SMP0059702
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Phenbenzamine H1-Antihistamine Action
Homo sapiens
Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and
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SMP0057581
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Triprolidine H1-Antihistamine Action
Homo sapiens
Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0060743
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Quifenadine H1-Antihistamine Action
Homo sapiens
Matched Description: action of histamine at the H1 receptor and are administered to attenuate inflammatory process in … order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing … the activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression … of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore
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SMP0062884
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Quetiapine H1-Antihistamine Action
Homo sapiens
Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of pro … -inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering
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SMP0061190
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Phenindamine H1-Antihistamine Action
Homo sapiens
Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause
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SMP0126107
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Racepinephrine B2-Adrenergic Bronchodilation Action Pathway
Homo sapiens
Matched Description: Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a … rapid onset and short duration and acts as a smooth muscle relaxant and constrictor in different … to relax the smooth muscle of the lungs, and it is also an alpha-1 adrenergic receptor agonist which … the hydrostatic pressure and consequently bronchial mucosal edema. Racepinephrine is a racemic … mixture consisting of d-Epinephrine and l-Epinephrine enantiomers. Epinephrine is a non-selective α- and β
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SMP0175127
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Olopatadine H1-Antihistamine Immune Response Action Pathway
Homo sapiens
Matched Description: Olopatadine is a histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune … response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and … at the H1 receptor and are administered to attenuate inflammatory process in order to treat
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SMP0126403
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Anisotropine Methylbromide M2 GI Tract Relaxation Action Pathway
Homo sapiens
Matched Description: methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the … tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and … gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial … secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate … . Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to
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SMP0122251
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Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer
Pseudomonas aeruginosa
Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol.
2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion
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SMP0126642
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Streptokinase Action Pathway (new)
Homo sapiens
Matched Description: Streptokinase is a bacterial protein that is fibrinolytic and used to break down blood clots in … myocardial infarction, pulmonary embolism and venous thromboembolism. It is administered intravenously … and travels through the bloodstream to target blood clots. Streptokinase does this by converting … anticoagulant and antiplatelet activity, herbs and supplements with a similar activity should be … avoided such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba.
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