PathWhiz

PathWhiz ID	Pathway	Meta Data
PW124446 View Pathway	metabolic TCA Cycle - Pract Escherichia coli (strain K12) The name of this metabolic pathway is derived from the citric acid (a tricarboxylic acid, often called citrate, as the ionized form predominates at biological pH[6]) that is consumed and then regenerated by this sequence of reactions to complete the cycle. The cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, releasing carbon dioxide. The NADH generated by the citric acid cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: January 13, 2021 at 12:49 Last Updated: January 13, 2021 at 12:49
PW124448 View Pathway	metabolic TCA Cycle - Practi Escherichia coli The citric acid cycle (CAC) – also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: January 13, 2021 at 13:19 Last Updated: January 13, 2021 at 13:19
PW012856 View Pathway	metabolic TCA Cycle - Practice Escherichia coli (strain K12) The citric acid cycle, which is also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle, is a collection of 9 enzyme-catalyzed chemical reactions that occurs in all living cells undergoing aerobic respiration. The citric acid cycle itself was officially identified in 1937 by Hans Adolf Krebs, who received the Nobel Prize for this discovery in 1953. In eukaryotes, the citric acid cycle occurs in the mitochondria. In prokaryotes, the TCA cycle occurs in the cytoplasm. The TCA cycle starts with acetyl-CoA, which is the “fuel” for the entire cycle. This important molecule is formed from the breakdown of glycogen (a stored form of glucose), fats, and many amino acids. At the start of the cycle, acetyl-CoA first transfers its 2-carbon acetyl group to the 4-carbon acceptor compound called oxaloacetate to form the 6-carbon compound (citrate) for which the cycle is named. The resulting citrate molecule then goes through a series of chemical transformations, whereby it loses one carboxyl group (leading to the 5-carbon compound called alpha-ketoglutarate) and then a second carboxyl group (leading to the 4-carbon compound called succinate). Succinate molecule is further oxidized to fumarate, then malate and finally oxaloacetate. The regeneration of the 4-carbon oxaloacetate, allows the TCA cycle to continue. Most of the energy generated by the oxidation steps in the TCA cycle is transferred as energy-rich electrons to NAD+, forming NADH. For each acetyl group that enters the citric acid cycle, three molecules of NADH are produced. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 24, 2016 at 10:40 Last Updated: October 24, 2016 at 10:40
PW124450 View Pathway	metabolic TCA Cycle 111 Escherichia coli (strain K12) also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: January 13, 2021 at 13:30 Last Updated: January 13, 2021 at 13:30
PW126068 View Pathway	metabolic TCA Cycle 1623208891 Saccharomyces cerevisiae BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Luis Fernando González Rico Created On: June 08, 2021 at 21:22 Last Updated: June 08, 2021 at 21:22
PW002768 View Pathway	metabolic TCA Cycle 2 Mycobacterium marinum TCA and ETC BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: July 17, 2016 at 20:27 Last Updated: July 17, 2016 at 20:27
PW012854 View Pathway	metabolic TCA cycle Replica Escherichia coli This is the TCA Cycle for E coli. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 21, 2016 at 18:48 Last Updated: October 21, 2016 at 18:48
PW012851 View Pathway	metabolic TCA cycle test replicate Escherichia coli TCA Cycle Replicated - An important pathway in e coli... BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 19, 2016 at 13:42 Last Updated: October 19, 2016 at 13:42
PW002523 View Pathway	metabolic TCA cycle with mistakes Escherichia coli BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: April 13, 2016 at 10:18 Last Updated: April 13, 2016 at 10:18
PW124452 View Pathway	metabolic TCA Cycle-13 Escherichia coli (strain K12) also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: January 13, 2021 at 14:04 Last Updated: January 13, 2021 at 14:04