SMP0127693
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Gs Serotonergic Smooth Muscle Contraction
Mus musculus
Matched Proteins: Inositol 1,4,5-trisphosphate receptor type 1 … Adenylate cyclase type 1 … Voltage-dependent L-type calcium channel subunit beta-1
Matched Protein Synonyms: Tissue-specific extinguisher 1 … Tissue-specific extinguisher 1 … Calcium channel voltage-dependent subunit beta 1 … Tissue-specific extinguisher 1
Matched Compound Synonyms: Potassium ion(1+) … Potassium(1+) ion … Potassium(1+) … Potassium ion(1+) … Potassium(1+) ion
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SMP0125902
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Tenofovir Disoproxil Action Pathway
Homo sapiens
Matched Description: Hepatitis B infection and used to manage HIV-1 infection. This drug prevents viral DNA chain … elongation through inhibition of enzymes necessary for host cell infection viral replication in HIV-1 and … diphosphate inhibits HIV-1 reverse transcriptase and the Hepatitis B polymerase by direct binding in
Matched Proteins: Adenylate kinase isoenzyme 1
Matched Protein Synonyms: AK 1 … ATP-AMP transphosphorylase 1 … Organic anion transporter 1 … Renal organic anion transporter 1
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SMP0125914
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Cabotegravir Action Pathway
Homo sapiens
Matched Description: Cabotegravir is an HIV-1 integrase inhibitor used for treatment and pre-exposure prophylaxis of HIV … -1 infection. It is prescribed with the non-nucleoside reverse transcriptase inhibitor, rilpivirine
Matched Proteins: Importin subunit beta-1
Matched Protein Synonyms: Organic anion transporter 1 … Renal organic anion transporter 1 … RAG cohort protein 1 … Karyopherin subunit beta-1
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SMP0126331
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Methsuximide Action Pathway
Homo sapiens
Matched Proteins: Glutamate decarboxylase 1 … Adenylate cyclase type 1 … Gamma-aminobutyric acid type B receptor subunit 1
Matched Protein Synonyms: ATP pyrophosphate-lyase 1 … Adenylyl cyclase 1 … Solute carrier family 32 member 1 … Calcium channel, L type, alpha-1 polypeptide isoform 4
Matched Compound Synonyms: 1-amino-propane-1,3-dicarboxylate … 1-amino-propane-1,3-dicarboxylic acid … 1-aminopropane-1,3-dicarboxylate … 1-aminopropane-1,3-dicarboxylic acid … Chloride(1-)
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SMP0126353
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Atomoxetine Action Pathway (New)
Homo sapiens
Matched Proteins: Voltage-dependent L-type calcium channel subunit beta-1 … Beta-1 adrenergic receptor
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 4 … Calcium channel voltage-dependent subunit beta 1 … Beta-1 adrenoceptor … Beta-1 adrenoreceptor
Matched Compound Synonyms: (r)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … 4-[(1r)-2-amino-1-hydroxyethyl]-1,2-benzenediol … 4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … L-2-amino-1-(3,4-dihydroxyphenyl)ethanol … 1-dehydroascorbate
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SMP0145411
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Mirtazapine H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
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SMP0145416
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Diphenhydramine H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
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SMP0145423
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Doxepin H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
Matched Compound Synonyms: 3-dibenz[b,e]oxepin-11(6h)-ylidene-n,n-dimethyl-1-propanamine … 3-dibenz[b,e]oxepin-11(6h)-ylidene-n,n-dimethyl-1-propanamine … 3-dibenz[b,e]oxepin-11(6h)-ylidene-n,n-dimethyl-1-propanamine
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SMP0145428
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Esmirtazapine H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
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SMP0145431
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Trimipramine H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
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