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Matched Description: hepatocytes via receptor-mediated endocytosis. The lipoviroparticles attach to LDL-R and SR-B1, and … then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps … mature Hepatitis C virion and translated at the rough endoplasmic reticulum into a single Genome … polyprotein. The genome polyprotein is cleaved by host and viral proteases into 10 viral proteins. The … nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the

Matched Description: and kallikrein. The drug is slowly metabolized by lysosomal enzymes and is eliminated through the … leading to various complications and in some cases death.

Matched Description: (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene. It has also been found to affect the … and norepinephrine to bind to the receptors. These receptors regulate attention, movement, and … reuptake transporters of both dopamine and norepinephrine which prolongs their duration in the … -hydroxylase. Norepinephrine is then transported to the prefrontal cortex and released into the synapse when … the neuron is stimulated and fires. Methylphenidate binds and blocks the sodium-dependent

Matched Description: drug class. This drug is indicated in the treatment of leprosy, and urinary, and respiratory tract … infections. It shows bacteriostatic effects against gram-positive and gram-negative bacteria

Matched Description: tachycardias, and atrial fibrillation. It can be administered intravenously or orally, where it … passes through hepatic portal circulation, and enters the bloodstream and travels to act on … cardiomyocytes. In bronchial and vascular smooth muscle, alprenolol can compete with epinephrine for beta-2 … synthesis, which in turn activates PKA production, which then activates SRC and nitric oxide … synthase, its inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase signaling

Matched Description: through hepatic portal circulation, and enters the bloodstream and travels to act on cardiomyocytes. In … bronchial and vascular smooth muscle, bisoprolol can compete with epinephrine for beta adrenergic … synthesis, which in turn activates PKA production, which then activates SRC and nitric oxide synthase, its … inhibition causes the inhibition of cAMP, PKA, SRC and nitric oxide synthase signaling. Following … , the inhibition of SRC in essence causes the activation of Caspase 3 and Caspase 9. This Caspase

Matched Description: procedures to assist in the visualization of blood vessels. It is intravenously injected and is … commonly marketed under the trade name Omniscan and used in MRI to visualize lesions with abnormal … vascularity in the brain (intracranial lesions), spine, and associated tissues. There is no detectable biotransformation or decomposition of gadodiamide.

Matched Description: the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract. Ofloxacin … inhibits DNA gyrase (topoisomerase II) and topoisomerase IV. These proteins prevent supercoiling in … bacterial DNA. The inhibition of DNA gyrase (topoisomerase II) and topoisomerase IV causes

Matched Description: infections in various locations, including the respiratory tract, abdomen, skin, and female genital … tracts. Cefoperazone exhibits a bactericidal mode of action. It works by binding to and inhibiting … synthesis by interfering with the lengthening and strengthening of the peptidoglycan portion of the cell wall, thereby inhibiting cell wall synthesis.

Matched Description: with the agonist action of histamine at the H1 receptor and are administered to attenuate … inflammatory process in order to treat conditions such as allergic rhinitis, allergic conjunctivitis, and … vessels to constrict dilated blood vessels, and in smooth muscles of lungs and intestines to relax … those muscles. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and … rhinitis, allergic conjunctivitis, and urticaria. H1-antihistamines act on H1 receptors in T-cells to