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Search for '28cortisol oh aldosterone 20 and subjected 3ametabolic' in 'all pathways' in 'all' returned 290407 results

SMP0059702

Pw060645 View Pathway
Metabolite

Phenbenzamine H1-Antihistamine Action

Homo sapiens

  • Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … phospholipase C and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation … and the expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … further histamine release. First-generation antihistamines readily cross the blood-brain barrier and

  • Drug Action

    SMP0057581

    Pw058506 View Pathway
    Metabolite

    Triprolidine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause

  • Drug Action

    SMP0060743

    Pw061693 View Pathway
    Metabolite

    Quifenadine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: action of histamine at the H1 receptor and are administered to attenuate inflammatory process in … order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing … the activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression … of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore

  • Drug Action

    SMP0062884

    Pw063841 View Pathway
    Metabolite

    Quetiapine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: histamine at the H1 receptor and are administered to attenuate inflammatory process in order to … treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria. Reducing the … activity of the NF-κB immune response transcription factor through the phospholipase C and the … phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the expression of pro … -inflammatory cytokines, cell adhesion molecules, and chemotactic factors. Furthermore, lowering

  • Drug Action

    SMP0061190

    Pw062141 View Pathway
    Metabolite

    Phenindamine H1-Antihistamine Action

    Homo sapiens

  • Matched Description: agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory … process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and urticaria … and the phosphatidylinositol (PIP2) signalling pathways also decreases antigen presentation and the … expression of pro-inflammatory cytokines, cell adhesion molecules, and chemotactic factors … histamine release. First-generation antihistamines readily cross the blood-brain barrier and cause

  • Drug Action

    SMP0126107

    Pw127686 View Pathway
    Metabolite

    Racepinephrine B2-Adrenergic Bronchodilation Action Pathway

    Homo sapiens

  • Matched Description: Asthmanefrin and is orally inhaled to act on both alpha and beta adrenergic receptors. This drug has a … rapid onset and short duration and acts as a smooth muscle relaxant and constrictor in different … to relax the smooth muscle of the lungs, and it is also an alpha-1 adrenergic receptor agonist which … the hydrostatic pressure and consequently bronchial mucosal edema. Racepinephrine is a racemic … mixture consisting of d-Epinephrine and l-Epinephrine enantiomers. Epinephrine is a non-selective α- and β

  • Drug Action

    SMP0175127

    Pw176814 View Pathway
    Metabolite

    Olopatadine H1-Antihistamine Immune Response Action Pathway

    Homo sapiens

  • Matched Description: Olopatadine is a histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. H1 … -antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered … conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to inhibit the immune … response, in blood vessels to constrict dilated blood vessels, and in smooth muscles of lungs and … at the H1 receptor and are administered to attenuate inflammatory process in order to treat

  • Drug Action

    SMP0126403

    Pw127999 View Pathway
    Metabolite

    Anisotropine Methylbromide M2 GI Tract Relaxation Action Pathway

    Homo sapiens

  • Matched Description: methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the … tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and … gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial … secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate … . Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to

  • Drug Action

    SMP0122251

    Pw123559 View Pathway
    Metabolite

    Pyruvate to Cytochrome bd Terminal Oxidase Electron Transfer

    Pseudomonas aeruginosa

  • Matched Description: pyruvate and 2 water molecules reacting in a pyruvate oxidase resulting in the release of 4 electrons into … the inner membrane, and releasing 2 carbon dioxide molecules , 2 acetate and 4 hydrogen ion into the … cytosol. 2 ubiquinone,4 hydrogen ion and 4 electron ion react resulting in the release of 2 … bd-I terminal oxidase and releasing 4 electrons through the enzyme. Oxygen and 4 hydrogen ion

  • Metabolic

    SMP0126642

    Pw128244 View Pathway
    Metabolite

    Streptokinase Action Pathway (new)

    Homo sapiens

  • Matched Description: Streptokinase is a bacterial protein that is fibrinolytic and used to break down blood clots in … myocardial infarction, pulmonary embolism and venous thromboembolism. It is administered intravenously … and travels through the bloodstream to target blood clots. Streptokinase does this by converting … anticoagulant and antiplatelet activity, herbs and supplements with a similar activity should be … avoided such as garlic, ginger, bilberry, danshen, piracetam and ginkgo biloba.

  • Drug Action