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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517624 results

SMP0000098

Pw000139 View Pathway
Metabolite

Ketorolac Action Pathway

Homo sapiens

  • Matched Description: relieve pain (analgesic), reduce fever (antipyretic) and swelling. Ketorolac can block prostaglandin … synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H … synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 … process of inflammation; hence, inhibition of prostaglandin synthesis can reduce the pain, fever and inflammation.

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000102

    Pw000259 View Pathway
    Metabolite

    Bromfenac Action Pathway

    Homo sapiens

  • Matched Description: ). It can be used to reduce ocular inflammation and pain after cataract surgery. Bromfenac is also a … action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 … catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000109

    Pw000261 View Pathway
    Metabolite

    Mefenamic Acid Action Pathway

    Homo sapiens

  • Matched Description: used to relieve pain (analgesic) and reduce fever (antipyretic). Mefenamic acid can block prostaglandin … synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H … synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 … process of inflammation; hence, inhibition of prostaglandin synthesis can reduce the pain, fever and inflammation.

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000075

    Pw000044 View Pathway
    Metabolite

    Arachidonic Acid Metabolism

    Homo sapiens

  • Matched Description: This pathway describes the production and subsequent metabolism of arachidonic acid, an omega-6 … phosphatidylethanolamine and phosphatidylcholine) of membranes of the body’s cells, and is particularly abundant … phospholipid hydrolysis and releases the fatty acid into the intracellular medium. Three enzymes … mediate this deacylation reaction including phospholipase A2 (PLA2), phospholipase C (PLC), and … phospholipids, 2) diffusion outside the cell, and 3) metabolism. Arachidonate metabolism is carried out

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Metabolic

    SMP0000096

    Pw000138 View Pathway
    Metabolite

    Celecoxib metabolism Pathway

    Homo sapiens

  • Matched Description: effects by inhibiting the synthesis of prostaglandins involved in pain, fever and inflammation. COX-2 … catalyzes the conversion of arachidonic acid to prostaglandin G2 (PGE2) and PGE2 to prostaglandin H2 … (PGH2). In the COX-2 catalyzed pathway, PGH2 is the precusor of prostaglandin E2 (PGE2) and I2 … (PGI2). PGE2 induces pain, fever, erythema and edema. Celecoxib antagonizes COX-2 by binding to the … site. Similar to other COX-2 inhibitors, such as rofecoxib and valdecoxib, celecoxib appears to

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Metabolic

    SMP0000692

    Pw000669 View Pathway
    Metabolite

    Antipyrine Action Pathway

    Homo sapiens

  • Matched Description: of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze … the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000694

    Pw000671 View Pathway
    Metabolite

    Carprofen Action Pathway

    Homo sapiens

  • Matched Description: of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the … arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000699

    Pw000676 View Pathway
    Metabolite

    Lumiracoxib Action Pathway

    Homo sapiens

  • Matched Description: synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H … synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000706

    Pw000683 View Pathway
    Metabolite

    Tenoxicam Action Pathway

    Homo sapiens

  • Matched Description: Tenoxicam (also named mobiflex and tilcotil) is a nonsteroidal anti-inflammatory drug (NSAID). It … can be used to reduce inflammation, swelling, stiffness, and pain that are associated with various … diseases such as tendinitis, bursitis and etc. Tenoxicam can block prostaglandin synthesis by the … action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze … the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000101

    Pw000258 View Pathway
    Metabolite

    Suprofen Action Pathway

    Homo sapiens

  • Matched Description: Suprofen (also named Profenal and Maldocil) is a nonsteroidal anti-inflammatory drug (NSAID). It … can be used to relieve pain (analgesic) and reduce fever (antipyretic). Suprofen is also a type of … /H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to … prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. Since … prostaglandin synthesis can reduce the pain and inflammation (e.g. in the eyes).

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action