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PathWhiz ID Pathway Meta Data

PW358580

Pw358580 View Pathway
metabolic

Ribose Degradation

Escherichia coli 536
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: November 13, 2024 at 16:05

Last Updated: November 13, 2024 at 16:05

PW358600

Pw358600 View Pathway
metabolic

Ribose Degradation

Escherichia coli O26:H11 str. 11368
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: November 13, 2024 at 16:12

Last Updated: November 13, 2024 at 16:12

PW358597

Pw358597 View Pathway
metabolic

Ribose Degradation

Escherichia coli O157:H7 str. TW14359
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: November 13, 2024 at 16:11

Last Updated: November 13, 2024 at 16:11

PW340549

Pw340549 View Pathway
metabolic

Ribose Degradation

Bacteroides oleiciplenus YIT 12058
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: October 30, 2024 at 16:51

Last Updated: October 30, 2024 at 16:51

PW340823

Pw340823 View Pathway
metabolic

Ribose Degradation

Lautropia mirabilis ATCC 51599
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: October 30, 2024 at 20:04

Last Updated: October 30, 2024 at 20:04

PW340936

Pw340936 View Pathway
metabolic

Ribose Degradation

Citrobacter amalonaticus Y19
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: October 30, 2024 at 21:32

Last Updated: October 30, 2024 at 21:32

PW340900

Pw340900 View Pathway
metabolic

Ribose Degradation

Campylobacter upsaliensis JV21
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: October 30, 2024 at 21:03

Last Updated: October 30, 2024 at 21:03

PW341035

Pw341035 View Pathway
metabolic

Ribose Degradation

Acinetobacter johnsonii SH046
Escherichia coli can utilize the monosaccharide D-ribose as the sole source of carbon and energy for the cell. A high-affinity ABC transport system transports D-ribose into the cell as unphosphorylated beta-D-ribopyranose. Ribose pyranase converts between the furanose and pyranose forms of beta-D-ribose. D-ribofuranose converts between the alpha and beta anomers quickly and spontaneously. Ribokinase converts D-ribose to the pentose phosphate pathway intermediate, D-ribose 5-phosphate, which can enter the central metabolism pathways to meet the cells needs.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Julia Wakoli

Created On: October 30, 2024 at 22:45

Last Updated: October 30, 2024 at 22:45

PW127219

Pw127219 View Pathway
disease

Ribose-5-phosphate Isomerase Deficiency

Homo sapiens
Ribose-5-phosphate isomerase (RPI) deficiency, is a genetic disorder caused by mutations in the RPIA gene that codes for RPI. RPI is an enzyme that is involved in the pentose phosphate pathway as part of carbohydrate degradation. It reversibly converts D-ribulose 5-phosphate into D-ribose 5-phosphate. In the case of this disorder, RPI functions partially in tissues, because if the gene was simply non-functional, it would likely be lethal. This means that a specific type of mutation needs to occur for this disorder to occur, leading to it being the rarest disease in the world, with only three confirmed cases. In the first known case, the patient had one allele containing a frameshift mutation, which led to a truncated protein, while the other allele contained a missense mutation. This combination meant that activity of RPI was found to vary across tissues and cell types. Characteristics of the RPI deficiency include higher ribitol and arabitol levels in a metabolic profile, as well as differences in polyol profiles. There are other symptoms, including leukoencephalopathy and neuropathy, which may be caused by a toxic accumulation of ribitol and arabitol, or a potential lack of ribose-5-phosphate in RNA synthesis.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ray Kruger

Created On: November 14, 2022 at 09:55

Last Updated: November 14, 2022 at 09:55

PW122064

Pw122064 View Pathway
disease

Ribose-5-phosphate Isomerase Deficiency

Rattus norvegicus
Ribose-5-phosphate isomerase (RPI) deficiency, is a genetic disorder caused by mutations in the RPIA gene that codes for RPI. RPI is an enzyme that is involved in the pentose phosphate pathway as part of carbohydrate degradation. It reversibly converts D-ribulose 5-phosphate into D-ribose 5-phosphate. In the case of this disorder, RPI functions partially in tissues, because if the gene was simply non-functional, it would likely be lethal. This means that a specific type of mutation needs to occur for this disorder to occur, leading to it being the rarest disease in the world, with only three confirmed cases. In the first known case, the patient had one allele containing a frameshift mutation, which led to a truncated protein, while the other allele contained a missense mutation. This combination meant that activity of RPI was found to vary across tissues and cell types. Characteristics of the RPI deficiency include higher ribitol and arabitol levels in a metabolic profile, as well as differences in polyol profiles. There are other symptoms, including leukoencephalopathy and neuropathy, which may be caused by a toxic accumulation of ribitol and arabitol, or a potential lack of ribose-5-phosphate in RNA synthesis.
BioPAX SVG SBGN SBML PWML All files (.zip)

Creator: Ana Marcu

Created On: September 10, 2018 at 15:52

Last Updated: September 10, 2018 at 15:52