SMP0125805
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Refsum Disease
Homo sapiens
Matched Description: Atactica Polyneurtiformis; Hereditary Motor and Sensory Neuropathy IV; HSMN4; Adult Refsum Disease I … chromosome 10 (adult Refsum disease I), and by mutation of the PEX7 gene. A defect in phytanoyl-CoA … due to the inability for phytanic acid to undergo alpha and beta oxidation. Symptoms include anosmia … , ataxia, nystagmus, neurological deterioration and peripheral neuropathy. Adult Refsum disease is … distinctly different from Infantile Refsum disease both genetically and phenotypically. Infantile
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SMP0125317
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Cephalexin Action Pathway (New)
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Matched Description: infections. These infections include respiratory tract infections, otitis media, skin and skin structure … infections, bone infections, and genitourinary tract infections.
Cephalexin is administered orally as … responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D … -alanine and D-aspartic acid in bacterial cell walls. Inhibition of this protein leads to upregulation … of autolytic enzymes and inhibition of cell wall synthesis. Cephalexin eventually leads to cell death
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SMP0125853
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Amodiaquine Action Pathway
Homo sapiens
Matched Description: Amodiaquine, a 4-aminoquinoline similar to chloroquine in structure and activity, is an … as chloroquine, and is effective against some chloroquine-resistant strains, although resistance to … , and produce vasodilatation with resultant hypotension. They depress respiration and cause diplopia … , dizziness and nausea.
The mechanism of action of Amodiaquine is not certain, but like other … parasite from converting it to a less toxic form. This complex is toxic and disrupts membrane function. This eventually causes parasite death.
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SMP0126698
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Brexpiprazole Dopamine Agonist Action Pathway
Homo sapiens
Matched Description: 5-HT1A and dopamine D2 receptors, and antagonist activity at 5-HT2A receptors. Brexpiprazole is … predominantly, a 5-HT1A, D2, and D3 partial agonist and a 5-HT2A, 5-HT2B, 5-HT7, alpha1A, alpha1B … , alpha1D, and alpha2C antagonist with a chemical formula of 7-{4-[4-(1-Benzothiophen-4-yl) piperazin-1-yl … schizophrenia in patients 13 years of age and older. Brexpiprazole is also indicated for the treatment
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SMP0355112
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Acetate Metabolism
Bacteroides intestinalis
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0358108
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Acetate Metabolism
Escherichia coli O111:H- str. 11128
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0358101
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Acetate Metabolism
Escherichia coli ED1a
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0355278
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Acetate Metabolism
Paraprevotella clara YIT 11840
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0355444
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Acetate Metabolism
Paenibacillus lactis 154
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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SMP0355331
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Acetate Metabolism
Fusobacterium periodonticum 1_1_41FAA
Matched Description: acetyltransferase resulting in the release of a coenzyme A and an acetyl phosphate. The latter compound in … turn reacts with ADP through an acetate kinase resulting in the release of an ATP and an acetate … . The acetate reacts with ATP and coenzyme A through an acetyl-CoA synthase resulting in the release of … a diphosphate, an AMP and an acetyl-CoA.
Acetyl-CoA can be biosynthesized by acetoacetate reacting … with an acetyl-CoA through an acetoacetyl-CoA transferase resulting in the release of an acetate and
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