PathWhiz

PathWhiz ID	Pathway	Meta Data
PW126958 View Pathway	metabolic triterpenoid biosynthesis Camellia nitidissima BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ping Created On: May 25, 2022 at 18:41 Last Updated: May 25, 2022 at 18:41
PW146669 View Pathway	drug action Tritoqualine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:45 Last Updated: October 07, 2023 at 18:45
PW063854 View Pathway	drug action Tritoqualine H1-Antihistamine Action Homo sapiens Tritoqualine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the activity of the NF-κB immune response transcription factor through the phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause sedation and other adverse central nervous system (CNS) effects (e.g. nervousness and insomnia). Second-generation antihistamines are more selective for H1-receptors of the peripheral nervous system (PNS) and do not cross the blood-brain barrier. Consequently, these newer drugs elicit fewer adverse drug reactions. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Carin Li Created On: September 24, 2017 at 23:27 Last Updated: September 24, 2017 at 23:27
PW404546 View Pathway	metabolic tRNA Charging Escherichia coli 042 This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 21, 2024 at 02:07 Last Updated: December 21, 2024 at 02:07
PW402502 View Pathway	metabolic tRNA Charging Escherichia coli DORA_B_14 This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 20, 2024 at 12:25 Last Updated: December 20, 2024 at 12:25
PW402603 View Pathway	metabolic tRNA Charging Escherichia coli K-12 This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 20, 2024 at 13:12 Last Updated: December 20, 2024 at 13:12
PW404577 View Pathway	metabolic tRNA Charging Escherichia coli IHE3034 This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 21, 2024 at 02:24 Last Updated: December 21, 2024 at 02:24
PW406768 View Pathway	metabolic tRNA Charging Escherichia coli (strain 55989 / EAEC) This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 22, 2024 at 16:09 Last Updated: December 22, 2024 at 16:09
PW406720 View Pathway	metabolic tRNA Charging Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: December 22, 2024 at 15:37 Last Updated: December 22, 2024 at 15:37
PW000799 View Pathway	metabolic tRNA Charging Escherichia coli This pathway is a compilation of Escherichia coli tRNA charging reactions involving amino acids transported into the cell. The aminoacyl-tRNA synthetase is an enzyme that attaches the appropriate amino acid onto its tRNA by catalyzing the esterification of a specific cognate amino acid or its precursor to one of all its compatible cognate tRNAs to form an aminoacyl-tRNA, which plays an important role in RNA translation. 20 different Aminoacyl-tRNA synthetases can make 20 different types of aa-tRNA for each amino acid according to the genetic code. This process is called "charging" or "loading" the tRNA with amino acid. Ribosome can transfer the amino acid from tRNA to a growing peptide after the tRNA is charged. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: March 09, 2015 at 23:49 Last Updated: March 09, 2015 at 23:49