SMP0000018
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Alpha Linolenic Acid and Linoleic Acid Metabolism
Homo sapiens
Matched Description: )-desaturase (delta-5-desaturase/fatty acid desaturase 1). Arachidonic acid is then converted to a series of
Matched Proteins: Fatty acid desaturase 1
Matched Protein Synonyms: Fatty acid elongase 1 … Fatty acid elongase 1 … Fatty acid elongase 1 … Fatty acid elongase 1
Matched Compound Synonyms: Phosphatidylcholine (1-18:3-2-18:2) … 1-a-linolenoyl-2-linoleoyl-sn-glycero-3-phosphocholine … 1-alpha-linolenoyl-2-linoleoyl-sn-glycero-3-phosphocholine
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SMP0000313
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Lactic Acidemia
Homo sapiens
Matched Proteins: Alanine aminotransferase 1 … Mitochondrial pyruvate carrier 1
Matched Protein Synonyms: GPT 1 … Glutamate pyruvate transaminase 1 … Glutamic--alanine transaminase 1 … Glutamic--pyruvic transaminase 1
Matched Compound Synonyms: 1-amino-propane-1,3-dicarboxylate … 1-amino-propane-1,3-dicarboxylic acid … 1-aminopropane-1,3-dicarboxylate … 1-aminopropane-1,3-dicarboxylic acid … Hydrocarbonate(1-)
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SMP0000618
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Fosphenytoin (Antiarrhythmic) Metabolism Pathway
Homo sapiens
Matched Description: prepared in 40% propylene glycol and 10% ethanol at pH 12. This formulation exhibited a range of toxic
Matched Proteins: Beta-1-syntrophin … Alpha-1-syntrophin
Matched Protein Synonyms: 59 kDa dystrophin-associated protein A1 basic component 1 … 59 kDa dystrophin-associated protein A1 acidic component 1 … Pro-TGF-alpha cytoplasmic domain-interacting protein 1 … Syntrophin-1
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SMP0000345
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Congenital Erythropoietic Porphyria (CEP) or Gunther Disease
Homo sapiens
Matched Description: bone marrow transplants or stem cell treatment. It is estimated that CEP affects less than 1 in 1,000,000 individuals.
Matched Proteins: Heme oxygenase 1
Matched Protein Synonyms: 5-aminolevulinic acid synthase 1 … Delta-ALA synthase 1 … Delta-aminolevulinate synthase 1 … HO-1
Matched Compound Synonyms: Succino-1-yl-coenzyme a … (sp-4-2)[7-ethenyl-17-formyl-12-[(4e,8e)-1-hydroxy-5,9,13-trimethyl-4,8,12-tetradecatrienyl]-3,8,13 … [sp-4-2-(e,e)]-[7-ethenyl-17-formyl-12-(1-hydroxy-5,9,13-trimethyl-4,8,12-tetradecatrienyl)-3,8,13 … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0000434
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Paclitaxel Action Pathway (old)
Homo sapiens
Matched Proteins: Tubulin beta-1 chain … Multidrug resistance protein 1 … Canalicular multispecific organic anion transporter 1 … Multidrug resistance-associated protein 1
Matched Protein Synonyms: Tubulin K-alpha-1 … ATP-binding cassette sub-family B member 1 … P-glycoprotein 1 … ATP-binding cassette sub-family C member 1
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SMP0125187
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Amitriptyline Norepinephrine Reuptake Inhibitor Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent L-type calcium channel subunit beta-1 … Beta-1 adrenergic receptor
Matched Protein Synonyms: Calcium channel, L type, alpha-1 polypeptide isoform 4 … Calcium channel voltage-dependent subunit beta 1 … Beta-1 adrenoceptor … Beta-1 adrenoreceptor
Matched Compound Synonyms: (r)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … 4-[(1r)-2-amino-1-hydroxyethyl]-1,2-benzenediol … 4-(2-amino-1-hydroxyethyl)-1,2-benzenediol … L-2-amino-1-(3,4-dihydroxyphenyl)ethanol … 1-dehydroascorbate
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SMP0125516
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Metabolism and Physiological Effects of 3-Deoxyglucosone
Homo sapiens
Matched Proteins: Sodium/glucose cotransporter 1
Matched Protein Synonyms: Na(+)/glucose cotransporter 1 … Solute carrier family 5 member 1 … Aldo-keto reductase family 1 member B1 … Fatty-acid-coenzyme A ligase, very long-chain 1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0125587
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Segawa Syndrome
Homo sapiens
Matched Description: processing of quite a few amino acids, The mutation on GCH1 causes GTP cyclohydrase 1 production to
Matched Compounds: 1-hydroxy-2-Oxopropyl tetrahydropterin
Matched Proteins: GTP cyclohydrolase 1 … GTP cyclohydrolase 1 feedback regulatory protein … Carbonyl reductase [NADPH] 1 … Tryptophan 5-hydroxylase 1
Matched Protein Synonyms: Aldo-keto reductase family 1 member B1 … NADPH-dependent carbonyl reductase 1 … NADPH-dependent carbonyl reductase 1 … Tryptophan 5-monooxygenase 1
Matched Compound Synonyms: (phosphate)n-1 … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
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SMP0125649
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Porphyria Variegata (PV)
Homo sapiens
Matched Proteins: Heme oxygenase 1
Matched Protein Synonyms: 5-aminolevulinic acid synthase 1 … Delta-ALA synthase 1 … Delta-aminolevulinate synthase 1 … HO-1
Matched Compound Synonyms: Succino-1-yl-coenzyme a … (sp-4-2)[7-ethenyl-17-formyl-12-[(4e,8e)-1-hydroxy-5,9,13-trimethyl-4,8,12-tetradecatrienyl]-3,8,13 … [sp-4-2-(e,e)]-[7-ethenyl-17-formyl-12-(1-hydroxy-5,9,13-trimethyl-4,8,12-tetradecatrienyl)-3,8,13 … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0145420
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Buclizine H1 Antihistamine Neurological Sleep Action Pathway
Homo sapiens
Matched Proteins: Voltage-dependent calcium channel subunit alpha-2/delta-1
Matched Protein Synonyms: Voltage-dependent calcium channel subunit alpha-2-1 … Voltage-dependent calcium channel subunit delta-1 … Voltage-gated calcium channel subunit alpha-2/delta-1 … Calcium channel, L type, alpha-1 polypeptide isoform 5
Matched Compound Synonyms: 1-(p-tert-butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine … 1-(p-tert-butylbenzyl)-4-(4-chloro-a-phenylbenzyl)piperazine … 1-(p-tert-butylbenzyl)-4-(4-chloro-α-phenylbenzyl)piperazine … 1-(p-tert-butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine … 1-(p-tert-butylbenzyl)-4-(4-chloro-a-phenylbenzyl)piperazine
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