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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517624 results

SMP0000705

Pw000682 View Pathway
Metabolite

Tiaprofenic Acid Action Pathway

Homo sapiens

  • Matched Description: Tiaprofenic Acid (also named tiaprofensaeure and surgam) is a nonsteroidal anti-inflammatory drug … prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H … synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000710

    Pw000687 View Pathway
    Metabolite

    Acetaminophen Action Pathway

    Homo sapiens

  • Matched Description: (NSAIDs). However, it still can be used to treat pain and fever. Acetaminophen can block prostaglandin … synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase … 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000083

    Pw000128 View Pathway
    Metabolite

    Acetylsalicylic Acid Action Pathway

    Homo sapiens

  • Matched Description: acts as an analgesic, antipyretic and antithrombotic agent. Like most other NSAIDs, aspirin exerts … its therapeutic effects by inhibiting prostaglandin G/H synthase 1 and 2, better known as … cyclooxygenase-1 and -2 or simply COX-1 and -2. COX-1 and -2 catalyze the conversion of arachidonic acid to … prostaglandin G2 and prostaglandin G2 to prostaglandin H2. Prostaglandin H2 is the precursor to a … number of other prostaglandins, such as prostaglandin E2, involved in pain, fever and inflammation. The

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000085

    Pw000130 View Pathway
    Metabolite

    Ketoprofen Action Pathway

    Homo sapiens

  • Matched Description: -inflammatory drug (NSAID). It can be used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to … of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic … acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism … , increased peripheral blood flow and subsequent heat dissipation.

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000093

    Pw000135 View Pathway
    Metabolite

    Diclofenac Action Pathway

    Homo sapiens

  • Matched Description: to treat prostaglandin G/H synthase related fever, swelling, pain and inflammation. Diclofenac can … block prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2 … . Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000113

    Pw000262 View Pathway
    Metabolite

    Oxaprozin Action Pathway

    Homo sapiens

  • Matched Description: used to relieve pain (analgesic) and reduce fever (antipyretic). Oxaprozin is also a type of … synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2 … , and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. Since … prostaglandin is the messenger molecules in the process of inflammation; hence, inhibition of prostaglandin synthesis can reduce the pain and inflammation.

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000696

    Pw000673 View Pathway
    Metabolite

    Fenoprofen Action Pathway

    Homo sapiens

  • Matched Description: prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin … G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000701

    Pw000678 View Pathway
    Metabolite

    Phenylbutazone Action Pathway

    Homo sapiens

  • Matched Description: -inflammatory drug (NSAID). It can be used to treat the pain and fever in animal. However, Phenylbutazone is not … approved in United State and United Kingdom for human use anymore because of severe adverse effects … synthase 1 and 2. Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin … G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway. Decreased

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000703

    Pw000680 View Pathway
    Metabolite

    Trisalicylate-Choline Action Pathway

    Homo sapiens

  • Matched Description: -inflammatory drug (NSAID). It can be used to treat pain and fever. Trisalicylate-Choline can block … prostaglandin synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H … synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action

    SMP0000708

    Pw000685 View Pathway
    Metabolite

    Salicylate-Sodium Action Pathway

    Homo sapiens

  • Matched Description: ). It can be used for relieving pain and reducing fever. Salicylate-sodium can block prostaglandin … synthesis by the action of inhibition of prostaglandin G/H synthase 1 and 2. Prostaglandin G/H synthase 1 … and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to

  • Matched Compounds: 20-Hydroxy-leukotriene B4 … 20-Carboxy-leukotriene B4 … 20-Hydroxyeicosatetraenoic acid … PC(14:0/20:4(5Z,8Z,11Z,14Z))

  • Matched Protein Synonyms: Leukotriene-B(4) 20-monooxygenase 1 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20 … Cytochrome P450 MP-20

  • Matched Compound Synonyms: 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoate … 20-oh-ltb4 … 20-oh-5s,12s-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid … 20-oh-leukotriene b4 … 20-hydroxy arachidonic acid

    • BioPAX SVG SBGN SBML PWML All files (.zip)

    Drug Action