reference/ChemSpider 6051
xref: Reference/ChEBI CHEBI 16857
xref: Reference/KEGG Compound C00188
xref: Reference/BioCyc THR
chemical formula: C4H9NO3
molecular weight: 119.05824
structure: ChemicalStructure/PW C000109

Compound/PW C000109 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

Protein/29051/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

ChemicalStructure/PW C040940
type: ChemicalStructure
structure format: SMILES
structure data: CCC(=N)C([O-])=O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Compound/PW C000174/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinic acid
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/CAS 110-15-6
type: UnificationXref
id: 110-15-6
db: CAS

Reference/HMDB HMDB0001269
type: UnificationXref
id: HMDB0001269
db: HMDB

Reference/ChEBI CHEBI 30751
type: UnificationXref
id: CHEBI:30751
db: ChEBI

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Compound/PW C042933 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: propanoyl phosphate
stoichiometric coefficient: 1.0

Compound/PW C040939/Stoichiometry/1.0
type: Stoichiometry
physical entity: (2Z)-2-aminobut-2-enoate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/PathWhiz PW000817
type: UnificationXref
id: PW000817
db: PathWhiz

Reference/BioCyc CPD-618
type: UnificationXref
id: CPD-618
db: BioCyc

Reference/HMDB HMDB0001022
type: UnificationXref
id: HMDB0001022
db: HMDB

ChemicalStructure/PW C000092
type: ChemicalStructure
structure format: SMILES
structure data: OC=O

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Compound/PW C002736/Stoichiometry/1.0
type: Stoichiometry
physical entity: cis-2-Methylaconitate
stoichiometric coefficient: 1.0

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Succinyl-CoA
type: SmallMolecule
entity reference: Succinyl-CoA

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

2-Ketobutyric acid
type: SmallMolecule
entity reference: 2-Ketobutyric acid

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Compound/PW C022608/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ammonium
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00091
type: UnificationXref
id: C00091
db: KEGG Compound

pyruvate formate-lyase / 2-ketobutyrate formate-lyase
type: Complex
component stoichiometry: Protein/29051 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Unknown

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc METHYL-MALONYL-COA
type: UnificationXref
id: METHYL-MALONYL-COA
db: BioCyc

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/ChEBI CHEBI 30744
type: UnificationXref
id: CHEBI:30744
db: ChEBI

2-Ketobutyric acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 30831
xref: Reference/HMDB HMDB0000005
xref: Reference/CAS 600-18-0
xref: Reference/ChemSpider 57
xref: Reference/KEGG Compound C00109
xref: Reference/PubChem-compound 58
xref: Reference/BioCyc 2-OXOBUTANOATE
chemical formula: C4H6O3
molecular weight: 102.03169
structure: ChemicalStructure/PW C000003

Reference/HMDB HMDB0001275
type: UnificationXref
id: HMDB0001275
db: HMDB

Reference/BioCyc PROPIONATE
type: UnificationXref
id: PROPIONATE
db: BioCyc

Compound/PW C000003 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Ketobutyric acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChEBI CHEBI 15466
type: UnificationXref
id: CHEBI:15466
db: ChEBI

Reference/BioCyc CPD-1136
type: UnificationXref
id: CPD-1136
db: BioCyc

Propionyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Propionyl-CoA

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Reference/PubChem-compound 16741146
type: UnificationXref
id: 16741146
db: PubChem-compound

4.1.3.30
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002761/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
right: Succinic acid
right: Pyruvic acid
spontaneous: false
EC number: 4.1.3.30
left: Methylisocitric acid
name: Methylisocitric acid → Pyruvic acid + Succinic acid
conversion direction: LEFT_TO_RIGHT

Unknown
type: Protein
entity reference: Unknown

5.4.99.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000808/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000982/Stoichiometry/1.0
right: Methylmalonyl-CoA
spontaneous: false
EC number: 5.4.99.2
left: Succinyl-CoA
name: Succinyl-CoA → Methylmalonyl-CoA
conversion direction: LEFT_TO_RIGHT

Reference/CAS 64-18-6
type: UnificationXref
id: 64-18-6
db: CAS

ChemicalStructure/PW C000988
type: ChemicalStructure
structure format: SMILES

Compound/PW C001099 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

4.2.1.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002736/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002761/Stoichiometry/1.0
right: Methylisocitric acid
right: Water
spontaneous: false
EC number: 4.2.1.3
left: cis-2-Methylaconitate
name: cis-2-Methylaconitate → Methylisocitric acid + Water
conversion direction: LEFT_TO_RIGHT

Compound/PW C042933/Stoichiometry/1.0
type: Stoichiometry
physical entity: propanoyl phosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 2338376
type: UnificationXref
id: 2338376
db: ChemSpider

Transport48888
type: Transport
participant stoichiometry: Compound/PW C000109 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000109 Cytosol/Stoichiometry/1.0
right: L-Threonine
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: L-Threonine
name: L-Threonine (→), Hydrogen Ion (→) Transport: Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930, Periplasmic Space to Prevotella loescheii DSM 19665 = JCM 12249 = ATCC 15930, Cytosol
conversion direction: LEFT_TO_RIGHT

Compound/PW C000148/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxalacetic acid
stoichiometric coefficient: 1.0

Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
type: UnificationXref
id: 3-METHYLBENZYLSUCCINYL-COA
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

phosphate acetyltransferase / phosphate propionyltransferase
type: Complex
component stoichiometry: Protein/29051 Cytosol/Stoichiometry/6.0
cellular location: Cytosol
component: Unknown

threonine deaminase
type: Complex
component stoichiometry: Protein/29051/Stoichiometry/4.0
component: Unknown

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/HMDB HMDB0041827
type: UnificationXref
id: HMDB0041827
db: HMDB

Compound/PW C000988 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Propionyl-CoA
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Propionic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Propionic acid

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

2.3.3.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000278/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000148/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988/Stoichiometry/1.0
right: Coenzyme A
right: Hydrogen Ion
right: 2-Methylcitric acid
spontaneous: false
EC number: 2.3.3.5
left: Water
left: Oxalacetic acid
left: Propionyl-CoA
name: Oxalacetic acid + Propionyl-CoA + Water → 2-Methylcitric acid + Coenzyme A + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

L-Threonine
type: SmallMolecule
entity reference: L-Threonine
name: SubPathwayOutput

Reference/PubChem-compound 970
type: UnificationXref
id: 970
db: PubChem-compound

4.2.1.79
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000278/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002736/Stoichiometry/1.0
right: Water
right: cis-2-Methylaconitate
spontaneous: false
EC number: 4.2.1.79
left: 2-Methylcitric acid
name: 2-Methylcitric acid → Water + cis-2-Methylaconitate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C04225
type: UnificationXref
id: C04225
db: KEGG Compound

Reference/KEGG Compound C04593
type: UnificationXref
id: C04593
db: KEGG Compound

Reference/ChemSpider 500
type: UnificationXref
id: 500
db: ChemSpider

Methylisocitric acid
type: SmallMolecule
entity reference: Methylisocitric acid

Methylisocitric acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04593
xref: Reference/HMDB HMDB0006471
xref: Reference/ChemSpider 498
xref: Reference/PubChem-compound 513
xref: Reference/ChEBI CHEBI 15607
xref: Reference/BioCyc CPD-618
chemical formula: C7H10O7
molecular weight: 206.04265
structure: ChemicalStructure/PW C002761

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

6.2.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000159/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000988/Stoichiometry/1.0
right: Adenosine monophosphate
right: Pyrophosphate
right: Propionyl-CoA
spontaneous: false
EC number: 6.2.1.1
left: Coenzyme A
left: Propionic acid
left: Adenosine triphosphate
name: Adenosine triphosphate + Coenzyme A + Propionic acid → Adenosine monophosphate + Propionyl-CoA + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Compound/PW C000109 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0