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Matched Description: Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the … , where it passes through hepatic portal circulation, and enters the bloodstream and travels to act on … cardiomyocytes. In bronchial and vascular smooth muscle, nebivolol can compete with epinephrine for … activates cAMP synthesis, which in turn activates PKA production, which then activates SRC and nitric … oxide synthase, its inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase

Matched Description: with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also … convoluted tubule (DCT), the regulation of ions such as sodium, potassium, calcium, chloride and … , which pumps Na+ into the interstitium-blood area and K+ into the epithelial cell; the Na+/Ca2 … + exchanger, which pumps Na+ into the cell and Ca2+ into the interstitium-blood; and the chloride … transports K+ out of the epithelial cell and a Na+/Cl- cotransporter which transports Na+ and Cl

Matched Description: targets the nonstructural protein 5A (NS5A) and causes a decrease in serum HCV RNA levels … lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 … and occludin, which mediate the late steps of viral entry. The virus is internalized by clathrin … -dependent endocytosis. RNA is released from the mature Hepatitis C virion and translated at the rough … endoplasmic reticulum into a single Genome polyprotein. The genome polyprotein is cleaved by host and

Matched Description: Saquinavir is an HIV protease inhibitor used in combination with ritonavir and other antiretroviral … protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical … bioavailability and subsequent serum concentrations of saquinavir, thus dramatically improving antiviral … activity. The HIV virus binds and penetrates the host cell. Viral RNA is transcribed into viral … DNA via reverse transcriptase. Viral DNA enters the host nucleus and is integrated into the host DNA

Matched Description: rhinitis and chronic idiopathic urticaria. H1-antihistamines interfere with the agonist action of … histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat … conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 … vessels, and in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate

Matched Description: Bilastine is a peripheral histamine H1-antagonist used to treat seasonal allergic rhinitis and … H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such … as allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors … in T-cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and … in smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines interfere with

Matched Description: such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax … and are administered to attenuate inflammatory process in order to treat conditions such as allergic

Matched Description: Antazoline is an antihistamine agent used for the symptomatic treatment of nasal congestion and … receptor and are administered to attenuate inflammatory process in order to treat conditions such as … allergic rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T … -cells to inhibit the immune response, in blood vessels to constrict dilated blood vessels, and in … smooth muscles of lungs and intestines to relax those muscles. H1-antihistamines interfere with the

Matched Description: Pheniramine is an antihistamine used to treat allergic rhinitis and pruritus. H1-antihistamines … interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate … , and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune response, in … blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to … receptor and are administered to attenuate inflammatory process in order to treat conditions such as

Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes … . Carvedilol is a racemic mixture where the S(-) enantiomer is a beta adrenoceptor blocker and the R … (+) enantiomer is both a beta and alpha-1 adrenoceptor blocker. In bronchial and vascular smooth … production, which then activates SRC and nitric oxide synthase, its inhibition causes the inhibition … of cAMP, PKA, SRC and nitric oxide synthase signaling. Following this chain of reactions, we see