SMP0123799
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Acylcarnitine 18-Methyltetracosanoylcarnitine
Homo sapiens
Matched Description: first transported into the cell via the long-chain fatty acid transport protein 1 (FATP1). Once inside … . This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA … acetyl-CoA carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O … -palmitoyltransferase 1, thereby preventing 18-methyltetracosanoylcarnitine from forming and thereby preventing it from being transported into the mitochondria.
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0123806
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Acylcarnitine 14-Methylpentacosanoylcarnitine
Homo sapiens
Matched Description: first transported into the cell via the long-chain fatty acid transport protein 1 (FATP1). Once inside … . This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA … acetyl-CoA carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O … -palmitoyltransferase 1, thereby preventing 14-methylpentacosanoylcarnitine from forming and thereby preventing it from being transported into the mitochondria.
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0123811
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Acylcarnitine 6-Methylpentacosanoylcarnitine
Homo sapiens
Matched Description: transported into the cell via the long-chain fatty acid transport protein 1 (FATP1). Once inside … reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety … carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O-palmitoyltransferase 1
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0123818
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Acylcarnitine 4-Methylpentacosanoylcarnitine
Homo sapiens
Matched Description: transported into the cell via the long-chain fatty acid transport protein 1 (FATP1). Once inside … reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA moiety … carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O-palmitoyltransferase 1
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0123823
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Acylcarnitine 12-Methylpentacosanoylcarnitine
Homo sapiens
Matched Description: first transported into the cell via the long-chain fatty acid transport protein 1 (FATP1). Once inside … . This reaction is facilitated by the long-chain fatty-acid CoA ligase 1 protein, which adds a CoA … acetyl-CoA carboxylase 1 to form malonyl-CoA, which inhibits the action of carnitine O … -palmitoyltransferase 1, thereby preventing 12-methylpentacosanoylcarnitine from forming and thereby preventing it from being transported into the mitochondria.
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0123825
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Acylcarnitine (3R)-3,5-dihydroxy-3-methylpentanoylcarnitine
Homo sapiens
Matched Description: protein 1 (FATP1). Once inside the cell it undergoes a reaction to form an acyl-CoA derivative called … CoA ligase 1 protein, which adds a CoA moiety to appropriate acyl groups. Many acyl-CoA groups will … can be catalyzed by acetyl-CoA carboxylase 1 to form malonyl-CoA, which inhibits the action of … carnitine O-palmitoyltransferase 1, thereby preventing (3R)-3,5-dihydroxy-3-methylpentanoylcarnitine
Matched Proteins: Long-chain-fatty-acid--CoA ligase 1 … Carnitine O-palmitoyltransferase 1, liver isoform … Acetyl-CoA carboxylase 1 … Long-chain fatty acid transport protein 1
Matched Protein Synonyms: Acyl-CoA synthetase 1 … LACS 1 … Long-chain acyl-CoA synthetase 1 … Palmitoyl-CoA ligase 1
Matched Compound Synonyms: 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium … 3-carboxy-2-hydroxy-n,n,n-trimethyl-1-propanaminium hydroxide, inner salt … 1-carnitine
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SMP0536142
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TGF beta SMAD Signaling
Homo sapiens
Matched Description: The TGF-β pathway is initiated when TGF-β activates TGF-β receptors (type-1/2) on the cell surface … . However, the pathway is also tightly regulated. SMAD 6/7 interacts with SMURF 1/2, which acts as a
Matched Proteins: Transforming growth factor beta-1 … TGF-beta receptor type-1
Matched Protein Synonyms: TGFR-1 … TGFR-1 … SubName: SMAD specific E3 ubiquitin protein ligase 1 … SubName: SMAD specific E3 ubiquitin protein ligase 1, isoform CRA_c
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SMP0063777
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Nitric Oxide Signaling Pathway
Homo sapiens
Matched Proteins: Glutamate [NMDA] receptor subunit zeta-1 … Glutamate [NMDA] receptor subunit epsilon-1 … Calmodulin-1 … Inositol 1,4,5-trisphosphate receptor type 1
Matched Protein Synonyms: IP3 receptor isoform 1 … IP3R 1 … Type 1 InsP3 receptor … Type 1 inositol 1,4,5-trisphosphate receptor
Matched Compound Synonyms: Nitrite(1-) … Nitrous acid, ion(1-)
Neurological Signaling
Cellular Response
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SMP0410534
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Galactose Metabolism
Escherichia coli str. K-12 substr. MG1655
Matched Description: glucose -1-phosphate through a phosphoglucomutase-1. The glucose -1-phosphate is transformed into a … uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine … galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1 … resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose … 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate
Matched Compounds: Galactose 1-phosphate … β-D-glucose 1-phosphate … α-D-glucose-1-phosphate
Matched Proteins: Phosphoglucomutase-1 … Aldose 1-epimerase … Galactose-1-phosphate uridylyltransferase … UTP--glucose-1-phosphate uridylyltransferase_ … putative aldose 1-epimerase
Matched Protein Synonyms: Glucose phosphomutase 1 … PGM 1 … Glucose phosphomutase 1 … PGM 1
Matched Compound Synonyms: A-d-galactopyranose 1-phosphate … A-d-galactopyranose 1-phosphoric acid … Alpha-d-galactopyranose 1-phosphoric acid … α-d-galactopyranose 1-phosphate … α-d-galactopyranose 1-phosphoric acid
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SMP0413608
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Galactose Metabolism
Escherichia coli DH1
Matched Description: glucose -1-phosphate through a phosphoglucomutase-1. The glucose -1-phosphate is transformed into a … uridine diphosphate glucose through UTP--glucose-1-phosphate uridylyltransferase. The product, uridine … galactokinase, hence producing galactose 1 phosphate. On the other side of the pathway, a gluose-1 … resulting in a alpha-D-glucose-1-phosphate, an isomer of Glucose 1-phosphate, or an isomer of Beta-D-glucose … 1-phosphate) interacts with UTP and a hydrogen ion in order to produce a uridine diphosphate
Matched Compounds: Galactose 1-phosphate … β-D-glucose 1-phosphate … α-D-glucose-1-phosphate
Matched Proteins: Phosphoglucomutase-1 … Aldose 1-epimerase … Galactose-1-phosphate uridylyltransferase … UTP--glucose-1-phosphate uridylyltransferase_ … putative aldose 1-epimerase
Matched Protein Synonyms: Glucose phosphomutase 1 … PGM 1 … Glucose phosphomutase 1 … PGM 1
Matched Compound Synonyms: A-d-galactopyranose 1-phosphate … A-d-galactopyranose 1-phosphoric acid … Alpha-d-galactopyranose 1-phosphoric acid … α-d-galactopyranose 1-phosphate … α-d-galactopyranose 1-phosphoric acid
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