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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 517624 results

SMP0000155 View Pathway	Metabolite Rescinnamine Action Pathway Homo sapiens Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive angiotensin … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Benazepril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and … increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000163 View Pathway	Metabolite Olmesartan Action Pathway Homo sapiens Matched Description: effects of aldosterone on electrolyte and water excretion, refer to the description of the \spironolactone … prevent increasing sodium, water reabsorption and peripheral resistance (that will lead to increasing … blood pressure) via aldosterone secretion that is caused by angiotensin II. Therefore, action of … /pathways/SMP00132/pathway pathway, which describes the mechanism of direct aldosterone antagonists … . Olmesartan is an effective agent for reducing blood pressure and may be used to treat essential hypertension and heart failure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0127070 View Pathway	Metabolite ACE Mus musculus Matched Description: are degradation of bradykinin, substance P, and amyloid beta-protein. Angiotensin converting enzyme … (ACE) is well known for its dual actions in converting inactive Ang I to active Ang II and degrade … bottle neck step is the production of pressor Ang II, this was targeted pharmacologically in 1970s and … of an epidemic in 2002–2003. Two isozymes of ACE are present in mammals: somatic ACE and testis ACE … . Somatic ACE possesses two catalytic domains (N- and C-domains) and a C-terminal transmembrane Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Physiological
SMP0127072 View Pathway	Metabolite ACE Bos taurus Matched Description: are degradation of bradykinin, substance P, and amyloid beta-protein. Angiotensin converting enzyme … (ACE) is well known for its dual actions in converting inactive Ang I to active Ang II and degrade … bottle neck step is the production of pressor Ang II, this was targeted pharmacologically in 1970s and … of an epidemic in 2002–2003. Two isozymes of ACE are present in mammals: somatic ACE and testis ACE … . Somatic ACE possesses two catalytic domains (N- and C-domains) and a C-terminal transmembrane Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Physiological
SMP0000447 View Pathway	Metabolite Cyclophosphamide Action Pathway Homo sapiens Matched Description: isozymes in the liver. 4-Hydroxyphosphamide is more soluble than cyclophosphamide and is the primary form … cancer cell and spontaneuosly forms aldophosphamide. This is a reversible reaction. Aldophosphamide can … decompose into acrolein and phosphoramide mustard. Phosphoramide mustard is the active alkylating … agent and forms alkyl adducts with DNA through a phosphoramide aziridinium intermediate. Alkylation … of DNA causes DNA damage and eventually cell death. Matched Protein Synonyms: Cytochrome P450 MP-20 Matched Compound Synonyms: Magnacide h and b … [oh(oh)] BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000145 View Pathway	Metabolite Benazepril Action Pathway Homo sapiens Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug … can also be used in the treatment of congestive heart failure and type II diabetes. Benazepril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and … increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000150 View Pathway	Metabolite Lisinopril Action Pathway Homo sapiens Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive angiotensin … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Benazepril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and … increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000152 View Pathway	Metabolite Perindopril Action Pathway Homo sapiens Matched Description: component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive angiotensin … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Benazepril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and … increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000157 View Pathway	Metabolite Trandolapril Action Pathway Homo sapiens Matched Description: ) is a component of the body's renin–angiotensin–aldosterone system (RAAS) and cleaves inactive … enzyme (ACE) inhibitors and is used primarily to lower high blood pressure (hypertension). This drug can … also be used in the treatment of congestive heart failure and type II diabetes. Trandolapril is a … vasodilator bradykinin. Consequently, ACE inhibitors decrease angiotensin II concentrations and … increase bradykinin concentrations resulting in blood vessel dilation and thereby lowering blood pressure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action
SMP0000158 View Pathway	Metabolite Candesartan Action Pathway Homo sapiens Matched Description: the effects of aldosterone on electrolyte and water excretion, refer to the description of the … .) to prevent increasing sodium, water reabsorption and peripheral resistance (that will lead to … increasing blood pressure) via aldosterone secretion that is caused by angiotensin II. Therefore … spironolactone or triamterene pathways, which describes the mechanism of direct aldosterone antagonists … . Candesartan is an effective agent for reducing blood pressure and may be used to treat essential hypertension and heart failure. Matched Compounds: Aldosterone Matched Compound Synonyms: (+)-aldosterone … D-aldosterone … Delta-aldosterone … Aldosterone BioPAX SVG SBGN SBML PWML All files (.zip) Drug Action