SMP0000695
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Etoricoxib Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000700
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Lornoxicam Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000707
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Salsalate Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000098
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Ketorolac Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000102
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Bromfenac Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000109
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Mefenamic Acid Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000083
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Acetylsalicylic Acid Action Pathway
Homo sapiens
Matched Description: inhibited for the lifetime of the platelet (approximately 8 – 12 days). Aspirin is commonly used at low
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000085
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Ketoprofen Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000093
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Diclofenac Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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SMP0000113
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Oxaprozin Action Pathway
Homo sapiens
Matched Compounds: 12-Keto-leukotriene B4 … δ-12-Prostaglandin J2 … 12(R)-HPETE … 12(S)-HPETE … 12(R)-HETE
Matched Proteins: Arachidonate 12-lipoxygenase, 12R-type … Arachidonate 12-lipoxygenase, 12S-type
Matched Protein Synonyms: p53-induced gene 12 protein … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12 … Cytochrome P450 MP-12
Matched Compound Synonyms: 5(s),12(r)-dihydroxy-20-carboxy-6,8,10,14-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoic acid … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-eicosatetraenoate … 5(s),12(r)-dihydroxy-6(z),8(e),10(e),14(z)-icosatetraenoate
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