Reference/PubChem-compound 247
type: UnificationXref
id: 247
db: PubChem-compound

autoinducer 2
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 425228
chemical formula: C5H8O4
molecular weight: 132.04225
structure: ChemicalStructure/PW C041012

Reference/CAS 454-29-5
type: UnificationXref
id: 454-29-5
db: CAS

Reference/SMPDB SMP0646205
type: UnificationXref
id: SMP0646205
db: SMPDB

Protein/29092/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/KEGG Compound C05330
type: UnificationXref
id: C05330
db: KEGG Compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000092
type: UnificationXref
id: HMDB0000092
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

βine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 247
xref: Reference/BioCyc BETAINE
xref: Reference/ChemSpider 242
xref: Reference/KEGG Compound C00719
xref: Reference/CAS 107-43-7
xref: Reference/ChEBI CHEBI 17750
xref: Reference/HMDB HMDB0000043
chemical formula: C5H11NO2
molecular weight: 117.07898
structure: ChemicalStructure/PW C000030

Reference/ChEBI CHEBI 20506
type: UnificationXref
id: CHEBI:20506
db: ChEBI

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/ChEBI CHEBI 17230
type: UnificationXref
id: CHEBI:17230
db: ChEBI

Reference/KEGG Compound C00440
type: UnificationXref
id: C00440
db: KEGG Compound

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/PubChem-compound 6137
type: UnificationXref
id: 6137
db: PubChem-compound

Reference/BioCyc 5-METHYL-THF
type: UnificationXref
id: 5-METHYL-THF
db: BioCyc

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 18714427
type: UnificationXref
id: 18714427
db: ChemSpider

Reference/ChemSpider 242
type: UnificationXref
id: 242
db: ChemSpider

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/PathWhiz PW686550
type: UnificationXref
id: PW686550
db: PathWhiz

Reference/ChEBI CHEBI 8968
type: UnificationXref
id: CHEBI:8968
db: ChEBI

Reference/PubChem-compound 49791978
type: UnificationXref
id: 49791978
db: PubChem-compound

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C000548
type: ChemicalStructure
structure format: SMILES
structure data: CSCC[C@H](N)C(O)=O

βine
type: SmallMolecule
entity reference: βine

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Tetrahydrofolic acid
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 20506
xref: Reference/ChemSpider 18714427
xref: Reference/HMDB HMDB0001846
xref: Reference/PubChem-compound 13781857
xref: Reference/BioCyc THF
xref: Reference/CAS 135-16-0
xref: Reference/KEGG Compound C00101
chemical formula: C19H23N7O6
molecular weight: 445.171
structure: ChemicalStructure/PW C001221

Reference/CAS 107-43-7
type: UnificationXref
id: 107-43-7
db: CAS

Reference/PathWhiz PW000837
type: UnificationXref
id: PW000837
db: PathWhiz

4.4.1.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C041012/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000590/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041011/Stoichiometry/1.0
right: Homocysteine
right: autoinducer 2
spontaneous: false
EC number: 4.4.1.21
left: S-ribosyl-L-homocysteine
name: S-ribosyl-L-homocysteine → Homocysteine + autoinducer 2
conversion direction: LEFT_TO_RIGHT

Unknown
type: ProteinReference

2.1.1.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000548/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001079/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001221/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000590/Stoichiometry/1.0
right: Tetrahydrofolic acid
right: L-Methionine
spontaneous: false
EC number: 2.1.1.13
left: 5-Methyltetrahydrofolic acid
left: Homocysteine
name: 5-Methyltetrahydrofolic acid + Homocysteine → L-Methionine + Tetrahydrofolic acid
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc ADENOSYL-HOMO-CYS
type: UnificationXref
id: ADENOSYL-HOMO-CYS
db: BioCyc

Compound/PW C041012/Stoichiometry/1.0
type: Stoichiometry
physical entity: autoinducer 2
stoichiometric coefficient: 1.0

2.5.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000548/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: Pyrophosphate
right: Phosphate
right: S-Adenosylmethionine
spontaneous: false
EC number: 2.5.1.6
left: Water
left: L-Methionine
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Methionine + Water → Phosphate + Pyrophosphate + S-Adenosylmethionine
conversion direction: LEFT_TO_RIGHT

S-Adenosyl-L-Methionine Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway557311
pathway component: SubPathwayInteraction557311
xref: Reference/SMPDB SMP0000857
xref: Reference/PathWhiz PW000837
name: SubPathway

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

3.2.2.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000024/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041011/Stoichiometry/1.0
right: Adenine
right: S-ribosyl-L-homocysteine
spontaneous: false
EC number: 3.2.2.9
left: S-Adenosylhomocysteine
left: Water
name: S-Adenosylhomocysteine + Water → S-ribosyl-L-homocysteine + Adenine
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00101
type: UnificationXref
id: C00101
db: KEGG Compound

Adenine
type: SmallMolecule
entity reference: Adenine

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Adenine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000034
xref: Reference/BioCyc ADENINE
xref: Reference/PubChem-compound 190
xref: Reference/ChemSpider 185
xref: Reference/KEGG Compound C00147
xref: Reference/ChEBI CHEBI 16708
xref: Reference/CAS 73-24-5
chemical formula: C5H5N5
molecular weight: 135.05449
structure: ChemicalStructure/PW C000024

Reference/BioCyc THF
type: UnificationXref
id: THF
db: BioCyc

Compound/PW C000062/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dimethylglycine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15641
type: UnificationXref
id: CHEBI:15641
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Protein/29092/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/CAS 979-92-0
type: UnificationXref
id: 979-92-0
db: CAS

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

S-Adenosylhomocysteine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 25246222
xref: Reference/ChemSpider 388301
xref: Reference/BioCyc ADENOSYL-HOMO-CYS
xref: Reference/CAS 979-92-0
xref: Reference/KEGG Compound C00021
xref: Reference/ChEBI CHEBI 16680
xref: Reference/HMDB HMDB0000939
chemical formula: C14H20N6O5S
molecular weight: 384.12158
structure: ChemicalStructure/PW C000749

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

ChemicalStructure/PW C001221
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000696
type: UnificationXref
id: HMDB0000696
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Compound/PW C001221/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetrahydrofolic acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/SMPDB SMP0000857
type: UnificationXref
id: SMP0000857
db: SMPDB

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

Reference/BioCyc ADENINE
type: UnificationXref
id: ADENINE
db: BioCyc

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/PubChem-compound 673
type: UnificationXref
id: 673
db: PubChem-compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/CAS 135-16-0
type: UnificationXref
id: 135-16-0
db: CAS

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

ChemicalStructure/PW C000024
type: ChemicalStructure
structure format: SMILES
structure data: NC1=C2NC=NC2=NC=N1

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

Compound/PW C000590/Stoichiometry/1.0
type: Stoichiometry
physical entity: Homocysteine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

ChemicalStructure/PW C000590
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCS)C(O)=O

Reference/ChEBI CHEBI 16708
type: UnificationXref
id: CHEBI:16708
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChemSpider 388301
type: UnificationXref
id: 388301
db: ChemSpider

S-Adenosylhomocysteine
type: SmallMolecule
entity reference: S-Adenosylhomocysteine

S-ribosyl-L-homocysteine
type: SmallMolecule
entity reference: S-ribosyl-L-homocysteine

autoinducer 2
type: SmallMolecule
entity reference: autoinducer 2

Reference/KEGG Compound C00021
type: UnificationXref
id: C00021
db: KEGG Compound

Reference/BioCyc MET
type: UnificationXref
id: MET
db: BioCyc

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00147
type: UnificationXref
id: C00147
db: KEGG Compound

Dimethylglycine
type: SmallMolecule
entity reference: Dimethylglycine

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Fusobacterium nucleatum subsp. animalis 3_1_33
type: BioSource
xref: Reference/TAXONOMY 469603

Reference/CAS 1118-68-9
type: UnificationXref
id: 1118-68-9
db: CAS

Reference/CAS 73-24-5
type: UnificationXref
id: 73-24-5
db: CAS

Dimethylglycine
type: SmallMoleculeReference
xref: Reference/BioCyc DIMETHYL-GLYCINE
xref: Reference/ChemSpider 653
xref: Reference/CAS 1118-68-9
xref: Reference/ChEBI CHEBI 17724
xref: Reference/HMDB HMDB0000092
xref: Reference/PubChem-compound 673
xref: Reference/KEGG Compound C01026
chemical formula: C4H9NO2
molecular weight: 103.06333
structure: ChemicalStructure/PW C000062

S-ribosyl-L-homocysteine
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 8968
chemical formula: C9H14NO6S
molecular weight: 264.05417
structure: ChemicalStructure/PW C041011

Compound/PW C041011/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-ribosyl-L-homocysteine
stoichiometric coefficient: 1.0

SubPathwayInteraction557311
type: Interaction
name: SubPathway557311Reaction
name: SubPathwayReaction
participant: S-Adenosylmethionine

L-Methionine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000696
xref: Reference/ChEBI CHEBI 16643
xref: Reference/KEGG Compound C00073
xref: Reference/CAS 63-68-3
xref: Reference/BioCyc MET
xref: Reference/PubChem-compound 6137
xref: Reference/ChemSpider 5907
chemical formula: C5H11NO2S
molecular weight: 149.05106
structure: ChemicalStructure/PW C000548

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/ChemSpider 653
type: UnificationXref
id: 653
db: ChemSpider

Water
type: SmallMolecule
entity reference: Water

Compound/PW C000024/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenine
stoichiometric coefficient: 1.0

Reference/TAXONOMY 469603
type: UnificationXref
id: 469603
db: TAXONOMY

Reference/KEGG Compound C00719
type: UnificationXref
id: C00719
db: KEGG Compound

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/ChEBI CHEBI 17750
type: UnificationXref
id: CHEBI:17750
db: ChEBI

S-Adenosylmethionine
type: SmallMolecule
cellular location: Cytosol
entity reference: S-Adenosylmethionine
name: SubPathwayOutput

Reference/HMDB HMDB0000939
type: UnificationXref
id: HMDB0000939
db: HMDB

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000062
type: ChemicalStructure
structure format: SMILES
structure data: CN(C)CC(O)=O

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChEBI CHEBI 17724
type: UnificationXref
id: CHEBI:17724
db: ChEBI

S-Adenosyl-L-Methionine Cycle
type: Pathway
pathway order: PathwayEnzymeReaction/7260607
pathway order: PathwaySubPathway/557311
pathway order: PathwayEnzymeReaction/7260611
pathway order: PathwayEnzymeReaction/7260604
pathway order: PathwayEnzymeReaction/7260614
pathway order: PathwayEnzymeReaction/7260601
pathway component: 4.4.1.21
pathway component: ReactionCatalysis1437292
pathway component: 2.1.1.13
pathway component: Reaction3066
pathway component: ReactionCatalysis1437290
pathway component: 2.5.1.6
pathway component: S-Adenosyl-L-Methionine Biosynthesis
pathway component: ReactionCatalysis1437297
pathway component: 3.2.2.9
pathway component: ReactionCatalysis1437294
xref: Reference/SMPDB SMP0646205
xref: Reference/PathWhiz PW686550
organism: Fusobacterium nucleatum subsp. animalis 3_1_33

Unknown
type: Protein
entity reference: Unknown

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Reference/KEGG Compound C01026
type: UnificationXref
id: C01026
db: KEGG Compound

Reference/HMDB HMDB0000034
type: UnificationXref
id: HMDB0000034
db: HMDB

ChemicalStructure/PW C000030
type: ChemicalStructure
structure format: SMILES
structure data: C[N+](C)(C)CC([O-])=O

Compound/PW C001079/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5-Methyltetrahydrofolic acid
stoichiometric coefficient: 1.0

Compound/PW C000030/Stoichiometry/1.0
type: Stoichiometry
physical entity: βine
stoichiometric coefficient: 1.0

Reference/CAS 63-68-3
type: UnificationXref
id: 63-68-3
db: CAS

Reference/ChemSpider 5907
type: UnificationXref
id: 5907
db: ChemSpider

Reference/ChEBI CHEBI 16643
type: UnificationXref
id: CHEBI:16643
db: ChEBI

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

L-Methionine
type: SmallMolecule
entity reference: L-Methionine

5-Methyltetrahydrofolic acid
type: SmallMolecule
entity reference: 5-Methyltetrahydrofolic acid

Compound/PW C000548/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Methionine
stoichiometric coefficient: 1.0

5-Methyltetrahydrofolic acid
type: SmallMoleculeReference
xref: Reference/BioCyc 5-METHYL-THF
xref: Reference/ChEBI CHEBI 15641
xref: Reference/PubChem-compound 439234
xref: Reference/CAS 134-35-0
xref: Reference/KEGG Compound C00440
xref: Reference/ChemSpider 388371
xref: Reference/HMDB HMDB0001396
chemical formula: C20H25N7O6
molecular weight: 459.18665
structure: ChemicalStructure/PW C001079

Reference/KEGG Compound C00073
type: UnificationXref
id: C00073
db: KEGG Compound

Reference/HMDB HMDB0000043
type: UnificationXref
id: HMDB0000043
db: HMDB

Reference/BioCyc DIMETHYL-GLYCINE
type: UnificationXref
id: DIMETHYL-GLYCINE
db: BioCyc

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/PubChem-compound 439234
type: UnificationXref
id: 439234
db: PubChem-compound

Tetrahydrofolic acid
type: SmallMolecule
entity reference: Tetrahydrofolic acid

Reference/BioCyc BETAINE
type: UnificationXref
id: BETAINE
db: BioCyc

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Homocysteine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05330
xref: Reference/CAS 454-29-5
xref: Reference/HMDB HMDB0000742
xref: Reference/ChEBI CHEBI 17230
xref: Reference/ChemSpider 757
xref: Reference/PubChem-compound 49791978
xref: Reference/BioCyc HOMO-CYS
chemical formula: C4H9NO2S
molecular weight: 135.0354
structure: ChemicalStructure/PW C000590

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Reference/BioCyc HOMO-CYS
type: UnificationXref
id: HOMO-CYS
db: BioCyc

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reaction3066
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000749/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000030/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000062/Stoichiometry/1.0
right: βine
right: S-Adenosylhomocysteine
right: Hydrogen Ion
spontaneous: false
left: Dimethylglycine
left: S-Adenosylmethionine
name: Dimethylglycine + S-Adenosylmethionine → Hydrogen Ion + S-Adenosylhomocysteine + βine
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000742
type: UnificationXref
id: HMDB0000742
db: HMDB

ChemicalStructure/PW C001079
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C041012
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(=O)C(O)CO

ChemicalStructure/PW C041011
type: ChemicalStructure
structure format: SMILES
structure data: [N+]C(CCSCC1OC(O)C(O)C1O)C([O-])=O

Reference/HMDB HMDB0001396
type: UnificationXref
id: HMDB0001396
db: HMDB

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
type: Complex
component stoichiometry: Protein/29092/Stoichiometry/2.0
component: Unknown

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 388371
type: UnificationXref
id: 388371
db: ChemSpider

ChemicalStructure/PW C000749
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 757
type: UnificationXref
id: 757
db: ChemSpider

Reference/PubChem-compound 25246222
type: UnificationXref
id: 25246222
db: PubChem-compound

Homocysteine
type: SmallMolecule
entity reference: Homocysteine

Compound/PW C000749/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylhomocysteine
stoichiometric coefficient: 1.0

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/PubChem-compound 190
type: UnificationXref
id: 190
db: PubChem-compound

Reference/ChEBI CHEBI 425228
type: UnificationXref
id: CHEBI:425228
db: ChEBI

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

methionine adenosyltransferase
type: Complex
component stoichiometry: Protein/29092/Stoichiometry/4.0
component: Unknown

Reference/HMDB HMDB0001846
type: UnificationXref
id: HMDB0001846
db: HMDB

Reference/ChEBI CHEBI 16680
type: UnificationXref
id: CHEBI:16680
db: ChEBI

ReactionCatalysis1437297
type: Catalysis
controller: methionine adenosyltransferase
controlled: 2.5.1.6
control type: ACTIVATION

ReactionCatalysis1437294
type: Catalysis
controller: Unknown
controlled: 2.1.1.13
control type: ACTIVATION

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

ReactionCatalysis1437292
type: Catalysis
controller: Unknown
controlled: 4.4.1.21
control type: ACTIVATION

ReactionCatalysis1437290
type: Catalysis
controller: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
controlled: 3.2.2.9
control type: ACTIVATION

Reference/ChemSpider 185
type: UnificationXref
id: 185
db: ChemSpider

Reference/CAS 134-35-0
type: UnificationXref
id: 134-35-0
db: CAS

Reference/PubChem-compound 13781857
type: UnificationXref
id: 13781857
db: PubChem-compound