SMP0120549
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Hypercholesterolemia
Mus musculus
Matched Description: effective. It is estimated that hypercholesterolemia affects 1 in 500 individuals in most countries.
Matched Proteins: Isopentenyl-diphosphate Delta-isomerase 1 … UDP-glucuronic acid decarboxylase 1
Matched Compound Synonyms: 3-methyl-2-buten-1-ol pyrophosphate … 3-methyl-2-buten-1-ol trihydrogen pyrophosphate … (2e)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0120573
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Cholesteryl Ester Storage Disease
Mus musculus
Matched Proteins: Isopentenyl-diphosphate Delta-isomerase 1 … UDP-glucuronic acid decarboxylase 1
Matched Compound Synonyms: 3-methyl-2-buten-1-ol pyrophosphate … 3-methyl-2-buten-1-ol trihydrogen pyrophosphate … (2e)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0120794
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Mevalonic Aciduria
Rattus norvegicus
Matched Proteins: Isopentenyl-diphosphate Delta-isomerase 1 … Methylsterol monooxygenase 1 … Sterol O-acyltransferase 1
Matched Compound Synonyms: 3-methyl-2-buten-1-ol pyrophosphate … 3-methyl-2-buten-1-ol trihydrogen pyrophosphate … (2e)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0120575
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Mevalonic Aciduria
Mus musculus
Matched Proteins: Isopentenyl-diphosphate Delta-isomerase 1 … UDP-glucuronic acid decarboxylase 1
Matched Compound Synonyms: 3-methyl-2-buten-1-ol pyrophosphate … 3-methyl-2-buten-1-ol trihydrogen pyrophosphate … (2e)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0120735
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Smith-Lemli-Opitz Syndrome (SLOS)
Rattus norvegicus
Matched Proteins: Isopentenyl-diphosphate Delta-isomerase 1 … Methylsterol monooxygenase 1 … Sterol O-acyltransferase 1
Matched Compound Synonyms: 3-methyl-2-buten-1-ol pyrophosphate … 3-methyl-2-buten-1-ol trihydrogen pyrophosphate … (2e)-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-b-d-ribofuranosylnicotinamide … 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
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SMP0063588
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Pentose Phosphate Pathway
Mus musculus
Matched Description: into an oxidative phase and a non-oxidative phase. Reactions 1-3 form the oxidative phase and … reactions are as follows: reaction 1 where glucose-6-phosphate 1-dehydrogenase converts glucose 6
Matched Compounds: Ribose 1-phosphate … Deoxyribose 1-phosphate
Matched Proteins: Transketolase-like protein 1
Matched Compound Synonyms: 2'-(dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-d-ribofuranosyl-3-pyridinecarboxamide … Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) p'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide … D-ribose 1-phosphate … D-ribose 1-phosphoric acid
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SMP0069666
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Cardiolipin Biosynthesis CL(18:0/18:2(9Z,12Z)/18:1(11Z)/18:0)
Mus musculus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: CDP-DG(18:1(11Z)/18:0) … CL(18:0/18:2(9Z,12Z)/18:1(11Z)/18:0)
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0069671
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Cardiolipin Biosynthesis CL(18:0/18:2(9Z,12Z)/18:1(9Z)/18:1(11Z))
Mus musculus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: CDP-DG(18:1(9Z)/18:1(11Z)) … CL(18:0/18:2(9Z,12Z)/18:1(9Z)/18:1(11Z))
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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SMP0069985
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Phosphatidylcholine Biosynthesis PC(14:0/18:1(11Z))
Mus musculus
Matched Compounds: DG(14:0/18:1(11Z)/0:0) … PE(14:0/18:1(11Z)) … PS(14:0/18:1(11Z)) … PE-NMe(14:0/18:1(11Z)) … PE-NMe2(14:0/18:1(11Z))
Matched Proteins: Ethanolaminephosphotransferase 1
Matched Compound Synonyms: 2-amino-1-ethanol … 2-aminoethan-1-ol … 1-myristoyl-2-vaccenoyl-sn-glycerol … Dag(14:0/18:1) … Dag(32:1)
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SMP0069273
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Cardiolipin Biosynthesis CL(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/20:4(5Z,8Z,11Z,14Z)/16:1(9Z))
Mus musculus
Matched Description: enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn … -glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic acid or LPA). Third, the … enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2
Matched Compounds: LysoPA(16:1(9Z)/0:0) … PA(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)) … CDP-DG(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)) … PGP(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)) … PG(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z))
Matched Compound Synonyms: 1-hydroxy-3-(phosphonooxy)-2-propanone … 1-hydroxy-3-(phosphonooxy)acetone … 1,3-dihydroxyacetone 1-phosphoric acid … 3-carbamoyl-1-beta-d-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt … 3-carbamoyl-1-beta-delta-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt
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