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Pathway Description
Brassinosteroid Synthesis
Arabidopsis thaliana
Metabolic Pathway
Brassinosteroids are plant hormones used in many processes including growth, immunity and the development of plants. This pathway depicts brassinosteroid synthesis in a cell from the species Arabidopsis thaliana, or mouse-ear cress. This species in particular has provided recent insight on brassinosteroid’s role in plant growth through molecular genetics. The pathway begins with campesterol, a compound created through steroid biosynthesis. As brassinosteroid synthesis moves along, compounds react inter-connectedly with many different proteins, to finally create 26-hydroxybrassinolide. Some of the proteins commonly used in this pathway include cytochrome P450 90B1, cytochrome P450 90D2, cytochrome P450 85A2 and 3-epi-6-deoxocathasterone 23-monooxygenase CYP90D1. These proteins are found in various locations throughout the plant cell, such as the membrane, the endoplasmic reticulum, and the mitochondrial matrix. The proteins that a dark green indicate reactions taking place in the plasma membrane.
References
Brassinosteroid Synthesis References
Ohnishi T: Recent advances in brassinosteroid biosynthetic pathway: insight into novel brassinosteroid shortcut pathway. J Pestic Sci. 2018 Aug 20;43(3):159-167. doi: 10.1584/jpestics.D18-040.
Pubmed: 30363110
Noguchi T, Fujioka S, Choe S, Takatsuto S, Tax FE, Yoshida S, Feldmann KA: Biosynthetic pathways of brassinolide in Arabidopsis. Plant Physiol. 2000 Sep;124(1):201-9. doi: 10.1104/pp.124.1.201.
Pubmed: 10982435
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