Browsing Search Results

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: synthesis of fungi cell membranes. It was approved by the FDA (USA) in November 2013 and is marketed under … Trichophyton rubrum and Epidermophyton floccosum, most likely by altering their fungal cell membranes … increasing fluidity and preventing growth of new cells. This leads to cell lysis which causes it to collapse and die.

Matched Description: Primaquine is an minoquinoline antimalarial is a radical cure and prevent relapse of vivax and … happens haemoglobin is divided into two parts; haem and globin. Haem is toxic to the malaria … action is unclear, primaquine may bind to and alter the properties of protozoal DNA.

Matched Description: in order to confirm results, safety and confirm the mechanism of action.

Matched Description: and has both structural and signalling roles. In eukaryotes, there exist two phosphatidylcholine … biosynthesis pathways: the Kennedy pathway and the methylation pathway. The Kennedy pathway begins … -choline and subsequently phosphatidylcholine. It is the major synthesis route in animals. The

Matched Description: antigen and displayed the resulting peptide antigen fragments on their surface MHC molecules. These … complex from these APCs binds to the TCR of a given T-cell and then, through a series of signalling … ), diacylglycerol (DAG) and others that are essential for the activation of PKC-theta (protein kinase C-theta), and … and beta subunit) and the CD3 glycoprotein complex (PMID: 19132916). An early event in TCR activation … and phosphorylation of other proteins. For instance, the phosphorylation of SLP-76 by Zap-70 promotes

Matched Description: (NDRI) used most commonly as a treatment for major depressive disorder (MDD), and seasonal affective … works with other drugs to help with other neurological disorders such as seizures, and ADHD with … bipolar comorbidity. Bupropion works by weakly inhibiting dopamine and norepinephrine transporters … mainly occurs in the substantia nigra, ventral tegmental area, and hypothalamus which are all parts of … into cAMP which activates PKA which causes neuronal excitability. This helps regulate mood and

Matched Description: , and reduce conduction velocity of the atrioventricular node (AV node). However, they have little … such as Giα, and a complex of two tightly linked proteins called Gβ and Gγ in a Gβγ complex. When not … stimulated by a receptor, Gα is bound to GDP and to Gβγ to form the inactive G protein trimer.When … activated receptor acts as a guanine nucleotide exchange factor to promote GDP release from and GTP … binding to Gα, which drives dissociation of GTP-bound Gα from Gβγ. GTP-bound Gα and Gβγ are then

Matched Description: macromolecules that function as enzymes, antibodies, and cellular structural components. Although synthesis … synthesis, is transported out of the nucleus and becomes bound to ribosomes in the cytoplasm or … and a three-nucleotide sequence called the anticodon that forms three complementary base pairs with an … via a reaction termed peptide condensation, and the tRNAs, no longer carrying amino acids, are released.

Matched Description: Farnesene biosynthesis is a pathway that begins in the chloroplast and ends in the cytosol by which … all are sesquiterpenes. alpha-Farnesene and beta-farnesene are isomers, differing by the location of … requires FAD, NAD(P)H, and a divalent cation (e.g. magnesium) as cofactors. Second … farnesyl diphosphate. Farnesyl diphosphate then must be transported out of the chloroplast and into